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Cardiac Disease in Pregnancy: Maternal and Perinatal Outcomes in RSUP Dr. Mohammad Hoesin Palembang Ni Made Dyah Gayatri; Peby Maulina Lestari; Abarham Martadiansyah; Nuswil Bernolian; Hadrians Kesuma Putra; Rizky Agustria; Muwarni Emasrissa Latifah
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 2 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i2.448

Background: Impaired maternal and uteroplacental perfusion can occur in pregnancy with cardiac disease leading to maternal and perinatal mortality and morbidity due to increased cardiac load and ventricular dysfunction. This research aims to determine maternal and perinatal outcomes of pregnancies with cardiac disease. Method: This research was a descriptive observational study conducted by total sampling method and cross-sectional design. This research used medical records of pregnant women with cardiac disease who gave birth in RSUP Dr. Mohammad Hoesin Palembang in January 2018-December 2020 as study samples. Result: Among 68 pregnancies with cardiac disease, there were 6 cases (0.87%) found in 2018, 38 cases (2.47%) found in 2019, and 24 cases (1.48%) found in 2020. The highest distribution of pregnancies with cardiac disease was found at 64.7% in the range of 20-35 years old age group; 57.4% in the multiparity group; 38.2% in the range of ≥34 – <37 weeks gestational age group; 86.8% in the high school educational level group; 66.2% in the high-risk cardiac functional status group; 54.4% in the peripartum cardiomyopathy group; and 36.8% with preeclampsia/eclampsia as a comorbid. In this study, maternal outcomes found were maternal mortality at 11.8%; cardiac failure at 70.6%; arrhythmia at 1.5%; and stroke at 1.5%, while perinatal outcomes found were prematurity at 60.3%; low birth weight at 64.4%; IUGR at 37.0%; IUFD at 1.4%; stillbirth at 6.8%; neonatal death at 9.6%; and perinatal asphyxia at 42.5%. Conclusion: The prevalence rate of pregnancies with cardiac disease in RSUP Dr. Mohammad Hoesin Palembang was 0.87% in 2018, 2.47% in 2019, and 1.48% in 2020. The most common maternal outcome in this study was cardiac failure, with most in the peripartum cardiomyopathy group, while the most common perinatal outcome was low birth weight, with most in the hypertensive heart disease group.

Risk Factors of Vesicovaginalis Fistule in Obstetric and Gynecologic Division of Dr. Mohammad Hoesin General Hospital in 2018-2020 Nabila Istighfarin; Hadrians Kesuma Putra; Eka Handayani Oktharina; Ratih Krisna; Septi Purnamasari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 3 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i3.476

Background. A vesicovaginal fistula (FVV) is a direct pathological connection between the bladder and vagina resulting in uncontrolled leakage of urine into the vagina from the bladder. Based on the cause, fistulas are divided into two, namely obstetric fistula and gynecological fistula. The risk factors that influence the occurrence of FFV consist of obstetric risk factors (age, parity, delivery method, duration of delivery, birth weight) and gynecological risk factors (history of gynecological surgery, history of pelvic radiotherapy, history of gynecologic malignancy). The purpose of this study was to determine the relationship between risk factors and the incidence of vesicovaginal fistula. Methods. This research is an observational-analytic study with a cross-sectional method. The number of samples obtained was 74 patients who met the inclusion criteria using secondary data from medical records. Analysis of the data used is the chi-square test. Results. There were 37 people who experienced vesicovaginal fistula. Where there were 9 patients with obstetric vesicovaginal fistula (24.3%) and 28 people (75.7%). From the Chi-Square test analysis, there was a significant relationship between delivery method (p=0.029), birth weight (p=0.029), history of gynecological surgery (p=0.038), history of pelvic radiotherapy (p=0.016), history of gynecological malignancy (p=0.016). =0.010). Meanwhile, there was no significant relationship between age (p=0,347), parity (p=1,000), and duration of labor (p=0,082). Conclusion. There was a significant relationship between the delivery method, birth weight, history of gynecological surgery, history of pelvic radiotherapy, history of gynecological malignancy. There was no significant relationship between age, parity, and duration of vaginal delivery.

Diagnosis and Management of Vesicouterine Fistula (Youssef’s Syndrome): A Case Report Amir Fauzi; Ratih Krisna; Hadrians Kesuma Putra; Sonia Prima Arisa Putri; Febi Stevi Aryani; Hana Andrina
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 5 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i5.501

Background. Vesicouterine fistula (VUF) is a rare pathological communication between the uterus or cervix and the bladder. Youssef's syndrome is an atypical presentation of a patient with a vesicouterine fistula, characterized by a triad of cyclic hematuria, amenorrhea, and absence of urinary incontinence. Because of this atypical presentation, the patient may go undiagnosed and patient management will be delayed. Case presentation. A 39-year-old woman complained of hematuria. The patient underwent a second caesarean section in 2008 and a few weeks after the procedure the patient complained of leakage of urine from her vagina. Six months later the patient complained hematuria on her menstrual cycle and amenorrhea, with absence of urinary incontinence. Ultrasound examination found adhesions between the uterus and vagina, and irregular bladder mucosa. Patient underwent cystoscopy with endometriosis were suspected on vesicovaginal repair scars and a bladder biopsy was also performed with the results of no endometrial stroma and glands then followed by hysteroscopy. Hysteroscopy result showed a 20 mm diameter hole with irregular margins. Subsequently, the patient was treated with hysterorrhaphy laparotomy and fistula repair. Conclusion. One type of vesicouterine fistula is Youssef's syndrome, which is a complication following a lower segment caesarean section with undiagnosed bladder injury. The diagnosis can be confirmed by cystoscopy, intravenous pyelography, hysterosalpingogram, sonography, and other types of imaging tests. Management of patients with VUF can be conservative, medical, or surgical.

Korelasi Vitamin D terhadap Kadar Antimullerian Hormone pada Pasien Sindroma Ovarium Polikistik dengan Obesitas di Kota Palembang Usman, Fatimah; Putra, Hadrians Kesuma; Abadi, A; Siahaan, Salmon Charles
Jurnal Ilmu Kedokteran Vol 18, No 2 (2024): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v18i2.2024.108-112

Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine system disorders affecting women of reproductive age. One of the biomarkers for the diagnosis of PCOS is Anti Mullerian Hormone (AMH). Meanwhile, women with PCOS are at higher risk for vitamin D deficiency. The research aims to examine vitamin D and AMH for PCOS women with obesity. PCOS or also known as hyperandrogenic anovulation (HA), or Stein-Leventhal syndrome, is one of the most common endocrine system disorders affecting women of reproductive age. This study was analytic with a cross-sectional approach. The subjects were women with PCOS who went to Dr. M. Hoesin Sriwijaya University (n=30). Inclusion criteria were patients diagnosed with PCOS using Rotterdam, patients who had not received therapy for insulin resistance, and were obese. The exclusion criteria were that the patient couldn’t fulfill Rotterdam criteria and/or option not to participate in this study. The results were that most patients experienced oligomenorrhea (76.7%), the age mean was 31.17 years, and the BMI mean was 33.4 kg/m2. The Spearman correlation test showed a negative correlation between AMH and Vitamin D (p=0.011, correlation coefficient=-0.458). There was no correlation between BMI and vitamin D in PCOS patients, but there was a negative correlation between AMH and vitamin D levels.

Prevalence and Distribution of Risk Factors for Preterm Labor in RSUP DR. Mohammad Hoesin Palembang Period January 1 2020 – December 31 2023 Beumaputra, Adyatma Utama; Martadiansyah, Abarham; Nurwany, Raissa; Mirani, Putri; Putra, Hadrians Kesuma
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 1 Maret 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i1.825

Objective: This study aims to determine the prevalence and distribution of risk factors for preterm labor.Methods: This is a descriptive observational study with a cross-sectional design. The data used in this study were secondary data obtained with the total sampling method from the medical records of Dr. Mohammad Hoesin Palembang Hospital from January 1, 2020 to December 31, 2023.Results: This study found 1,654 cases of preterm labor from January 1, 2020 to December 31, 2023. The analysis of risk factors among mothers indicated that those within the high-risk age categories (<20 years and >35 years) constituted 31.7%. Multiparous and grand multiparous women represented 41.7%, while multiple pregnancies accounted for 6.6%. A history of premature rupture of membranes was noted in 25.4% of cases, polyhydramnios was observed in 1.3%, and a history of cesarean delivery was found in 25.4%. Furthermore, 33% suffered from hypertension, and 2.5% had diabetes. Anemia was prevalent in 47.9% of the mothers, and infection was reported in 42.8%. A history of preterm delivery was noted in 13.7%, risky gestational distance was found in 10.6%, and 25% had a history of antepartum hemorrhage. Finally, obesity was observed in 14.5% of the mothers.Conclusion: The number of deliveries continued to decrease, but the prevalence of preterm labor increased from 2020 to 2023. Anemia is the most common risk factor found in mothers with preterm labor.Prevalensi dan Distribusi Faktor Risiko Persalinan Prematur di RSUP Dr. Mohammad Hoesin Palembang dalam Tiga TahunAbstrakTujuan: Penelitian ini bertujuan untuk mengetahui prevalensi serta distribusi faktor risiko persalinan prematur.Metode: Penelitian ini merupakan penelitian deskriptif observasional dengan desain cross-sectional. Data yang digunakan dalam penelitian ini merupakan data sekunder dengan metode total sampling dari data rekam medik RSUP Dr. Mohammad Hoesin Palembang periode 1 Januari 2020 – 31 Desember 2023.Hasil: Terdapat 1654 kasus persalinan prematur dengan periode 1 Januari 2020 – 31 Desember 2023. Distribusi faktor risiko didapatkan ibu dengan usia berisiko (<20 tahun dan >35) tahun (31,7%), paritas multipara dan grandemultipara (41,7%), kehamilan multipel (6,6%), riwayat ketuban pecah dini (25,4%), polihidramnion (1,3%), riwayat persalinan sesar (25,4%), hipertensi (33%), diabetes (2,5%), anemia (47,9%), infeksi (42,8%), riwayat persalinan prematur (13,7%), jarak kehamilan berisiko (10,6%), riwayat perdarahan antepartum (25%), obesitas (14,5%). Kesimpulan: Jumlah persalinan terus mengalami penurunan, namun prevalensi kejadian persalinan prematur terus mengalami peningkatan dari tahun 2020-2023. Anemia menjadi faktor risiko paling banyak yang ditemukan pada ibu dengan persalinan prematur.Kata kunci: Prevalensi, Persalinan Prematur, Faktor Risiko

Prevalence and Characteristics of Pregnant Women With Urinary Incontinence at Rika Amalia Hospital Palembang Juenli, Angelica; Fauzi, Amir; Putra, Hadrians Kesuma; Krisna, Ratih; Nurwany, Raissa
Biomedical Journal of Indonesia Vol. 11 No. 2 (2025): Vol 11, No 2, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v11i2.224

Introduction. Urinary incontinence (UI) is the involuntary discharge of urine. UI is often not reported due to social stigma and public relief. In addition, UI is a non-life-threatening condition so people consider UI as a nuisance and not a health problem. This shows the need for promotive and preventive efforts so that patients can immediately seek medical treatment and prevent UI. This study aims to identify the prevalence and characteristics of pregnant women with UI at Rika Amalia Hospital Palembang. Methods. This study is an observational descriptive research with a cross-sectional research design using primary data by filling out questionnaires and direct interviews with pregnant women at Rika Amalia Hospital Palembang. Results. This study involved 73 pregnant women. Most UI cases were at the age of <35 years (88%), education level ≤12 years (68%), no smoking behavior (100%), no caffeinated beverage consumption behavior (96%), third trimester (60%), multipara (40%), vaginal delivery (56%), BMI ≥ 25 kg/m2 (56%), no history of constipation (60%), no history of UI before pregnancy (92%), and had no family history of UI (88%). Conclusion. The prevalence of pregnant women with UI at Rika Amalia Hospital Palembang from August to October 2024 is 34.2%. Most UI cases happened in pregnant women with the age of <35 years, education level ≤12 years, no smoking behavior, no caffeinated beverage consumption behavior, third trimester, multipara, vaginal delivery, BMI ≥ 25 kg/m2, no history of constipation, no history of UI before pregnancy, and no family history of UI.

Characteristics of Endometriosis Patients in Dr. Mohammad Hoesin General Hospital on 2018 to 2020 Leriva, Ratu Tenny; Iskandar Zulqarnain; Hadrians Kesuma Putra; Awan Nurtjahyo; Syifa Alkaf
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 4 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i4.478

Background. Endometriosis is defined as the presence of endometrial-like tissue outside the uterus. The prevalence of endometriosis is not known with certainty because it is necessary to perform a laparoscopy to confirm the diagnosis of endometriosis and is usually found during examination for other indications. This study aims to explore the characteristics of endometriosis patients at Dr. Mohammad Hoesin General Hospital Palembang. Methods. This research is descriptive observational research. The research data were obtained from the medical records of endometriosis patients treated at Dr. Mohammad Hoesin General Hospital Palembang from 2018 to 2020. Results. Of the 105 sample data studied, the most distribution of endometriosis patients was in the reproductive age group (15-49 years) (99%), menarche 12-14 years (67.6%), the location of endometriosis in the ovaries (58.1%), status indoor workers (99%), marital status (85.7%), fertile (43.8%), and infertile patients (41.9%), the chief complaint of dysmenorrhea (66.7%), stage IV disease (63, 8%), nullipara (60%), surgical management (79%). Conclusion. Most of the characteristics of endometriosis patients were in the reproductive age group (15 – 49 years), menarche 12-14 years, endometriosis location in the ovary, indoor worker status, marital status, infertility, the main complaint of dysmenorrhea, stage IV disease, nullipara, surgical treatment.

Characteristics of Endometriosis Patients in Dr. Mohammad Hoesin General Hospital on 2018 to 2020 Leriva, Ratu Tenny; Iskandar Zulqarnain; Hadrians Kesuma Putra; Awan Nurtjahyo; Syifa Alkaf
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 4 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i4.478

Background. Endometriosis is defined as the presence of endometrial-like tissue outside the uterus. The prevalence of endometriosis is not known with certainty because it is necessary to perform a laparoscopy to confirm the diagnosis of endometriosis and is usually found during examination for other indications. This study aims to explore the characteristics of endometriosis patients at Dr. Mohammad Hoesin General Hospital Palembang. Methods. This research is descriptive observational research. The research data were obtained from the medical records of endometriosis patients treated at Dr. Mohammad Hoesin General Hospital Palembang from 2018 to 2020. Results. Of the 105 sample data studied, the most distribution of endometriosis patients was in the reproductive age group (15-49 years) (99%), menarche 12-14 years (67.6%), the location of endometriosis in the ovaries (58.1%), status indoor workers (99%), marital status (85.7%), fertile (43.8%), and infertile patients (41.9%), the chief complaint of dysmenorrhea (66.7%), stage IV disease (63, 8%), nullipara (60%), surgical management (79%). Conclusion. Most of the characteristics of endometriosis patients were in the reproductive age group (15 – 49 years), menarche 12-14 years, endometriosis location in the ovary, indoor worker status, marital status, infertility, the main complaint of dysmenorrhea, stage IV disease, nullipara, surgical treatment.

Correlation of Vitamin D and Antimullerian Hormone Level in Infertile Women with Polycystic Ovary Syndrome and Obesity Usman, Fatimah; Saleh, Irsan; Effendi, Kms. Yusuf; Putra, Hadrians Kesuma; Abadi, Adnan; Siahaan, Salmon Charles Pardomuan Tua; Kesty, Cindy; Rizda, Dian Permata; Stevanny, Bella; Lestari, Peby Maulina
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 3 November 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i3.723

Introduction: Increasing amount of research indicates that women with PCOS are more likely to have a shortage in vitamin D with abnormally high anti-Müllerian hormone (AMH) levels. This study aims to assess the correlation between vitamin D and Anti-Mullerian Hormone (AMH) levels in infertile women with polycystic ovarian syndrome (PCOS) and obesity. Method: This observational cross-sectional study examined all obese women with PCOS who sought infertility treatment at Dr. Mohammad Hoesin Hospital Palembang from August 2021 to November 2021. PCOS diagnosis was determined using the Rotterdam criteria. All research subjects underwent a physical examination and transvaginal ultrasound to evaluate body mass index (BMI) and polycystic ovary morphology. Blood samples were collected to evaluate their testosterone, AMH, and vitamin D levels. Statistical analysis was performed using the Spearman correlation test with IBM® SPSS Statistics version 24. Results: Thirty infertile women with PCOS and obesity were included in the study, with average age of 31.17±4.48 years and average BMI of 33.45±2.67 kg/m2. The majority of the subjects had polycystic ovary morphology (86.7%) and oligomenorrhea (76.7%). No correlation between BMI and vitamin D as well as AMH levels was found in infertile women with PCOS and obesity. The Spearman test showed moderate negative correlation (p = 0.011. r = -0.458) between vitamin D and AMH levels in infertile women with PCOS and obesity. Conclusion: There is a moderate negative correlation between vitamin D and AMH levels among infertile women with PCOS and obesity. Further research is required to comprehend the role of vitamin D in female fertility.Korelasi Vitamin D dan Kadar Hormon Anti-Müllerian pada Wanita Infertil dengan Sindrom Ovarium Polikistik dan ObesitasAbstrakPendahuluan: Semakin banyak penelitian melaporkan bahwa wanita dengan PCOS cenderung mengalami defisiensi vitamin D dengan penignkatan kadar hormon anti-Müllerian (AMH). Penelitian ini bertujuan untuk mengkaji hubungan vitamin D dan kadar AMH pada wanita infertil dengan sindrom ovarium polikistik (SOPK) dan obesitas.Metode: Penelitian ini merupakan studi observasional potong lintang terhadap seluruh wanita infertil dengan SPOK dan obesitas yang di RSUP Dr. Mohammad Hoesin Palembang pada bulan Agustus 2021 hingga November 2021. Diagnosis SOPK ditegakkan berdasarkan kriteria Rotterdam. Seluruh subjek penelitian menjalani pemeriksaan fisik dan ultrasonografi transvaginal untuk menilai indeks massa tubuh (IMT) dan morfologi ovarium polikistik. Sampel darah dikumpulkan dari semua wanita untuk mengukur kadar testosteron, AMH, dan vitamin D. Analisis statistik dilakukan dengan menggunakan uji korelasi Spearman menggunakan IBM® SPSS Statistics versi 24.Hasil: Tiga puluh wanita infertil dengan SOPK dan obesitas dilibatkan dalam penelitian ini dengan usia rata-rata 31,17±4,48 tahun dan rata-rata IMT 33,45±2,67 kg/m2. Mayoritas subjek memiliki morfologi ovarium polikistik (86,7%) dan oligomenore (76,7%). Tidak ada korelasi antara IMT dan vitamin D maupun kadar AMH pada wanita infertil dengan SOPK dan obesitas. Uji Spearman menunjukkan korelasi negatif sedang (p=0.011.r=-0.458) antara kadar vitamin D dan AMH pada wanita infertil dengan SOPK dan obesitas. Kesimpulan: Kadar vitamin D berkorelasi negatif dengan kadar AMH pada wanita infertil dengan SOPK dan obesitas. Penelitian lebih lanjut diperlukan untuk memahami peran vitamin D pada kesuburan wanita.Kata kunci: Anti-Müllerian Hormone, Indeks Massa Tubuh, Obesitas, Sindrom Ovarium Polikistik, Vitamin D

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