cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Muhammad Sulaiman Zubair
Contact Email
sulaiman_zubair80@yahoo.co.id
Phone
+6285242083654
Journal Mail Official
jurnalgalenika.farmasiuntad@gmail.com
Editorial Address
Jurusan Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Tadulako
Location
Kota palu,
Sulawesi tengah
INDONESIA
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)
Published by Universitas Tadulako
ISSN : 24427284     EISSN : 24428744     DOI : https://doi.org/10.22487/j24428744
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (E-ISSN: 2442-8744) (p-ISSN: 2442-7284), is an open access journal (print and e-journal) focusing on the scientific works in the field of Pharmacy and Pharmaceutical Science. The articles of this journal are published every six months, that is March and October (2 issues per year). This journal is developed by Department of Pharmacy, Faculty of Mathematics and Natural Science, Tadulako University and has been identified in Crossref with the DOI Number : 10.22487/j24428744. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) has been accredited by Kemenristekdikti as Sinta 3 starting from Volume 5 No 1 2019.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 6 Documents
 1 
Search results for , issue "Vol. 7 No. 3 (2021): (December 2021" : 6 Documents clear
Correlation of Metered Dose Inhaler Use Technique and Asthma Control Level in Asthma Patients at a Hospital in Bandung, West Java, Indonesia: Hubungan Ketepatan Penggunaan Metered Dose Inhaler dengan Tingkat Kontrol Asma pada Pasien Asma di Salah Satu Rumah Sakit di Bandung, Jawa Barat, Indonesia Widyastiwi, Widyastiwi; Nurilsyam, Tsania; Roseno, Mohammad; Farida Lhaksmiwati, Inne
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15643

Abstract

Background: Asthma is still a major health problem in global population, including Indonesia. Antiasthma drugs available in various dosage forms, including inhaler. However, several problems related to inhalation route were found due to its unique device form and spesific use technique. One of the major problems related to inhalation route is inappropriate use technique of inhaler device, which could lead to treatment failure. Therapy outcome can be measured through Asthma Control Test (ACT). Objectives: This study was aimed to evaluate correlation between metered dose inhaler (MDI) use technique and asthma control level in patients. Material and Methods: A cross-sectional analytic study was conducted in May - June 2021. Thirty patients who met inclusion criteria were enrolled in this study. Patients’ MDI use technique and asthma control level were evaluated using a valid and standardized questionnaire. Statistics analysis was performed to determine the correlation between MDI use technique and asthma control level. Results: This study showed that most of asthmatic patients were women in older age, with mild asthma severity for more than 10 years. The most prevalent medication used was Fenoterol HBr, followed by salbutamol, and salmeterol/fluticasone combination. Inappropriate MDI use was found in 70,0% patients, with major problem found in patients’ breathing technique before and during MDI use. Asthma control test was performed and showed that 90,0% of asthmatic patients involved in this study have an uncontrolled asthma. Statistical analysis using Pearson product-moment correlation test showed a positive correlation between proper use of MDI and asthma control level (r=0.425, p<0.05). Conclusions: Patient who properly use MDI may have a higher score in asthma control test, thus have a better control of asthma. This study emphasized pharmacist role as patient educator in ensuring appropriate inhaler use in order to achieve therapeutic goals.
Narrative Review: Implementation of Pharmaceutical Care in Hypertension in Indonesia: Tinjauan Naratif: Penerapan Asuhan Kefarmasian pada Hipertensi di Indonesia SImamora, Sarmalina; Akbar, Widyan Muchzadi; Mangunsong, Sonlimar
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15662

Abstract

Background: In the past, patient care was not a pharmacy orientation. Several developed countries have applied pharmaceutical care in the treatment of hypertension for years. However, it is still there. In Indonesia, the government issued guidelines for the care of hypertension medications for the first time in 2006. The stages are that pharmacists carry out assessments, prepare pharmaceutical service plans, then implement and monitoring. This study aims to examine the application of pharmaceutical care in hypertension in various articles published in Indonesia. Methods: This research is non-experimental research with a narrative review design. Articles were selected using the keywords pharmaceutical care, pharmacy care, pharmaceutical care and hypertension. Articles in national journals. The number of articles reviewed was 13 articles from 2014 to 2019. Results: The application of pharmaceutical care in hypertension in Indonesia has been carried out by pharmacists, especially in hospitals. The implementation stages are more focused on implementation and monitoring. Only 15% carried out the plan, and almost no carried out the assessment. Conclusion: The application of pharmacy in hypertension has not fully complied with the guidelines. Pharmacists have not assessed when they will start pharmaceutical care. Intervention is carried out with various models, such as leaflets, short messages sent and counselling. Results were monitored on the patient's knowledge, compliance and blood pressure. The result is an improvement, although some are not.
Antioxidant Screening and Sunscreen Activity of Nanocream of Purified Extract of Kenikir Leaves (ETDK) and Tampoi Fruit Peel Extract (EKBT): Skrining Antioksidan dan Aktivitas Tabirsurya Nanokrim Ekstrak Terpurifikasi Daun Kenikir (ETDK) dan Ekstrak Kulit Buah Tampoi (EKBT) Rahman, Ika Ristia; Kartikasari, Dian; Kurnianto, Erwan; Herdaningsih, Sulastri
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15663

Abstract

Background: UV lights are free radicals that can cause damage to the skin, such as redness, burning, pigmentation, and even cancer. Kenikir leaf purified extract (ETDK) and Tampoi fruit peel extract (EKBT) contain flavonoid compounds. Flavonoid compounds can be antioxidants and sunscreens due to the presence of chromophore groups that can absorb UV rays to reduce exposure to the skin. Objectives: This study aims to determine the antioxidant activity and the ability of sunscreen nano cream Purified extract of Kenikir leaves and Tampoi fruit peel extract. Material and metode: Nanocream is made with 3 ETDTK-EKBT combination formulas, II ETDK formulas, III EKBT formulas. The antioxidant activity test was carried out using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method and the sunscreen activity test using the UV-Vis spectrophotometric method to calculate the SPF value of the preparation (Mansur's method). Result: The results showed that the nano cream formula had a strong antioxidant activity with the per cent inhibition of formula I 78.28%, formula II 68.49%, and formula III 73.00%. The activity test results as a sunscreen formulation of purified extract nano cream from Kenikir leaves and nano cream from Tampoi fruit peel extract had extra protection ability with a sun-protecting factor value of 7 while the nano cream formula combined extract with an SPF value of 10 gave the maximum protection category. Conclusion: nano cream have potential as antioxidants and sunscreens.
Mangrove (Rhizophora sp.) Fruit Extract Inhibits Tumor Growth Factor (TGF)-β1 Expression in High Cholesterol Diet-Fed Rats: Ekstrak Buah Bakau (Rhizophora sp.) Menghambat Ekspresi Tumor Growth Factor(TGF)-β1 pada Tikus yang Mendapat Diet Tinggi Kolesterol Hamidy, Muhammad Yulis; Masdar, Huriatul; Winarto, Winarto
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15667

Abstract

Background: Atherosclerosis is a major finding in cardiovascular disease. One of the pro-fibrotic cytokines that play an important role in the atherosclerosis process is Tumor Growth Factor (TGF)-β1, where the presence of high TGF-β1 secretion due to hypercholesterolemia will trigger excessive collagen matrix formation. Objective: To analyze Rhizophora sp fruit extract effect on TGF-β1 expression in high cholesterol diet-fed rats. Material and Methods: Eighteen 10-week-old rats weighing 150-200 g were used in this study. These animals were grouped into 3 groups, each consisting of 6 rats. Group A (normal control) is a group of rats that received a normal diet. Group B (atherogenic control) received a diet that induces atherosclerosis (atherogenic diet). This diet contains 2% cholesterol, 5% goat fat, 0.2% cholic acid and standard diet up to 100%. Atherogenic diet was given for 3 days, and on the first day this group also received vitamin D3 700,000 IU/kg. Group C (treated), apart from receiving an atherogenic diet, was also given Rhizophora sp fruit extract 500 mg/kg body weight. The Rhizophora sp fruit extract effect on TGF-β1 expression was evaluated by immunohistochemical procedure. The area of ​​the expression is calculated using the ImageJ. Results: The results of this study indicate that the expression of TGF-β1 is higher in the group receiving the atherogenic diet than the normal control group (17.3 vs. 8.9; P=0.000). Rhizophora sp fruit extract reduced this expression remarkably (17.3 vs. 11.4; P=0.001). Conclusion: Rhizophora sp fruit extract inhibits the the expression of TGF-β1 in high cholesterol diet-fed rats.
Comparison of the Number of Bacterial Colonies Before and After Using Hand Sanitizer From Acacia Nilotica Leaf Extract : Perbandingan Jumlah Koloni Bakteri Sebelum Dan Sesudah Menggunakan Hand Sanitizer Dari Ekstrak Daun Acacia nilotica L. Jannah, Syarifah Miftahul El; Zuraida, Zuraida; Yulfianna, Desy; Aditia, Erie
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15670

Abstract

Background: Using hand sanitizers was an act of necessity during the Covid-19 pandemic. With this action, it is expected to control the number of bacterial colonies on the palms of the hands. One of the herbal ingredients that can inhibit the growth of germs is Acacia nilotica L-leaf extract so that it can be used as an active ingredient in hand sanitizer. Objective: To determine the number of bacterial colonies before and after using a hand sanitizer with the active ingredient of acacia leaf extract. Materials and Methods: The study used random sampling analysis before and after treatment. Acacia nilotica leaf ethanol extract formula 10%, 20% and 30%. Each concentration was used by 11 men and 11 women as a hand sanitizer with movements according to WHO standards and left for 30 seconds. Check the count of germs on hands before and after using hand sanitizer. Results: The highest decrease in the number of bacterial colonies was found at a concentration of 30% reaching 64.84% in men and 89.61% in women. There were differences in the ability to decrease the number of bacterial colonies from each concentration (P 0.003 < 0.005). Conclusion: Acacia nilotica L leaf extract can be a candidate for active hand sanitizer ingredients.
Correlation Between the Number of Drugs Prescribed and Potentially Inappropriate Medication (PIMS) Based on Beers Criteria in Geriatric Hypertension Outpatients at Dr. Soedomo Hospital in Trenggalek: Hubungan Jumlah Obat terhadap Potentially Inappropriate Medication (PIMS) Berdasarkan Beers Criteria pada Pasien Hipertensi Geriatri Rawat Jalan Rsud Dr. Soedomo Trenggalek Widyaningrum, Esti Ambar; PDW, Kumala Sari; Astuti, Lelly Winduhani; Suhartatik, Sri; Rimawati, Rimawati; Sari, Eka Kartika
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15671

Abstract

Background: Geriatric patients are elderly people who have various diseases and or problems as a result of diminished organ, psychological, social, economic, and environmental functioning and who require integrated health treatments from a multidisciplinary team. Uncontrolled hypertension can lead to complications such as stroke, CHD, and kidney failure. The more incidence of complications, causing the geriatrics to get more drugs (polypharmacy). Polypharmacy is one of the risk factors for the occurrence of Potentially Inappropriate Medication (PIMs) that often occurs in geriatric patients. The 2019 Beers Criteria is one of the clear criteria that can be used to determine the prevalence of PIMs in geriatric individuals. Objectives: The objective of this study was to see if there was a correlation between the number of drugs administered to hypertensive geriatric outpatients at Dr. Soedomo General Hospital in Trenggalek and the incidence of PIMs. This study employed an observational study with an analytical approach and retrospective. This study included a sample of 85 prescriptions for outpatient geriatric hypertension outpatient at Dr. Soedomo General Hospital in the period October - December 2020 taken using the purposive sampling technique. Data were analyzed using the C contingency coefficient correlation test. Results: 67,1% of prescriptions contained ≥ 5 kinds of drugs and 32,9% of prescriptions contained < 5 kinds of drugs. Based on the incidence of PIMs, there were 97.6% of prescriptions for PIMs and 2.4% of prescriptions without PIMs. The C contingency coefficient correlation test shows the correlation coefficient (r) of 0.216 with a positive direction and p-value = 0.041. Conclusions: The number of drugs has a significant correlation and can cause the incidence of PIMs in geriatric patients with weak correlation strength. Collaboration between pharmacists and doctors is needed to provide the best therapy to patients, to maximize the role of pharmacists in monitoring drug use in geriatric patients at Dr. Soedomo Hospital in Trenggalek.

Page 1 of 1 | Total Record : 6

 1 

Filter by Year

2021 2021


Reset
Filter By Issues
All Issue Vol. 11 No. 2 (2025): October 2025 Vol. 11 No. 1 (2025): (March 2025) Vol. 10 No. 2 (2024): (October 2024) Vol. 10 No. 1 (2024): (March 2024) Vol. 9 No. 2 (2023): (October 2023) Vol. 9 No. 1 (2023): (March 2023) Vol. 8 No. 2 (2022): (October 2022) Vol. 8 No. 1 (2022): (March 2022) Vol. 7 No. 3 (2021): (December 2021 Vol. 7 No. 2 (2021): (October 2021) Vol. 7 No. 1 (2021): (March 2021) Vol. 6 No. 2 (2020): (October 2020) Vol. 6 No. 1 (2020): (March 2020) Vol. 5 No. 2 (2019): (October 2019) Vol. 5 No. 1 (2019): (March 2019) Vol. 4 No. 2 (2018): (October 2018) Vol. 4 No. 1 (2018): (March 2018) Vol. 3 No. 2 (2017): (October 2017) Vol. 3 No. 1 (2017): (March 2017) Vol. 2 No. 2 (2016): (October 2016) Vol. 2 No. 1 (2016): (March 2016) Vol. 1 No. 2 (2015): (October 2015) Vol. 1 No. 1 (2015): (March 2015) More Issue