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All Journal Jurnal Biologi Tropis Jurnal Kesehatan Tambusai Jurnal Pepadu SALUT: Journal of Social and Education
Attaya, Kalisa
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STUDI PEMANFAATAN ANTIBODI MONOKLONAL SEBAGAI TERAPI DAN DIAGNOSIS PADA PASIEN : ARTIKEL REVIEW Yuningsih, Rizma Kurniawati; Attaya, Kalisa; Yustitia, Nur Tahany; Maziya, Raehanul; Utari, Widi Gustita; Listyacahyani, Anggit
Jurnal Kesehatan Tambusai Vol. 6 No. 2 (2025): JUNI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i2.45406

Abstract

Antibodi monoklonal adalah protein yang diproduksi dari satu klon sel dan diklasifikasikan ke dalam empat jenis: murine, chimeric, humanized, dan antibodi manusia. Artikel ini bertujuan untuk meninjau pemanfaatan antibodi monoklonal dalam terapi dan diagnosis berbagai penyakit. Metode yang digunakan adalah Systematic Literature Review dari 13 artikel ilmiah yang diperoleh melalui database seperti PubMed, Google Scholar, dan ScienceDirect. Hasil studi menunjukkan bahwa antibodi monoklonal efektif dalam mendiagnosis penyakit menular (seperti MERS-CoV, TBC, malaria, zika, schistosomiasis) dan tidak menular (seperti penyakit Parkinson dan Alzheimer), dengan memanfaatkan interaksi spesifik antara antibodi-antigen melalui teknik seperti ELISA dan imunokromatografi. Sebagai terapi, antibodi ini digunakan untuk menangani berbagai penyakit seperti Alzheimer, asma, migrain vestibular, sepsis, HIV-1, rheumatoid arthritis, dan penyakit mata. Beberapa antibodi bekerja dengan mengikat target seperti amiloid, IL-13, CGRP, atau TNF-α untuk memodulasi respons imun dan mengurangi gejala penyakit. Efektivitas dan spesifisitas tinggi dari antibodi monoklonal menjadikannya alat penting dalam bidang kedokteran modern, baik dalam mendiagnosis secara akurat maupun memberikan terapi yang ditargetkan dengan efek samping minimal.
PEMBUATAN COOKIES DAUN MANGROVE (Rhizophora mucronata) DALAM UPAYA OPTIMALISASI PEMANFAATAN TANAMAN MANGROVE Attaya, Kalisa; Maziya, Raehanul; Amalia, Marshanda Fitri; Bulkis, Nanda; Sutanti, Baiq Novia Rahmadita; Permatasari, Lina
Jurnal Pepadu Vol 6 No 1 (2025): Jurnal Pepadu
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v6i1.6150

Abstract

An unhealthy lifestyle can lead to increased production of free radicals as a byproduct of metabolism. This condition can be mitigated by antioxidants. Rhizophora mucronata offers various health benefits, including its role as an antioxidant. However, public utilization of Rhizophora mucronata remains limited. To enhance its appeal, Rhizophora mucronata was processed into mangrove leaf cookies, making it more convenient for consumption. The objective of this activity was to optimize the utilization of mangrove plants. The activity was conducted on December 20, 2024, at the Meninting Village Hall, Batulayar Subdistrict, West Lombok Regency, with 20 participants. The implementation method included training sessions comprising the delivery of materials on mangrove plants and the process of making mangrove cookies, followed by hands-on cookie-making training. The participants were highly enthusiastic throughout the program, and the material was well understood, as evidenced by the quiz results provided during the session.
Literature Review: Extraction Methods and Antioxidant Activity of Rhizophora mucronata Leaves Attaya, Kalisa; Saputri, Legis Ocktaviana; Permatasari, Lina
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8949

Abstract

Free radicals are highly reactive molecules and can trigger various degenerative diseases, so prevention efforts are needed through effective antioxidants. This study aims to review and analyze the extraction method of R. mucronata leaves in increasing antioxidant activity against DPPH free radicals. This study was conducted through a literature review of experimental research articles obtained from Google Scholar and PubMed databases using specific keywords, covering national and international publications for the period 2015-2025. The obtained articles were analyzed based on the extraction technique, solvent type, and IC₅₀ value reported in the article. The analysis showed that cold extraction methods, especially multi-step maceration with methanol solvent, can produce R. mucronata leaf extracts with very strong antioxidant activity with an IC₅₀ value of 0.04 ppm. The conclusion of this study confirms that extraction technique and solvent selection can affect the antioxidant activity of R. mucronata leaves. These findings support the need for optimization of extraction methods to maximize antioxidant effectiveness in the development of natural antioxidants.
Urgensi Pendidikan Pancasila Untuk Mencegah Radikalisme Arzy, Muhammad Dimas; Marasabessy, Keysha Nabilla Putri; Salsabila, Ghina; Attaya, Kalisa; Nuralyza, Imasayu; Nugrahani, Baiq Dwiyan; Dalila, Virga Fathiya
Journal of Social and Education Vol. 2 No. 1 (2025): Journal of Social and Education
Publisher : Lembaga Riset dan Publikasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/3mhseg82

Abstract

Radikalisme merupakan tantangan besar bagi persatuan Indonesia karena tidak sejalan dengan prinsip-prinsip Pancasila. Pendidikan Pancasila dianggap sebagai elemen kunci dalam menangkal paham radikal, khususnya di kalangan pemuda. Studi ini bertujuan untuk menganalisis pentingnya memperkuat pendidikan Pancasila sebagai upaya pencegahan radikalisme di dunia pendidikan dan masyarakat. Beberapa manfaat penelitian ini antara lain: meningkatkan kesadaran akan perlunya penguatan ideologi nasional, menjadi pedoman dalam menyusun kurikulum pendidikan berbasis karakter, serta mempromosikan kolaborasi antar-pemangku kepentingan untuk melawan radikalisme. Metode penelitian yang digunakan adalah studi literatur dengan menganalisis sumber-sumber akademis terpercaya dari jurnal ilmiah dalam kurun waktu sepuluh tahun terakhir. Temuan penelitian mengungkap bahwa strategi efektif untuk memperkuat ketahanan ideologi pemuda dan mencegah radikalisme meliputi: penanaman nilai Pancasila sejak dini, optimalisasi media digital, penyatuan nilai-nilai Pancasila dalam kurikulum, serta pendekatan multikultural dan kerja sama lintas sektor.
Co-Authors Amalia, Marshanda Fitri Arzy, Muhammad Dimas Bulkis, Nanda Dalila, Virga Fathiya Listyacahyani, Anggit Marasabessy, Keysha Nabilla Putri Maziya, Raehanul Nugrahani, Baiq Dwiyan Nuralyza, Imasayu Ocktaviana Saputri, Legis Permatasari, Lina Salsabila, Ghina Sutanti, Baiq Novia Rahmadita Utari, Widi Gustita Yuningsih, Rizma Kurniawati Yustitia, Nur Tahany