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All Journal Indonesian Journal of Medicine Jurnal Pengabdian Pada Masyarakat METHABDI Benih : Journal of Midwifery Jurnal Kedokteran Methodist
Rimbun, Surjadi
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THE RELATIONSHIP BETWEEN ADIPOSE TISSUE FACTORS AND OBESITY UNDERLYING THE OCCURRENCE OF METABOLIC SYNDROME Kusuma, R; Rimbun, Surjadi
Benih : Journal of Midwifery Vol. 4 No. 02 (2025): Benih : Journal of Midwifery
Publisher : Cattleya Darmaya Fortuna

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54209/benih.v4i02.490

Abstract

The growing prevalence of sedentary lifestyles, particularly in urban populations, combined with the widespread consumption of unhealthy foods, has contributed to increasing rates of overweight and obesity (adiposity). These conditions induce pathophysiological disturbances in adipose tissue, which functions as an endocrine organ, thereby leading to metabolic syndrome. Atherogenic dyslipidemia plays a significant role in the progression of atherosclerosis, ultimately increasing the risk of cardiovascular diseases. Furthermore, inflammatory mediators released by dysfunctional adipocytes are associated with the development of certain types of cancer. This review highlights the role of obesity and adipose tissue as fundamental components in the emergence of metabolic syndrome, aiming to strengthen scientific understanding and encourage further research to develop effective strategies for the prevention and management of complex metabolic disorders
KETERKAITAN FAKTOR JARINGAN ADIPOSA DAN OBESITAS YANG MENDASARI TERJADINYA SINDROMA METABOLIK Rita Kusuma; Rimbun, Surjadi
Jurnal Kedokteran Methodist Vol. 18 No. 1 (2025): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v20i1.4716

Abstract

ABSTRACT With the increasing prevalence of physical inactivity, particularly in urban areas, and the widespread consumption of unhealthy foods, the prevalence of overweight and obesity (adiposity) has increased. This condition gives rise to a pathophysiological disorder in adipose tissue, an endocrine organ, known as metabolic syndrome. Atherogenic dyslipidemia significantly contributes to the development of atherosclerosis, which leads to cardiovascular disease. Inflammatory substances released by diseased fat cells also contribute to certain cancers. This review examines obesity and adipose tissue, which are fundamental to the development of metabolic syndrome, to deepen our understanding of metabolic syndrome and encourage further research to develop effective strategies for preventing and managing this complex metabolic disease. Keywords : Adipose tissue, OBESITY, METABOLIC SYNDROME
Co-Authors Anjany, Larasaty Butar-Butar, Harry Chalil, M. Jalaluddin A. Diani Nazma Endy Juli Anto Fadinie, Wulan Hadyanto Lim Hamdi, Tasrif Hutagalung, Sanggam B. Hutahaean, Reinhard J. D. Hutasoit, Eka Samuel P Hutasoit, Eka Samuel P. Irfan Hamdani, Irfan Irina, Sinta Ivonne Ruth Vitamaya Oishi Situmeang Juli Jamnasi Kautsar, Dinda Kembaren, Alfri Yoganta S. Kusuma, R Lubis, Andriamuri P. Manullang, Frengky S. Natalie S., Karen Pasaribu, Sumihar Priccilia, Agnes Bella Rita Kusuma Siahaan, Dwi Lunarta D. S. Siahaan, Jekson Martiar Siahaan, Samuel D. J. Sibarani, Chintya D. P. Silaen, Ester L. R. Silitonga, Hendrika Adriana Simanjuntak, Evirosa Simanjuntak, Evirosa J. Simbolon, Boyke M. Sinaga, Inda M. Sinatra, Jadeny Sitepu, John Frans Situmeang, Ivonne Ruth Vitamaya Oishi Situmorang, Novrina Stephanie S., Kezia Tambunan, Ronald T. H. Tambunan, Ronald Tunggul Hotmarojahan Tanjung, Qodri F. Tarigan, Juliyanti Tarigan, Menang Bastanta Tiji, Widjaya Taufik Tobing, Jerry Fitrio Julianto Tobing, Paul S. M. L. YUNAFRI, ANDRI Zainumi, Cut M.