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DEVELOPMENT OF A BIO-MEMS CANTILEVER-BASED BIOSENSOR FOR THE RAPID, LABEL-FREE DETECTION OF THE AVIAN INFLUENZA VIRUS Rocha, Thiago; Mendes, Clara; Lima, Rafaela
Journal of Biomedical and Techno Nanomaterials Vol. 2 No. 6 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v2i6.2979

Abstract

Avian influenza virus remains a significant threat to global public health, poultry industries, and food security due to its high transmissibility and zoonotic potential. Rapid and reliable detection is essential for early outbreak control, yet conventional diagnostic methods are often time-consuming, laboratory-dependent, and rely on labeled reagents, limiting their applicability in field and point-of-care settings. This study aims to develop a Bio-MEMS cantilever-based biosensor capable of rapid, label-free detection of the avian influenza virus with high sensitivity and specificity. An experimental Bio-MEMS approach was employed, involving microfabrication of silicon cantilevers, surface biofunctionalization with virus-specific recognition elements, and real-time mechanical sensing of virus–receptor interactions. The biosensor’s performance was evaluated by measuring cantilever deflection responses under controlled exposure to varying viral concentrations. The results demonstrate stable baseline behavior, low noise levels, and clear concentration-dependent deflection signals, achieving rapid detection within minutes and a low limit of detection without signal amplification. Non-target analytes produced negligible responses, confirming high specificity. In conclusion, the developed Bio-MEMS cantilever-based biosensor provides an effective platform for rapid, label-free detection of avian influenza virus. This technology shows strong potential for integration into portable diagnostic systems and could be adapted for surveillance of other viral pathogens.
Reinterpreting ‘Khalifah Fil Ard’ as an Islamic Environmental Ethic for Addressing the 21st-Century Climate Crisis Silva, Pedro; Souza, Felipe; Lima, Rafaela; Ummah, Andrian Khoirul
Journal of Humanities Research Sustainability Vol. 2 No. 6 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jhrs.v2i6.2786

Abstract

Background. The accelerating climate crisis has prompted renewed global interest in ethical frameworks capable of guiding sustainable human–environment relations. In Islamic thought, the Qur’anic concept of khal?fah f?l-ar? (vicegerency on Earth) has traditionally been interpreted as a moral mandate for stewardship, accountability, and balanced interaction with the natural world. Purpose. This study aims to reexamine khal?fah f?l-ar? through an interdisciplinary lens that integrates Qur’anic exegesis, environmental philosophy, and climate ethics. Method. A qualitative research design is employed using textual hermeneutics, thematic content analysis of classical and modern tafsir, and comparative ethical analysis with environmental stewardship models. Results. The findings demonstrate that khal?fah f?l-ar? embodies a tripartite ethical structure: spiritual responsibility to God, moral responsibility to creation, and intergenerational responsibility for ecological continuity. These dimensions provide a normative foundation that contrasts sharply with anthropocentric paradigms driving ecological degradation. The research further shows that classical Islamic sources contain implicit ecological principles—such as moderation (wasatiyyah), balance (m?z?n), prohibition of harm (l? ?arar), and communal trust (am?nah)—which can form an integrated ethical framework for climate action. Conclusion. The study concludes that reinterpretation of khal?fah f?l-ar? offers a theologically grounded, ethically robust, and culturally resonant model for addressing climate crisis in Muslim-majority societies and globally. This work highlights the potential of Islamic environmental ethics to contribute meaningfully to sustainable policy, ecological education, and faith-informed climate activism.