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EDITOR IN CHIEF Gerald H. Tamuntuan, Universitas Sam Ratulangi, Indonesia MANAGING EDITOR Verna A. Suoth, Universitas Sam Ratulangi, Indonesia BOARD OF EDITOR Audy Wuntu, Fakultas MIPA Univesitas Sam Ratulangi BOARD OF EDITOR Nio Song Ai, Universitas Sam Ratulangi, Indonesia BOARD OF EDITOR Nelson Naingolang, Universitas Sam Ratulangi, Indonesia
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Kota manado,
Sulawesi utara
INDONESIA
Jurnal MIPA
Published by Universitas Sam Ratulangi
ISSN : -     EISSN : 23023899     DOI : https://doi.org/10.35799/jmuo.10.2.2021.33592
Core Subject : Science, Education,
Biochemistry, Genetics & Molecular Biology Chemistry Mathematics Physics
Jurnal MIPA menjadi sarana publikasi bagi akademisi dan peneliti. Jurnal MIPA mempublikasikan artikel hasil penelitian di bidang : Matematika Fisika Biologi Kimia
Arjuna Subject : Umum - Umum
Articles 9 Documents
 1 
Search results for , issue "Vol 11, No 1 (2022)" : 9 Documents clear
Analisis Hubungan Kekerabatan Fenetik serta Potensi Kegunaan Varietas Portulaca oleracea dan Portulaca grandiflora di Desa Grogol, Kelurahan Dukuh, Kota Salatiga Prasgi, Henokh Christian; Pratama, Dimas Seno Bagus; Kapitarauw, Agnesya Giovani Putri Cendana; Kasmiyati, Sri
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.35054

Abstract

Portulacaceae merupakan tumbuhan dikotil dari famili Portulacaceae yang dapat hidup di berbagai kondisi tanah sehingga disebut gulma serta memiliki bentuk dan variasi warna bunga yang beragam untuk dijadikan tanaman hias. Portulaca memiliki berbagai kegunaan untuk kesehatan, sehingga diperlukan suatu program pemuliaan tanaman yang didasarkan pada kekekerabatan menggunakan karakter morfologinya. Tujuan penelitian ini untuk mengetahui hubungan kekerabatan atau fenetik serta sifat kegunaan dari beberapa varietas Portulaca oleracea dan Portulaca grandiflora di Desa Grogol, Kelurahan Dukuh, Kota Salatiga dengan metode Analysis of Cluster dan Euclidean Matrix of Index Dissimilarity. Penelitian ini dilaksanakan di Desa Grogol, Kelurahan Dukuh, Kecamatan Sidomukti, Kota Salatiga, Jawa Tengah. Jenis penelitian deskiptif eksploratif. Karakter yang digunakan sebanyak 22 buah yang dianalis denggan program PAST. Hasil penelitian menunjukkan 6 anggota famili Portulacaceae yang dianalisis dengan metode Analysis of Cluster membentuk 2 klaster utama yaitu klaster 1 Portulaca grandiflora (Oranye, Putih, dan Pink) serta klaster 2 Portulaca oleracea (Kuning. Merah, dan Pink) dengan indeks kesamaan terbesar pada P. grandiflora Oranye dengan P. grandiflora Putih serta P. grandiflora Putih dengan P. grandiflora Pink (99%), sedangkan yang terendah antara Portulaca grandiflora Oranye dengan Portulaca oleracea Merah (94,8038%). Pigmen, faktor genetik, dan lingkungan menyebabkan perbedaan karakter. Kedua spesies ini berpeluang besar dalam pengembangan obat-obatan karena senyawa dan sifatnya.
Profil Penetrasi Sediaan Gel Antioksidan Ekstrak Kayu Manis (Cinnamomum burmanii) dengan Variasi Hydrocolloid sebagai Gelling agent Siampa, Jainer Pasca; Wiyono, Weny Indayany; Lestari, Utami Sasmita; Lebang, Julianri Sari; Antasionasti, Irma
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.35787

Abstract

The exposure of sunlight consisting UV radiation has been reported to be the main cause of skin cancer and contribute about 80% of the incidence of skin damage. In an attempt to overcome this problem, antioxidant agents have been used both orally and topically. Compared to oral administration, topical route has been found to be preferred due to the direct action to the desired site. Amongst topical preparation, gel possesses numerous because it provides a cool and fresh sensation. Here, we developed gel antioxidant containing cinnamon extract as active ingredient. Cinnamon was selected as it has a very strong antioxidant activity. This study aimed to obtain the penetration profile of the antioxidant gel of cinnamon extract prepared from two different hydrocolloid agents. The gels were made using various concentrations of Carbopol 940 and NaCMC. The prepared gels were further characterized for their antioxidant capacities using the DPPH free radical scavenging method and their total phenolic contents using the spectrophotometric method. The formulation possessing the strongest antioxidant capacity was continued for ex vivo penetration study using Franz diffusion cells. The results exhibited that the total phenolic value of the cinnamon extract obtained was 908.38 ± 6.54 mg GAE/g extract. The penetration percentages for the formula with Carbopol and NaCMC bases were 53.310 ± 1.217% and 27.969 ± 1.151%, respectively, and the retention percentages were 28.495 ± 0.031% and 18.356 ± 0.191%, respectively. Based on these findings, we concluded that cinnamon extract could potentially be formulated into antioxidant gel preparations and formulas based on Carbopol showed the best penetration profile.
EVALUASI STABILITAS FISIK KRIM M/A EKSTRAK BIJI ALPUKAT (Persea americana Mill.) DENGAN VARIASI ASAM STEARAT DAN TEA SEBAGAI EMULGATOR Mansauda, Karlah Lifie Riani; Jayanto, Imam; Tunggal, Ryan Irwanto
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.36786

Abstract

Biji alpukat (Persea americana Mill.) telah diteliti mengandung senyawa-senyawa metabolit sekunder yang memiliki banyak manfaat misalnya antioksidan, antimikroba, dan antifungi. Penelitian ini bertujuan untuk memformulasikan dan mengevaluasi stabilitas fisik krim ekstrak biji alpukat dengan variasi asam stearat dan TEA sebagai agen pengemulsi. Biji alpukat diekstraksi dengan menggunakan pelarut aseton 70% kemudian diformulasikan menjadi krim M/A. Formulasi krim diuji stabilitasnya dengan uji penyimpanan pada suhu  tinggi (40±2ºC), suhu kamar (25º±2C), dan pada suhu rendah (4±2ºC) selama 8 minggu. Krim juga diuji stabilitasnya menggunakan uji sentrifugasi dan cycling test. Hasilnya krim F1 dan F2 berhasil mempertahankan karakteristik fisiknya seperti penampilan, pH, daya sebar dan daya lekat selama penyimpanan dan memenuhi spesifikasi pada uji sentrifugasi dan cycling test.
Eksplorasi Metode Geolistrik Resistivitas: Studi Kasus Zona Sesar Utama Manado dan Akuifer Air Tanah Di Kabupaten Minahasa Utara As'ari, As'ari; Tongkukut, Seni Herlina Juita; Suoth, Verna Albert; Panjaitan, Sarmaria; Akasi, Iftita Anugraini; Pulu, Meidy Rosalie
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.36103

Abstract

The Manado Fault is a fault located in North Sulawesi which is through the North Minahasa Regency. The fault area is a weak zone that is formed when a crack occurs on the earth's surface, a gap with a certain depth and width is formed, because the natural process of the gap is filled by the surrounding soil material. This weak zone has the potential to become a reservoir for rainwater, which can become a groundwater aquifer. The formation of fractures depends on the geology of an area, fracture characteristics such as the width and depth of the fracture affect the potential for groundwater stored as aquifers. This study aims to identify the influence of geology on the physical parameters of the fault that determine the potential presence of groundwater aquifers in North Minahasa Regency. The faults identified as fractures in Watutumou II Village, Kalawat District and Rap Rap Village, Airmadidi District, North Minahasa Regency are associated with fluids and form groundwater aquifers. The potential for groundwater storage is related to geological conditions following the trend of depth to fracture width with a gradient of -0.0588.
Rancang Bangun Oksimeter Pulsa yang Diintegrasikan dengan EKG sebagai Alat Ukur Multimodal untuk Analisis HRV Pang, David; Kolibu, Hesky Stevy
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.39058

Abstract

Analisis variabilitas denyut jantung (HRV) berdurasi panjang berguna sebagai teknik noninvasif untuk asesmen terhadap aktivitas sistem saraf otonom. Analisis Ini menginformasikan banyak faktor fisiologis dan patologis yang memodulasi detak jantung normal. Namun performa sistem analisis HRV sangat bergantung pada keakurasian pendeteksian R-peak dari QRS complex. Detak yang disebabkan oleh kesalahan deteksi dapat menggangu hasil HRV, yang mengakibatkan masalah signifikan dalam interpretasinya. Terutama sifatnya yang berdurasi panjang, maka diperlukan sistem deteksi R-peak yang andal. Penelitian ini bertujuan membangun sistem akuisisi data multimodal dari data EKG dan data pulsa SPO2 untuk mendapatkan hasil deteksi R-peak yang lebih reliabel dibanding dengan hanya menggunakan data EKG saja. Namun demikian, hasil akhir sistem keseluruhan ditentukan oleh metode pendeteksian yang nantinya digunakan .
Simulasi Optimasi Suhu dari Sistem Pemanasan Temperatur Tinggi Berbasis Gelombang Mikro Sagai, Fingken Stevanus; Pandara, Dolfie Paulus; Kolibu, Hesky Stevy; Tongkukut, Seni Herlina Juita; Ferdy, Ferdy; Tamuntuan, Gerald Hendrik; Abidjulu, Gilbert
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.36151

Abstract

Telah dilakukan penelitian simulasi untuk menganalisis pengaruh variasi dimensi geometri tungku, daya oven gelombang mikro dan waktu pemanasan terhadap suhu tungku, dan mengoptimasi suhu tungku dalam pemanasan dengan gelombang mikro dari variasi parameter yang digunakan. Tungku kubus dengan panjang sisinya dan tungku silinder dengan diameter dan tingginya masing-masing memiliki ukuran yang sama yaitu 50 mm untuk tipe I, 70 mm untuk tipe II dan 90 mm untuk tipe III, yang terbuat dari material SiC dipanaskan dalam oven gelombang mikro pada daya 100%, 75% dan 50% dari daya maksimum 1,3 kW. Pemanasan tungku ini disimulasikan menggunakan perangkat lunak COMSOL Multiphysics. Hasil simulasi dari setiap parameter dilakukan analisis dan optimasi untuk mencapai suhu optimum 500oC dalam waktu yang singkat dengan konsumsi energinya yang rendah. Hasil simulasi yang diperoleh menunjukkan bahwa variasi parameter memengaruhi suhu yang dihasilkan tungku dan distribusi suhu di dalam tungku. Optimasi pada tungku kubus tipe II (ukuran 70 mm) yang dipanaskan dalam oven gelombang mikro dengan daya 1,3 kW (100%) mencapai suhu optimum 500oC dalam waktu relatif singkat sebesar 7 menit 33 detik (453 detik) dan konsumsi energi relatif rendah sebesar 5,889 × 105 J.Simulation research has been conducted to analyze the effect of variations in the dimensions of the furnace geometry, microwave oven power, and heating time on the furnace temperature, and optimize the furnace temperature in microwave heating from a variety of parameters used. The cube furnace with side length and cylindrical furnace with diameter and height respectively have the same size, namely 50 mm for type I, 70 mm for type II, and 90 mm for type III, which are made of SiC material heated in a microwave oven at power 100%, 75% and 50% of the maximum power of 1,3 kW. The heating of this furnace was simulated using COMSOL Multiphysics software. The simulation results for each parameter are analyzed and optimized to achieve the optimum furnace temperature of 500oC in a short time with low energy consumption. The simulation results obtained show that the parameter variations affect the temperature produced by the furnace and the temperature distribution in the furnace. Optimization of the type II cube furnace (size 70 mm) heated in a microwave oven with a power of 1,3 kW (100%) reaches the optimum temperature of 500oC in a relatively short time of 7 minutes 33 seconds (453 seconds) and relatively low energy consumption of 5,889 × 105 J.
Uji Aktivitas UV Protektif Secara In Vivo pada Krim dari Bahan Aktif Cangkang Telur Ayam Ras Menggunakan Hewan Coba Kelinci Betina Usman, Yusnita; Muin, Rahmatullah
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.36911

Abstract

Previously, an in vitro study of the SPF value of a cream formulation with active ingredients from broiler eggshells was conducted using UV-vis spectrophotometry at a wavelength of 290-320 nm and obtained an SPF value of 8.335 at a concentration of 9000 ppm. This study aims to continue testing the UV protective activity in vivo on creams from these active ingredients with combination of adding 5% titanium dioxide. The experimental animals used consisted of 12 female rabbits divided into 4 groups, namely (1) positive control: market product spf 15, (2) Negative control: cream base, (3) Formula I: (15% egg shell), and (4 ) Formula II: (a combination of 15% eggshell and 5% titanium dioxide). The activity test was carried out by determining (SPF) against UV-B rays in vivo in 4 groups of experimental animals by comparing the Minimum Erythema Dose (MED) value on protected skin with those not protected by sunscreen. The test results were then analyzed based on the category of sunscreen uv protection. The results showed the SPF value of Group 1; 2; 3 and 4 respectively 15.3; 0 ; 8.55 and 12.37. Group 4 has the same activity as group 1 and has better activity than group 3.
Pengaruh Pemberian Sari Buah Salak (Salacca zalacca) terhadap Profil lipid dan Berat Badan Tikus Model Hiperlipidemia dan Obesitasda Datu, Olvie Syenni; Lebang, Julianri Sari; Rumondor, Erladys Melindah
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.36530

Abstract

Cardiovaskular disease is the number one cause of death in the world, an estimated 17.9 million people die each year. Several risk factors that contribute to the occurrence of heart disease such as hypertension, diabetes mellitus, hyperlipidemia, and obesity. Snake Fruit is a fruit that is available in large quantities both in volume and variety. Snake Fruit is rich in antioxidants that can be used to treat hyperlipidemia and overweight. North Sulawesi is one of the centers of Snake Fruit production, especially in the southeast Minahasa area. This study aimed to test the effectiveness of Snake Fruit juice on the lipid profile of hyperlipidemic and obese rats induced by a high-fat diet in the form of used cooking oil, quail egg yolk and 0.01% PTU solution. The study used 5 groups, namely the negative control group was given aquadest, the positive control group was given simvastatin and the treatment group was given Snake Fruit juice with concentrations of 2%, 4% and 8%. The parameters observed in this study were body weight, lipid profile, and glucose profile. blood. The study showed that the administration of Snake Fruit juice had a significant effect on the lipid profile of rats for all parameters on the lipid profile and had a significant effect on weight loss and blood glucose levels where p < 0.05 and there was no significant difference between each treatment group in both lipid profile parameters. , body weight and blood glucose levels.
Persepsi Kelompok Pemandu Wisata Terhadap Konservasi Penyu di Pesisir Pulau Bunaken, Taman Nasional Bunaken, Manado, Sulawesi Utara Rumbay, Julia Angel; Koneri, Roni; Langoy, Marnix; Handoyo, Eko; Wijaya, Pandu
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.38902

Abstract

Public perception of turtle conservation in an area will determine the success of turtle conservation activities. This study aims to analyze the perception of tour guide groups towards turtle conservation on the coast of Bunaken Island, Bunaken National Park, Manado, North Sulawesi. The research method was carried out by means of observation and surveys. Collecting data in the form of interviews with a questionnaire guide. The selection of respondents was carried out by purposive sampling with the target group of tour guides, especially dive guides. Data analysis was carried out using a qualitative descriptive method. The results showed that most of the respondents (78%) already understand about turtle conservation and no longer consume turtles (100%). The turtle habitat which includes coral reefs and seagrasses still supports the presence of turtles and turtles are almost visible at all observation locations. The understanding of turtle conservation by dive guides is quite good, but to maintain the sustainability of conservation so that it is maximized, it is necessary to provide guidance and supervision to the diving guides and also to the surrounding community.

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