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Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)

Galenika
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Published by Universitas Tadulako

ISSN : 24427284 EISSN : 24428744 DOI : https://doi.org/10.22487/j24428744

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (E-ISSN: 2442-8744) (p-ISSN: 2442-7284), is an open access journal (print and e-journal) focusing on the scientific works in the field of Pharmacy and Pharmaceutical Science. The articles of this journal are published every six months, that is March and October (2 issues per year). This journal is developed by Department of Pharmacy, Faculty of Mathematics and Natural Science, Tadulako University and has been identified in Crossref with the DOI Number : 10.22487/j24428744. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) has been accredited by Kemenristekdikti as Sinta 3 starting from Volume 5 No 1 2019.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 8 Documents

Search results for , issue "Vol. 2 No. 1 (2016): (March 2016)" : 8 Documents clear

STUDI ETNOFARMASI TUMBUHAN BERKHASIAT OBAT PADA SUKU BANGGAI DI KABUPATEN BANGGAI LAUT, PROVINSI SULAWESI TENGAH Nur Khairiyah; Syariful Anam; Akhmad Khumaidi
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 1 (2016): (March 2016)
Publisher : Universitas Tadulako

A study of nutritious herbs etnopharmacy has been done to Banggai ethnic from March to June 2015 in Banggai Laut Regency, Central Sulawesi. This research aims at identifying every kind of herbs parts used as traditional medicine, types of diseases cured using herbs by Banggai ethnic in Banggai Laut Regency, and the percentage of the usage by the informant about herbs as a traditional medicine. This is a descriptive research that uses qualitative method and take the sample purposively through open-ended interview involved 7 informants asked by questionnaire. The result of this research revealed that there are 54 types of herbs divided into 31 family used as medicine. The most widely used herbs is from 5 species of Zingiberaceae family and Lamiaceae family. Interview result revealed that there are 10 types of chronic diseases, 3 infectious diseases, non-communicable diseases 27, and 5 used for health care body. The parts of herbs used are leaf (49 percent), stem, sap, fruit, rhizomes, roots, tubers, herbs and bark. The Banggai ethnic precede the herbs through boiled, mashed, squeezed, shredded, soaked, brewed and then consumed, drunk, rubbed, pasted, applied directly. Processing methods most often done is boiled and drunk the herbs straightly. The higher belief the society has in the herbs ability to cure the diseases the higher use of herbal medicine as an alternative of diseases healing.

POTENSI EFEK HIPOGLIKEMIK KOMBINASI EKSTRAK ETANOL UMBI BAWANG HUTAN (Eleutherine bulbosa) DAN KULIT BATANG KAYU MANIS (Cinnamomum burmanii) PADA TIKUS (Rattus norvegicus) DIABETES YANG DIINDUKSI STREPTOZOTOSIN DAN TOLERANSI GLUKOSA Devyayu Prabaningsih; Yuliet Yuliet; Ririen Hardani
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 1 (2016): (March 2016)
Publisher : Universitas Tadulako

Research on potential hypoglycemic effects of ethanol extract combination of onion forest bulbs (Eleutherine bulbosa) and burmani cortex (Cinnamomum burmanii) in streptozotocin (STZ)-induced diabetic and glucose tolerant rats (Rattus norvegicus) has been conducted. This study aimed to determine the hypoglycemic effect and the effective dose of ethanol extract combination of forest onion bulbs and cinnamon cortex. Extract was obtained by maceration using 96% ethanol. A number of 30 male rats were divided into 6 groups and each group consisted of 5 rats. The first group (negative control) was given Na.CMC; the second group (positive control 1) glibenclamide 0.45 mg/kgBW; the third group (positive control 2) acarbose 9 mg/kgBW; while the 4th, 5th, and 6th were successively given combination of ethanol extract of forest onion bulbs and cinnamon cortex at doses of 100+100, 50+50, and 25+25 mg/kgBW. Each rat group was intraperitoneally (ip) induced with STZ 40 mg/kgBW and then treated for 14 days, after the rats developed diabetic condition, glucose tolerance test was performed with the induction of sucrose 150mg/kgBW which was continued with observation in minute 60, 90, 120, 150, and 180. Treatment data were analyzed using ANOVA (analysis of variance) with 95% confidence interval. The results showed that ethanol extract combination of forest onion bulbs and cinnamon cortex had potential hypoglycemic effects in male rats of which the most effective combination dose was at a dose of 50 + 50 mg/kgBW

AKTIVITAS HEPATOPROTEKTOR SARI BUAH LABU KUNING (Cucurbita moschata Duchesne.) PADA TIKUS (Rattus norvergicus) YANG DIINDUKSIKAN KARBON TETRAKLORIDA Indrawan Aditya; Ihwan Ihwan; Jamaluddin Jamaluddin
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 1 (2016): (March 2016)
Publisher : Universitas Tadulako

One of the plants that are often used in traditional medicine is the fruit of pumpkin used to treat hepatitis manner pumpkin fruit cut into small pieces and then steamed, then eaten .Pumpkin fruits contain active compounds such as saponins, tannins, flavonoids and beta-carotene. Beta-carotene is converted in the body into vitamin A is beneficial for the growth, maintenance of body tissues and to reduce the risk of cancer and heart disease. This study aims to determine pumpkin juice has a hepatoprotective activities on liver function by looking at parameters SGPT and SGOT in rats after induced CCl4. Type of experimental research using True Experimental research design design. Test animals were grouped into 5 groups, each group consisting of 3 rats. The first group of positive control (Methicol®), the second group negative control (CCl4), the third group of pumpkin juice 25%, the fourth group of pumpkin juice 50%, the fifth group of pumpkin juice 75%. From the results of this study concluded that the pumpkin juice 75% effective as a hepatoprotective by looking at parameters SGPT is 48 U/liter and SGOT is 66 U/liter in rats after induced carbon tetrachloride

PENGARUH PEMBERIAN EKSTRAK DAUN SALAM (Syzygium polyanthum Wight.) TERHADAP GLIBENKLAMID DALAM MENURUNKAN KADAR GLUKOSA DARAH MENCIT (Mus musculus) YANG DIINDUKSI ALOKSAN Nur Hikmah; Yuliet Yuliet; Khildah Khaerati
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 1 (2016): (March 2016)
Publisher : Universitas Tadulako

The use of herbal medicines and synthetic drugs simultaneously carried out by diabetics for the maintenance of blood glucose levels, such as the use of glibenclamide and bay leaf. This research was carried out to know the impact of administration bay leaf extract on glibenclamide in lowering blood glucose levels on mices that induced by alloxan. This research used 40 male mices which were divided into 8 groups. Before the experiment, the mices were first induced by alloxan (70 mg/kg BW) intravenously. The negative control was the group that given Na CMC 0,5%, KG was the control of glibenclamide 0,65 mg/kg BW, group DS1, DS2, DS3 were the control of single bay leaf extract with each dose 250 mg/kg BW, 500 mg/kg BW, and 750 mg/kg BW, group KD1, KD2, KD3 were the combination group of glibenclamide and bay leaf extract with each dose glibenclamide combined bay leaf extract 250 mg/kg BW, glibenclamide combined bay leaf extract 500 mg/kg BW, and glibenclamide combined bay leaf extract 750 mg/kg BW, with an hour interval. The data were statistically analyzed using ANOVA (Analysis of Variance) at 95% confidence interval with parameter of blood glucose levels difference between before and after treatment. The results showed that the administration of bay leaf extract gave significant impact on glibenclamide in lowering blood glucose levels and the effective dose was the combination of glibenclamide 0,65 mg/kg BW and bay leaf extract 250 mg/kg BW

IDENTIFIKASI DRUG RELATED PROBLEMS (DRPs) PADA PASIEN ANAK GASTROENTERITIS AKUT DI INSTALASI RAWAT INAP RSU ANUTAPURA PALU Arlinda Arlinda; Alwiyah Mukaddas; Ingrid Faustine
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 1 (2016): (March 2016)
Publisher : Universitas Tadulako

Acute gastroenteritis, one of the most common disease in children and one of the causes of children’s death in the world, has a great chance of the occurrence of Drug Related Problems (DRPs). This study aimed to determine the incidence of potential DRPs occurred in pediatric inpatients of acute gastroenteritis in Anutapura General Hospital, Palu, Central Sulawesi. This was a prospective observational study done by collecting primary data from the observation and secondary data from medical records of pediatric inpatients aged from 1 month to 14 years and diagnosed with acute gastroenteritis with or without dehydration. Data were then analyzed and descriptively presented including drug use without indication, wrong drug, drug dose too low, drug dose loo high, and untreated indication. The results showed that there were 115 cases of DRPs. The most DRPs found was drug use without indication as many as 56 cases (48.7%), while the others successively were drug dose too low 26 cases (22.6%), untreated indication 16 cases (14%), drug dose too high 15 cases (13%), and wrong drug 2 cases (1.7%)

AKTIVITAS PENGHAMBATAN PEMBENTUKAN BATU GINJAL (Antinefrolithiasis) EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus moschtus Medik) PADA TIKUS PUTIH JANTAN Triana Riandani Djamhuri; Yuliet Yuliet; Khildah Khaerati
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 1 (2016): (March 2016)
Publisher : Universitas Tadulako

Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW

PROFIL PENGGUNAAN OBAT PASIEN PENYAKIT KULIT DI POLIKLINIK KULIT DAN KELAMIN RSU ANUTAPURA PALU Fani Oktaviani; Alwiyah Mukaddas; Ingrid Faustine
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 1 (2016): (March 2016)
Publisher : Universitas Tadulako

Skin diseases, one type of diseases that is still very dominant occuring and becoming one public health problem in Indonesia, are caused by bacteria, viruses, fungi, parasite infestations or allergic reactions. They can be treated with various ways including topical, systemic and or intralesional routes. This study aimed to determine the drug use profile of patients with skin disease at Dermatology and Venereology Polyclinic in Anutapura General Hospital Palu using prospective method and data were descriptively presented. The results showed that from 98 patients, there was 53.06% male; 55.10% aged 41-65 years; and 27.55% housewifes and it was found that 100% of them had clinical manifestation of rash in which the most diagnosis of skin disease was Psoriasis vulgaris as much as 13.26%. Patients receiving 4-6 amount of drug variation were 68.37% that based on total frequency of the type of drugs used (381), the most class of therapy was topical corticosteroid anti-inflammatory drugs (23.10%), such as desoximetasone (18.11%); while based on frequency of the drug dosage forms (213), tablet was the most dominant one (43.19%). This results were in accordance with the Standards of Medical Care of Anutapura General Hospital Palu

UJI AKTIVITAS ANTIJAMUR INFUSA UMBI BAWANG PUTIH (Allium sativum L.) TERHADAP Candida albicans SERTA PROFIL KROMATOGRAFINYA Khusnul Diana
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 1 (2016): (March 2016)
Publisher : Universitas Tadulako

As traditional medicine, bawang putih or garlic ( Allium sativum L.) can cure as antibacterial and antifungal beside on can restorative as antihypertension, antacid, carminativa (in the dyspepsia), expectorancia and anticolesterol. This research was conducted in order to know the antifungal activity of infusion of Allium sativum against Candida albicans and to identify chemical component’s of this infusion. The antifungal activity was done by liquid dilution method. The MIC (Minimal Inhibitory Concentration) and MFC (Minimal Fungicidal Concentration) value were used as parameter to determine the antifungal activity. Concentration used in this reseach were 17,5%; 16,25%; 15%; 13,75% ; 12,5% dan 11,25% v/v for Candida albicans. The activity was done by incubating the infusion with fungal in CYG DS media of 37ºC for 18-24 hours. Identification of chemical component was carried out by paper chromatography and thin layer chromatography. The result showed that the MIC (Minimum Inhibitor Concentration) for Candida albicans could not be observed because the mixture was turbid. The MFC (Minimum Fungicidal Concentration) for Candida albicans was 15% v/v. The tube test and chromatogram showed that the infusion of Allium sativum contained flavonoid, and saponin.

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Contact Name
Muhammad Sulaiman Zubair

Contact Email
sulaiman_zubair80@yahoo.co.id

Phone
+6285242083654

Journal Mail Official
jurnalgalenika.farmasiuntad@gmail.com

Editorial Address
Jurusan Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Tadulako

Location
Kota palu,

Sulawesi tengah

INDONESIA

Abstract

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Muhammad Sulaiman Zubair

Contact Email sulaiman_zubair80@yahoo.co.id

Phone +6285242083654

Journal Mail Official jurnalgalenika.farmasiuntad@gmail.com

Editorial Address Jurusan Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Tadulako

Location Kota palu, Sulawesi tengah INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Muhammad Sulaiman Zubair

Contact Email
sulaiman_zubair80@yahoo.co.id

Phone
+6285242083654

Journal Mail Official
jurnalgalenika.farmasiuntad@gmail.com

Editorial Address
Jurusan Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Tadulako

Location
Kota palu,

Sulawesi tengah

INDONESIA