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The effect of katuk leaf (Sauropus androgynous L. merr) extract administration on reducing blood triglyceride levels in male local rabbits induced with hypercholesterolemia Khalid, Idham; Ferasyi, Teuku Reza; Sugito, Sugito; Hafizsha, Nabila Latifa; Ulfa, Rasyida; Fitriana, Rizky; Makmur, Ali
The International Journal of Tropical Veterinary and Biomedical Research Vol 9, No 2 (2024): Vol. 9 (2) November 2024
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/ijtvbr.v9i2.44322

Abstract

This research aimed to study the effectiveness of katuk leaf extract in lowering blood triglyceride levels in male local rabbits treated with hypercholesterolemia. The research was done at the Laboratory of Veterinary Public Health and the Animal Experimental Unit of the Faculty of Veterinary Medicine, Universitas Syiah Kual. This experiment used the Split Plot design, comprising two factors. The first factor was treatment (P1, P2, and P3) that gives katuk leaf extract 2.5 cc, 5 cc, and 10 cc, whereas the second factor was the sampling time (I, II, III, IV, and V). The results of this research showed that the treatment did not significantly (P0.05) on levels of triglycerides in the blood of local rabbits. Still, different sampling times were very significant (P 0.01) on levels of triglycerides in the blood of local rabbits. After doing Duncan tests, the results test showed that the sampling time between a decrease of local rabbit blood triglyceride levels was not significant (P0.05) by giving katuk leaf extract. The treatment of katuk leaf extracts of 2.5 cc, 5cc, and 10cc has not been able to reduce levels of triglycerides in the blood of male local rabbits treated with hypercholesterolemia.
Screening of Bioactive Compounds of Gambir leaf (Uncaria gambir Roxb) as Antibiofilm Againts the Glucosyltransferase of Streptococus mutans Enzyme Khalid, Idham; Sari, Dea Kurnia; Bakri, Muttaqien; Daniel, Daniel; Frengki, Frengki; Makmur, Ali; Riandi, Lian Varis; Ferdian, Riyan; Amiruddin, Amiruddin
Jurnal Medika Veterinaria Vol 18, No 2 (2024): J. Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v18i2.43265

Abstract

The use of natural ingredients in dental care, such as manginang which has become part of the Minang community culture, is considered an alternative dental care that must be created to overcome the negative impacts of dental care made from artificial materials. The core of this study is to change the manginang tradition towards logical verification through screening of bioactive compounds of gambir leaves (Uncaria gambir Roxb.) as antibiofilms against Streptococcus mutans. This study was conducted using an in silico strategy approach with the help of computer programs such as MOE v.09 and Chimera 1.13.1, as well as the Way2Drug site, protein information bank, and protox_ii. This study began with the collection of ligand information from the writing, followed by transformation into 2D and 3D designs. Other antibiofilm actions were decided using the QSAR procedure through the website (http://www.way2drug.com/PASSOnline/predict.php). The selected antibiofilm compounds were then followed by observing their affinity for the receptor (pdb id. 3AIB) using an atomic docking strategy. Finally, the ligand damage profile was observed to anticipate. The results of this study indicate that of the 41 identified gambir leaf compounds, there are 20 compounds that have the potential to have antibiofilm effects with quinnic acid having the highest score (Pa 0.703), while the compound with the strongest affinity for the receptor is chlorogenic acid with an affinity score (Gbinding) of -16.03 kcal/mol and an average of low toxicity (level IV-VI). However, of the 20 bioactive compounds of gambir leaves, only 5 compounds are predicted to have the same potential as the -maltose control.
PENINGKATAN KETRAMPILAN MAHASISWA DALAM PENGELOLAAN SAMPAH ORGANIK DAN KOTORAN TERNAK UNTUK MEWUJUDKAN GREEN CAMPUS DI KAMPUS PSDKU KABUPATEN GAYO LUES Makmur, Ali; Ulfa, Rasyida; Sari, Rahayu Eka; Pani, Mario; Ridhana, Fita; Ilham, Ilham; khalid, Idham; Riandi, Lian Varis; Alkautsar, Alkautsar; Jalaluddin, Muhammad; Novita, Andi
Peternakan Abdi Masyarakat (PETAMAS) Vol 5, No 1 (2025): Volume 5, Nomor 1, Juni 2025
Publisher : Departemen of Animal Science, Agriculture Faculty, Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/petamas.v5i1.44761

Abstract

AbstractThe activity of managing organic waste as a manifestation of achieving a Green Campus is one of the efforts to create a better environment that can benefit the community, especially those living near the campus area. Effective Microorganisms (EM-4) is a mixture of beneficial microorganisms used to improve soil quality, accelerate waste decomposition, reduce environmental pollution, and enhance plant growth. Many plants on campus have suboptimal growth, requiring fertilization. Therefore, it is necessary to engage the campus community, especially students, to produce organic fertilizer by utilizing waste from the campus environment, cafeteria, as well as organic leaf and pine litter waste, so it can be used as compost. More than 95,24% of respondents have never participated in training on compost production. Further training is needed to ensure the target audience better understands waste management.Kegiatan pengelolaan sampah organik merupakan perwujudan untuk menuju Green Campus merupakan salah satu kegiatan untuk mewujudkan terciptanya lingkungan yang baik dan dapat dimanfaatkan bagi masyarakat terutama masyarakat yang dekat dengan areal kampus.Effective Microorganisms (EM-4) adalah campuran mikroorganisme yang bermanfaat yang digunakan untuk meningkatkan kualitas tanah mempercepat penguraian sampah, mengurangi polusi lingkungan dan meningkatkan pertumbuhan tanaman Banyak tanaman yang ada dikampus yang kurang optimal pertumbuhan sehingga perlu pemupukan. Untuk itu perlu mengajak masyarakat kampus khususnya mahasiswa untuk membuat pupuk organik dengan memanfaatkan sampah yang ada di lingkungan kampus atau kantin, kotoran ternak dan sampah organik daun kayu dan seresah pinus sehingga dapat dimanfaatkan sebagai pupuk kompos. Lebih 95,24% responden yang tidak pernah mengikuti dalam pelatihan tentang pembuatan kompos. Perlu pelatihan lebih lanjut sehingga sasaran lebih paham terhadap pengelolaan sampah tersebut.