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e-CliniC
Published by Universitas Sam Ratulangi
ISSN : 23375949     EISSN : -     DOI : -
Core Subject : Health,
Health Professions
Jurnal e-CliniC (eCl) diterbitkan oleh Perhimpunan Ahli Anatomi Indonesia bekerja sama dengan Fakultas Kedokteran Universitas Sam Ratulangi Manado. Jurnal ini diterbitkan 3 (tiga) kali setahun (Maret, Juli, dan November). Sejak tahun 2016 Jurnal e-CliniC diterbitkan 2 (dua) kali setahun (Juni dan Desember). Jurnal e-CliniC memuat artikel penelitian, telaah ilmiah, dan laporan kasus di bidang ilmu kedokteran klinik.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,074 Documents
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Pengaruh Riwayat Kejang Demam terhadap Kejadian Epilepsi pada Anak Marshen Budiman; Praevilia M. Salendu; Johnny L. Rompis
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44268

Abstract

Abstract: Epilepsy could cause various kinds of problems including learning difficulties, growth and development disorders, and poor quality of life of children in the future. There are several risk factors of febrile seizures that coud affect the occurrence of epilepsy inter alia abnormalities of the nervous system or there is a clear development of nervous system abnormalities before the seizure, complex febrile seizures, history of epilepsy in parents or siblings, as well as simple febrile seizures repeating four or more episodes in one year. Each of these risk factors increases the likeli-hood of epilepsy, and the combination of these risk factors increases the incidence of epilepsy. This study aimed to determine the effect of a history of febrile seizures on the incidence of epilepsy in children. This was a literature review study using three databases namely Pubmed, ClinicalKey, and Google Scholar. The keywords used were febrile seizure AND epilepsy AND children. Selection with inclusion and exclusion criteria obtained 10 literatures. The results showed that from 10 literatures reviewed, history of febrile seizures was the most common risk factor that influenced the developing of epilepsy in later life. In conclusion, history of febrile seizures is the most common risk factor for developing epilepsy in children later in life. The percentage of children with history of febrile seizure that develop to epilepsy is 3.3% - 73.8%. Keywords: febrile seizures; epilepsy; children Abstrak: Epilepsi dapat menyebabkan berbagai macam permasalahan berupa kesulitan dalam belajar, gangguan pertumbuhan dan perkembangan, serta kualitas hidup yang kurang pada anak di masa depan. Terdapat beberapa faktor risiko kejang demam yang berperan terhadap terjadinya epilepsi, di antaranya: kelainan pada sistem saraf atau adanya perkembangan kelainan yang jelas sebelum kejang, kejang demam kompleks, riwayat epilepsi pada orang tua atau suadara kandung, dan kejang demam sederhana yang berulang empat episode atau lebih dalam satu tahun. Masing-masing faktor risiko tersebut meningkatkan kemungkinan kejadian epilepsi dan kombinasi faktor risiko tersebut akan meningkatkan kejadian epilepsi. Penelitian ini bertujuan untuk mengetahui pengaruh riwayat kejang demam terhadap kejadian epilepsi pada anak. Penelitian ini berbentuk literature review, menggunakan tiga database yaitu Pubmed, ClinicalKey, dan Google Scholar. Kata kunci yang digunakan yaitu febrile seizure AND epilepsy AND children. Hasil seleksi dengan kriteria inklusi dan eksklusi mendapatkan 10 literatur. Hasil penelitian menunjukkan bahwa dari sepuluh jurnal yang di-review, didapatkan riwayat kejang demam menjadi salah satu faktor risiko yang memiliki pengaruh untuk berkembang menjadi epilepsi di kemudian hari. Simpulan penelitian ini ialah riwayat kejang demam merupakan faktor risiko terbanyak untuk berkembang menjadi epilepsi pada anak di kemudian hari. Persentase anak dengan riwayat kejang demam yang berkembang menjadi epilepsi berkisar antara 3,3% - 73,8%. Kata kunci: kejang demam; epilepsi; anak
Analisis Motivasi, Stres Kerja, dan Beban Kerja Paramedis Perawatan di Rumah Sakit Umum Gereja Masehi Injili di Minahasa (GMIM) Siloam Sonder Terkait Kinerja Virgin E. Pioh; Aaltje E. Manampiring; Silvya L. Mandey
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44269

Abstract

Abstract: Paramedics are health workers who have the most frequent contact with patients. Maximum service from health workers can improve their performance. There are several factors that affect performance, namely individual, organizational and psychological factors. This study aimed to analyze the motivation, job stress, and work stress of paramedics at GMIM Siloam Sonder Hospital related to their performance. This was a qualitative study conducted at the GMIM Siloam Sonder General Hospital using 10 informants. Data were obtained through interviews in the form of in-depth questions as well as document searching. Motivation could improve the performance of paramedics. Job stress caused the quality of paramedics to decrease. High workload affected their performance. In conclusion, motivation, job stress and workload of paramedics at RSU GMIM Siloam Sonder are related to their performance. Keywords: work motivation; job stress; workload; performance Abstrak: Paramedis perawatan merupakan tenaga kesehatan yang paling sering melakukan kontak dengan pasien. Pelayanan maksimal dari tenaga kesehatan sangat diharapkan untuk meningkatkan kinerja. Terdapat beberapa faktor yang memengaruhi kinerja yaitu faktor individu, organisasi dan psikologis. Penelitian ini bertujuan untuk menganalisa motivasi, stres dan beban kerja paramedis perawatan di RSU GMIM Siloam Sonder terkait dengan kinerja. Jenis penelitian ialah kualitatif. Penelitian dilakukan dengan menggunakan informan sebanyak 10 orang. Data penelitian diperoleh lewat wawancara berupa pertanyaan mendalam serta penelusuran dokumen. Hasil penelitian mendapatkan bahwa pemberian motivasi dapat meningkatkan kinerja paramedis perawatan. Stres kerja menyebabkan kualitas kerja paramedis perawatan menurun. Terdapat kaitan yang memengaruhi kinerja dari pemberian beban kerja yang tinggi. Simpulan penelitian ini ialah motivasi, stres dan beban kerja paramedis perawatan di RSU GMIM Siloam Sonder memiliki kaitan dengan kinerja. Kata kunci: motivasi kerja; stres kerja; beban kerja; kinerja
Korelasi antara Neutrophil-To-Lymphocyte Ratio dengan Fraksi Ejeksi pada Pasien Penyakit Jantung Koroner: Studi di Sulawesi Utara, Indonesia Janry A. Pangemanan; Agnes L. Panda; Natalia C. I. Polii; Victor Bandana; Ira Posangi; Andrew E. P. Sunardi; Singgih S. Cahyadi; Filipus M. Yofrido
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44305

Abstract

Abstract: Inflammation has a vital role in the pathogenesis of heart failure (HF) and coronary artery disease (CAD). Neutrophil-to-lymphocyte ratio (NLR) is an inflammation marker proposed to have a correlation with ejection fraction (EF). This is a simple examination and can be obtained routinely in clinical practice. This study aimed to evaluate the correlation of NLR with EF in hospitalized patients with CAD. This was an observational and analytical study with a cross-sectional design. Samples were eligible CAD patients from May until August 2019 at Prof Dr. R. D. Kandou Hospital in North Sulawesi. All patients underwent echocardiography for EF calculation, and blood examination for NLR measurement and risk factor screening. The patients were treated according to the guideline. Data were analyzed using the Spearman test in SPSS v26. The results showed that the majority of patients were male (70.2%) with mean age of 60 years old. Hypertension was found in 76.6% and smoking history in 51.1% patients. NLR was shown to have a significant correlation with EF in patients with CAD (p=0.014). In conclusion, NLR has a significant correlation with EF. Moreover, it could be a useful tool for the clinicians to predict heart failure in a specific population. Keywords: neutrophil-to-lymphocyte ratio; ejection fraction; heart failure; coronary artery disease. Abstrak: Peradangan memiliki peran penting dalam patogenesis gagal jantung (HF) dan juga penyakit arteri koroner (CAD). Rasio neutrofil-limfosit (NLR) merupakan penanda inflamasi yang diduga berkorelasi dengan fraksi ejeksi (EF), serta merupakan pemeriksaan sederhana yang dapat diperoleh secara rutin dalam praktik klinis. Penelitian ini bertujuan untuk mengetahui korelasi NLR dengan EF pada pasien rawat inap dengan CAD. Jenis penelitian ialah observasional analitik dengan desain potong lintang. Sampel penelitian ialah pasien CAD yang memenuhi syarat dirawat dari bulan Mei hingga Agustus 2019 di Rumah Sakit Prof Dr. R. D. Kandou, Sulawesi Utara. Pasien diperiksakan dengan ekokardiografi untuk perhitungan EF, dan dilakukan pemeriksaan darah untuk penilaian NLR dan skrining faktor risiko. Semua pasien dirawat sesuai dengan pedoman. Data dianalisis menggunakan uji Spearman dengan SPSS v26. Hasil penelitian mendapatkan mayoritas sampel ialah laki-laki (70,2%) dengan usia rerata 60 tahun. Hipertensi ditemukan pada 76,6% dan riwayat merokok pada 51,1% pasien. NLR terbukti memiliki korelasi bermakna dengan EF pada pasien CAD (p=0,014). Simpulan penelitian ini ialah NLR terbukti memiliki korelasi bermakna dengan EF pada pasien CAD. Selain itu NLR dapat menjadi alat bantu yang berguna bagi klinisi untuk memrediksi gagal jantung pada populasi tertentu. Kata kunci: neutrophil-to-lymphocyte ratio; fraksi ejeksi; gagal jantung; penyakit arteri koroner
Faktor Individu dan Pekerjaan yang Berhubungan dengan Kejadian Infeksi Corona Virus Disease (COVID-19) pada Pekerja di RSUP Ratatotok Buyat Renatta M. Nelwan; Diana V. D. Doda; Arthur E. Mongan
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44312

Abstract

Abstract: COVID-19 infection in hospitals can be caused by a variety of individual and work related factors. This study aimed to analyze the relationships of individual factors and occupational factors with COVID-19 infection among workers at RSUP Ratatotok Buyat. This was a cross-sectional and quan-titative study, carried out at Ratatotok Buyat Hospital in July-August 2021. Total samples were 113 respondents. The instrument used was a valid and reliable questionnaire. Univariate analysis was presented in tables of frequencies and percentages. Bivariate and multivariate analysis used binary logistic regression test. The results showed that majority of respondents were female (68%), aged 15-34 years (70%), had DIII and DIV education (54%), working duration of 0-8 hours (63.7%), and had a history of two vaccines (94%). There were relationships between COVID-19 infection and non-adherence to wearing masks (OR=26.0 CI95%=[8.9–75.4]); abnormal BMI (OR=27.7 CI95%=[9.6–80.0]); presence of comorbidities (OR=31.3 CI95%=[10.6–92.0]); relatively recent tenure (OR=2.6 CI95%=[1.1–5.8]); and working in a medical area (OR=7.4 CI95%=[3.0–18.0]). Comorbid was the most dominant factor affecting COVID-19 infection (OR=42.1 CI95%=[4–445.3]). In conclusion, non-adherence to using masks, abnormal BMI, comorbidities, relatively short duration of working, and medical work units have a positive relationships to increase the risk of COVID-19 infection with the most dominant factor influencing is a history of comorbidities. Keywords: COVID-19 infection; healthcare workers; hospital. Abstrak: Infeksi COVID-19 di rumah sakit dapat disebabkan oleh berbagai faktor terkait individu dan pekerjaan. Penelitian ini bertujuan untuk menganalisis hubungan antara faktor individu dan faktor pekerjaan terhadap infeksi COVID-19 pada pekerja RSUP Ratatotok Buyat. Jenis penelitian ialah kuantitatif dengan desain potong lintang, dilaksanakan di RSUP Ratatotok Buyat pada bulan Juli-Agustus 2021. Sampel penelitian berjumlah 113 responden. Instrumen penelitian menggunakan kuesio-ner yang valid dan reliabel. Data dianalisis secara univariat disajikan dalam tabel frekuensi dan persentase. Analisis bivariat dan multivariat menggunakan uji regresi logistik biner. Hasil penelitian menunjukkan bahwa responden paling banyak berjenis kelamin perempuan (68%), berusia 15-34 tahun (70%), berpendidikan DIII dan DIV (54%), durasi kerja 0-8 jam (63,7%), dan riwayat vaksin dua kali (94%). Terdapat hubungan antara infeksi COVID-19 dengan Tidak patuh menggunakan masker (OR=26,0 CI95%=[8,9–75,4]); IMT tidak normal (OR=27,7 CI95%=[9,6–80,0]); adanya komorbid (OR=31,3 CI95%=[10,6–92,0]); masa kerja yang relatif belum lama (OR=2,6 CI95%=[1,1–5,8]); dan bekerja di area medis (OR=7,4 CI95%=[3,0–18,0]). Faktor komorbid paling dominan memengaruhi infeksi COVID-19 (OR=42,1 CI95%=[4–445,3]). Simpulan penelitian ini ialah penggunaan masker yang tidak patuh, IMT tidak normal, riwayat komorbiditas, masa kerja belum terlalu lama dan unit kerja medis memiliki hubungan positif meningkatkan risiko terhadap infeksi COVID-19 dengan faktor yang paling berpengaruh meningkatkan risiko ialah riwayat komorbid. Kata kunci: infeksi COVID-19; pekerja fasilitas kesehatan; Rumah Sakit
Penatalaksanaan Anemia pada Penyakit Ginjal Kronik Nurfana J. Mohtar; Cerelia E. C. Sugeng; Octavianus R. H. Umboh
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44313

Abstract

Abstract: Anemia in chronic kidney disease (CKD) causes a decrease of quality of life, and increases of cardiovascular disease, cognitive impairment and death. Management of anemia in CKD with iron and erythropoiesis stimulating agents (ESA) could improve the patient's quality of life. This study aimed to determine the management of anemia in CKD focused on management of iron and ESA. This was a literature review study. Literature searching was performed by using three databases, namely ProQuest, Pubmed, and ClinicalKey. After an adjustment based on inclusion and exclusion criteria, 10 journals were obtained. The results showed that intravenous (IV) iron was a faster and superior option for iron correction than oral iron in CKD patients with anemia. Correction of anemia using ESA therapy could significantly increase hemoglobin level. If transferrin saturation (TS) was <20% and serum ferritin (SF) <100 ng/ml in CKD-ND and CKD-PD, as well as TS <20% and SF <200 ng/ml CKD-HD, erythropoiesis stimulating agents (ESA) had to be administered to increase hemoglobin levels. In conclusion, in management of anemia, iron status and iron therapy have to be evaluated first, therefore, erythropoiesis stimulating agents (ESA) administration could increase the hemoglobin level of patients with chronic kidney disease. Keywords: iron management; erythropoiesis stimulating agents; anemia; chronic kidney disease Abstrak: Anemia pada penyakit ginjal kronik (PGK) menyebabkan penurunan kualitas hidup, peningkatan penyakit kardiovaskular, gangguan kognitif, dan kematian. Penatalaksanaan anemia pada PGK dengan pemberian besi dan erythropoiesis stimulating agents (ESA) dapat meningkat-kan kualitas hidup pasien. Penelitian ini bertujuan untuk mengetahui penatalaksanaan anemia pada PGK dengan fokus pemberian besi dan ESA. Jenis penelitian ialah literature review dan pencarian data menggunakan tiga database yaitu ProQuest, Pubmed, dan ClinicalKey. Setelah dilakukan penyesuaian berdasarkan kriteria inklusi dan eksklusi didapatkan 10 artikel yang dilakukan review. Hasil penelitian menunjukkan bahwa pemberian besi intravena (IV) menjadi pilihan koreksi besi yang lebih cepat dan unggul dibandingkan besi oral terhadap penderita PGK dengan anemia Koreksi anemia dengan terapi ESA dapat meningkatkan kadar hemoglobin secara bebrmakna. Jika saturasi transferin (ST) <20% dan feritin serum (FS) <100 ng/ml pada PGK-ND dan PGK-PD, dan ST <20% dan FS <200 ng/ml PGK-HD, dapat dilanjutkan dengan pemberian ESA untuk mening-katkan kadar hemoglobin. Simpulan penelitian ini ialah dalam penatalaksanaan anemia pada penyakit ginjal kronik perlu dilakukan evaluasi status besi dan pemberian besi terlebih dahulu agar pemberian erythropoiesis stimulating agents (ESA) dapat meningkatkan kadar hemoglobin. Kata kunci: penatalaksanaan besi; erythropoiesis stimulating agent; anemia; penyakit ginjal kronik
Hubungan antara Status Nutrisi dengan Tingkat Keparahan Infeksi Dengue pada Pasien Anak di RSUP Prof. Dr. R. D. Kandou, Manado, Indonesia Rezki A. A. Naiem; Ronald Rompies; Suryadi N. N. Tatura
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44314

Abstract

Abstract: Dengue infection is a viral disease that is transmitted through mosquitoes, especially the Aedes aegypti species infected by dengue virus. Nutritional status is thought to be one of the factors that can affect the severity of dengue infection. This study aimed to determine the relationship between nutritional status and the severity of dengue infection in pediatric patients at Prof. Dr. R. D. Kandou Hospital Manado. This was an observational and analytical study with a case control design using secondary data of the medical record of Pediatric Department at Prof. Dr. R. D. Kandou Hospital. Samples were taken using the purposive sampling technique. The results obtained a total sample of 332 samples that matched the inclusion criteria. Data were analyzed using the Chi-Square test with Jamovi 1.6.23 for Windows program resulting in a p-value of 0.205 (p>0.05) for the relationship between nutritional status and the severity of dengue infection in the pediatric patients. In conclusion, there is no relationship between nutritional status and the severity of dengue infection in pediatric patients at Prof. Dr. R. D. Kandou Hospital, Manado. Keywords: dengue infection; nutritional status; children Abstrak: Infeksi dengue merupakan penyakit virus yang penularannya melalui perantara gigitan nyamuk terutama spesies Aedes aegypti yang terinfeksi oleh virus dengue. Status nutrisi diduga menjadi salah satu faktor yang dapat memengaruhi tingkat keparahan infeksi dengue. Penelitian ini bertujuan untuk mengetahui hubungan antara status nutrisi dengan tingkat keparahan infeksi dengue pada pasien anak di RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ialah analitik observasional dengan rancangan case control menggunakan data sekunder dari Bagian Ilmu Kesehatan Anak RSUP Prof. Dr. R. D. Kandou Manado. Sampel diambil menggunakan teknik purposive sampling, Hasil penelitian mendapatkan total sampel sebanyak 332 sampel yang sesuai dengan kriteria inklusi. Data penelitian dianalisis menggunakan uji Chi-Square dengan program Jamovi 1.6.23 for Windows yang mendapatkan nilai p=0,205 (p>0,05) untuk hubungan antara status nutrisi dengan tingkat keparahan infeksi dengue pada pasien anak di RSUP Prof. Dr. R. D. Kandou Manado. Simpulan penelitian ini ialah tidak terdapat hubungan bermakna antara status nutrisi dengan tingkat keparahan infeksi dengue pada pasien anak di RSUP Prof. Dr. R. D. Kandou Manado, Kata kunci: infeksi dengue; status nutrisi; anak
Bacterial Profile and Antibiotic Susceptibility Pattern of Patients at Pre- and Post-Urologic Endoscopy Procedures at Prof. Dr. R. D. Kandou Hospital, Manado, Indonesia Paulus Oroh; Ari Astram; Christof Toreh; Eko Arianto; Frendy Wihono; Windy Wariki; Hessyani Raranta
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44315

Abstract

Abstract: Development of antibiotics resistance condition has been at a concerning state while data on the distribution of bacterial profile and the incidence of resistances in Indonesia are currently still limited at hospital environment, including at Prof. Dr. R. D. Kandou Hospital in Manado, Indonesia. This study aimed to obtain the profile of bacteria and the pattern of susceptibility to antibiotics in patient's urine before and after urologic endoscopy procedures at RSUP Prof. Dr. R. D. Kandou. This was an observational study with a cross sectional design. Sampling was performed with the one-group test technique of Lemeshow. The data collection technique used urine culture test by calculating the percentages. The results obtained 42 patients as subjects. The urinary bacterial profile of patients who underwent urologic endoscopy procedures at Prof. Dr. R. D. Kandou Hospital were dominated by Gram-negative bacteria, namely E. coli (23.8%), Klebsiella (4.8%), Acinetobacter baumannii (2.4%); 69% of urine samples showed negative culture results. The susceptibility pattern of bacteria to antibiotics in the subjects’ urine showed 100% sensitivity to the given antibiotics. No nosocomial infection was found, however, nosocomial infection yet could not be excluded. In conclusion, bacteria found in the patients’ urine are dominated by Gram-negative bacteria namely Escherichia coli, Klebsiella, and Acinetobacter baumannii which are still sensitive to antibiotics. Most urine samples showed negative results, and no nosocomial infection was found. Keywords: bacterial profile; bacterial susceptibility; antibiotic; urological endoscopic procedure
Pengaruh Aktivitas Fisik terhadap Profil Lipid Penderita Penyakit Jantung Koroner Iin Mutmainnah; Linda W. A. Rotty; Frans E, N. Wantania
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44317

Abstract

Abstract: Increased level of blood lipid is one of the important causes that contribute to coronary heart disease (CHD). Physical activity is known to affect blood cholesterol level. Moreover, physical activity in the form of exercise performed for 30 minutes regularly 3-5 days a week can reduce the level of low-density lipoprotein (LDL) cholesterol and increase the level of high-density lipoprotein (HDL) cholesterol. This study aimed to determine the relationship between physical activity and lipid profile in patients with CHD. This was a literature review study. There were 10 articles in this study. The results showed that there was a change in the lipid profile after physical activity in patients with CHD, however, in several studies, the lipid profile did not change significantly. In conclusion, patients with coronary heart disease (CHD) without contraindications who do moderate to high intensity physical activity will get benefit of improving blood lipid profiles. Keywords: coronary heart disease; llipid profile; physical activity Abstrak: Peningkatan kadar lipid darah merupakan salah satu penyebab penting yang berkontribusi terhadap penyakit jantung koroner (PJK). Aktivitas fisik diketahui dapat memengaruhi kadar kolesterol dalam darah. Aktivitas fisik berupa olahraga yang dilakukan selama 30 menit secara rutin 3-5 hari dalam seminggu dapat menurunkan kadar kolesterol low-density lipoprotein (LDL) dan meningkatkan kadar kolesterol high-density lipoprotein (HDL). Penelitian ini bertujuan untuk mengetahui hubungan aktivitas fisik terhadap kadar profil lipid pada penderita penyakit jantung koroner. Jenis penelitian ialah literature review. Hasil penelitian berdasarkan 10 literatur mendapatkan adanya perubahan profil lipid penderita PJK setelah melakukan aktivitas fisik, namun pada beberapa penelitian kadar profil lipid tidak berubah secara bermakna. Simpulan penelitian ini ialah penderita penyakit jantung koroner (PJK) tanpa kontraindikasi yang melakukan aktivitas fisik dengan intensitas sedang sampai tinggi akan memperoleh manfaat berupa perbaikan profil lipid darah. Kata kunci: penyakit jantung coroner; profil lipid; aktivitas fisik
Mekanisme Terjadinya Hiperbilirubinemia pada Bayi Berat Lahir Rendah Grasia P. Gerungan; Rocky Wilar; Max F. J. Mantik
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44319

Abstract

Abstract: Hyperbilirubinemia is frequently found in newborns, especially in low birth weight (LBW) infants (less than 2,500 g). Hyperbilirubinemia is an increase in bilirubin higher than 5 mg/dL which clinically manifests as icterus. This study aimed to evaluate the relationship between LBW and the incidence of hyperbilirubinemia as well as the underlying mechanism. This was a literature study. Article searching used databases of Pubmed and Google Schoolar and the keywords were Hyperbilirubinemia AND Low birth weight NAD Neonatal Jaundice. The results showed a relationship between LBW and the incidence of hyperbilirubinemia. There were increases of hemoglobin, heme catabolism, and destruction of bilirubin due to liver immaturity, impaired liver function and perfusion and bilirubin conjugation ability, less of albumin as the transportation protein and uridine diphosphate glucuronyltransferase (UDP-GT) to convert indirect bilirubin to direct bilirubin in the liver. In conclusion, there is a relationship between low birth weight and hyperbilirubinemia that occurs due to liver immaturity, impaired liver function and perfusion, and less of albumin and UDP-GT enzyme. Keywords: hyperbilirubinemia; low birth weight; neonatal jaundice Abstrak: Hiperbilirubinemia merupakan masalah yang sering terjadi pada bayi baru lahir terlebih bayi dengan berat lahir rendah (<2.500 gram). Hiperbilirubinemia merupakan peningkatan kadar bilirubin serum >5mg/dL yang bermanifestasi klinis berupa ikterus. Penelitian ini bertujuan untuk mengetahui hubungan antara BBLR dengan kejadian hiperbilirubinemia dan mekanisme terjadinya. Jenis penelitian ialah suatu literature review. Pencarian artikel menggunakan Pubmed dan Google Schoolar dengan kata kunci Hyperbilirubinemia AND Low birth weight AND Neonatal Jaundice. Hasil penelitian mendapatkan adanya hubungan antara BBLR dengan kejadian hiperbilirubinemia. Terdapat peningkatan jumlah hemoglobin, katabolisme heme dan penghan-curan bilirubin yang terjadi antara lain karena imaturitas hati yang belum optimal mengkonju-gasikan bilirubin, terganggunya fungsi dan perfusi hati serta kemampuan mengkonjugasi bilirubin, rendahnya kadar protein albumin sebagai transportasi dan enzim uridin difosfat glukoronid transferase (UDP-GT) untuk mengonversi bilirubin indirek menjadi bilirubin direk di dalam hati. Simpulan penelitian ini ialah terdapat hubungan antara BBLR dengan hiperbilirubinemia yang dapat terjadi karena imaturitas hati, terganggunya fungsi dan perfusi hati, serta kurangnya protein albumin dan enzim UDP-GT. Kata kunci: hiperbilirubinemia; low birth weight; neonatal jaundice
Analisis Citra Rumah Sakit Umum GMIM Bethesda Tomohon pada Unit Rawat Jalan Tahun 2020 Patrick Muljono; Aaltje E. Manampiring; Fatimawali Fatimawali
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44320

Abstract

Abstract: Hospital image could affect the attitude and behaviour of patients towards the hospital. This study aimed to evaluate the relationship between the variables studied and the image of Rumah Sakit Umum GMIM Bethesda (RSUGB). This was a descriptive study with a cross sectional design. The independent variables in this study were familiarity, emotional aspect, service, environment, and finance. The dependent variable was the image of RSUGB. Data were statistically analyzed with the chi square test using the SPSS version 22 computer program. The results showed that most respondents (89.0%) felt that hospital familiarity was good; (68.2%) felt emotional towards a good hospital; (67.9%) felt that the service at the hospital was good; (87.2%) felt that the environment of the hospital was good; and (68.8%) felt that the financial rates at the hospital were good. The chi square test or cross tabulation of the five independent variables on the dependent variable indicated that only the service variable towards hospital image had a p-value < 0.05 (p=0.018). Other variables such as familiarity (p=0.166), emotional aspect (p=0.473), environment (p=0.057), and finance (p=0.200) had p-values >0.05. In conclusion, there is a relationship between service and the image of Rumah Sakit Umum GMIM Bethesda (RSUGB), however, there are no relationships between familiarity, emotional aspect, environment, and finance with the hospital image. Keywords: familiarity; emotional aspect; service; environment; finance; hospital image Abstrak: Citra sebuah rumah sakit berdampak pada sikap dan perilaku pasien terhadap rumah sakit tersebut. Penelitian ini bertujuan untuk mengetahui hubungan variabel yang diteliti dengan citra Rumah Sakit Umum GMIM Bethesda (RSUGB). Jenis penelitian ialah deskriptif dengan desain potong lintang. Variabel bebas ialah familiaritas, emosional, pelayanan, lingkungan dan keuangan sedangkan variabel terikat ialah citra RSUGB. Analisis data secara univariat dan bivariat menggunakan uji chi square dengan bantuan program komputer SPSS versi 22. Hasil penelitian menunjukkan sebagian besar responden (89,0%) merasa familiaritas rumah sakit baik; (68,2%) merasa emosional terhadap rumah sakit baik; (67,9%) merasa pelayanan pada rumah sakit baik; (87,2%) merasa lingkungan di rumah sakit baik; dan (68,8%) merasa tarif keuangan di rumah sakit baik. Pada uji chi square atau tabulasi silang dari kelima variabel bebas terhadap variabel terikat didapatkan hanya variabel pelayanan dengan citra rumah sakit nilai p<0,05 (p=0,018). Variabel lainnya seperti familiaritas (p=0,166), aspek emosional (p=0,473), lingkungan (p=0,057), dan keuangan (p=0,200) mendapatkan nilai p>0,05. Simpulan penelitian ini ialah terdapat hubungan antara pelayanan dengan citra Rumah Sakit Umum GMIM Bethesda (RSUGB) namun tidak terdapat hubungan antara familiaritas, aspek emosi, lingkungan dan keuangan dengan citra rumah sakit. Kata kunci: familiaritas; emosional; pelayanan; lingkungan; keuangan; citra rumah sakit

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