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Potential Pharmaceutical Biotechnology Products in the Form of Formulations and Preparations of Telang Flower Kombucha Dish Soap (Clitoria ternatea L) as an Antibacterial from Beef (Bos taurus) Isolate Rezaldi, Firman; Nurvadilah, Eva; Junaedi, Candra; Somantri, Ucu Wandi; Fadillah, M. Fariz; Maritha, Vevi; Yenny, Ratna Fitry; Setyaji, Diyan Yunanto
Journal of Health and Nutrition Research Vol. 3 No. 1 (2024)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v3i1.237

Abstract

This research aims to see the potential of each formulation and preparation of dishwashing soap with the active ingredient telang flower kombucha in inhibiting the growth of pathogenic bacteria isolated from beef. This research is a laboratory experiment, namely by making a dishwashing soap base without the active substance of telang flower kombucha. Make a dishwashing soap base that adds the active substance of butterfly pea flower kombucha at concentrations of 20%, 30% and 40%. Biochemical identification results have shown that beef samples contain gram-positive bacteria in the form of Staphylococcus aureus and Listeria monocytogenes, as well as gram-negative bacteria in the form of Salmonella thyposa and Escherichia coli. The results of this research have also proven that pharmaceutical biotechnology products in the form of formulations and dishwashing soap preparations with the active ingredient telang flower kombucha have a positive correlation in inhibiting the growth of the four test bacteria. Based on the one-way ANOVA statistical test at each P value <0.05, it proves that telang flower kombucha dish soap at a concentration of 40% according to post hoc analysis is not significantly different from concentrations of 20% and 30% as a pharmaceutical and antibacterial biotechnology product. isolated from beef. The conclusion of this research is that the formulation and preparation of dishwashing soap at a concentration of 40% proved to be the most effective as a pharmaceutical biotechnology product in inhibiting the growth of the four test bacteria.
AKTIVITAS ANTIOKSIDAN PADA SEDIAAN KOMBUCHA BUNGA TELANG YANG DIRACIK DARI FORMULASI GULA AREN DAN MADU SR12 SEBAGAI PRODUK BIOTEKNOLOGI PANGAN DAN FARMASI Rezaldi, Firman; Utami, Arti Wahyu; Resti Wijayanti, Fitria Eka; Purbanova, Reni; Wati, Dyah Rohma; Suminar, Erny; Kusumiyati, Kusumiyati; Mu’jijah, Mu’jijah; Faizah, Nai’matul Retno; Cahyono, Andri Tri; Setyaji, Diyan Yunanto; Fadillah, M Fariz; Yenny, Ratna Fitry
AGRIBIOS Vol 22 No 2 (2024): November
Publisher : Program Studi Agribisnis Fakultas Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/agribios.v22i2.5209

Abstract

The food and pharmaceutical fields are two elements needed in everyday life to improve human health and well-being. This is because functional foods, medicines, and natural cosmetics have become an increasingly current trend to be applied both based on food biotechnology and pharmaceutical biotechnology. One of the food and pharmaceutical biotechnology products that can be effective as a source of antioxidants is the butterfly pea flower kombucha preparation. Butterfly pea flower kombucha preparations that are effective as a source of antioxidants certainly have a substrate formula that varies based on the results of their concoctions. The results of previous studies have proven that butterfly pea flower kombucha with a concentration of palm sugar and SR12 honey has activity as a source of antibacterial. Research to see the antioxidant activity that is formulated based on various formulations of palm sugar and SR12 honey substrates. The stages of this research include making butterfly pea flower kombucha with various concentrations of palm sugar and SR12 honey substrates and testing its antioxidant activity on each preparation formulated from the palm sugar and SR12 honey substrate formulation (20%, 30%, and 40%). One-way analysis of variance was applied, followed by post-hoc analysis. Based on the post-hoc analysis, the study showed that butterfly pea flower kombucha at a concentration of 40%, as well as the formula of palm sugar and SR12 honey, showed significant differences from the concentrations of 20% and 30% after testing one-way analysis of variance, with each P value <0.05. The conclusion is that the preparation of butterfly pea flower kombucha based on the use of palm sugar and SR12 honey substrates is efficacious as a source of antioxidants so that in the long term it can be used as a functional food ingredient or pharmaceutical.
The Relationship Between Fried Food Consumption, Alcohol Consumption, and Nutritional Knowledge of "Isi Piringku Model T" with the Incidence of Overweight in 19-44 years Adult in Indonesia Yudhayanti, Titik; Setyaji, Diyan Yunanto
Journal of Global Nutrition Vol 4 No 1 (2024)
Publisher : Ikatan Sarjana Gizi Indonesia (ISAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53823/jgn.v4i1.85

Abstract

The prevalence of overweight in Indonesia increased very quickly from 8.6% in 2007 to 11.5% in 2013, and increased to 13.6% in 2018. This research aims to determine the relationship between fried food consumption patterns and consumption patterns. alcohol, and nutritional knowledge of "Isi Piringku Model T" with the incidence of overweight at the age of 19-44 years in Indonesia. Respondents in this study numbered 581 from all over Indonesia and were aged 19-44 years. The sampling technique was non-random sampling technique with consecutive sampling method. This research uses a cross sectional research design. The data collection instrument uses a questionnaire via Google Form. Data were analyzed using descriptive statistical analysis and Chi Square test. The results showed that the type and frequency of fried food consumption, status, frequency, amount of alcohol consumption, and nutritional knowledge of "Isi Piringku Model T" showed a relationship that was not statistically significant (p>0.05). Based on the research results, it can be concluded that there is no significant relationship between consumption of fried foods, alcohol consumption, nutritional knowledge of "Isi Piringku Model T" and the incidence of overweight in adults aged 19-44 years in Indonesia.
The Effect of Family Support in Nutrition Education on Dietary Adherence and Blood Glucose Levels of Type 2 Diabetes Mellitus Inpatients at Panti Rapih Hospital Yogyakarta Setyaning Jati, Yacinta Adies; Setyaji, Diyan Yunanto; Purnawijayanti, Hiasinta Anatasia
Journal of Global Nutrition Vol 4 No 2 (2024)
Publisher : Ikatan Sarjana Gizi Indonesia (ISAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53823/jgn.v4i2.94

Abstract

Diabetes mellitus is included in the group of metabolic diseases with characteristics of hyperglycemia that occurs due to abnormalities in insulin secretion and function or both. According to the Association of Diabetes Care and Education Specialists, there are 7 pillars of diabetes mellitus management that can be done, one of which is providing nutritional education. The purpose of this study was to determine an effect of family support in nutritional education on dietary compliance and blood glucose levels of type 2 diabetes mellitus at Panti Rapih Hospital, Yogyakarta. This study used a quantitative research design with a quasy experiment design with an accidental sampling method with a sample size of 34 diabetes mellitus inpatients divided into control and experimental groups. The variables of this study will be analyzed using SPSS, with the T-Paired Test and T-Independent Sample Test. Based on the statistical results, the effect of education on dietary compliance in the control and experimental groups showed a p value of 0.000 <0.05. While the statistical results of the effect of education on blood glucose levels in the control group showed a p value of 0.002 <0.05, in the experimental group the results of the p value were 0.001 <0.05. However, based on the results of the statistical test on the difference in compliance scores, a p value of 0.000 <0.05 was obtained. While the results of the statistical test of blood glucose levels obtained a p value of 0.315> 0.05. It can be concluded that family support in providing nutritional education can influence the increase in compliance scores for following a diet but does not affect blood glucose levels in type 2 diabetes mellitus patients at Panti Rapih Hospital, Yogyakarta.
The Relationship Between Protein and Iodine Intake and The Incidence of Stunting in Toddlers Aged 12-24 Months at The Srumbung Health Center, Magelang Regency Sulistyani, Theresia Deby; Setyaji, Diyan Yunanto; Purnawijayanti, Hiasinta Anatasia
Journal of Global Nutrition Vol 4 No 2 (2024)
Publisher : Ikatan Sarjana Gizi Indonesia (ISAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53823/jgn.v4i2.95

Abstract

Stunting is a condition of growth failure in toddlers due to chronic malnutrition, especially in the first 1000 days of life, namely from when the child is in the womb until the age of 24 months. Toddlers are said to be stunted if their height per age is <-2 SD. The purpose of this study was to determine the relationship between protein intake and iodine intake with the incidence of stunting in toddlers aged 12-24 months at the Srumbung Health Center, Magelang. This study used a cross-sectional research design with a sample size of 100 toddlers aged 12-24 months at the Srumbung Health Center. Based on the results of the study, it was stated that the better the daily protein intake of toddlers in the last 3 months, the lower the risk of toddlers aged 12-24 months at the Srumbung Health Center experiencing stunting. From this study, it can be concluded that the incidence of stunting in toddlers aged 12-24 months in the Srumbung Health Center area is related to protein intake but not to iodine intake.
Standardized Nutrition Care Process for Critically Ill Patients with Traumatic Brain Injury, Pulmonary Contusion, and Alcohol Intoxication Setyaji, Diyan Yunanto; Suryani, Isti; Lestari, Nugraheni Tri; Iskandar, Slamet; Mayasari, Meike
Journal of Global Nutrition Vol 5 No 2 (2025)
Publisher : Ikatan Sarjana Gizi Indonesia (ISAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53823/jgn.v5i2.113

Abstract

Disturbed intake factors, hypermetabolism and hypercatabolism in critical patients cause increased energy needs. Critical patients are very susceptible to nutritional deficiencies resulting in decreased immune systems, poor wound healing, and organ failure that prolongs hospitalization and increases mortality. In these circumstances, nutrition becomes an important part of clinical medical therapy. This study was conducted to implement nutritional services and standardized nutritional care processes in patients with a medical diagnosis of Decreased Consciousness e.c. Severe Head Injury e.c. Traumatic Intracerebral Haemorrhage (TICH), Traumatic Subarachnoid Haemorrhage (TSAH), Intraventricular Haemorrhage (IVH), Pulmonary Contusion, Right Antebrachial Trauma, Close Fracture Ulna 1/3 Distal Right, Alcohol Intoxication, Brainstem Contusion in the Gatotkaca Ward 4 MICU Dr. Sardjito General Hospital. This study uses a descriptive qualitative research design with a case study design. This study used primary and secondary data with data presentation in narrative, tabular, and graphical form. Based on NRS 2002 screening, the patient was at risk of malnutrition. The food intake graph for six days with a high energy and protein diet in the form of enteral per NGT or parenteral diet showed fluctuations in intake from 8.30% on the first day to 33.78% on the sixth day. Acceptance of the NGT diet decreased since the third day as indicated by low absorption and gastric residue. The results of the blood gas analysis showed that the patient had respiratory acidosis. It can be concluded that the standardized nutritional care process and collaboration between health professionals that are carried out optimally and intensively cannot always provide a good prognosis in cases of severe head injury with various complications such as alcohol intoxication, pulmonary contusion, and brainstem contusion.