Claim Missing Document
Check
Articles

Found 12 Documents
Search

Formulasi dan Uji Aktivitas Antibakteri Sediaan Gel Anti Jerawat Ekstrak Daun Sirih Gading Lemon (Epipremnum aureum) Terhadap Bakteri Propionibacterium acnes ATCC 6919 Elsa Vernanda Candra Dewi; Septian Maulid Wicahyo; Annie Rahmatillah
An-Najat Vol. 4 No. 3 (2026): Agustus: An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v4i3.3984

Abstract

Acne (acne vulgaris) is a skin condition caused by various factors, one of which is infection by the bacterium Propionibacterium acnes. The leaves of the lemon pothos (Epipremnum aureum) are known to contain secondary metabolites such as flavonoids, alkaloids, saponins, tannins, and triterpenoids that have potential antibacterial properties. This study aims to determine the physical quality of an ethanol leaf extract gel formulation of golden pothos, its antibacterial activity against Propionibacterium acnes ATCC 6919, and to identify the optimal gel concentration for inhibiting the growth of this bacterium. The study showed that all gel formulations met physical quality requirements, including organoleptic properties, homogeneity, pH, viscosity, and spreadability. Phytochemical analysis revealed that the ethanol extract of lemon-leaved betel leaves contains flavonoids, alkaloids, saponins, tannins, and triterpenoids. The average inhibition zone diameters against Propionibacterium acnes were 6.1 mm at 4%, 7.4 mm at 8%, and 9.3 mm at 16%, respectively, while the positive control measured 12.1 mm, and the negative control showed no inhibitory effect. The results of the One-Way ANOVA test showed a significant difference among the treatment groups (p = 0.006).
Analisis Proses Penyimpanan dan Distribusi Obat di Gudang Instalasi Farmasi RSUD Dr Moewardi Nabila Dhea Fitriani; Vivin Marwiyati Rohmana; Annie Rahmatillah
An-Najat Vol. 4 No. 3 (2026): Agustus: An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v4i3.3987

Abstract

The management of medications in hospital pharmacy storage facilities is vital for maintaining the accessibility, integrity, and safety of pharmaceuticals. If the protocols for storage and distribution do not adhere to regulations, it can result in damage, expiration, shortages, or excess inventory. Thus, it is important to assess how medications are stored and distributed within hospital pharmacy storage facilities. The purpose of this research was to examine the practices for the storage and distribution of medications at the pharmacy warehouse of Dr. Moewardi Regional General Hospital (RSUD) and to evaluate the level of compliance with relevant medication management guidelines. A descriptive approach was utilized, incorporating both qualitative and quantitative techniques. Data collection involved observations using checklists, semi-structured discussions with warehouse staff, and reviews of administrative records. The data analysis was descriptive, comparing observed practices in the field against the defined indicators and guidelines for medication management. The evaluation also included checking medication conformity with the National Formulary and categorizing them by usage frequency. The findings revealed that the medication storage procedures comprised 30 indicators, with 29 (96.7%) meeting the required standards and 1 (3.3%) falling short. For the distribution procedures, 15 indicators were assessed: 13 (86.7%) were implemented, and 2 (13.3%) were not. The alignment with the National Formulary was recorded at 92.37%. The classification based on usage rates revealed categories of "fast-moving" and "slow-moving" medications, which need to be monitored for optimal inventory management. In summary, the medication storage and distribution practices at the pharmacy warehouse of Dr. Moewardi RSUD are largely effective and compliant with standards, though certain indicators require enhancement. Ongoing assessment and inventory management are essential to improve the overall efficiency of medication processes.