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The Effect of Motivation on Memory Recall Among the Students of SS 11A and SS 11B of Government Model Secondary School Makurdi Danladi Zakariah; Elvis O. Ihaji; Tensaba Andes Akafa; Gloria Omonefe Oladele; Kingsley Iyoko Iseko; Vika Tensaba Akafa; Izam Emmanuel David; Oche Williams Ujah
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 1 No 2 (2024): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v1i2.3979

Abstract

This study investigated the effect of motivation on memory recall among students of SS11A and SS11B of Government Model Secondary School Makurdi. The study employed the use of experimental design of 3x2x1 One-Way Analysis of Variance (ANOVA) and Independent T test with Alpha level of .05 to test the two hypotheses. The study consists of sixty (60) participants with 30 (50%) males and 30 (50%) females. Their ages ranged from 13-20 years with the means of 8.15 (SD=23.41). The participants were grouped into three of high, low and non-motivated students. Each group had (20) participants each totalling sixty (60) in the study. The participants were selected on the basis of gender and evenly distributed through the use of purposive and convenience sampling techniques. Finding from the study indicated that there was significant different in the level of memory recall among the high, low and non-motivated students F (2, 57) =8.98, P<.05. There was no significant different between male and female students on memory recall when motivated (59) =.20 P>.05. Thus, the first hypothesis was confirmed and the null hypothesis was rejected. On the other hand the second hypothesis was rejected and the null hypothesis was accepted. It was therefore recommended that conscious efforts should be made by the parents, Teachers, School Administrators to provide various incentives to enhance students recall abilities in memory task. It was also recommended that the Government and Philanthropists should provide scholarship programme to enhance study memory recall in the Secondary School. Finally, the study recommended that psychologists and the teachers should encourage the student to always rehearse their work in order to improve their memory recall when the need arise.
Effect of Jatropha Gossypiifolia Leaves in Wistar Albino Rats Against Gentamicin-Induced Biochemical Injury Isaac John Umaru; Tensaba Andes Akafa; Joseph Oteng; Ingwu Joseph Akem; Ocheifa Mathew Ngbede; Ashaka Fidelis Utioukpan; Aboki Nwunuji Mijinyawa; Odok Endurance Akam; Ogholo Ogholo Ekup
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 2 No 2 (2025): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v2i2.5186

Abstract

Jatropha gossypiifolia L. (Euphorbiaceae), widely known as “bellyache bush,” is a medicinal plant largely used throughout Africa and America. Several human and veterinary uses in traditional medicine are described for different parts and preparations based on this plant. The protective potentials of ethanol leaf extract of Bryophyllum pinnatum against gentamicin induced biochemical injury in Wistar albino rats were evaluated using serum biochemical parameters. Twenty-five male albino rats were divided randomly into five groups A to E. Groups C and D received 100, 200 and 300 mg/kg Jatropha gossypiifolia leaves extract respectively. Groups A and B were fed with chow (normal and positive controls) while Group E received 100 mg/kg of Vitamin C. Biochemical injury was induced in rats in groups B-E with gentamicin (i.p) at the dose of 80 mg/kg body weight on the 16th day of study. The rats were then fasted for 48 h and sacrificed by cervical dislocation. Serum was collected for biochemical analysis using standard methods and analytical biochemical kits. There was a significant increase in the serum levels of AST, ALT and ALP of the rats administered with gentamicin (Group B - positive control) compared to the Group A- normal control. However, treatment of rats with 100, 200 and 300 mg/kg body weight of ethanol leaf extract of Jatropha gossypiifolia L significantly decrease these biochemical parameters compared to Group B (p < 0.05). Also, there was a significant increase in the serum levels of conjugated bilirubin and total bilirubin in Group B compared to the normal control. Rat pre-treated with 200 and 300 mg/kg body weight of extract showed significant decrease in the conjugated and total bilirubin compared to the non-treated rats in Group B (p <0.05). Serum level of urea and creatinine significantly increased in Group B compared to normal control. Rats in groups C and D pre-treated with 200 and 300 mg/kg body weight of extract showed significant decrease in the levels of urea and creatinine compared to Group B (p <0.05). There was significant decrease in the serum levels of albumin and total protein of the rats administered with gentamicin compared to the normal control. Rats pre-treated with 200 and 300 mg/kg body weight of extract showed significant increase compared rats in non-treated Group B (p <0.05). The results obtained from this study shows that the ethanolic leaf extract of Jatropha gossypiifolia L has protective functions against gentamicin-induced hepatic and nephrotic damage in Wistar albino rats.
Effect of Administration of Copper plasma Activated water and Anesthetic on Hematological and Pancreatic tissues of Wister rats Isaac John Umaru; Iseko Iyoko Kingsly; Prince Kwadwo Gyasi; Edom Favour Ogochukwu; Tensaba Andes Akafa; Jackson Soyinka Malantso; Bilyaminu Habibu; Kerenhappuch Isaac Umaru
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 1 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i1.4722

Abstract

In biomedicine, applications of PAW span from biofilm removal, wound healing, deactivation of bacteria and viruses, dentistry (for teeth disinfection and whitening), and cancer therapy. The biochemical activity of PAW is derived from synergistic effects of the highly reactive species, specifically reactive oxygen and nitrogen species (RONS). PAW is considered a biofriendly and prospective solution for biotechnology applications due to the time dependent nature of its biochemical activity because of the active species, and its economic and environmental benefits of using air rather than toxic chemicals as the raw material. Thus, the study on Effect of Administration of Copper plasma Activated water and Anaesthetic on Haematological and Pancreatic tissues of Wister rats. Material and Methods: Preparation of plasma-activated water a non-thermal micro-hollow cathode discharge (MHCD) was used to generate plasma-activated waters (CU-PAWs). Results: The results showed the haematological profile of the animals treated with 400mgkg-' had a decrease in Haemoglobin, Mean capsular Haemoglobin (11.21 ± 1.23 and 22.93 ± 21.11) compared to the controlled group (15.03 ± 1.72 and 29.93 ± 7.27) and in animals treated with 200mgkg-1 and 400mgkg-1 there is a significant decrease in the platelets (21.96 ± 23.16 and 20.89 ± 24.03) compared to animals on control group (32.08± 16.70) (table 2). Animals treated with 200mgkg-' and 400mgkg-' have a decrease in platelet (22.36 ± 4.88 and 20.89 ± 24.03) compared to animals on control (32.08 ± 16.70) and also animals treated with 400mgkg-1 have an elevated white blood cell count 173-56 ± 4.50) compared to the control group (3.66 ± 3.06). Conclusion: Cupper plasma water is safe to be used since it do not have much effect on the blood biochemistry and haematological parameters unlike the aesthetic agents cause changes on the haematological and blood biochemistry parameters. Hence, it is important to be aware of the effects of these agents before using them in experiments.
Effect of Aqueous Extract of Achyranthes aspera Leaves on Antiretroviral Drug-Induced Hepatotoxicity in Rats Isaac John Umaru; Mary Athanasius Udoh; Tensaba Andes Akafa; Joseph Oteng; Ingwu Joseph Akem; Ocheifa Mathew Ngbede; Ashaka Fidelis Utioukpan; Aboki Nwunuji Mijinyawa; Ogholo Ogholo Ekup
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5183

Abstract

Achyranthes aspera leaves are believed to reverse drug resistance and increase the efficacy of current drugs. Achyranthes aspera leaves contain many secondary metabolites needed for the redressal of diseases and ailment. Thus, the ART-induced hepatotoxicity in rats. Methodology: Thirty (30) albino rats were divided into 5 groups of 6 each and treated as follows: Group A (no antiretroviral drugs, no extract); group B (antiretroviral drugs alone); group C (extract alone); group D (antiretroviral drug plus 40 mg/kg extract); group E (antiretroviral drug plus 80 mg/kg extract). All treatment lasted for twenty-eight days. Blood samples were collescted and serum ALT and AST determined using UV-spectrophotometer. The mean (± S.E.M) of data were calculated and further analysed for statistical significance using graph Pad Prism 5.0. Results: Mean serum ALT were 36.8 ± 20.24, 56.11 ± 6.12, 54.6 ± 24.18, 90.40 ± 11.14, 88.36 ± 13.10 and that of AST were 143.8 ± 20.24, 208.4 ± 16.13, 60.0 ± 24.18, 164.40 ± 11.14, 52.36 ± 16.14 for groups A, B, C, D, and E respectively. There was a statistically significant difference between the mean values of serum AST for group B and those for group C. However, there was no statistically significant difference between the ALT values for the test and control groups of rats (p value >0.999) Also, there was no statistically significant difference between the mean values of AST for group B and those of groups A, D, E. Conclusions: This extract at a higher concentration should add to the treatment of HIV in synergy with antiviral drugs, However, the extract shown no significant reduction of serum ALT and AST in ART treated rats.
Potential of Aqueous Leaves Extract of Jatropha Gossypiifolia Seed Against Highly Active Antiretroviral Therapy Induced Hepatotoxicity in Rats Isaac John Umaru; Tensaba Andes Akafa; Ingwu Joseph Akem3; Joseph Oteng; Ocheifa Mathew Ngbede; Ashaka Fidelis Utioukpan; Aboki Nwunuji Mijinyawa; Odok Endurance Akam; Ogholo Ogholo Ekup
African Journal of Sciences and Traditional Medicine Vol 2 No 2 (2025): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v2i2.5182

Abstract

While many methods exist for measuring the impact of AIDS, treatment remedy the human development approach focuses on people rather than medical or economic indicators. Human Development Index captures three basic dimensions of human development: a long and healthy life—measured by life expectancy at birth; knowledge—measured by adult literacy and school enrolment; and standard of living—measured by per capita gross domestic product. Thus, investigate the hepatoprotective activity of aqueous extract of Jatropha gossypiifolia seed in highly active antiretroviral therapy administered rats. Liver is a metabolically active organ responsible for many vital life functions. It performs many activities that are critical for survival. Due to its important activities, the liver is exposed to a number of insults and is one of the body's organs most subject to injury. In spite of tremendous advances in modern medicine, there are hardly any reliable drugs that protect the liver from damage and/or help in regeneration of hepatic cell. It is, therefore, necessary to search for effective and safe herbal drugs for the treatment of liver disease to replace currently used drugs of doubtful efficacy and safety. Hence, the need to evaluate the aqueous extract of Jatropha gossypiifolia seed in highly active antiretroviral therapy (Lamivudine, Zidovudine and Efavirenz) administered rats. Sixty rats weighed between 150-200g were randomly divided into six groups and each group comprised of ten rats. Rats in group I were administered with distilled water. Rats in group II were administered with highly active antiretroviral therapy only. Rats in groups III - VI were administered 100, 200, 400 and 600 mg/kg Jatropha gossypiifolia seed plus highly active antiretroviral therapy respectively. The treatments were given orally for 28 consecutive days. On the 29th day, all rats were sacrificed under light diethyl ether anaesthesia; blood samples were collected for the assessment of biochemical parameters, while Serum levels of liver enzymes ALT, AST, ALP, and GGT were significantly (p<0.05) increased and albumin concentration was significantly decreased in animals treated with highly active antiretroviral therapy as compared to the normal control. Treatment of highly active antiretroviral therapy exposed animals with Jatropha gossypiifolia seed showed marked improvement in biochemical findings. Rise in liver enzymes was almost restored to normal in animals treated with Jatropha gossypiifolia seed. Jatropha gossypiifolia seed through its antioxidant activity effectively protects highly active antiretroviral therapy induced liver toxicity.
Burnout as a Predictor of Quality of Life Among the Federal Road Safety Corps Employees in Benue State Sector Command Danladi Zakariah; Vika Tensaba Akafa; Tensaba Andes Akafa; Gloria Omonefe Oladele; Kingsley Iyoko Iseko; Izam Emmanuel David; Oche Williams Ujah
Kwaghe International Journal of Arts, Humanities and Religious Studies Vol 1 No 1 (2024): Kwaghe International Journal of Arts, Humanities and Religious Studies
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijahrs.v1i1.3983

Abstract

This study investigated the relationship between burnout and quality of life among the Federal Road Safety Corps Employees in Benue State Sector Command. The study employed cross sectional and expost facto design where 200 participants consisting of 161 (80.5%) males, 37 (18.5%) females and 2 (1.0%) did not indicate their sex. Their ages ranged from 21-60 years with means age of 35.55 (SD=7.21). Maslach Burnout Inventory (MBI) and quality of Life Scale (WHOQOL) were used for data collection using Multistage, Stratified random and systematic sampling techniques. Statistical analysis involved the use of multiple regressions. Findings indicated that, there was a significant negative relationship between burnout and quality of life among the Federal Road Safety Corps Employees in Benue State Sector Command. The result of the finding reviewed that there was a significant negative relationship between burnout and the overall quality of life among the Federal Road Safety Corps employees in Benue State Command [R=.562, R2=.316, F (3,178)=27.376, p<.001]. This implies that burnout accounted for 31.6% of the total variance observed in quality of life among the Federal Road Safety Corps employees in Benue State Sector Command. The result of the study also showed the individual contributions of the various dimensions of burnout to overall quality of life which indicated that emotional exhaustion made the highest significant negative contribution (β=-.414, t=-5.180, p<.001) followed by depersonalization (β=-.235, t=-3.081, p<.01) while personal accomplishment made no significant contribution to the model (β=.027, t=.355, p>.05) respectively. Based on the findings of this study, it was recommended that conscious efforts should be made to enhance quality of life among the Federal Road Safety Corps Employees through reduction of burnout stress inherent in the work place among the Federal Road Safety Corps Employees in Benue State Sector Command and Nigeria at large.
From Perception to Effect of Oil Spillage Among Fishermen in the Niger Delta Region of Bayelsa State, Nigeria Tensaba Andes Akafa; Solomon Ossom Asare; Adobeni Emmanuel Dennis; Daniel Konka; Smile Kobina Ametsi; Issifu Tahidu; Gloria Omonefe Oladele
Kwaghe International Journal of Arts, Humanities and Religious Studies Vol 2 No 2 (2025): Kwaghe International Journal of Arts, Humanities and Religious Studies
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijahrs.v2i2.6064

Abstract

Oil spillage continues to pose a significant environmental threat in Nigeria’s Niger Delta, leading to ecological degradation, disruption of livelihoods, and socio-political instability. This study investigates the perceptions and impacts of oil spillage among fishermen in the Biseni community of Bayelsa State. Utilizing a descriptive cross-sectional design, data were collected from 358 respondents selected through systematic random sampling. A semi-structured, interviewer-administered questionnaire was employed, and responses were analyzed using SPSS version 16. The results show that 94.4% of respondents identified pipeline corrosion from soil-related factors as a major cause of oil spillage. Other commonly perceived causes included sabotage by surveillance contractors (86.3%), pipeline vandalism (85.2%), and unemployment (84.1%). Water pollution was identified by 98.0% of respondents as the most severe environmental consequence, particularly affecting aquatic life. Health impacts were also substantial, with 96.9% reporting adverse effects, skin rashes being the most frequently cited (32.0%). Economically, 95.5% of respondents reported reduced income due to declining fish yields. Broader socio-economic impacts included perceived links to unemployment (91.9%), increased kidnapping (79.6%), lack of compensation (80.4%), displacement (35.8%), and the need to purchase drinking water (70.4%). The study concludes that repeated oil spillage and unregulated exploitation have caused significant environmental and socio-economic harm in the Biseni community. The lack of effective compensation mechanisms intensifies local grievances and underscores the urgent need for sustainable environmental governance and enhanced corporate accountability in oil-producing areas.
Effect of Aqueous Hibiscus Sabdariffa on the Histology of the Testes of Male Albino Wistar Rats Charles Ayara; Williams Oche Ujah; Favour Joel Bafai; Victor Makanjuola; Kingsley Bassey Enang; Queen Uyo Williams; Tensaba Andes Akafa; Peter Ise Uduak; Isaac John Umaru
African Journal of Clinical Medicine and Pharmacy Research Vol 1 No 1 (2024): African Journal of Clinical Medicine and Pharmacy Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajcmpr.v1i1.3974

Abstract

Medicinal plants contain physiological principles that over the years had been exploited in traditional medicine for the treatment of various ailments. Hibiscus Sabdariffa is not primarily a medicinal plant, but is used as alternative treatment to a wide variety of medical conditions. It is a plant of various psychoactive properties. This study investigated the histological effect of Hibiscus Sabdariffa aqueous solution on the testes of male albino rats. The research used 20 rats weighing 50-100g and were divided into Group A, Group B, Group C, Group D and Group E. Group A was the control group; unexposed to any form of Hibiscus Sabdariffa. Group B were exposed to the extract in a dosage of 0.5ml only in the morning. Group C were exposed to the extract in a dosage of 0.5ml in the morning and afternoon after (6) six hours. Group D were exposed to the extract in a dosage of 0.5ml in the morning, afternoon and by evening after six-hour intervals. Group E were exposed to the extract in an alternating administrative routine. In the end, the rats were sacrificed and the testes were removed and fixed in 10% formal saline solution. The testes were stained with hematoxylin and eosin. Results on the histology show changes to the histology of the testes of the group administered high doses. The results obtained from hormonal profiling shows a series of reduction in the levels of the evaluated hormones at the given dosage. Therefore, Hibiscus Sabdariffa can damage the histology of the testes at given dosage.
Histological Assessment of Aqueous Solution of Hibiscus sabariffa calyx (Zobo drink) on the Frontal Cortex and Hippocampus of Albino Wistar Rats Williams Oche Ujah; Ozzioma Praise Acha; Charles Ayara; Victor Makanjuola; Eric Agim Agaba; Queen Uyo Williams; Tensaba Andes Akafa; Isaac John Umaru
African Journal of Clinical Medicine and Pharmacy Research Vol 1 No 1 (2024): African Journal of Clinical Medicine and Pharmacy Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajcmpr.v1i1.3975

Abstract

Zobo drink which is consumed by many Nigerians, is a non-alcoholic beverage with phytoactive properties. This study investigated the histological outcome of Hibiscus sabdariffa calyx aqueous solution (Zobo drink) on the frontal cortex and hippocampus of albino wistar rats. Twenty (20) albino wistar rats were used, and grouped into a control group A, B, C, D and E. Group A was the control group. 0.5ml of Zobo drink was administered at different time interval to the experimental groups for 21 days. Zobo drink was administered to group B once a day, two times a day to group C, three times a day to group D and throughout the duration of administration to group E. In the end, the rats were sacrificed and the brain was removed and fixed in 10% formal saline solution. The frontal cortex and hippocampus were stained with Haematoxylin and eosin. Results show that no adverse effect on the frontal cortex of group B, C, D and E but shows effect on group E which is the high dose.
In-vitro Cytotoxic and Anti-vibro Cholerae Activities of Methanol Roots Extracts of Morinda citrifolia L (Noni) Isaac John Umaru; Daniel Konka; Iseko Iyoko Kingsly; Solomon Ossom Asare; Okrah George Hassan; Joseph Oteng; Tensaba Andes Akafa; Kerenhappuch Isaac Umaru
African Journal of Clinical Medicine and Pharmacy Research Vol 2 No 1 (2025): African Journal of Clinical Medicine and Pharmacy Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajcmpr.v2i1.4720

Abstract

Knowledge on medicinal properties of plants has extensively been applied all over the World to cure or ameliorate suffering of mankind. The use of remedies from plant origin covers a wide variety of maladies and constitutes an alternative way to antibiotics, which is otherwise no longer promising due to the generalized antibiotic resistance among pathogenic microorganisms. The majority of epidemic Vibrio cholerae strains have become resistant to multiple antimicrobial agents for many reasons, including mutations, horizontal gene transfers, etc. Therefore, secondary means of treatment are needed to overcome this impediment in combating cholera. Morinda citrifolia roots extensively used in traditional medicine. Therefore, the present study aims to evaluate the In-vitro Cytotoxic and Anti-vibro Cholerae Activities of Methanol Roots Extracts of Morinda citrifolia against V. cholerae isolates. Methods: Initially, different concentration of the extracts materials was subjected to qualitative phytochemical screening. Anti-V.cholerae activities were assessed by performing MIC (minimum inhibitory concentration) test using disc diffusion method with different concentrations (1.25, 2.25, 5.00, 8.00, 10.00mg/ml) where standard discs of gentamycin and meropenem (10 μg/disc) were used. Further, Brine shrimp lethality bioassay was done to evaluate the extracts’ cytotoxic activities using different concentrations (5,10, 20, 50, 100, 200, 400, 800μg/ml) against vincristine sulphate. Results: The preliminary screening confirms the presence of convenient phytochemical constituents like flavonoids, alkaloids, glycosides, tannins, etc., and are liable for the emergence of the antibacterial activities in different strains. The minimum inhibitory concentrations of methanolic Morinda citrifolia roots was found to be (a) 1.25, (b) 2.25, (c) 5, (d) 8, and (f) 10 mg/ml, respectively. Moreover, 100% mortality was observed only at the highest concentration (800 μg/ml). In comparison, the rest of the test concentration showed less than 90% mortality at the highest concentration (400 μg/ml). Conclusions: The Morinda citrifolia roots possess significant phytochemicals and showed potential anti-V. cholerae activities with mild toxicity. Hence, Morinda citrifolia (L.) roots may be recommended as potential phytotherapy against cholera disease.