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All Journal The Avicenna Medical Journal Prosiding Seminar Kesehatan Nasional Sexophone Jurnal Inovasi Pangan dan Gizi
Agustianti, Erika
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Sistematik Literatur Review : Hubungan Stres Terhadap Gangguan Muskuloskletal Pada Pekerja Agustianti, Erika
Prosiding Seminar Kesehatan Nasional Sexophone 2024: Kekerasan dalam Pacaran: Hubungan Romantis Berujung Tragis
Publisher : Universitas Negeri Malang

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Abstract

"The work environment and individual work can cause musculoskeletal disorders. These disorders occur in body structures such as muscles, joints, tendons, ligaments, nerves, bones, and the local blood circulation system. In Indonesia, the prevalence of musculoskeletal diseases has reached 7.9% (Riskesdas, 2018). Stress and musculoskeletal disorders are the main causes of work-related illnesses. This study aims to determine the relationship between stress and musculoskeletal disorders in workers using a systematic literature review method. Secondary data originating from PubMed were utilized, employing the keywords 'MSDs', 'Work Stress', and 'worker' with "AND" as the Boolean operator. Nine articles meeting the inclusion and exclusion criteria were identified. The results of the literature review reveal a high prevalence of musculoskeletal disorders in various work sectors. These disorders are multifactorial, with work stress being a significant factor. The research findings clearly establish a relationship between work stress and musculoskeletal disorders. Recognizing risk factors for musculoskeletal disorders and identifying factors that cause work stress in workers are crucial steps for prevention. This can be achieved through regular evaluation of fatigue and psychological counseling for each worker, providing opportunities for workers to participate in education and training programs, and supporting communication between workers and management to actively resolve worker conflicts."
The relationship between conflict with doctors and lack of experience with Death and dying and the level of occupational stress experienced by nurses at Haji Hospital UIN Syarif Hidayatullah Jakarta Agustianti, Erika; Srisantyorini, Triana; Fauziyah, Munaya; Purnamawati, Dewi; Djauharoh, Siti Nur Aisyah
The Avicenna Medical Journal Vol 5, No 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.45001

Abstract

Background and Purpose: This study investigates the relationship between conflict with doctors, lack of experience with Death and dying, and the level of occupational stress among nurses at Haji Hospital UIN Syarif Hidayatullah Jakarta. The aim is to identify contributing factors to workplace stress and inform interventions to improve nurses' well-being and the quality of healthcare services.Methods: A cross-sectional analytical study was conducted involving all 96 nurses at Haji Hospital UIN Syarif Hidayatullah Jakarta. Data was collected using Expanded Nursing Stress Scale (ENSS) to asses hazard psychosocial and Workplace Stress Scale (WSS) to evaluate occupational stress levels through a Google Form. The study examined the association between conflict with doctors and lack of experience with Death and dying (independent variables) and the nurses' reported stress levels (dependent variable).Results: The study revealed a significant association between conflict with doctors and occupational stress (p=0.000), with nurses experiencing conflict being 6.13 times more likely to experience occupational stress (95% CI: 2.337-16.106). A significant relationship was also found between limited experience with Death and dying and occupational stress (p=0.017), with nurses having limited experience facing a 2.07-fold increased risk of occupational stress (95% CI: 1.188-3.612).Conclusion: The occupational stress experienced by nurses at Haji Hospital UIN Syarif Hidayatullah Jakarta is significantly related to conflict with doctors and limited experience in managing Death and dying situations.  
Bioactive proteins in breast milk and their impact on infant gut development Hermawati, Luluk; Irawati, Nur Bebi Ulfah; Zulfa, Hilizza Awalina; Fidusia, Amanah Eva; Agustianti, Erika; Husna, Firda Asma’ul
Jurnal Inovasi Pangan dan Gizi Vol. 2 No. 2: (August) 2025
Publisher : Institute for Advanced Science, Social, and Sustainable Future

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61511/jipagi.v2i2.2147

Abstract

Background: During early stages of life, breast milk is the mainstay of nutrition. Beyond delivering vital amino acids, certain proteins like lactoferrin, α-lactalbumin, sIgA, and lysozyme bolster the infant's gastrointestinal system and provide protective mucosal factors alongside immunomodulatory functions, helping shape the gut microbiome. The goal of this review is to analyze the scientific literature on the types and composition of proteins in breast milk, their biological functions, and their effects regarding the development and protection of the infant’s gastrointestinal tract with special focus on the mechanisms of mucosal immunity, mucosal defense, and microbial colonization. Methods: A literature search was conducted through PubMed, and Google Scholar databases with the terms bioactive, breastmilk, gut, infant, and microbiota. Only articles published between 2015 and 2025 were chosen for their relevance to the topic and methodological soundness. Findings: Whey proteins, which dominate the early lactation phase, contain bioactive peptides that are easily absorbed and support enterocyte maturation. Lactoferrin and sIgA contribute to maintaining mucosal integrity and preventing pathogen colonization. Growth factors such as epidermal growth factor (EGF) and transforming growth factor-beta (TGF-β) accelerate epithelial maturation and strengthen tight junctions, while other proteins like osteopontin and beta-casein help shape a favorable microbial ecosystem. Conclusion: Breast milk proteins contribute multifaceted roles in gastrointestinal and immune system development, underscoring the importance of exclusive breastfeeding as a foundation for neonatal gastrointestinal and immunological health. Novelty/Originality of this article: This review provides a comprehensive synthesis of the diverse roles of breast milk proteins in shaping infant gastrointestinal development and mucosal immunity by emphasizing perspectives that integrate evidence focused on nutrition, immunology, and the microbiome in a way that has not been fully addressed in previous literature.
Co-Authors Dewi Purnamawati Djauharoh, Siti Nur Aisyah Fauziyah, Munaya Fidusia, Amanah Eva Husna, Firda Asma’ul Irawati, Nur Bebi Ulfah Luluk Hermawati Srisantyorini, Triana Zulfa, Hilizza Awalina