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OPTIMIZATION OF GELATIN CONCENTRATION IN TABLET WITH AFRICAN LEAF EXTRACT (Vernonia Amygdalina) Wahlanto, Panji; Yusuf, Anna L; Nugraha, Davit; Siti Rahmah KR; Dissya Alifia
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1614

African plants, especially the leaves, are a type of medicinal plant used by the community. This African leaf contains active lavonoids that can be used to measure blood glucose levels. Tablet preparations have the advantage that they are easy to consume, so in this study African leaves (Vernonia Amygdalina) were made into tablets. The ratios of the binder used were 4%, 5%, and 6%. After obtaining the evaluation results, data analysis was performed using the Kruskal–Wallis SPSS statistical test with a confidence level of 95%. The evaluation results showed that the three formulations only fulfilled the respective requirements, namely for the angle of repose test between 16.6° - 21.3°, the granule thickening test of all formulations is below <20% and meets the requirements, the weight uniformity test has an average of 191-192 mg meeting the predetermined requirements, namely not more than 3 times with an average of 7.35 -7.36 mm and a thickness of mean + SD 0,47 the disintegration time test of all formulations stated that they met the requirements that had been determined that is not more than 15 minutes, the friability test only on formulation III which met the requirements to get a result of 0.54% in formulations I and II did not meet the specified requirements, the hardness test of all formulations did not meet the specified test requirements. Keywords: African leaf extract, gelatin, tablets.

Hedonic Evaluation of Red Ginger Extract Gummy Candy as an Innovative Approach to Prevent Stunting in Children Under Five Heryani, Heni; Nugraha, Davit; Lestari, Lusi; Rahmah Kurnia, Siti; Yusuf, Anna L
Genius Journal Vol. 5 No. 2 (2024): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v5i2.425

Introduction: Stunting can have long-term impacts on children's health and development. Preventing stunting in children under five requires a comprehensive approach, including adequate and balanced nutritional intake. One of the natural ingredients commonly used in traditional medicine is red ginger (Zingiber officinale var. rubrum), which contains phytochemical compounds, vitamins, minerals, and fiber beneficial for maintaining vascular and digestive health. Gummy candy formulations have the advantage of high acceptability and appeal, particularly for children who find it difficult to consume medicine. Objective: This study aims to determine the level of preference for gummy candy made with red ginger extract as a strategy to prevent stunting in children under five. Method: The study employed an experimental design using a sensory hedonic test. The inclusion criteria included mothers with toddlers. A total of 20 participants were selected using an incidental sampling technique. Result: The findings indicated that participants showed a high level of preference for red ginger extract gummy candy. On average, the gummy candy was rated as highly appealing in terms of appearance, taste, aroma, and texture. Conclusion: Red ginger extract gummy candy has significant potential to be well-accepted by children under five. Further improvements are recommended, particularly in enhancing the gummy candy's appearance and incorporating more varied shapes to increase its appeal.

Upaya Preventif Pertama pada Emesis Gravidarum dengan Pembudidayaan Tanaman Jahe Merah di Kelompok Wanita Tani Sri Mandiri Sindangkasih Asmarani, Sri Utami; Sandriani, Sandriani; Yusuf, Anna L; Purwati, Ayu Endang
Kolaborasi: Jurnal Pengabdian Masyarakat Vol 5 No 1 (2025): Kolaborasi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/kolaborasi.v5i1.464

Introduction: Pregnancy is a condition that requires psychological and physiological adaptation to the influence of pregnancy hormones and mechanical stress due to the enlargement of the uterus and other tissues. Pregnant women will experience changes that make them uncomfortable, one of which is emesis gravidarum. The complaint of nausea and vomiting in emesis gravidarum is physiological, but if this complaint is not resolved immediately, it will become pathological. Objective: This community service was carried out to increase the knowledge and skills of the KWT Sri Mandiri in the cultivation of red ginger and the use of ginger plants as a non-pharmacological therapy for the initial treatment of emesis gravidarum. Method: The method used in this community service involves 3 phases of activity, namely preparation, implementation and evaluation. Result: The results of the community service activities carried out at the Sri Mandiri Sindangkasih Women Farmers Group (KWT) showed that there was an increase in the knowledge and skills of the Sri Mandiri Women Farmers Group (KWT) on red ginger cultivation and the use of ginger plants as a non-pharmacological therapy for the first treatment of emesis gravidarum. Conclusion: The conclusion from the implementation of this community service is that all stages of activities on red ginger cultivation and use of ginger plants to reduce emesis gravidarum can be carried out well supported by the enthusiasm of KWT Sri Mandiri.

Hedonic Evaluation of Red Ginger Extract Gummy Candy as an Innovative Approach to Prevent Stunting in Children Under Five Heryani, Heni; Nugraha, Davit; Lestari, Lusi; Rahmah Kurnia, Siti; Yusuf, Anna L
Genius Journal Vol. 5 No. 2 (2024): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v5i2.425

Introduction: Stunting can have long-term impacts on children's health and development. Preventing stunting in children under five requires a comprehensive approach, including adequate and balanced nutritional intake. One of the natural ingredients commonly used in traditional medicine is red ginger (Zingiber officinale var. rubrum), which contains phytochemical compounds, vitamins, minerals, and fiber beneficial for maintaining vascular and digestive health. Gummy candy formulations have the advantage of high acceptability and appeal, particularly for children who find it difficult to consume medicine. Objective: This study aims to determine the level of preference for gummy candy made with red ginger extract as a strategy to prevent stunting in children under five. Method: The study employed an experimental design using a sensory hedonic test. The inclusion criteria included mothers with toddlers. A total of 20 participants were selected using an incidental sampling technique. Result: The findings indicated that participants showed a high level of preference for red ginger extract gummy candy. On average, the gummy candy was rated as highly appealing in terms of appearance, taste, aroma, and texture. Conclusion: Red ginger extract gummy candy has significant potential to be well-accepted by children under five. Further improvements are recommended, particularly in enhancing the gummy candy's appearance and incorporating more varied shapes to increase its appeal.

Study of Taurine Content in Energy Drink Powders: UV-Vis Spectrophotometric Method Ramdan, Siti Rahmah Kurnia; Athollah, Rifqi Nabil; Yusuf, Anna L; Nugraha, Davit; Wahlanto, Panji
INDOGENIUS Vol 4 No 2 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i2.593

Background and Objective: Energy drinks are commonly consumed as a fast and affordable solution to fatigue, especially among adolescents and young adults. However, public knowledge about their appropriate use and the health risks of excessive intake remains limited. Taurine (2-aminoethanesulfonic acid), a conditionally essential amino acid found in many energy drinks, contributes to several physiological functions. Excessive intake of taurine may adversely affect kidney function. Method: The method of this study using UV-Vis spectrophotometry. A 0.1% ninhydrin solution was used for qualitative testing, while UV-Vis spectrophotometry was employed for quantitative measurement. Proteins were precipitated using Carrez I and Carrez II reagents before analysis. Results: A purplish-blue color change in the qualitative test confirmed the presence of taurine. Quantitative analysis revealed taurine concentrations of 0.025% and 0.012% in the two samples. Conclusion: The results validate UV-Vis spectrophotometry as a practical and dependable technique for analyzing taurine, highlighting the importance of educating the public on the associated health risks of excessive consumption.

Isolasi dan Identifikasi Kurkumin Ekstrak Etanol Temulawak (Curcuma xanthorriza Roxb.) dengan Metode Kromatografi Kolom Ramdan, Siti Rahmah Kurnia; Asih, Aas Catia; Yusuf, Anna L; Nugraha, Davit; Indriastuti, Marlina; Wahlanto, Panji
Pharmacogenius Journal Vol 3 No 3 (2024): Pharmacy Genius
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/pharmgen.v3i3.427

Pendahuluan: Temulawak telah banyak digunakan oleh masyarakat dalam pengobatan tradisional dengan berbagai manfaat. Rimpang temulawak mengandung kurkumin, serat, pati, kalium oksalat, minyak atsiri, flavonoid dan zat-zat tersebut berfungsi sebagai antimikroba, mencegah penggumpalan darah, immunostimulan, anti peradangan, melancarkan metabolisme dan fungsi organ tubuh. Tujuan: Tujuan dari penelitian ini untuk melakukan isolasi kurkumin dari ekstrak etanol 95% temulawak dengan menggunakan kromatografi kolom, kemudian diidentifikasi spektrofotometri UV-Vis pada panjang gelombang 400-800 nm. Metode: Metode penelitian yaitu isolasi kurkumin dengan kromatografi kolom terhadap ekstrak etanol 95% temulawak dengan eluen kloroform:etanol:asam asetat glasial (94:5:1), selanjutnya dilakukan identifikasi dengan spektrofotometri UV-Vis pada panjang gelombang 400nm-800nm. Hasil: Hasil isolasi senyawa kurkumin dari ekstrak temulawak dengan eluen kloroform:etanol:asam asetat glasial (94:5:1) diperoleh dengan menggunakan kromatografi kolom berupa cairan berwarna kuning pekat, kemudian identifikasi dengan spektrofotometri UV Vis dan diperoleh nilai absorbansi tertinggi pada panjang gelombang maksimum 425 nm. Kesimpulan: Dari data tersebut dapat disimpulkan bahwa kurkumin dapat diisolasi dari ekstrak temulawak dengan metode kromatografi kolom dan diidentifikasi dengan Spektrofotometri Uv Vis.

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