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All Journal Jurnal Farmasi Udayana Majalah Obat Tradisional BIOMA : Jurnal Biologi Makassar Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) BULETIN AL-RIBAATH Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Ilmiah Farmako Bahari Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Pharmacy Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmaceutical Sciences and Research (PSR) Journal of Pharmaceutical and Sciences. Jurnal Komunitas Farmasi Nasional Journal Pharmacy of Tanjungpura
Rahman, Ika Ristia
Akademi Farmasi Yarsi Pontianak
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETANOL DAN KLOROFORM BUAH SENGGANI (Melastoma malabathricum L.) DENGAN MENGGUNAKAN METODE PENANGKAP RADIKAL BEBAS DPPH (2,2-Diphenyl-1-picrilhidrazil) Dian Kartikasari; Ika Ristia Rahman; Syarifah Nurhayati
Jurnal Insan Farmasi Indonesia Vol 1 No 1 (2018)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Buah senggani diketahui mengandung senyawa antioksidan, masalah yang dihadapi adalah senyawa aktif yang terkandung dan seberapa besar aktivitas senyawa antioksidan yang terkandung didalam buah senggani. Untuk itu dilakukan uji fitokimia dan uji aktivitas antioksidan pada fraksi etanol dan kloroform buah senggani dengan metode penangkap radikal bebas DPPH dengan menggunakan pembanding vitamin C. Hasil uji fitokimia pada fraksi etanol mengandung senyawa metabolit sekunder golongan alkaloid, flavonoid triterpenoid dan steroid serta tanin, sedangkan pada fraksi kloroform mengandung senyawa metabolit sekunder golongan alkaloid, flavonoid dan steroid. Hasil uji aktivitas antioksidan fraksi etanol buah senggani di dapat nilai IC50 sebesar 2,31 ppm dan fraksi kloroform buah senggani di dapat sebesar 1,12 ppm. Dari hasil tersebut diketahui buah senggani memiliki aktivitas antioksidan yang sangat kuat.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN BUAS-BUAS (Premna serratifolia L.) ASAL KABUPATEN MELAWI PROVINSI KALIMANTAN BARAT DENGAN METODE DPPH Weni Puspita; Dina Yuspita Sari; Ika Ristia Rahman
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.532

Abstract

Buas Buas (Premna serratifolia L.) contains secondary metabolites of flavonoids, saponins, tannins and triterpenoids/steroids, where flavonoids are known to have antioxidant properties and counteract free radicals. Antioxidants are compounds that can fight toxic hazards and reduce cell damage to the body caused by free radical oxidation. The purpose of this study was to determine the antioxidant activity of ethanol extracts of buas-buas leaves was carried out by DPPH (2,2-diphenyl-1-picrylhydrazyl), using UV-Vis spectrophotometry at wavelength 518.40 nm with various concentrations of 10 ppm, 20 ppm, 30 ppm, 40 ppm and 50 ppm. The results showed that Buas Buas leaves (Premna serratifolia L.) had an antioxidant activity with IC50 values ??of 20.66 ug / mL.
KARAKTERISTIK DAN NILAI SUN PROTECTING FACTOR (SPF) KITOSAN DARI TULANG SOTONG (Sephia officinalis) Ika Ristia Rahman; Athiah Masykuroh
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.539

Abstract

Cuttlefish (sepia officinalis) have internal shells commonly called cuttlebones which produce more chitin than shrimp shells and crab skins. The purpose of this study was to determine the characteristics of chitosan from cuttlebone including the degree of deacetylation, water content, solubility, organoleptic test (color, odor, texture) as well as testing the value of chitosan protecting the sun protection factor. Chitosan is made in 3 stages, namely deproteination, demineralization, and deacetylation. Deproteination with 4% NaOH at 100 ° C for 60 minutes. Demineralization at room temperature using 1M HCl solution for 120 minutes. Deacetylation using 50% NaOH concentration at 100 ° C for 60 minutes. Chitosan characterization includes the degree of deacetylation, moisture content, solubility, organoleptic test (color, odor, texture). Testing the value of sun protection factor using a UV-VIS spectrophotometer read at wavelengths from 290 to 320 nm. Characteristics of chitosan produced according to chitosan standards used in industry with a deacetylation rate of 71%, yield 31%, moisture content of 0.93%, soluble in acetic acid2% solution, white odorless and powdery. Chitosan with a concentration of 3% gives the value of sun protecting factor 9 as a potential sunscreen that provides maximum protection power.
POTENSI SUSPENSI CANGKANG TELUR AYAM (Gallus domesticus) SEBAGAI ANTASIDA Dian kartikasari; Ika Ristia Rahman; Hairunisa Hairunisa; Abduh Ridha
Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i2.704

Abstract

Kalsium karbonat merupakan kadungan utama pada cangkang telur. Kalsium karbonat dibidang farmasi dapat digunakan sebagai antasida. Sediaan suspensi lebih cepat di serap dibandingkan dengan sediaan tablet kunyah. Penelitian ini bertujuan untuk mengetahui apakah suspensi cangkang telur ayam mampu bekerja sebagai antasida, dan untuk mengetahui konsentrasi efektif. Metode penelitian yang dilakukan adalah Kapasitas Penetralan Asam (KPA), dimana asam lambung disimulasikan menggunakan HCL. Sediaan suspensi yang dibuat dilakukan evaluasi fisik meliputi uji oraganoleptis, uji pH, uji homogenitas, uji viskositas, uji bobot jenis, uji sedimentasi. Hasil organoleptis yang didapat yaitu suspensi berwarna putih kekuningan berbau khas, berbentuk cair dan memiliki rasa yang manis. Sediaan suspensi homogen, pH suspensi formula 1, 2, dan 3 berturut turut adalah 7,37; 7,50 dan 7,37. Nilai viskositas suspensi formula 1,2, dan 3 berturut turut yaitu 10 cp; 14 cp dan 25 cp. Bobot jenis pada suspensi pada formula 1, 2, dan 3 berturut turut yaitu 1,12 g/ml; 1,14 g/ml dan 1,17 g/ml. Hasil uji sedimentasi menunjukkan terjadi sedimentasi pada formula 3. Nilai KPA formula 1,2 dan 3 berturut turut yaitu 9,92 mEq, 9,87 mEq, dan 10,08 mEq
FORMULASI LOTION EKSTRAK TERPURIFIKASI DAUN KENIKIR (Cosmos caudatus Kunth). Erwan Kurnianto; Ika Ristia Rahman; Dian Kartikasari; Hairunnisa Hairunnisa
Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i2.830

Abstract

Kenikir leaves (Cosmos caudatus Kunth) is a plant that is used as a vegetable and ornamental plant. Kenikirleaves contain flavonoid, phenol, diterpene, and ascorbic acid phytochemicals. The phytochemical content of kenikir leaves has antioxidant activity. The preparation widely used in applying antioxidants is lotion because of its easy use. This study aims to formulate a lotion from the purified extract of kenikir leaves by varying the extract 0.1%, 0.25% and 0.5%. The lotion base used was VCO, Tween 80, PEG 400, Aquadest. The physical characteristics evaluated were organoleptic, homogeneity, pH, spreadability, and emulsion type. From the results test, purified extract lotion of kenikir leaves gave a green color, characteristic smell of the extract, homogeneous, pH value according to lotion requirements, dispersion according to the standard range of 5-7cm, emulsion type of lotion oil in water.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL KULIT BUAH TAMPOI (Baccaurea macrocarpa) Ika Ristia Rahman
Jurnal Ilmiah Pharmacy Vol 8, No 2 (2021)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v8i2.338

Abstract

Buah tampoi merupakan buah hutan tropis yang pemanfaatannya hanya pada daging buah yang dikonsumsi. Pemanfaatan kulit buah Tampoi belum dilakukan secara maksimal. Ekstrak kulit buah tampoi mengandung senyawa metabolit sekunder seperti alkaloid, flavonoid, fenol, tannin dan saponin. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri pada bakteri E. coli, S. aureus dan P. acne dari ekstrak etanol kulit buah tampoi dengan metode disk diffusion.  Hasil pengujian aktivitas antibakteri ekstrak etanol kulit buah tampoi, pengujian pada bakteri E. coli, S. aureus dan P. acne, dilihat dari diameter daya hambat yang diberikan kulit buah tampoi memiliki potensi sebagai antibakteri. Semakin besar konsentrasi ekstrak kulit buah tampoi yang digunakan, semakin besar diameter daya hambat.
Keamanan Hair Tonic Ekstrak Etanol, Fraksi Etanol, dan Fraksi Kloroform-Metanol dari Kayu Secang (Caesalpinia sappan L.) dengan Metode Uji Iritasi Primer dan HET-CAM Dina Yuspita Sari; Ika Ristia Rahman
Jurnal Farmasi Udayana Vol. 10, No 2, Tahun 2021
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2021.v10.i02.p08

Abstract

Hair tonic is a hair care cosmetic to reduce hair loss, stimulate, and increase hair volume. Secang wood (Caesalpinia sappan L.) has the potential to be developed as an active substance in hair tonic products because it contains flavonoids, polyphenols, including brazilin which are used to treat damage hair. To ensure the safety of hair tonic products, safety tests are required, including skin and eye irritation tests. This study aims to determine the safety of hair tonic formula of ethanol extract, ethanol fraction, and chloroform-methanol fraction from sappan wood. Ethanol extract, ethanol fraction, and chloroform-methanol fraction of sappan wood were formulated into hair tonic preparations. The hair tonic safety test includes: primary irritation test and eye irritation test using HET-CAM method. Based on the primary irritation test, the score of erythema and edema on the skin obtained a PII value of 0 (non-irritating category). The HET-CAM test on the three hair tonic formulas, positive control and negative control, showed that the positive control (lactic acid) resulted in an irritation score of 9.51 (strong irritation category); negative control (NaCl 0.9%) and the three hair tonic formulas had an irritation score of 0 (no irritation category). This indicates that the hair tonic formula from ethanol extract, ethanol fraction, and chloroform-methanol fraction of sappanwood is not irritating and safe to use. Keywords: HET-CAM, primary irritation test, sappan wood
The Spectometric Quantification of Total Content of Flavonoid, Phenol, and Alkaloid in Kesum leaf (Polygonum minus Huds) from West Borneo with Methanol and Ethanol Solvent Dian Kartikasari; Ika Ristia Rahman; Heni Puspasari; Abduh Ridha
Majalah Obat Tradisional Vol 27, No 1 (2022)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.68497

Abstract

Kesum (Polygonum minus Huds) is one of the typical plants that grow in West Borneo. The Kesum leaves are the part which is mostly used. Kesum leaves contain a lot of phytochemical compounds. This study quantitatively determined the total phenolic, flavonoid, and alkaloid contents in methanol and ethanolic extract of Polygonum minus Huds leaves using a spectrophotometric method. The samples were extracted by maceration. The content was determined by using a UV-Vis spectrophotometer. Based on the assay result, the methanol extract contained a total of phenolic 49.351±0.430 ppmEAG (equivalent to gallic acid); total of flavonoids 44.128±0.116ppmEQ (quercetin equivalent); total of alkaloids 356,798±1,004ppmEP (piperine equivalent). The 96% ethanol extract contained total of phenol 46,196±0.329ppmEAG; total of flavonoids 34,969±0.116ppmEQ; total of alkaloids 183.525±0.766ppmEP. The 70% ethanol extract contained total of phenol 64.189+0.215ppmEAG; total of flavonoids 27.834±0.158ppmEQ; total of alkaloids 432,947±1,533ppmEP. The ethanol extract 50% contained total of phenol 67,343±0.164ppmEAG; total of flavonoids 26.063±0.158ppmEQ; total of alkaloids 679,142±2,525ppmEP. All of the results are preliminary data for further research, especially for the isolation of compounds with specific targets or for utilization as main ingredients for traditional medicine.
POTENSI TABIR SURYA EKSTRAK ETANOL DAUN MATOA (POMETIA PINNATA) DENGAN VARIASI KONSENTRASI PELARUT Erwan Kurnianto; Ika Ristia Rahman
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.537 KB) | DOI: 10.36387/jiis.v7i1.835

Abstract

Secondary metabolite compounds that have potential as sunscreens are flavonoids with chromophore groups. Flavonoid compounds are found in the matoa plant (Pometia pinnata). This study aimed to determine the possibility of matoa extract sunscreen with various solvent concentrations. Variations in the concentration of ethanol used were 50%, 70% and 96% ethanol. Matoa leaf simplicia was macerated with each solvent for 3×24 hours. Then the macerate was concentrated using a rotary evaporator. The viscous extract was tested for flavonoid qualitative using the staining method and tested for sunscreen potency using UV-Vis spectrophotometry with absorbance readings at a 290-320 nm wavelength. The potential for sunscreen in the form of an spf value is calculated using the Mansur equation. The results showed that the ethanolic extract of matoa leaves contained flavonoid. Matoa leaf extract has sunscreen potential. The highest SPF value in the extract with 70% ethanol solvent provides ultra protection value.
UJI FITOKIMIA PADA DAUN KESUM (Polygonum minus Huds.) DARI KALIMANTAN BARAT Dian Kartikasari; Ika Ristia Rahman; Abduh Ridha
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.912

Abstract

Kesum leaves are one of the plants that are widely available in West Kalimantan and are used by the community as vegetables or cooking spices. Research on the chemical content of kesum leaves has been carried out by several researchers, but research on whether there are differences in the chemical content obtained from the extraction with several types of solvents in kesum leaves has not been carried out. Therefore, in this study, the chemical content of kesum leaves will be tested. The method used is to test the presence of chemical compounds by phytochemical screening on several kesum leaf extracts using different solvents, namely 70% ethanol, 50% ethanol, 96% ethanol and methanol. The observations obtained were then analyzed descriptively and presented in tabular form. The results of the phytochemical screening test showed that the kesum leaf extracted in 70% ethanol, 50% ethanol, 96% ethanol, and methanol solvent contained phenols, flavonoids, saponins, and tannins. Moreover, extract of ethanol 70% and ethanol 50%, also contain terpenoids amd alkaloids, which were not detected on ethanol 96% and methanol extract.
Co-Authors -, Herlyana Abduh Ridha Anggraini Putri Rusdiana Dewi Annisa Fatmawati Athiah Masykuroh Dian Kartikasari Dian Kartikasari Dina Yuspitasari Geby Ariskha Hadi Kurniawan Hairunisa Hairunisa Hairunnisa Hairunnisa Hairunnisa Hairunnisa Hairunnisa Hairunnisa Hairunnisa Hairunnisa Hamdi, Ananda Heni Puspasari Herdaningsih, Sulastri Herliwisandi, Ferry Ika Kumalasari Kumalasari, Ika Kurnianto, Erwan Nine Okta Meliadlina Nurkhasanah Nurkhasanah Nurkhasanah, Puspita, Weni Putry Fajaria Hardiani Rifki Fahmi Riyanti, Tiara Ropiqa, Meri Sari, Dina Yuspita Syarifah Nurhayati Tri Yanuarto Yusmanto, Eko Yohanes