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Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Pembangunan Nasional Veteran Jakarta
ISSN : 02163438     EISSN : 26211122     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 244 Documents
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Retroperitoneal Abcess Profiles in a Tertiary Hospital in Bandung, Indonesia : Long Term Retrospective Study Daniel Saputra; Ricky Ardiansjah
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16, No 1 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i1.3414

Abstract

Retroperitoneal abscess is a rare and difficult-to-diagnose condition. The delay in diagnosis is the primary cause of mortality. We did a case series investigation to describe the profiles of retroperitoneal abscesses.  We obtained retrospective data from medical records. We reviewed thirty patients admitted to our hospital with retroperitoneal abscesses from January 2013 to December 2019. Of 30 patients reviewed, 56.67% were male, with 50.14 years-old mean age. Approximately 46.67% presented with a chief complaint of back pain, and about 63.33% of cases had a fever. The most prevalent source was genitourinary, which accounted for 60% of the cases. The most common type of abscess was the perirenal abscess. Diabetes mellitus, malignancy, and an immunocompromised condition were all prevalent comorbidities. Escherichia coli was the most prevalent pathogen (46.66%), followed by Klebsiella pneumoniae (26.67%). For genitourinary abscesses, percutaneous drainage was typically used, whereas surgical drainage was recommended for gastrointestinal abscesses. The mortality rate of those conditions was 13.33%. Retroperitoneal abscesses have a wide range of clinical manifestations and causes. The treatment for retroperitoneal abscesses differed depending on the etiology and severity of the infection. 
Determinant Factors of Low Cognitive, Motoric and Language Performance of HIV-Infected Children Putu Indah Budiapsari; I Nyoman Supadma
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16, No 1 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i1.4132

Abstract

The Effects of HIV infection on children’s physical growth, psychological health, and neurodevelopment are essential. We aimed to find out the determinants factor of low cognitive, motoric and language performance of HIV-infected children. This study examined 68 HIV-infected children ranged 0-36 months. Cognitive, motoric and language were assessed using Cognitive Adaptive Test (CAT) and Clinical Linguistic and Auditory Milestone Scale (CLAMS) score which are components of of Capute Scale. Data was analyzed using cross tab, and significant Pearson chi-square (p < 0.05) was used to identify the determinant factors. The result showed that CD4 level, length of antiretroviral treatment, age, stage of HIV infection, socio economic status, and family income were determinant factors of low cognitive, motoric and language performance of HIV infected children. It can be concluded that cognitive, motoric and language were affected by CD4 level, length of antiretroviral treatment, age, stage of HIV infection, socio economic status, and family income. 
Retrospective Analysis of COVID-19 Vaccination in a University Hospital and the Relationship with the Epidemic Rate Işıl Deniz Alıravcı; Fatma Gümüşer; Alper Şener
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16 No 2 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i2.4818

Abstract

It was aimed to make a retrospective analysis of the vaccines administered in the vaccine unit of our hospital since the beginning of the COVID-19 pandemic. The study was carried out retrospectively from the vaccination records our hospital, 14 January 2021 to 01 July 2022. In the 18-month period, a total of 75079 (100%) vaccines were administered, 59386 (79%) were Biontech and 15693 (21%) were Sinovac vaccines. Only Sinovac was available until June, therefore, 66% of the Sinovac vaccines were administered in the first five months period. After the Biontech vaccine started to be applied in our hospital, the rates of Sinovac vaccination have declined drastically.  When the epidemic and vaccination graphs were examined separately, inverse correlation was found between the peak points of the epidemic and vaccine graphics. Biontech was found to be the most preferred vaccine by individuals against COVID-19 in this study.
Critically Ill Patient with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Developing Sepsis and Potassium Disorder: a Case Report in Secondary Hospital Setting Regia Anadhia Pinastika; Indah Rahmawati; Tiara Nadya Putrianda
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16 No 2 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i2.5071

Abstract

Sepsis and electrolyte disturbances are frequently experienced among acute exacerbation of chronic obstructive pulmonary disease (AECOPD) patients. It is characterized by organ failure brought on by unbalanced host response to infection. A 63-year-old male presented to the hospital with the complaint of breathlessness with the oxygen saturation of 76%. The leukocyte level increased to 19.000 and the Potassium level decreased to 2.88. The combination of antibiotics, Potassium supplement, oxygen support through NRM of 15 liters per minute and symptomatic treatment were administered to the patient. The NRM was then changed to HFNC due to his worsening condition and successfully decreased oxygen demand. The patient’s condition has made a significant improvement after seven days of hospitalization. Patients with AECOPD are at higher risk of developing sepsis and electrolyte disturbances. Sepsis will change the biological system of the body due to different pathophysiology such as electrolyte imbalance and obviously engaged with the pathogenesis of ensuing regular intensifications. It is important for the clinicians to know the effective management for the patient, so that the critical phase can be passed even at the limited facilities. 
Isolation and Characterization of Adipose-Derived Mesenchymal Stem Cell Exosomes: an In-Vitro Study Jessica Fiolin; Ismail Hadisoebroto Dilogo; Radiana Dhewayani Antarianto; Ludwig Andre Pontoh
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16 No 2 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i2.4867

Abstract

Exosomes from Mesenchymal Stem Cells (MSC) is currently one of the highlighted research due to its more specific action on the target tissue. Exosome is one of the MSC Extracellular Vesicle (EVs) that acts as a mediator in the cellular communication. However, not so many literatures have succeed in elaborating its isolation and characterization process. This study aimed to explain the method used in exosomes isolation from Adipose-Derived MSC (ASC) and elaborate its characteristics. This is an in-vitro study performed in the Stem Cell and Tissue Engineering (SCTE) Indonesia Medical Education and Research Institute (IMERI) laboratory. Ultracentrifugation method was performed to isolate exosome from ASC. The exosome were characterized based on its particle size, morphology, and CD63 and CD81 expression for its purity. We were able to isolate sterile exosome from ASC by performing differential ultracentrifugation. The mean size of exosome was 88.7 nm ± 40 nm SD and showed expression of CD63 and CD81. Exosome was successfully isolated from ASC using ultracentrifugation method and characterization following the MISEV standard should be implemented in order to meet the therapeutic efficacy and safety issues as a regenerative agent.
Capacity to Consent of People with Dementia: a Narrative Review from an Ethical Perspective Urfa Khairatun Hisan; Nurul Qomariyah; Kristina Elizabeth
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16 No 2 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i2.4744

Abstract

People with dementia have impairment to execute daily life activities by presenting as a deterioration of mental processes, such as memory, thinking, reasoning, and judgment. Many participants in dementia research may lack the capacity to provide informed consent. Additional safeguards are needed for dementia research participants’ protection because of their vulnerability. Only after carefully weighing the risks and possible benefits for the participants in the research may it be decided to use vulnerable participants. The intention to prevent harm pushes against the removal of autonomy. This dilemma is the driving force behind this article's narrative review of the capacity to consent problems in dementia research. For this critical narrative review, we conducted a thorough search of Scopus, PubMed, and Wiley Open Library for literature addressing the ethical and legal issues on the capacity to consent of people with dementia. We outline the dilemmas and difficulties that surround them including the related ethical principles, the informed consent process, capacity to consent, and safeguards for the participant in research involving people with dementia.
The Effect of High-Intensity Interval Training on Blood Lactate Levels and Rate of Perceived Exertion in Sedentary Healthy Adults Nur Ahlina Damayanti; Nury Nusdwinuringtyas; Tresia Fransiska Uliana Tambunan; Aria Kekalih
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16 No 2 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i2.5104

Abstract

The high-intensity interval training has been seen to be beneficial for various populations. This study aimed to determine the effect of high-intensity interval training (HIIT) on blood lactate levels and rate of perceived exertion (RPE) in sedentary healthy adults. A pre-post study was conducted on adults that were stated healthy and sedentary on physical activity. All participants were given HIIT with a total duration of 20 minutes for 12 sessions using a treadmill. Blood lactate level and RPE was recorded on the 1st and 12th session. A significant decrease in blood lactate level and RPE after giving HIIT was found with a reduction of 1,1 mmol/ L and 2 on the Borg Scale respectively (p<0.0001). Further research is needed using field-based exercise testing to determine exercise prescription and to obtain the benefit of HIIT in populations with cardiovascular risk factors before utilizing it in patients.
Toxigenic Diphtheriae Profile in Children in 2017-2018 Siti Maemun; Aninda Dinar Widiantari; Nur Aliza; Masdalina Pane; Tri Yuli Setianingsih; Yeni Afrina; Farida Murtiani
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16 No 2 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i2.4865

Abstract

Corynebacterium diphteriae is divided based on its ability to produce toxin. Toxigenic C. diphteriae is the type that has capacity to produce toxin and life threatening. This study was descriptive study in Corynebacterium diphteriae found in children less than 18 years old who were administered to National Infection Center Prof. Dr. Sulianti Saroso. We found 36 viable toxigenic C. diphteriae isolates, which 52.8% intermedius strain, 33.3% gravis strain, 8.3% mitis, and 5.6% non-strain. Most of the host (52,8%) were 60-144 months years old. Majority of the host had completed basic vaccination recommended by Indonesian Paediatrician Association while 75% of them hadn’t gotten the supplementary doses. Fever (48.5%) and odynophagia (54.5%) were experienced by toxigenic intermedius strain infection.  Snoring (50%) and thick pseudomembran mostly found in gravis strain host while Bullneck sign found in intermedius strain infection. Complications like airway obstruction, chronic kidney disease, and myocarditis were found in host with toxigenic intermedius strain by 66.7%, 100%, and 75%. Death case were also mostly with this strain. Intermedius strain were mostly found in this study. Complications and mortality were also connected to intermedius strain infection.
Comparison in Levels of Interleukin 6, Ferritine and Neutrophil-Lymphocyte Ratio in COVID-19 Patiens Treated in ICU and Non-ICU Nanda Oktavia; Efrida Efrida; Zelly Dia Rofinda
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16 No 2 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i2.4891

Abstract

Inflammation is caused by infectious diseases, including COVID-19. Severe inflammatory responses contribute to weak adaptive immune response, there by resulting in immune response imbalance. Circulating biomarkers can represent inflammation and immune status are potential predictors for the prognosis of COVID-19 patients. Ferritin and interleukin-6 can serve as significant biomarkers in the detection of cytokine storm, systemic inflammation, and the prognosis of COVID-19. Neutrophil-lymphocyte ratio is an independent prognostic biomarker for COVID-19 patients. The aim of this study to determine differences levels of IL-6, ferritin, and NLR in COVID-19 patients treated ICU and non-ICU. This study was comparative cross-sectional design of 62 COVID-19 patients. Research was conducted at the Central Laboratory and Medical Record of Dr. M. Djamil Padang hospital (May-September 2021). Interleukin-6 levels determined the ECLIA methods, ferritin with the ELFA methods, and NLR with calculation methods. Bivariate data were analyzed with Mann-Whitney test. The characteristics of COVID-19 patients treated in ICU: 64.5% male, average age was 53.52(10.71) years, 48.4% death, and non ICU: female 71.0%, average 42.32 (12.22) years, and recovered 100%. The most common comorbid is hypertension. There were significant differences levels of IL-6, ferritin, and NLR in ICU and non-ICU patients with COVID-19 (p<0.001).
Analysis of Urinary Endothelin-I Levels in Obese Late Adolescents Dian Fahmi Utami; Irfan Idris; Arsyadi Arsyad; Ika Yustisia; A. Aryandi; Husni Cangara
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16 No 2 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i2.5192

Abstract

Obesity is a health problem that often occurs in late adolescents and early adults. Endothelial damage that occurs in obese people can cause increased production of endothelin-1. This study compares urinary endothelin-1 levels in the obese and normal groups. It used analytical research methods with a quantitative approach to collect and measure data in numbers. The study design was cross-sectional by comparing endothelin-1 levels in normal and obese adolescent groups. This research was conducted in Makassar City from April to June 2022. The study population was obese and non-obese people in their late teens and early adulthood. The sample collection technique used in this study is a purposive sampling technique, which is a non-random sampling technique. The number of samples in the study for the Obese group was 26, while in the Normal group was 26. The analysis used the Independent Sample T Test statistical test. The results showed that the average urinary endothelin I level in the obese group was 40,930 ng/l, and in the normal group, 55,547 ng/l. Which shows a significant difference in average endothelin I levels (p<0.05) between the obese and normal groups.

Page 17 of 25 | Total Record : 244

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