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All Journal Pharmascience Jurnal Surya Medika PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Bitnet: Jurnal Pendidikan Teknologi Informasi Borneo Journal of Medical Laboratory Technology Journal of Community Development Majalah Cendekia Mengabdi
Fera Sartika
Universitas Muhammadiyah Palangkaraya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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KADAR SERUM GLUTAMATE PIRUVAT TRANSAMINASE (ALT) PADA PENGONSUMSI MINUMAN BERALKOHOL DI KECAMATAN BANAMA PULANG PISAU KALIMANTAN TENGAH Sartika, Fera; Prissilia, Yessy
Jurnal Surya Medika Vol 3, No 1 (2017)
Publisher : Fakultas Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hati berperan penting untuk mendetoksifikasi zat kimia yang tidak berguna ataumerugikan tubuh. Terdapat banyak faktor yang mempengaruhi kerusakan hati, seperti misalnya virus, bakteri, toksisitas dari obat-obatan dan bahan kimia serta konsumsi alkohol yang berlebihan. Konsumsi alkohol dalam jangka waktu yang lama dengan jumlah tertentu dapat menyebabkan berbagai penyakit, salah satunya adalah gangguan fungsi hati seperti penyakit hati alkoholik (alcoholic liver disease). Gangguan mekanisme di hati dapat mengakibatkan terjadinya pembengkakan dengan adanya kenaikan enzim transaminase yang diproduksi oleh hati, yaitu Alanin Aminotransferase (ALT) atau Aspartat aminotransferase (AST), namun pemeriksaan Alanin Aminotransferase (ALT) lebih spesifik dilakukan karena enzim tersebut lebih banyak diproduksi di hati, sehingga enzim ini dapat digunakan untuk menilai kelainan atau gangguan pada fungsi hati. Hasil pemeriksaan kadar ALT serum pengonsumsi minuman beralkohol berkisar antara 12-86 U/I, dimana kadar ALT normal dari 30 sampel sebanyak 28 orang yaitu 93,33% dan kadar ALT lebih dari normal sebanyak 2 orang yaitu 6,67%.
Gambaran Laju Filtrasi Glomerulus Pada Penderita Diabetes Mellitus Tipe 2 Di RSUD Dr. Doris Sylvanus Palangka Raya Fera Sartika; Dwi Purbayanti; Davida Safitri
Jurnal Surya Medika (JSM) Vol 3 No 2 (2018): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (346.292 KB) | DOI: 10.33084/jsm.v3i2.92

Abstract

Diabetes Mellitus (DM) adalah suatu penyakit dimana tingginya kadar glukosa darah yang disebabkan oleh pankreas gagal memproduksi insulin atau terjadinya resistensi insulin. DM digolongkan atas DM tipe 1 dan DM tipe 2. DM tipe 2 yang tidak ditangani dengan baik akan menimbulkan berbagai komplikasi yaitu komplikasi akut dan komplikasi kronis. Komplikasi kronis DM tipe 2 dapat berupa komplikasi mikrovaskular dan makrovaskular. Nefropati diabetik merupakan salah satu komplikasi mikrovaskuler, yaitu komplikasi yang terjadi pada pembuluh darah. Akibat tingginya kadar glukosa dalam darah dapat membuat terganggunya fungsi ginjal. Kemungkinan adanya penurunan fungsi ginjal pada penderita DM dapat diketahui salah satunya dengan penentuan klirens kreatinin. Salah satu indeks fungsi ginjal yang dapat diukur secara tidak langsung dengan perhitungan klirens kreatinin adalah Laju Filtrasi Glomerulus (LFG), dengan menggunakan rumus Formula Corkroft-Gault. Penelitian ini bertujuan untuk mengetahui gambaran laju filtrasi glomerulus pada penderita DM tipe 2 di RSUD dr. Doris Sylvanus Palangka Raya. Penelitian ini menggunakan metode deskriftif untuk menggambarkan laju filtrasi glomerulus pada penderita DM tipe 2. Jumlah sampel yang diperoleh adalah 41 orang. Hasil penelitian berdasarkan rumus Formula Corkroft-Gault menunjukkan LFG normal 10%, Penurunan ringan LFG 15%, Penurunan moderat LFG 70%, Penurunan berat LFG 5%, dan Gagal ginjal 0%.
Kadar Serum Glutamate Piruvat Transaminase (Alt) Pada Pengonsumsi Minuman Beralkohol Di Kecamatan Banama Pulang Pisau Kalimantan Tengah Fera Sartika; Yessy Prissilia
Jurnal Surya Medika (JSM) Vol 3 No 1 (2017): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.362 KB) | DOI: 10.33084/jsm.v3i1.212

Abstract

The liver plays an important role in detoxifying chemicals that are not useful or harmful to the body. There are many factors that affect liver damage, such as viruses, bacteria, toxicity from drugs and chemicals and excessive alcohol consumption. Alcohol consumption over a long period of time with a certain amount can cause various diseases, one of which is liver dysfunction such as alcoholic liver disease. Disruption of the mechanism in the liver can result in swelling with an increase in liver transaminase enzymes produced, namely Alanine Aminotransferase (ALT) or Aspartate aminotransferase (AST), but more specific Alanine Aminotransferase (ALT) tests are carried out because these enzymes are produced in the liver, so that this enzyme can be used to assess abnormalities or disorders of liver function. The results of the examination of serum ALT levels consuming alcoholic beverages ranged from 12-86 U / I, where the normal ALT levels from 30 samples were 28 people, namely 93.33%, and ALT levels were more than normal as much as 2 people, namely 6.67%.
Daya Hambat Air Kelapa (Cocos nucifera) terhadap Pertumbuhan Bakteri Salmonella typhi dan Escherichia coli Fera Sartika
Jurnal Surya Medika (JSM) Vol 4 No 2 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (474.022 KB) | DOI: 10.33084/jsm.v4i2.603

Abstract

Coconut products are known to have anti-bacterial activity. One product of coconut is coconut water. Coconut water has benefits in food processing, especially for health. Coconut water contains tannin or antidote (anti-poison) which is antibacterial which will inhibit bacterial growth. This study aims to determine the antimicrobial effects of coconut water by testing the inhibition of Salmonella typhi and Escherichia coli bacteria. This type of research uses experimental or experimental methods. Before the inhibitory test is carried out, phytochemical tests of coconut water are carried out such as flavonoids, alkaloids, tannins, saponins, and steroids. The results showed that coconut water does not contain the chemical compounds of flavonoids, alkaloids, tannins, saponins, and steroids. The results of the inhibitory test indicate that coconut water cannot inhibit the growth of Salmonella typhi and Escherichia coli bacteria.
Profil Kadar Hemoglobin dan Indeks Eritrosit pada Penjual Ikan Bakar di Kota Palangkaraya Fera Sartika; Dwi Purbayanti; Eny Lestari
Jurnal Surya Medika (JSM) Vol 5 No 1 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (500.805 KB) | DOI: 10.33084/jsm.v5i1.957

Abstract

The process of fish by baking or burning using charcoal can produce toxic chemical compounds, one of which is a carbon monoxide (CO) compound. CO compounds can be inhaled into the lungs through the respiratory system in humans, thereby replacing the position of oxygen to bind to hemoglobin and consequently, the level of oxygen in the blood becomes reduced. The purpose of this study was to determine the profile of hemoglobin and erythrocyte indices of the grilled fish seller selling around Pahandut District, Palangka Raya City. The study was conducted with a purposive sampling technique and the number of samples in this study was 25 people. The results showed normal hemoglobin levels of 24 people and below the normal value of 1 person. Normal MCV values were 16 people, MCV below normal values were 9 people (36%). Normal MCH 21 people (84%), MCH under normal values 2 people (8%), normal MCHC 19 people (68%), MCHC below normal values 1 person (1%), MCHC more than normal values 5 people (20%). Profile and erythrocyte indices of 25 samples obtained normal hemoglobin levels of 24 people (96%) and hemoglobin levels below normal values of 1 person (4%). The results of 1 person (4%) cytitrocyte index were suspected of having microcytic hypochromic anemia which could be caused by iron deficiency, and 1 person (4%) of the type was suspected of having microcytichipchromic anemia.
Seroprevalensi Hepatitis B pada Pemulung Sampah di Kota Palangka Raya Suratno Suratno; Fera Sartika
Jurnal Surya Medika (JSM) Vol 5 No 2 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (284.485 KB) | DOI: 10.33084/jsm.v5i2.1297

Abstract

Hepatitis B is a hepatitis B virus (HBV) infection which can exacerbate the liver and cause acute and chronic disease. The most susceptible group to hepatitis B transmission is waste pickers. This study aimed to determine: (1) the level of Hepatitis B virus infection among waste pickers in several temporary waste shelters in Palangka Raya, and (2) risk factors for hepatitis B virus infection in waste pickers in several temporary waste shelters in Palangka Raya. The observational analytic study using a cross-sectional study design was used in this research. The purposive sampling technique was carried out to involve 32 waste pickers in Palangka Raya. Examination of hepatitis B screening through HBsAg test to waste scavenger blood samples using the Rapid Test method. The results showed that the rate of hepatitis B infection based on positive HBsAg examination was 3.1% of respondents. Risk factors for transmission or exposure to hepatitis B that are directly related to the activity of garbage scavengers are not using protective equipment (PPE) gloves and bare hands waste collection, respectively 3.6% and 6.7%
Potensi Ekstrak Akar Kalakai (Stenochlaena palutris Bedd) Sebagai Antihiperlipidemia Yang Diuji Secara In Vivo Rabiatul Adawiyah; Fera Sartika; Fahruddin Arfianto
Jurnal Pharmascience Vol 7, No 1 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i1.8075

Abstract

ABSTRAK Tumbuhan kalakai atau sering disebut paku haruan atau pakis  merupakan tumbuhan khas Kalimanatan yang banyak digunakan sebagai tumbuhan obat. Kalakai mengandung beberapa senyawa bioaktif seperti fenolik, flavonoid, alkaloid dan keluarga terpenoid yang efektif sebagai antioksidan.  Tujuan penelitian ini untuk menentukan aktivitas antihiperlipidemia dar i ekstrak akar kalakai yang diuji secara in vivo pada tikus wistar. Metode yang digunakan adalah melakukan uji aktivitas antihiperlipidemia dengan cara memberi perlakuan hewan coba dan melakukan pengukuran kadar trigliserida dan kolesterol total dengan menggunakan Spektrofotometer UV-VIS. Hasil penelitian diketahui bahwa peningkatan dosis dapat meningkatkan aktivitas dari ekstrak akar  kalakai. Semakin meningkatnya dosis,  maka terjadi peningkatan pertemuan antara flavonoid dengan reseptor di permukaan sel, sehingga terjadi peningkatan aktivitas. Aktivitas dari pemberian dosis ke-3 dari kadar trigliserida sebesar 49,8 mg/dl sedangkan untuk kadar kolesterolnya sebesar 41,8 mg/dl pada hasil yang didapat dari ekstrak akar kalakai  mendekati pemberian dari kadar  simvastatin. Berdasarkan hal tersebut, maka ekstrak dengan dosis 400 mg/KgBB memiliki potensi untuk teliti lebih lanjut dan dapat digunakansebagai obat alternatif pada pengobatan hiperlipidemia. Keadaan hiperlipidemia tidak hanya terkait kolesterol, tetapi mencakup kadar trigliserida di dalam darah. Kemampuan suatu obat dalam menurunkan kadar kolesterol sekaligus kadar trigliserida, akan memberikan keuntungan terhadap pengobatan pasien hiperlipidemia. Penggunaan akar kalakai tidak hanya terbatas pada pengobatan karena bahan alam dapat digunakan sebagai pencegah timbulnya penyakit terutama hiperlipidemia yang terjadi pada pasien degeneratif. Kata kunci : Ektrak akar kalakai, In Vivo, Kolesterol, SpektrofotometerUV-VIS, Trigliserida  ABSTRACT Kalakai plants or often called haruan nails or ferns are typical Kalimanatan plants which are widely used as medicinal plants. Kalakai contains several bioactive compounds such as phenolic, flavonoid, alkaloid and terpenoid family which are effective as antioxidants. The purpose of this study was to determine the antihyperlipidemic activity of kalakai root extract which was tested in vivo in Wistar rats. The method used is to test the activity of antihyperlipidemia by giving treatment of experimental animal and to measure levels of triglycerides and total cholesterol using a UV-VIS spectrophotometer. the results of the study note that increasing the dose can increase the activity of the kalakai root extract. As the dose incr eases, there is an increase in the linkage between the flavonoids and receptors on the cell surface, resulting in increased activity . The activity of administering the 3rd dose of triglyceride levels was 49.8 mg/dl whereas for cholesterol levels it was 41.8 mg/dl in the result obtained from the extract of kalakai root approaching the administration of simvastatin levels. Based on this, the extract at a dose of 400mg/kg has the potensial for further scrutiny and can be used as an alternative drug in the treatment of hyperlipidemia. The state of hyperlipidemia is not only related to cholesterol, but includes the level of triglycerides in the blood. The ability of a drug to reduce cholesterol levels as well as triglyceride levels, will provide benefits to the treatm ent of hyperlipidemia patients. The use of kalakai root is not only limited to treatment because natural ingredients can be use d as a prevention of disease, especially hyperlipidemia that occurs in degenerative patients. Keywords: Kalakai root extract, In Vivo, Cholesterol, Triglyceride, UV-VIS Spectrophotometer
Kadar HbA1c pada Pasien Wanita Penderita Diabetes Mellitus Tipe 2 di Rsud Dr. Doris Sylvanus Palangka Raya Fera Sartika; Nurul Hestiani
Borneo Journal of Medical Laboratory Technology Vol 2 No 1 (2019): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.445 KB) | DOI: 10.33084/bjmlt.v2i1.1086

Abstract

Laboratory tests recommended by the ADA as a supportive examination for diagnosing DM are Hemoglobin Adult 1C (HbA1c), HbA1c examination can be used as a reference for monitoring diabetes mellitus because HbA1c can provide clearer information about the true condition in people with diabetes mellitus. HbA1c examination is an examination that reflects the average blood glucose level over a period of 2-3 months. The purpose of this study was to determine the description of HbA1c in female patients suffering from type 2 diabetes mellitus in RSUD dr. Sylvanus Palangka Raya. This research was conducted using a cross sectional study method with accidental sampling technique. The sample used in this study was patients suffering from type 2 diabetes mellitus in RSUD dr. Doris Sylvanus Palangka Raya taken by 15 people. Then examined using the boronate affinity method. The results obtained by the HbA1c category were 4 people (26.67%) good, 6 people (40%) medium and 5 people (33.33%) bad.
APTT (Activated Partial Thromboplastin Time) dan (Prothrombin Time) pada Penderita Diabetes Melitus Tipe 2 di RSUD dr. Doris Sylvanus Palangkaraya Rinny Ardina; Fera Sartika; Lidya Prihatini Nainggolan
Borneo Journal of Medical Laboratory Technology Vol 2 No 2 (2020): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (196.941 KB) | DOI: 10.33084/bjmlt.v2i2.1384

Abstract

Patients with type 2 diabetes mellitus (T2DM) have a high risk of atherothrombotic events. Hyperglycemia and other metabolic disorders in T2DM are associated with abnormalities of hemostasis system and thrombosis that contribute to cardiovascular disease. Routine laboratory tests to examine the hemostasis system are Activated Partial Thromboplastin Time (APTT) and Prothrombin Time (PT). This study aimed to describe the abnormalities of APTT and PT in patients with T2DM in RSUD dr. Doris Sylvanus Palangkaraya. Twenty subjects with T2DM in RSUD dr. Doris Sylvanus Palangkaraya were obtained using purposive sampling techniques and blood samples were examined with a COATX Biosystem coagulation using photocolorimetric method. This study found that was 70% APTT are shortened, 5% APTT are prolonged and 25% APTT were normal. While the PT results were 25% PT are shortened and 75% APTT were normal. Abnormalities of APTT and PT in T2DM patients in RSUD dr. Doris Sylvanus Palangkaraya showed an abnormality of the coagulation system so as to allow a tendency for bleeding and cardiovascular disease in T2DM patients. Routine coagulation test should be continued to help better diabetes mellitus management in order to prevent micro or macrovascular complications.
Gambaran Stigma Masyarakat tentang Covid-19 di Kepanjen Malang Yuyud Wahyudi; Lilis Sulistiya Nengrum; Fera Sartika
Borneo Journal of Medical Laboratory Technology Vol 4 No 1 (2021): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v4i1.2955

Abstract

Stigma is a sign that is created on the human body to be shown and to inform the public that a person who has that sign constitutes no morals and primness expression that belongs to someone. The purpose of this study is to understand society's stigma about Covid 19 in Cepokomulyo Village, Kepanjen sub-district Malang regency. The research design used in this research is a descriptive method and cross-sectional approach. The sampling technique in this research uses Cluster Sampling of as many as 364 respondents. The respondents were given a questionnaire by the researcher, it is a questionnaire variable of society stigma (sign, signal, stereotypes, prejudice, and discrimination) to validate the data. In validating the questionnaire, the researcher used I-CVI (content validity index). And the data is stated valid with a score of 0.935. Reliability test from all the questionnaires which had been fulfilled by the respondents gave the results, those are signal/cues 0.829, Stereotypes 0.805, prejudice 0.850, and discrimination 0.802. As the result of the research, there are 4 variables that mean good categories. The percentage highest scores lie in stereotypes variable as many as 94.2% (n=364), which means the society stigma is good. Because society does not judge people by appearance. The conclusion, society did not give a bad stigma about Covid 19. Good communication and getting information can be solutions to build up society's stigma about covid 19. And the bad stigma would not show up in society.
Co-Authors Agus Agus Chandra Anugrah Putra Davida Safitri Dwi Purbayanti Eny Lestari Evi Mulyani Fahruddin Arfianto Fitria Hariati Ramdhani Hanida , Luthfiani Hidayani, Al Lidya Prihatini Nainggolan Maulida, Riska Nanda, Putri Nengrum, Lilis Sulistiya Nova Nova Nurhalina Nurul Hestiani Nurul Qamariah, Nurul Panji Ratih Suci, Panji Ratih Rabiatul Adawiyah Ramadhani, Fitria Hariati Ramdhani , Fitria Hariati Rezqi Handayani Rinny Ardina Risqika Yulia Tantri Paramawidhita Suratno Suratno Wahfiudin, M. Noval Windya Nazmatur Rahmah Yessy Prissilia Yessy Prissilia, Yessy Yuda Ednisa Sri Maduren Yuyud Wahyudi, Yuyud