Garuda - Garba Rujukan Digital

HUBUNGAN JUMLAH OBAT YANG DIRESEPKAN DENGAN POTENSIAL PENGGUNAAN OBAT YANG TIDAK TEPAT PADA PASIEN PENYAKIT GINJAL KRONIS DI RS PKU MUHAMMADIYAH YOGYAKARTA Mulyani, Evi; Darmawan, Endang; Mustofa, Mustofa
Pharmaciana Vol 5, No 2 (2015): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Age-related decrease of physiological function caused some healt problem in elderly, so the problem of treatment in the elderly is also not uncommon found as polypharmacy and Potentially Inappropriate medication (PIMs). The purpose of this study to determine the relationship of the number of drug prescribed with PIMs in elderly patients with CKD in PKU Muhammadiyah Yogyakarta Hospital. PIMs identification by STOPP criteria, while the number of drugs prescribed seen by drugs control books. To assess the patients medical history by interviews and search records. Patient characteristics were analyzed descriptively, correlations between variables were analyzed with chi square test. From 53 samples, PIMs identified 17% and average one sample got one PIMs, while of the 410 drugs that prescribed average patient receivingÂ 8 drugs (> 6). Bivariate test results showed that no significant relationship between the number of drug prescribed with PIMs.

Tingkat Kepuasan Pasien terhadap Kualitas Pelayanan di Instalasi Farmasi Rumah Sakit Islam PKU Muhammadiyah Palangkaraya Evi Mulyani
Jurnal Surya Medika (JSM) Vol 2 No 2 (2017): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Penelitian ini bertujuan untuk mengetahui tingkat kepuasan pasien terhadap kualitas pelayanan di Instalasi Farmasi Rumah Sakit Islam PKU Muhammadiyah Palangkaraya berdasarkan lima dimensi kualitas jasa. Metode penelitian ini bersifat deskripstif dengan jumlah populasi 700 orang. Jumlah sampel pada penelitian ini sebanyak 90 orang. Data dikumpulkan menggunakan kuesioner tertutup yang berisi beberapa pernyataan. Kuesioner dibagikan langsung kepada 90 orang responden yaitu pasien rawat jalan/pendamping pasien rawat jalan, dalam hal ini pendamping pasien rawat jalan adalah orang yang menemani/mengantarkan pasien rawat jalan yang menerima pelayanan farmasi di Instalasi Farmasi Rumah Sakit Islam PKU MuhammadiyahPalangkaraya. Pengambilan sampel pada penelitian ini menggunakan purposive sampling. Analisis data yang digunakan dalam penelitian ini menggunakan format jawaban Skala Likert. Dari hasil penelitian yang diperoleh, tingkat kepuasan pasien terhadap kualitas pelayanan farmasi berdasarkan lima dimensi kualitas jasa yang dikemukakan oleh Parasuranman, Zeithmal, dan Berry adalah Dimensi bukti langsung (Tangible) 76,1% yang masuk dalam kategori puas, Kemampuan (Reability) 73,3% masuk dalam kategori puas, Daya tanggap (Responsivnes) 75,7% dalam kategori puas, Jaminan (Assurance) 72,2% masuk dalam kategori puas, serta dimensi Perhatian (Emphaty) 74,3% dalam kategori puas.

Pengaruh Penambahan Aerosil terhadap Sifat Fisik Suppositoria Ekstrak Daun Bayam Duri (Amaranthus spinosus, Linn) dengan Basis Berlemak (oleum cacao) Evi Mulyani
Jurnal Surya Medika (JSM) Vol 1 No 2 (2016): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Bayam duri (Amaranthus spinosus Linn) merupakan tanaman dengan kandungan kuersetin yang digunakan masyarakat Indonesia sebagai obat wasir dengan cara direbus, kemudian air rebusan digunakan untuk mencuci dan mengompres bagian anus. Penggunaan dengan cara tersebut tidak efisien dan tidak efektif, sehingga harus diformulasikan dalam sediaan yang cocok yaitu suppositoria dengan basis berlemak (Oleum cacao). Karena oleum cacao mempunyai viskositas rendah dan sukar bercampur dengan ekstrak maka perlu ditambahkan aerosil, dimana aerosil merupakan zat tambahan yang digunakan sebagai pendispersi dan mampu meningkatkan viskositas. Sehingga penelitian ini bertujuan untuk mengetahui bagaimana pengaruh penambahan aerosil terhadap sifat fisik sediaan suppositoria ekstrak daun bayam duri dengan basis berlemak (oleum cacao). Ekstrak daun bayam duri dibuat menggunakan metode soxhletasi dengan pelarut etanol dan di lakukan penguapan dengan rotary evaporator sehingga diperoleh ekstrak kental, kemudian di identifikasi kandungan zat aktifnya (kuersetin) dengan metode KLT densitometri. Pembuatan suppositoria ekstrak daun bayam duri menggunakan metode peleburan dengan penambahan aerosil 1% (FI), 2% (FII), dan 3% (FIII). Suppositoria yang dihasilkan kemudian diuji sifat fisiknya seperti keseragaman bobot, kekerasan, suhu leleh, dan waktu leleh. Data kemudian di analisis secara teoritis dengan membandingkan hasil uji dengan persyaratan yang sudah ditentukan dalam literatur dan secara statistik menggunakan one way ANOVA dan uji Tukey dengan taraf kepercayaan 95%. Hasil penelitian menunjukan bahwa semua formula suppositoria ekstrak daun bayam duri memenuhi persyaratan sifat fisik kecuali FI (1%) yang mempunyai nilai kekerasan < 1,8 kg (1,73 kg). Hasil analisis secara statistik menunjukan bahwa penambahan aerosil berpengaruh terhadap kekerasan suppositoria kecuali FI (1%) dan FII (2%), penambahan aerosil juga berpengauh pada suhu leleh FI (1%) dan FIII (2%), sedangkan pada waktu leleh penambahan aerosil berpengaruh terhadap semua formula.

Studi In Vitro: Efek Anti Kolesterol Ekstrak Daun Rambusa (Passiflora foetida L) Evi Mulyani
Jurnal Surya Medika (JSM) Vol 4 No 2 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

The Rambusa plant (Passiflora foetida L) is known to contain compounds for various treatments, empirically the people in Indonesia, especially Central Kalimantan, use the leaves of rambusa known as the cemot plant to reduce cholesterol levels in the blood. Chemically, cholesterol is a complex compound produced by the body with various functions, including producing sex hormones, adrenal cortex hormones, vitamin D, and the production of bile salts that help the intestines to absorb fat. So, if the dose is right or reasonable, the role of cholesterol in the body will be optimal. The purpose of this study was to determine the effect of anticholesterol in rambusa leaf extract. This study is an experimental study. The anticolesterol effect was tested by the modified enzymatic endpoint cholesterol method. The leaf extract of Rambusa was made with a concentration of 0.5 mg/ml, 1 mg/ml and 1.5 mg/ml as a positive control (multiplier) using simvastatin which was then reacted with reagent R1 and read the results using a photometer and UV-spectrophotometer. Vis with a wavelength of 546 nm. The measurement results using a photometer showed standard cholesterol levels (control negative) 200 mg/dl, positive control 195 mg/dl, 144 mg/dl (extract 0.5 mg/ml), 108 mg/dl (extract 1 mg/ml) and 103 mg/dl (extract 1.5 mg/ml). While the measurement of cholesterol absorbance and concentration using a UV-Vis spectrophotometer at a wavelength of 546 nm 0.179±159.8 mg/dl (Control positive), 0.123±109.8 mg/dl (extract 0.5 mg/ml), 0.110±98.2 mg/dl (extract 1 mg/ml), and 0.109±97.3 mg/dl (extract 1.5 mg/ml). As a conclusion, Rambusa leaf extract can reduce cholesterol levels in vitro.

Formulasi Sediaan Krim Antiinflamasi Ekstrak Etanol Daun Rambusa (Passiflora foetida L) Evi Mulyani; Halida Suryadini; Rizka Rahmadina Putri
Jurnal Surya Medika (JSM) Vol 7 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i2.3218

Rambusa (Passiflora foetida L) is a medicinal plant that is widely found in various regions in Indonesia, including in Central Kalimantan. Rambusa is empirically used as an antibacterial and anti-inflammatory. Previous research has shown that the content of Rambusa (Passiflora foetida Linn) leaves from Central Kalimantan is one of the steroids which has anti-inflammatory properties. The purpose of this study was to determine whether the ethanol extract of rambusa leaves can be processed into anti-inflammatory cream preparations and to determine the results of physical tests, namely organoleptic tests, homogeneity tests, dispersibility tests, and pH tests. This research was conducted by the smelting method. The results showed that the three creams of ethanol extract of rambusa leaf (Passiflora foetida L) had met the requirements for physical properties of homogeneity, spreadability, and pH.

HUBUNGAN JUMLAH OBAT YANG DIRESEPKAN DENGAN POTENSIAL PENGGUNAAN OBAT YANG TIDAK TEPAT PADA PASIEN PENYAKIT GINJAL KRONIS DI RS PKU MUHAMMADIYAH YOGYAKARTA Evi Mulyani; Endang Darmawan; Mustofa Mustofa
Pharmaciana Vol 5, No 2 (2015): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Age-related decrease of physiological function caused some healt problem in elderly, so the problem of treatment in the elderly is also not uncommon found as polypharmacy and Potentially Inappropriate medication (PIMs). The purpose of this study to determine the relationship of the number of drug prescribed with PIMs in elderly patients with CKD in PKU Muhammadiyah Yogyakarta Hospital. PIMs identification by STOPP criteria, while the number of drugs prescribed seen by drugs control books. To assess the patient's medical history by interviews and search records. Patient characteristics were analyzed descriptively, correlations between variables were analyzed with chi square test. From 53 samples, PIMs identified 17% and average one sample got one PIMs, while of the 410 drugs that prescribed average patient receivingÂ 8 drugs (> 6). Bivariate test results showed that no significant relationship between the number of drug prescribed with PIMs.

Formulasi dan Evaluasi Gel Topikal Antibakteri Fraksi Aktif Akar Kuning (Arcangelisia flava Merr.) Evi Mulyani; Suratno Suratno; Mohammad Rizki Fadhil Pratama
Jurnal Pharmascience Vol 7, No 1 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i1.8081

ABSTRAK Akar kuning (Arcangelisia flava Merr.) merupakan salah satu tanaman yang tumbuh di Kalimantan Tengah dan secara turun temurun digunakan sebagai pilihan pengobatan beberapa penyakit kulit dan terbukti mempunyai aktivitas antibakteri. Pembuatan sediaan topikal antibakteri berbahan fraksi aktif A. flava sangat potensial dilakukan untuk mengoptimalkan penggunaan dalam pengobatan sekaligus meningkatkan nilai ekonomis dari A. flava. Tujuan penelitian ini untuk mendapatkan formula gel fraksi aktif A. flava sebagai antibakteri yang paling baik secara fisik.Formula gel dibuat dengan variasi jenis dan konsentrasi gelling agent.Gel fraksi aktif A. flava diuji secara fisika, kimia, dan biologi seperti organoleptis, homogenitas, daya sebar, pH, daya lekat, dan daya hambat terhadap Staphylococcus aureus. Hasil formulasi sediaan gel fraksi aktif A. flava dengan basis NaCMC memenuhi syarat sifat fisik dan zona hambatan 11,6 mm pada Formula 1 dan 13,4 mm pada Formula 2, sedangkan sediaan gel dengan basis Carbophol 943 pada Formula 1 dan 2 memenuhi syarat sifat fisik dan zona hambat 10,9 mm pada Formula 2.Formula gel yang memenuhi kriteria secara fisik adalah Formula 2 dengan Carbophol 1,5% sebagai gelling agent. Kata Kunci: Akar kuning, antibakteri, gel, Staphylococcus aureus ABSTRACT Akar kuning (Arcangelisia flava Merr.) is a plant that grows in Central Kalimantan and has been used as a treatment option for several skin diseases and has been shown to have antibacterial activity. The making of topical antibacterial preparations made from the active fraction of A. flava is very potential to be done to optimize the use in treatment while increasing the economic value of A. flava. The purpose of this study was to obtain the active A. flava fraction gel formula as the best natural antibacterial. The gel formula was made with variations in the type and concentration of the gelling agent. Arcangelisia flava Merr. active fraction gel was tested physical, chemical, and biological, such as organoleptic, homogeneity, spreadability, pH, adhesion, and bacterial inhibitionagainst Staphylococcus aureus. The results of the formulation of the active gel of A. flava based on NaCMC base fulfills physical condition requirements and shows an inhibition zone of 11.6 mmin Formula 1 and 13.4 mm in Formula 2, while gel preparation based on Carbophol 943 Formula 1 and 2 fulfill the physical characteristic requirements and show the inhibition zone of 10.9 mm in Formula 2.Gel formula that meets the physical criteria is Formula 2, with 1.5% Carbophol as a gelling agent. Keywords: Akar kuning, antibacterial, gel, Staphylococcus aureus

Rambusa (Passiflora foetida L) vs. Free Radicals: In Vitro Study with DPPH Method Dewi Sari Mulia; Evi Mulyani; Muhammad Ikhwan Rizki; Mohammad Rizki Fadhil Pratama
Jurnal Pharmascience Vol 6, No 2 (2019): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v6i2.7344

ABSTRAK Rambusa (Passiflora foetida L) adalah tumbuhan obat yang banyak terdapat di berbagai daerah di Indonesia, termasuk di Kalimantan Tengah. Beberapa bagian tumbuhan dari rambusa diketahui memiliki aktivitas antioksidan termasuk di bagian daunnya. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dari daun rambusa yang berasal dari Kalimantan Tengah. Metode yang digunakan adalah metode 2,2-diphenyl-1-picrylhydrazyl (DPPH) yang diukur serapannya dengan Spektrofotometer UV Vis. Hasil yang diperoleh menunjukkan nilai IC50 dari ekstrak etanol daun rambusa senilai 93,269 μg/mL. Meskipun nilai IC50 yang diperoleh lebih rendah dibandingkan senyawa antioksidan standar seperti kuersetin, nilai IC50 dari ekstrak etanol daun rambusa asal Kalimantan Tengah masih lebih tinggi dibandingkan daun rambusa yang diperoleh dari daerah lain Kata Kunci—antioksidan, DPPH, Kalimantan Tengah, Passiflora foetida, rambusa ABSTRACT Rambusa (Passiflora foetida L) is a medicinal plant that is widely found in various regions in Indonesia, including in Central Kalimantan. Some parts of the plant of rambusa are known to have antioxidant activities including in the leaves. This study aims to determine the antioxidant activity of rambusa leaves from Central Kalimantan. The method used was 2,2-diphenyl-1-picrylhydrazyl (DPPH) method which was measured by UV Vis spectrophotometer. The results obtained showed IC50 values of ethanol extract of rambusa leaves worth 93.269 μg/mL. Although the IC50 values obtained were lower than the standard antioxidant compounds such as quercetin, the IC50 value of the ethanol extract of the leaves of rambusa from Central Kalimantan was still higher than that of the rambusa leaves obtained from other regions or some other medicinal plant extracts. Keywords— antioxidants, DPPH, Central Kalimantan, Passiflora foetida, rambusa

PELATIHAN PEMBUATAN SABUN ANTISEPTIK CAIR BERBAHAN DASAR TANAMAN RAMBUSA KALIMANTAN TENGAH Evi Mulyani; Nurul Chusna; Muhammad Priyadi
JMM (Jurnal Masyarakat Mandiri) Vol 6, No 1 (2022): Februari
Publisher : Universitas Muhammadiyah Mataram

Abstrak: Pandemi COVID-19 telah mengubah kebiasan kehidupan di masyarakat termasuk menjaga kebersihan tangan melalui cuci tangan termasuk di lingkungan sekolah. Keterbatasan dalam mendapatkan akses pendidikan dan pelatihan selama pandemi ini melanda menjadikan siswa sekolah memerlukan kegiatan di luar sekolah untuk meningkatkan keterampilan sebagai bekal tambahan. Pengabdian ini bertujuan untuk meningkatkan pengetahuan siswa SMA dalam pembuatan sabun antiseptik cair dengan bahan dasar tanaman rambusa Kalimantan Tengah. Pengabdian dilakukan kepada siswa/i SMA Muhammadiyah 1 Palangka Raya dengan melakukan pelatihan pembuatan sabun antiseptik cair secara daring dan luring terhadap 24 peserta. Evaluasi kegatan dilakukan melalui asessmen awal dan akhir berupa pemberian instrumen kuisioner kepada peserta pelatihan. Hasil menunjukkan telah terjadi peningkatan pengetahuan siswa/i SMA Muhammadiyah 1 Palangka Raya sebesar 30,4%.Abstract: The COVID-19 pandemic has changed the habits of life in the community, including maintaining hand hygiene through hand washing, including in the school environment. Limitations in getting access to education and training during this pandemic have made school students need activities outside of school to improve skills as additional provisions. This service aims to increase the knowledge of high school students in making liquid aniseptic soap with plant-based ingredients typical of Central Kalimantan. The service was carried out to students of SMA Muhammadiyah 1 Palangka Raya by conducting online and offline training on making liquid antiseptic soap for approximately 24 participants. Activity evaluation is carried out through initial and final assessments in the form of giving a questionnaire instrument to the training participants. The results show that there has been an increase in knowledge of students at SMA Muhammadiyah 1 Palangka Raya by 30.4%.

EDUKASI TENTANG VIRUS CORONA DAN PEMBUATAN JAMU EMPON – EMPON UNTUK PENANGANAN VIRUS CORONA DI JUNJUNG BUIH III KOTA PALANGKARAYA Nurul Chusna; Evi Mulyani; Muhammad Priyadi; Ade Irawati; Drenikha Sikhe R; Rismadani Safitri
JMM (Jurnal Masyarakat Mandiri) Vol 5, No 1 (2021): Februari
Publisher : Universitas Muhammadiyah Mataram

Abstrak: Seluruh dunia saat ini tengah dihebohkan dengan Corona Virus Disease (COVID-19) yang tak pernah disangka akan menyebabkan pandemi global dengan jumlah total kasus yang sangat banyak dan terus menyebar ke seluruh dunia termasuk hingga mencapai Kota Palangka Raya, Indonesia. Penyebaran informasi yang keliru saat pandemi dapat membuat masyarakat bingung, resah dan takut sehingga diperlukan upaya edukasi maupun sosialisasi agar masyarakat menjadi paham dan tenang. Pengabdian ini bertujuan untuk melakukan edukasi tentang penanganan virus corona/COVID-19, pembuatan jamu empon-empon agar dapat mengurangi dan mencegah terjadinya risiko penyebaran corona di Junjung Buih III Kota Palangka Raya dengan melibatkan mitra ketua RW dan perkumpulan ibu-ibu. Kegiatan ini dilakukan melalui 3 tahapan yaitu persiapan (observasi), pelaksanaan kegiatan (edukasi dan sosialisasi) dan evaluasi. Hasil dari kegiatan ini adalah kegiatan ini diikuti oleh 32 warga Junjung Buih III yang mampu meningkatkan pemahaman dan kesadaran warga dalam pencegahan virus corona yang terlihat pada penggunaan masker, hand sanitizer, mencuci tangan maupun mengkonsumsi jamu empon-empon yang dibuat langsung di rumah. Abstract: The whole world is currently in shock with the Coronavirus Disease (COVID-19) which was never expected to cause a global pandemic with a very large number of cases and continues to spread throughout the world including reaching Palangka Raya City, Indonesia. The dissemination of misinformation during a pandemic can make people confused, anxious, and afraid so that educational and socialization efforts are needed so that people understand and are calm. This activity aims to provide education about the handling of the coronavirus/COVID-19, making herbal medicine jamu empon-empon in order to reduce and prevent the risk of spreading corona in Junjung Buih III, Palangka Raya City by involving RW chief partners and women's associations. This activity is carried out in 3 stages, namely preparation (observation), implementation of activities (education and socialization), and evaluation. The result of this activity was that this activity was attended by 32 residents of Junjung Buih III who were able to increase people's understanding and awareness of the prevention of the coronavirus which can be seen in the use of masks, hand sanitizers, washing hands, and also consuming jamu empon-empon made directly at home (home made).

Title

Found 18 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 18 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 18 Documents
Search