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All Journal Jurnal Penelitian Humaniora Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL SERAMBI ILMU Jurnal Biology Education Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh Aceh Journal of Health Innovation Jurnal Hurriah: Jurnal Evaluasi Pendidikan dan Penelitian
Nurlena Andalia
Universitas Serambi Mekkah
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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PEMERIKKSAAN EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura.L) PADA HISTOPATOLOGI JANTUNG TIKUS (Rattus novergicus) YANG DIINDUKSI STREPTOZOCIN Nurlena Andalia; M. Ridhwan; Evi Apriana
Aceh Health Sciences Journal Vol 1 No 1 (2024): JUNI 2024
Publisher : LLDIKTI WILAYAH XIII

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64958/ajohi.v1i1.25

Abstract

Daun Kersen (Muntigia calabura L.) adalah salah satu herbal yang yang secara tradisional digunakan untuk menurunkan kadar gula darah pada pasien diabetes melitus. Tujuan penelitian ini untuk mengetahui apakah terdapat pengaruh uji ekstrak etanol daun kersen terhadap histologi hepar tikus putih (Rattus norvegicus) yang diinduksi streptozocin (STZ) Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian naratif, serta eksperimen menggunakan metode Rancangan Acak Lengkap (RAL). Penelitian ini menggunakan 5 kelompok percobaan dengan tiga kali pengulangan. Penelitian ini dilakukan pada tanggal 08 Mei sampai 22 Mei 2023. Objek dalam penelitian ini ialah 30 ekor tikus putih (yang telah diinduksi STZ sehingga menyebabkan diabetes mellitus. Analisis data dilakukan dengan pengamatan gambar melalui histopatologi hepar tikus. Hasil penelitian diperoleh bahwa pada larutan aquades (K1) terlihat gambaran normal sel hepatosit berderet secara radier pada lobulus hepar. Pada K2 (diinduksi STZ 30 mg/kilo Gram BB), sel hepatosit mengalami bengkak keruh dan nekrosis menggunakan inti piknotik, pada K3 (diinduksi STZ 30 mg/kg BB dan + obat metformin), terlihat sedikit sel yang mengalami degenerasi perlemakan dengan terbentuknya vakuolisasi lemak pada sitoplasma sel, di K4 (diinduksi STZ 30 mg/kg BB dan ekstrak daun kersen 10%), menunjukkan sel mengalami degenerasi, adanya interim, pada K5 (diinduksi streptozocin 30 mg/kgBB serta diberikan ekstrak etanol daun kersen 15%), sel hati berbentuk normal, dimana sel hepatosit berderet secara radier dalam lobulus hati. Dengan demikian ekstrak etanol daun kersen berdosis 15%, efektif dalam memperbaiki kerusakan sel di pada tubuh dampak asal zat tosik STZ sehingga dapat menurunkan kadar glukosa darah didalam tubuh.
Development Of Outdoor Learning-Based Independent Flow Teaching Module to Improve Critical Thinking Abilities in Science Learning in Grade VII of SMP 2 Darul Hikmah, Aceh Jaya District Aisyah Aisyah; Jalaluddin Jalaluddin; Ibrahim Ibrahim; Nurlena Andalia; Aiza Rafsanjani
JURNAL HURRIAH: Jurnal Evaluasi Pendidikan dan Penelitian Vol. 6 No. 4 (2025): Jurnal Hurriah: Journal of Educational Evaluation and Research
Publisher : Yayasan Pendidikan dan Kemanusiaan Hurriah Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56806/jh.v6i4.318

Abstract

The students' critical thinking skills are less than optimal in science learning. This study aims to develop and produce a MERDEKA flow teaching module based on outdoor learning to improve critical thinking skills in science learning in grade VII of SMP 2 Darul Hikmah, Aceh Jaya Regency. This objective is based on the results of the analysis, which shows that students' critical thinking skills are not optimal in science learning. This study uses the Research and Development (R&D) ADDIE model method with three stages, namely Analysis, Design, and Development. The analysis stage is carried out to identify students' needs and problems faced in science learning. The design stage involves planning a learning module that integrates outdoor learning activities with the MERDEKA flow. Module development is carried out by designing interactive and interesting materials and activities. The results of the study concluded that the use of the MERDEKA flow teaching module based on outdoor learning is effective in improving critical thinking skills in science learning in grade VII of SMP 2 Darul Hikmah, Aceh Jaya Regency. This can be seen from the average N Gain score of 0.806498609 with a very effective category
Application Of Practicum-Based Project Based Learning To Improve Science Literacy And Student Participation In Elementary School: A Pre-Experimental Study on Ecosystem Learning in Grade V Students Nurlena Andalia; Sri Ardiani; Evi Apriana; Ibrahim Ibrahim; Masyudi Masyudi
JURNAL HURRIAH: Jurnal Evaluasi Pendidikan dan Penelitian Vol. 7 No. 2 (2026): Jurnal Hurriah: Journal of Educational Evaluation and Research
Publisher : Yayasan Pendidikan dan Kemanusiaan Hurriah Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56806/jh.v7i2.426

Abstract

Science learning in elementary schools is often dominated by conventional methods, resulting in low science literacy and limited student participation. This study aims to examine the effectiveness of practicum-based Project Based Learning in improving science literacy and student participation. A quantitative approach with a one-group pretest–posttest design was employed involving 34 fifth-grade students. Data were collected through science literacy tests and observation sheets of student participation. The results showed a significant improvement in students’ science literacy, with the average score increasing from 68.41 to 86.76 and an N-Gain score of 0.58, categorized as moderate. In addition, student participation improved as reflected in increased engagement during discussions, experiments, and project activities. These findings indicate that practicum-based Project Based Learning provides meaningful learning experiences and effectively enhances both science literacy and student participation.
Efektivitas Gel Ekstrak Daun Capa (Blumea balsamifera L.) pada Berbagai Konsentrasi terhadap Penyembuhan Luka Insisi pada Tikus Putih (Rattus norvegicus) Galur Wistar Masyudi Masyudi; Ikhwan Adly; Anita Noviyanti; Nurlena Andalia; Putri Hari Bestari; Refirda Refirda; Rika Yusnaini
Journal of Medical Science Vol 7 No 2 (2026): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v7i2.299

Abstract

Incision wounds are acute wounds whose healing can be delayed by infection and prolonged inflammation. Capa leaves (Blumea balsamifera L.) have traditionally been used by the people of South Aceh to treat wounds, but scientific evidence on their effectiveness in gel form and on the most effective concentration remains limited. This study aimed to examine the effect of capa leaf extract gel on incision wound healing and to determine the most effective concentration based on macroscopic evaluation of wound length. This laboratory experimental study, using a one-factor completely randomised design, involved 30 male Wistar rats (Rattus norvegicus) randomly allocated to five groups (n = 6): K0 (gel base), K1, K2, and K3 (2.5%, 5%, and 10% ethanolic capa leaf extract gel), and K4 (1% gentamicin ointment). All animals received a 3-cm dorsal incision extending to the subcutaneous tissue, and 100 mg of the test preparation was applied twice daily. Wound length was measured daily with a caliper. By design, three animals per group were observed until day 7 and then terminated for tissue sampling, while the remaining three were observed until day 14. Data were analysed descriptively (mean ± standard deviation and percentage of wound shrinkage) and with the Kruskal–Wallis test. On day 7, the mean wound length in K2 (1.80 ± 0.19 cm) and K3 (1.82 ± 0.16 cm) was shorter than in K0 (2.12 ± 0.19 cm), K1 (2.15 ± 0.27 cm), and K4 (2.07 ± 0.28 cm) (Kruskal–Wallis p = 0.020), but no pairwise comparison remained significant after Bonferroni correction. On day 14 (n = 3 per group), the mean wound length in K2 was 0.07 ± 0.12 cm (97.8% shrinkage), followed by K1 (0.50 ± 0.44 cm), K3 (0.80 ± 0.70 cm), K0 (1.03 ± 0.50 cm), and K4 (1.37 ± 0.49 cm); this difference was not statistically significant (p = 0.108). Complete closure occurred in two of three K2 animals and in one animal each in K1 and K3, all on day 14. The 5% capa leaf extract gel showed a tendency towards the fastest wound healing among the groups tested, but this finding is preliminary and does not establish superiority over the gel base or 1% gentamicin ointment. Further studies with larger numbers of animals, assessment of inflammatory signs, histological examination, and measurement of interleukin-2 (IL-2) levels are needed to confirm these findings.
Co-Authors Abdullah Agnes Agnes Aisyah Aisyah Aiza Rafsanjani Armi Armi Azwir Bukhari Usman Cut Morina Zubainur Dian Aswita, Dian Djufri Elvitriana Evi Apriana Evi Apriana Ibrahim Ibrahim Ikhwan Adly Irma Yunita Jailani Jailani Jailani Jalaluddin Jalaluddin Juli Firmansyah Lukmanul Hakim Lukmanul Hakim M. Ridhwan M. Ridhwan Masyudi Masyudi Muhammad Ridhwan Noviyanti, Anita Nurma Nurma Putri Hari Bestari R.M Bambang Rahmadani Refirda Refirda Ridhwan, M. Rika Yusnaini Roslina Roslina Roslina Sri Ardiani Susanti Djakfar T. Iskandar Shah