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All Journal Jurnal Kedokteran Syiah Kuala Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Administrasi Kesehatan Indonesia Jurnal Sinaps Majalah Kedokteran Neurosains Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Britain International of Exact Sciences Journal (BIoEx Journal) Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh Indonesian Journal of Case Reports Neurona Media Penelitian dan Pengembangan Kesehatan Jurnal Kolaborasi Akademika
Dian Lestari, Nova
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HUBUNGAN INTENSITAS NYERI PUNGGUNG BAWAH UNILATERAL DENGAN DERAJAT OSTEOARTRITIS DAN INTENSITAS NYERI LUTUT KONTRALATERAL DI RUMAH SAKIT UMUM DAERAH DR. ZAINOEL ABIDIN BANDA ACEH Riska Santi Putri; Dessy Rakhmawati Emril; Syamsul Rizal; Nova Dian Lestari; Yopie Afriandi Habibie
Jurnal Sinaps Vol. 5 No. 2 (2022): Volume 5 Nomor 2, Juni 2022
Publisher : Neurologi Manado

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Abstract

Introduction: Low back pain (LBP) is one of the most common forms of musculoskeletal pain and is often encountered in everyday life. LBP can interfere with a person's work performance so that it can reduce human productivity. The pain caused by LBP can radiate to the ipsilateral leg and cause the contralateral leg to withstaand more weight due to the inability of the ipsilateral leg. This condition can also cause osteoarthritis (OA) in the contralateral leg of patients with LBP. Aims: This study aims to analyze the relationship between unilateral lower back pain and the degree of contralteral knee osteoarthritis at Dr. Zainoel Abidin Banda Aceh. Methods: This study was an observational analytic study with a cross-sectional design. The sample in this study was taken using the total sampling method. Based on the inclusion and exclusion criteria, 17 people can be analyzed. Data collection was carried out by collecting medical records in neurological clinics and radiology installations.Results: The results of this study indicate that 50% of respondents showed a degree of pain on a scale of 5 (moderate category), 40% of respondents indicated the degree of knee OA grade 2 and grade 3. Based on the results of the analysis with the Spearman test, it was found that there was a relationship between unilateral low back pain intensity and the degree OA of the contralateral knee (p value = 0.026) and based on the results of the analysis with the Spearman test, it was also found that there was a relationship between the intensity of unilateral low back pain and the intensity of contralateral knee pain (p value = 0.047). Discussion: The conclusion of this study is that there is a relationship between unilateral low back pain with the degree of osteoarthritis and the intensity of contralteral knee pain in Dr. General Hospital. Zainoel Abidin Banda Aceh.
Gambaran Fungsi Kognitif Pra Lanjut Usia di Pos Binaan Terpadu Puskesmas Kopelma Darussalam Kota Banda Aceh Nova Dian Lestari; Rayya Az-Zahra; Dessy Rakhmawati Emril; Nirwana Lazuardi Sary; Suherman
Jurnal Sinaps Vol. 6 No. 1 (2023): Volume 6 Nomor 1, Februari 2023
Publisher : Neurologi Manado

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Abstract

Populasi lansia yang terus meningkat memberikan manfaat jika lansia tersebut sehat, tangguh dan kuat. Deteksi dini terkait penurunan fungsi kognitif pada masa pra lansia sangat diperlukan sehingga upaya menghambat progresivitas gangguan segera dilakukan untuk menjaga kapasitas fungsional pada masa lansia. Tujuan penelitian adalah untuk mengetahui gambaran fungsi kognitif dan domain kognitif pada kelompok pra lanjut usia. Jenis penelitian adalah deskriptif. Sampel dipilih dengan metode non-probability sampling dengan teknik total sampling dan didapatkan 60 subjek. Penelitian dilakukan di Pos Binaan Terpadu (Posbindu) Puskesmas Kopelma Darussalam yang mencakup 5 desa. Instrumen yang digunakan dalam penelitian ini adalah MoCA-Ina dan pengambilan data dilakukan secara wawancara. Hasil penelitian menunjukkan 55% kelompok pra lanjut usia memiliki fungsi kognitif yang tidak normal dan 45% normal. Domain yang menurun pada subjek tidak normal adalah memori tertunda (97%), fungsi eksekutif (93,9%), atensi (78,8%), bahasa (75,8%), dan visuospasial (48,5%). Sedangkan domain yang menurun pada subjek normal adalah memori tertunda (88,9%), bahasa (44,4%), fungsi eksekutif (40,7%), atensi (22,2%), dan visuospasial (14,8%). Kesimpulan penelitian ini adalah terjadi penurunan fungsi kognitif pada kelompok pra lansia di Posbindu Puskesmas Kopelma Darussalam yang didominasi dengan penurunan pada domain memori.
Prevalence of Epilepsy in Dr. Zainoel Abidin Hospital Banda Aceh Nova Dian Lestari
Jurnal Kedokteran Syiah Kuala JKS Edisi Khusus Oktober 2022
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v0i0.29645

Abstract

Background Studies investigating the prevalence and incidence of epilepsy are increasingly common, particularly in low- and middle-income countries. Prevalence is expectedly lowest early in life, increasing to its highest level during adolescence and early adulthood, decreases after age 30, and remains fairly constant for the remainder of life.2 The prevalence of the disease tends to increase with age, with a peak at 20–29 years and a subsequent decrease, with a ratio of 7.17 (95% CI 4.67– 11.01) in individuals aged 60 years or older. Higher rates can be found when the prevalence is calculated in the context of a prospective survey. In the Rotterdam study that included individuals aged 55 years or older, the overall prevalence of active epilepsy was 9 per 1,000, with an increase with age from 7 per 1,000 for people aged 55– 64 years to 12 per 1,000 for those aged 85–94 years. Sex, while not commonly thought to affect the occurrence of epilepsy, may contribute to differences in epilepsy incidence. The incidence of epilepsy tended to be higher in males than females. Some suggest that females may be more likely to conceal their epilepsy diagnosis if they live in a country where they would be considered unmarriageable or socially marginalized.3,4
HEMICHOREA/HEMIBALISMUS DENGAN HIPERGLIKEMIA NONKETOTIK PADA STROKE ISKEMIK AKUT Safridawat Safridawat; Hidayaturrahmi Hidayaturrahmi; Natasya Wanda; Nova Dian Lestari; Syahrul Syahrul
NEURONA Vol 37 No 2 (2020)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v37i2.117

Abstract

HEMICHOREA/HEMIBALLISM ASSOCIATED WITH NONKETOTIC HYPERGLYCEMIC ON ACUTE ISCHEMIC STROKEABSTRACTHemichorea/hemiballism (HCHB) associated with nonketotic hyperglycemia in acute ischemic stroke is a well-recognized syndrome characterized by the sudden occurrence of hemichorea or more severe expression like hemiballism. The hyperkinetic movements involve the face, arm, or leg. HCHB in acute ischemic stroke is a movement disorder that is rarely reported with hyperkinetic movement. This case report aimed to describe patient with HCHB associated with hyperglycemia as prior sign of stroke ischemic and propose a possible pathophysiology. We report three patients who had HCHB accompanied by hemiparesis, facial and hypoglossus nerve palsy. Laboratory results showed increased serum glucose levels and negative urine ketones. Imaging findings of head CT scan found an infarction in the basal ganglia. Patients are treated with antiplatelet and or anticoagulant therapy and correction of hyperglycemia with additional therapy of dopamine receptor antagonistThe combination of a recent or old striatal lesion and hyperglycemia induce HCHB, causing increased inhibition of the subthalamic nucleus and causing decreased GABAergic inhibition of the thalamus. Diabetes mellitus should always be suspected in patients who develop HCHB movements. When hyperglycemia is detected and treated, movement disorders resolve within a few days and the administration of dopamine receptor antagonists can be considered.Keywords: Hemiballism, hemichorea, hyperglycemia, ischemic strokeABSTRAKHemichorea/hemibalismus (HCHB) yang  berhubungan  dengan  hiperglikemia nonketotik pada stroke iskemik akut adalah sindrom yang ditandai oleh munculnya  hemichorea yang terjadi secara tiba-tiba atau disertai dengan gejala yang lebih berat, seperti   hemibalismus. Pergerakan hiperkinetik meliputi wajah, lengan dan tungkai. HCHB pada stroke iskemik akut merupakan gangguan pergerakan hiperkinetik yang jarang dilaporkan. Laporan kasus ini bertujuan untuk menggambarkan pasien yang mengalami keluhan HCHB sebagai gejala awal terjadinya stroke iskemik disertai dengan hiperglikemia dan memperkirakan  penjelasan patofisiologi yang mungkin terjadi pada pasien ini. Kami melaporkan tiga pasien dengan keluhan HCHB sebagai gejala awal stroke iskemik akut yang disertai hiperglikemia. Pada ketiga kasus tersebut keluhan disertai dengan paresis nervus fasialis, hipoglossus serta hemiparesis ekstremitas kontralateral lesi. Kadar glukosa serum meningkat dan keton urin negatif. Gambaran CT scan menunjukkan adanya infark di ganglia basalis. Pada tata laksana kami menemukan bahwa koreksi hiperglikemi disertai pemberian terapi antikoagulan dan atau antiplatelet serta agen neuroleptik dapat menyebabkan perbaikan luaran pada gejala HCHB secara perlahan. Kombinasi lesi striatal baru dan hiperglikemia dapat menginduksi terjadinya HCHB karena kedua hal tersebut dapat menyebabkan peningkatan inhibisi inti subtalamik dan gangguan  inhibisi GABAergic talamus. Diabetes melitus harus selalu dicurigai pada pasien dengan keluhan HCHB. Ketika hiperglikemia terdeteksi dan ditatalaksana, gangguan  gerakan menghilang dalam beberapa hari dan dapat dipertimbangkan dengan pemberian terapi neuroleptik.Kata kunci: Hemibalismus, hemichorea, hiperglikemia, stroke iskemik
Enhancing Early Detection of Alzheimer's Disease through MRI using Explainable Artificial Intelligence Noviandy, Teuku Rizky; Idroes, Ghifari Maulana; Purnawarman, Adi; Imran, Imran; Lestari, Nova Dian; Hastuti, Sri; Idroes, Rinaldi
Indonesian Journal of Case Reports Vol. 2 No. 2 (2024): December 2024
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v2i2.255

Abstract

Alzheimer’s disease is a progressive brain disorder that causes memory loss and cognitive decline, affecting millions of people worldwide. Early detection is critical for slowing the disease's progression and improving patient outcomes. Magnetic Resonance Imaging (MRI) is widely used to identify brain changes associated with AD, but subtle abnormalities in the early stages are often difficult to detect using traditional methods. In this study, we used a deep learning approach with a model called ResNet-50 to analyze MRI scans and classify patients into four categories: Non-Demented, Very Mild Demented, Mild Demented, and Moderate Demented. The model was trained using MRI images, achieving an accuracy of 95.63%, with strong sensitivity, precision, and specificity. To make the model’s predictions understandable for healthcare professionals, we applied a technique called Grad-CAM, which highlights areas of the brain that influenced the model’s decisions. These visual explanations help clinicians see and trust the reasoning behind the AI's results. While the model performed well overall, misclassifications between adjacent disease stages were observed, likely due to class imbalance and subtle brain changes. This study demonstrates that explainable AI tools can improve early detection of Alzheimer’s disease, supporting clinicians in making accurate and timely diagnoses. Future work will focus on expanding the dataset and combining MRI with other clinical information to enhance the tool's reliability in real-world settings.
Analisis Gambaran Elektroensefalografi (EEG) Pada Pasien Penyakit Ginjal Kronik di RSUD dr. Zainoel Abidin Banda Aceh Lestari, Nova Dian Lestari; Astini, Nur; Amra, Khusnul
Journal of Medical Science Vol 5 No 2 (2024): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v5i2.141

Abstract

Penyakit ginjal kronik masih menjadi masalah kesehatan masyarakat di seluruh dunia. Penyakit ginjal kronik sebagai kondisi umum yang dikaitkan dengan peningkatan risiko disfungsi organ multipel salah satunya dapat menyebabkan kerusakan otak dan bermanifestasi sebagai uremik ensefalopati. Diagnosis dini ensefalopati uremik merupakan hal yang sulit, patofisiologinya masih belum jelas, sangat kompleks dan bersifat multifaktorial. Kelainan gambaran elektroensefalografi telah diketahui sebagai salah satu tanda klinis pada penyakit ginjal kronik. Penelitian ini bertujuan untuk mengetahui analisis gambaran elektroensefalografi pada pasien penyakit ginjal kronik di Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh. Jenis penelitian yang digunakan dalam penelitian ini adalah termasuk jenis penelitian observasional analitik dengan rancangan cross sectional. Populasi target penelitian ini adalah semua pasien penyakit ginjal kronik yang dirawat di ruang rawat penyakit dalam RSUDZA selama periode penelitian dilakukan. Sampel penelitian ini adalah pasien penyakit ginjal kronik yang dirawat di ruang rawat penyakit dalam RSUDZA yang memenuhi kriteria inklusi sebanyak 30 sampel yang telah dipilih dengan menggunakan teknik consecutive sampling. Analisis data dilakukan dengan analisis univariat untuk menyajikan frekuensi dan persentase dari keseluruhan sampel penelitian. Data juga dianalisis bivariat menggunakan uji chi square untuk melihat hubungan antar masing-masing variabel. Hasil penelitian menunjukkan bahwa terdapat hubungan antara stadium penyakit ginjal kronik dengan gambaran EEG dengan presentase gambaran EEG abnormal sebesar 53,3% dimana 3,3% pada penyakit ginjal kronik stadium 3, 30% pada stadium 4 dan 20% pada stadium 5.
Hubungan Lama Pengobatan Dan Jenis Obat Antiepilepsi Dengan Efek Samping Obat Pada Pasien Epilepsi Di Poliklinik Neurologi RSUDZA Nova Dian Lestari; Sri Hastuti; Nur Astini
Journal of Medical Science Vol 3 No 2 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v3i2.98

Abstract

Epilepsy is one of the most common neurological diseases that can affect people of all ages, races, social classes, and geographic locations. Epilepsy is caused by abnormal release of neurons in the brain characterized by seizures. Data from the World Health Organization shows that epilepsy accounts for a significant proportion of the world's disease burden, affecting nearly 50 million people worldwide. The goal of management of epilepsy patients is to control seizures and improve quality of life. However, the side effects of antiepileptic drugs can significantly impair quality of life. This study aims to determine the relationship between duration of treatment and types of antiepileptic drugs with side effects of drugs in epilepsy patients at RSUDZA Neurology outpatient clinic. This is an observational analytic study with a cross sectional design. The sample of this study was epileptic patients at RSUDZA Neurology Outpatient Clinic based on inclusion and exclusion criteria with a total of 42 samples. Sampling was carried out from May−September 2022 using a consecutive sampling technique and filling out the Liverpool Adverse Effect Profile (LAEP) questionnaire. Existing research sample data were tabulated and analyzed by univariate analysis to present the frequency and percentage. Spearman's correlation statistical test was used to test the relationship between variables.  The patients consisting of 17 men (40.5%) and 25 women (59.5%). The average length of treatment that respondents had undergone was 52 months, all of whom experienced side effects of antiepileptic drugs. The results of the Spearman's correlation statistical test showed that there was no relationship between the length of treatment and the type of antiepileptic drug with drug side effects in patients diagnosed with epilepsy at RSUDZA Neurology Outpatient Clinic.
ATTITUDE-TO-ANXIETY CORRELATION OF EPILEPSY PATIENT CAREGIVERS Ismy, Dewi Purnama Sari; Lestari, Nova Dian; Hastuti, Sri; Suhanda, Rachmad
Media Penelitian dan Pengembangan Kesehatan Vol. 35 No. 3 (2025): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v35i3.3103

Abstract

Epilepsi adalah gangguan neurologis yang ditandai dengan kejang tak terduga, yang tidak hanya memengaruhi kualitas hidup pasien tetapi juga keluarga atau pendampingnya akibat dampak fisik, kognitif, dan psikososial yang ditimbulkan. Pendamping pasien sering mengalami masalah psikologis yang mungkin berkorelasi dengan sikap mereka terhadap epilepsi. Penelitian terdahulu menunjukkan sikap yang positif terkait epilepsi akan memberikan respon kecemasan yang lebih rendah. Penelitian ini bertujuan untuk menganalisis hubungan antara sikap dan kecemasan pada pendamping pasien epilepsi di Poliklinik Saraf RSUD Dr. Zainoel Abidin Banda Aceh selama periode Juni hingga Juli 2024. Merupakan studi analitik observasional dengan desain cross-sectional. Subjek penelitian adalah pendamping pasien epilepsi di RSUD Dr. Zainoel Abidin Banda Aceh yang dipilih dengan pendekatan probability sampling menggunakan metode simple random sampling. Sebanyak 43 subjek memenuhi kriteria penelitian. Sikap pendamping dinilai menggunakan Public Attitude Toward Epilepsy (PATE), sementara tingkat kecemasan dinilai menggunakan Hamilton Anxiety Rating Scale (HARS). Uji korelasi Spearman digunakan untuk menguji sikap pendamping pasien epilepsi dengan kecemasan pendamping pasien epilepsi (p value >0,05). Hasil penelitian mendapatkan mayoritas sikap pendamping pasien epilepsi adalah positif, sedangkan mayoritas tingkat kecemasan yang dialami adalah kecemasan sedang. Pendamping dengan sikap positif lebih cenderung memiliki kecemasan sedang (42,9%). Namun, hubungan antara sikap dan kecemasan tidak signifikan secara statistik (p=0,87, r=-0,026). Penting halnya untuk setiap pendamping pasien epilepsi mendapatkan edukasi yang komprehensif mengenai penyakit, penanganan, dan prognosis yang dapat membantu sikap yang lebih positif dan mengurangi stigma yang dapat memengaruhi sikap pendamping pasien epilepsi.
Pentingnya Edukasi Epilepsi dalam Pendidikan di Sekolah Nova Dian Lestari; Miftahul Jannah
JKA Vol. 2 No. 1 (2025): JKA
Publisher : Bansigom Na Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26811/vqtn6t07

Abstract

Pendidikan tentang epilepsi di sekolah sangat penting untuk menciptakan lingkungan pendidikan inklusif dan meningkatkan pemahaman tentang kondisi neurologis ini di kalangan siswa, guru, dan staf sekolah. Penelitian ini mengkaji tingkat kesadaran dan pemahaman tentang epilepsi serta dampak pendidikan epilepsi dalam menciptakan budaya sekolah yang mendukung. Hasil penelitian menunjukkan bahwa sebelum adanya pelatihan, banyak pendidik yang belum memahami epilepsi sehingga memicu kesalahpahaman dan stigma terhadap siswa penderita epilepsi. Usai sesi edukasi, guru menunjukkan respon yang lebih baik, membantu mengurangi sikap diskriminatif dan memberikan dukungan kepada siswa ketika mengalami penyerangan. Temuan ini menekankan pentingnya penerapan pendidikan epilepsi terstruktur di sekolah untuk menciptakan lingkungan yang lebih aman, inklusif, dan mendukung bagi siswa penderita epilepsi
Pemanfaatan Inovasi Teknologi untuk Pemberdayaan Komunitas dalam Penanganan Epilepsi yang Berkelanjutan : Review Article Lestari, Nova Dian; Fitriani, Dewi
JKA Vol. 2 No. 2 (2025): JKA
Publisher : Bansigom Na Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26811/zhh6wf04

Abstract

Challenges in managing epilepsy arise not only from clinical aspects, but also from social stigma, limited access to diagnostic and therapeutic services, and the general public's lack of understanding. This article explores how technological advancements can be utilized to empower communities in raising awareness and achieving sustainable epilepsy management. Through a descriptive and analytical approach based on global data and field experience, this study discusses various innovations such as digital applications, wearable devices, telemedicine services, e-learning platforms, and Virtual Reality-based therapy. Evidence shows that the use of technology can significantly expand access to healthcare services, enhance the competencies of medical personnel, and reduce stigma. It is concluded that synergy among stakeholders and the contextual adaptation of technology within communities are key strategies for improving the quality of epilepsy care
Co-Authors . Harapan . Syahrul Adi Purnawarman, Adi Ahmad Hamim Sadewa Amra, Khusnul Astini, Nur Dedy Syahrizal Dessy Rakhmawati Emril Dessy Rakhmawati Emril Dessy Rakhmawati Emril DEWI FITRIANI Endang Mutiawati Rahayuningsih* Farida Gunawan Hasan Sjahrir Hidayaturrahmi Hidayaturrahmi Ida Ayu Putu Sri Widnyani Idroes, Ghifari Maulana Imran Imran Imran Imran Imran Irwan Saputra Ismy, Dewi Purnama Sari M. Yogi Riyantama Isjoni Maimun Syukri MIFTAHUL JANNAH Mulyanti Mulyanti Nasrul Musadir Natasya Wanda Nirwana Lazuardi Sary Nur Astini Nurjannah Nurjannah Nurjannah Nurjannah Nurul Fajri Rachmad Suhanda Rayya Az-Zahra Rinaldi Idroes Riska Santi Putri Safridawat Safridawat Solly Aryza Sri Wahyuni Suherman Suherman Syahrul Syahrul Syahrul Syamsul Rizal Teuku Rizky Noviandy Tristia Rinanda Wahyuni, Sri Yoo Soo Ji Yopie Afriandi Habibie