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Jurnal Surya Medika

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Published by Universitas Muhammadiyah Palangkaraya

ISSN : 24607266 EISSN : 26552051 DOI : -

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

The publication of Jurnal Surya Medika certainly participates in disseminating the results of research and review of science and technology development conducted by lecturers and researchers especially from UM Palangkaraya and other universities. This edition contains 17 articles consisting of Pharmacy, Medical Laboratory Technology, and another Health Science topics.

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Articles 722 Documents

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Uji Aktivitas Spermisida Ekstrak Etanol Biji Pare Gajih (Momordica charantia L) terhadap Sperma Manusia secara In Vitro Nurul Chusna
Jurnal Surya Medika (JSM) Vol 1 No 2 (2016): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Biji pare gajih (Momordica charanti, L) dalam pengobatan tradisional digunakan untuk radang tenggorokan, batuk, demam, pingsan karena udara panas, nyeri haid. Kandungan kimia dari biji pare gajih yaitu flavonoid, saponin dan polifenol. Dimana flavonoid pada biji yang digunakan sebagai antispermatogenesis. Penelitian ini bertujuan untuk mengetahui apakah ekstrak soxhletasi biji pare gajih memiliki aktivitas spermisida terhadap sperma manusia dan menentukan kadar letal median (LC₅₀). Uji aktivitas spermisida dilakukan dengan cara in vitro dengan konsentrasi ekstrak 1.000, 2.000, 3.000, 4.000, 5.000, 10.000, 20.000, 30.000, 40.000, 50.000 μg/ml. LC₅₀ ditentukan dengan menggunakan metode persamaan garis. Analisa statistik dengan menggunakan anava 1 arah dengan taraf kepercayaan 95%. Ekstrak biji pare gajih dapat digunakan sebagai spermisida (berbeda bermakna terhadap kontrol negatif pada taraf kepercayaan 95%) dengan LC₅₀ probandus I sebesar 15.138,25 μg/ml, probandus II sebesar 9.164,69 μg/ml, dan probandus III sebesar 8.294,17 μg/ml.

Pengaruh Penambahan Aerosil terhadap Sifat Fisik Suppositoria Ekstrak Daun Bayam Duri (Amaranthus spinosus, Linn) dengan Basis Berlemak (oleum cacao) Evi Mulyani
Jurnal Surya Medika (JSM) Vol 1 No 2 (2016): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Bayam duri (Amaranthus spinosus Linn) merupakan tanaman dengan kandungan kuersetin yang digunakan masyarakat Indonesia sebagai obat wasir dengan cara direbus, kemudian air rebusan digunakan untuk mencuci dan mengompres bagian anus. Penggunaan dengan cara tersebut tidak efisien dan tidak efektif, sehingga harus diformulasikan dalam sediaan yang cocok yaitu suppositoria dengan basis berlemak (Oleum cacao). Karena oleum cacao mempunyai viskositas rendah dan sukar bercampur dengan ekstrak maka perlu ditambahkan aerosil, dimana aerosil merupakan zat tambahan yang digunakan sebagai pendispersi dan mampu meningkatkan viskositas. Sehingga penelitian ini bertujuan untuk mengetahui bagaimana pengaruh penambahan aerosil terhadap sifat fisik sediaan suppositoria ekstrak daun bayam duri dengan basis berlemak (oleum cacao). Ekstrak daun bayam duri dibuat menggunakan metode soxhletasi dengan pelarut etanol dan di lakukan penguapan dengan rotary evaporator sehingga diperoleh ekstrak kental, kemudian di identifikasi kandungan zat aktifnya (kuersetin) dengan metode KLT densitometri. Pembuatan suppositoria ekstrak daun bayam duri menggunakan metode peleburan dengan penambahan aerosil 1% (FI), 2% (FII), dan 3% (FIII). Suppositoria yang dihasilkan kemudian diuji sifat fisiknya seperti keseragaman bobot, kekerasan, suhu leleh, dan waktu leleh. Data kemudian di analisis secara teoritis dengan membandingkan hasil uji dengan persyaratan yang sudah ditentukan dalam literatur dan secara statistik menggunakan one way ANOVA dan uji Tukey dengan taraf kepercayaan 95%. Hasil penelitian menunjukan bahwa semua formula suppositoria ekstrak daun bayam duri memenuhi persyaratan sifat fisik kecuali FI (1%) yang mempunyai nilai kekerasan < 1,8 kg (1,73 kg). Hasil analisis secara statistik menunjukan bahwa penambahan aerosil berpengaruh terhadap kekerasan suppositoria kecuali FI (1%) dan FII (2%), penambahan aerosil juga berpengauh pada suhu leleh FI (1%) dan FIII (2%), sedangkan pada waktu leleh penambahan aerosil berpengaruh terhadap semua formula.

Pengaruh Jenis Media dengan Hormon Tumbuh NAA-BAP terhadap Pertumbuhan dan Kandungan Flavonoid Kalus Daun Echinaceae purpurea (L.) Moench Guntur Satrio Pratomo
Jurnal Surya Medika (JSM) Vol 1 No 2 (2016): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Echinaceae purpurea (L.) Moench merupakan tanaman obat yang mempunyai khasiat salah satunya imunomodulator dan imunostimulan. Tanaman ini mengandung metabolit sekunder salah satunya yaitu falvonoid. Penelitian ini bertujuan untuk mengetahui kemampuan media dalam menginduksi kalus dan mempengaruhi kandungan flavonoid dalam kalus daun E. purpurea (L.) Moench. Eksplan adalah daun E. purpurea (L.) Moench yang segar, sehat, dan tidak terlalu tua. Sterilisasi eksplan dilakukan dengan Dithane M-45 2 %, dengan penambahan Tween 80, Agrept 20/WP 2 % dengan penambahan Tween 80, alkohol 70 %, dan Bayclin® 10 %. Penanaman eksplan dilakukan dengan menggunakan media MS, ½ MS, dan Gamborg dengan penambahan kombinasi zat pengatur tumbuh NAA dan BAP masing-masing konsentrasi 1 ppm. Evaluasi kalus dilakukan terhadap prosentase keberhasilan pembentukan, waktu induksi, dan rata-rata berat kalus. Analisa flavonoid dalam kalus dilakukan secara kualitatif dengan reaksi warna, tes Wilstater Cyanidin, Kromatografi kertas , dan Kromatografi Lapis Tipis, serta semikuantitatif dengan KLT-Densitometri Hasil penelitian menujnukkan bahwa jenis media mempengaruhi keberhasilan pertumbuhan kalus dan kandungan flavonoid kalus daun E. purpurea (L.) Moench. Media Gamborg berpengaruh paling baik dalam menginduksi kalus sedangkan media ½ MS berpengaruh paling baik terhadap kandungan flavonoid di banding jenis media lain.

Gambaran Penggunaan Obat Antihipertensi pada Pasien Preeklampsia di Instalasi Rawat Inap Rumah Sakit Bhayangkara Kota Palangka Raya Tahun 2016 Syahrida Dian Ardhany
Jurnal Surya Medika (JSM) Vol 4 No 2 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Preeclampsia and eclampsia are the second rank cause of maternal mortality, and the first is bleeding. Therefore, the initial diagnosis of preeclampsia, which is the beginning of eclampsia, and its treatment needs to be immediately implemented to reduce maternal and child mortality. This study aims to know the description of antihypertensive preeclampsia in Bhayangkara Hospitals of Palangka Raya to review of an aspect of the accurate indication, the right drug, right patient, and the right dose of the reference JNC 7. This type of research is nonexperimental research. The study was done by observation which the data was taken retrospectively and analyzed by descriptive non-analytic. The result showed that the type of drug used was 80% of methyldopa, 60 % nifedipine, MgSO4 60% and of evaluation of drug use in Bhayangkara Hospitals of Palangka Raya in 2016 did not find any indication, drug, dose, and patient that not right.

Evaluasi Perencanaan Obat dan Perbekalan Farmasi di Depo Pusat Jantung Terpadu Rumah Sakit Umum Haji Adam Malik Medan Ismedsyah Ismedsyah; Sri Rahayu
Jurnal Surya Medika (JSM) Vol 4 No 2 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Planning is an activity to determine the type and amount of medicine as needed. The weak plan is marked by the occurrence of emptiness or accumulation of drugs. The purpose of this study is to evaluate the medical planning and pharmacy supplies at Depo PJT RSUP HAM Medan period 2016-2017. The method of research is non-experimental research with a descriptive approach. Data collection used in this study is observations. Observations in question are analyzed records at Depo PJT RSUP HAM Medan 2016-2017. Research results show that the availability of funds in 2016 amounted to 102% and 2017 amounted to 101%; this has met the predetermined standard value of 100%. The percentage of absorption of funds provided in 2016 was 98%, and 2017 was 4.7%. The conclusion of this research show percentage availability funds in 2016 have been meet value standards that have been set in Regulation of the Minister of Health of Republic of Indonesia Number 72 of 2016. Deviations in Depo PJT planning RSUP Human Terrain 2016 and 2017 is still within the limit values limit deviation planning that is between 20-30%.

Uji Daya Hambat Ekstrak Etanol Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) terhadap Bakteri Staphylococcus aureus Susi Novaryatiin; Ahmad Ramli; Syahrida Dian Ardhany
Jurnal Surya Medika (JSM) Vol 4 No 2 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Dayak Onion is a typical plant of Central Kalimantan. This plant has been traditionally used by the Dayak community as traditional medicine. Empirically, Dayak Onion bulbs are known to have properties to treat boils or skin diseases. The purpose of this study was to determine the ability of inhibition of Dayak Onion ethanol extract in inhibiting Staphylococcus aureus bacteria and to determine the effectiveness of the inhibition of Dayak Onion ethanol extract and concentration that could inhibit the growth of Staphylococcus aureus bacteria. This research was carried out by testing the antibacterial activity of Dayak Onion extract at levels of 1%, 5%, 10%, and 15% using the Disc Diffusion (Kirby-Bauer) method by using disc paper. The results showed that Dayak Onion ethanol extract was able to inhibit the growth of Staphylococcus aureus and effectively inhibited the growth of Staphylococcus aureus at concentrations of 1%, 5%, 10%, and 15% with inhibitory zones of 14.3 ± 2.5 mm ; 16.6 ± 1.7 mm; 16.2 ± 2.0 mm; and 18.0 ± 1.7 mm.

In-Vitro Study of Antioxidant Activities from Ethanol Extracts of Akar Kuning (Arcangelisia flava) Suratno Suratno; Muhammad Ikhwan Rizki; Mohammad Rizki Fadhil Pratama
Jurnal Surya Medika (JSM) Vol 4 No 2 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

This study aims to determine the antioxidant activity of akar kuning (Arcangelisia flava) stem extract from Central Kalimantan using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. This research includes extraction of simplicia and test of antioxidant activity by DPPH method. Based on the analysis of antioxidant activity on ethanol extract from yellow root plant stem IC50 values of 136.81 ppm were obtained. This IC50 value indicates the antioxidant strength of the yellow root plant stems including in the moderate category. Further research on antioxidant activity in the fraction of akar kuning stems needs to be done to determine the composition of the antioxidant compounds in each solvent.

Sistematik Review: Kriteria dan Peran Pengawas Menelan Obat Pasien Tuberculosis di Indonesia Fina Ratih Wira Putri
Jurnal Surya Medika (JSM) Vol 4 No 2 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Indonesia falls into the category of countries with the highest TB case burden. This number will continue to increase if the number of TB patient care is not implemented properly. Non- compliance with treatment is a separate problem in the success of TB elimination. The role of Supervisor for Drug Swallowing/Pengawas Menelan Obat (PMO) is one of the factors that support the success of TB treatment. The purpose of this study was to determine the criteria and role of supervisors to swallow drugs in tuberculosis patients in Indonesia. Two article search engines were used, namely GARUDA (Garba Rujukan Digital) and Neliti. There are 14 types of research identified, with details of 10 quantitative studies and 4 qualitative studies. The expected criteria of the Supervisor for Drug Swallowing/Pengawas Menelan Obat (PMO) are over 17 years old, female, not working, minimum high school education having kinship relations, living at home, and if the supervisor swallows drugs is a health worker then has better knowledge about tuberculosis treatment and empowerment of TB patients to form a self group. The role of Supervisor for Drug Swallowing/Pengawas Menelan Obat (PMO) in Indonesia includes ensuring patients swallow drugs every day, become educators, accompany control patients to health care centers, remind patients to check recurrent phlegm, provide moral support to patients, take patients to health care centers if drug side effects occur, improve preventive behavior and increase body weight.

Daya Hambat Air Kelapa (Cocos nucifera) terhadap Pertumbuhan Bakteri Salmonella typhi dan Escherichia coli Fera Sartika
Jurnal Surya Medika (JSM) Vol 4 No 2 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Coconut products are known to have anti-bacterial activity. One product of coconut is coconut water. Coconut water has benefits in food processing, especially for health. Coconut water contains tannin or antidote (anti-poison) which is antibacterial which will inhibit bacterial growth. This study aims to determine the antimicrobial effects of coconut water by testing the inhibition of Salmonella typhi and Escherichia coli bacteria. This type of research uses experimental or experimental methods. Before the inhibitory test is carried out, phytochemical tests of coconut water are carried out such as flavonoids, alkaloids, tannins, saponins, and steroids. The results showed that coconut water does not contain the chemical compounds of flavonoids, alkaloids, tannins, saponins, and steroids. The results of the inhibitory test indicate that coconut water cannot inhibit the growth of Salmonella typhi and Escherichia coli bacteria.

Penentuan Nilai Sun Protection Factor secara In Vitro pada Ekstrak Etanol Akar Kalakai (Stenochlaena palustris Bedd) dengan Metode Spektrofotometer UV-Vis Rabiatul Adawiyah
Jurnal Surya Medika (JSM) Vol 4 No 2 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

The sunscreens or Sun Protecting Agent is the materials protecting the skin from the exposure to ultraviolet (UV) rays. Amount of Sun Protection Factor shows how many times the subject skin protection can be multiplied under the sun rays without erythema occurs. Kalakai contains some bio-active substance like phenol, flavonoid, alkaloid and terpenoid family which are proven as a very effective antioxidant. The purpose of this research was to determine the concentration of ethanol extract of kalakai root which has the potential as a sunscreen based on the Sun Protection Factor (SPF) parameter. Determination of SPF amount was carried out in vitro by UV-VIS spectrophotometer at a concentration of 50 ppm, 100 ppm, 150 ppm, 200 ppm, 250 ppm, 300 ppm, and 350 ppm with a wavelength of 290-320 nm. The result showed that kalakai root ethanol extract indicated potential as a sunscreen at a concentration of 300 ppm and 350 ppm obtained SPF values respectively 11 and 14 classified as sunscreens with extreme ability levels.

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Mohammad Rizki Fadhil Pratama

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Kota palangkaraya,

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