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Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Published by Universitas Muhammadiyah Surabaya
ISSN : 25412272     EISSN : 25489526     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 301 Documents
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Evaluating the effectiveness of Thiel embalming solution for preserving cadavers in anatomy and surgical education I Made Rayo Putra Indrawan; Ria Margiana
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.21946

Abstract

Cadavers have played a crucial role in anatomy teaching, owing to their resemblance to the anatomical structures found in living individuals. To optimize the utilization of cadavers, embalming procedures that involve the application of chemical fixative agents are needed. The "soft embalming" approach, which involves various salts as fixating agents, was first developed by Walter Thiel. Although the Thiel solution has demonstrated efficacy in enhancing tissue elasticity, consistency, and color, a study is needed to find the most suitable for embalming with this solution to maximize its utility in the context of anatomy and surgical education. The study results show that the Thiel solution produces the best outcomes for its flexibility, uniformity, and color, which is optimal for anatomical and surgical teaching. The efficacy of Thiel's solution for preserving cadavers for educational intentions is noteworthy for the study of anatomy and surgical procedures. The advantageous characteristics of Thiel embalming include flexibility, consistency, and natural coloring. Nevertheless, it is crucial to consider the restrictions associated with preserving the brain, spinal cord, eye, and musculoskeletal tissues. In conclusion, the utilization of Thiel solution has proven to be an efficient embalming agent for preserving cadavers in the fields of anatomy and surgery education, besides brain, spinal cord, eye, and musculoskeletal systems, should be reconsidered.
Larvicide activity of ethanol extracts from Zodia (Evodia suaveolens S.) leaves and Cananga (Cananga odorata) flowers on Aedes aegypti larvae Purista Tiara Dewi; Listiana Masyita Dewi
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22132

Abstract

Controlling Aedes aegypti population in Dengue management programs is often carried out using high doses of synthetic insecticides, such as temephos, that may lead to resistances. An alternative of natural ingredient such as Zodia (Evodia suaveolens S.) leaves, that containing evodiamine and Cananga (Cananga odorata) flower that containing linalool, appears to be a promising larvicide. This study aims to determine the effectivity of ethanol extracts from Zodia leaves and Cananga flowers on the mortality of Aedes aegypti larvae. This experimental study using Aedes aegypti larvae at stage of III-IV. Each ingredient was extracted by the maceration method and then prepared at concentration of 2.5% and 5%. PEG 400 was also added as a diluent. Observations performed every 6 hours, for 24 hours. Data analysis using Kruskal Wallis test and Dunn's test. Within 24 hours, in each of study group, there was 100% larval mortality. The Kruskal Wallis test resulting p-value of <0.05. From Dunn’s test, comparisons between each study group and the negative and positive control groups yielded p-values <0.05 and 1.000, respectively. Thus, it can be said that ethanol extracts from Zodia leaves and Cananga flowers are as effective as temephos as larvicide on Aedes aegypti larvae
Mesial Temporal Lobe Epilepsy as a Common but Elusive Case: A Case Report Darren Junior; Putu Kintan Wulandari; Saktivi Harkitasari; I Wayan Sumardika; Komang Trisna Sumadewi
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22259

Abstract

Epilepsy is a common neuronal disorder that could include partial or generalized seizures due to abnormal brain electrical activity. A 32-year-old female patient was presented to the emergency room with a chief complaint of seizure. The seizure semiology started with epigastric pain, which then progressed into sudden speech arrest. Afterward, the patient experienced left-sided head movement followed by jerkings on the left hand. The patient then became unconscious and experienced full body rigidity. Physical examinations, vital signs, and laboratory results showed no abnormalities. Diagnostic assessments only showed unspecific signs of diffuse cerebral edema through a CT Scan and an atrophy of the right hippocampus with a slight increase in FLAIR signal intensity and dilatation of the right lateral ventricle pericornu through MRI. The patient was given phenytoin and folic acid twice daily. The presence of right mesial temporal sclerosis served as a possible cause of epilepsy in this patient despite having several obscurities. The patient showed atypical signs of generalized tonic seizure progression, adult-onset seizures, and increased MRI FLAIR signal intensity. More detailed examinations and constant reports of epilepsy cases are highly needed among physicians to provide more specific methods and tools to diagnose, classify, and treat epilepsy in the future.
Emergency Pregnancy with Severe Preeclampsia and Total Atrioventricular Block In A 28-Year-Old Woman Muhamad Nofa Cholili; Yahya Irwanto
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22296

Abstract

The co-occurrence of preeclampsia with bradycardia due to total atrioventricular block (TAVB) during pregnancy is a rare yet severe phenomenon. There is limited literature available on this specific combination. This case report aims to contribute valuable insights by documenting the clinical presentation and management of a 28-year-old woman who is diagnosed with severe preeclampsia and total atrioventricular block during pregnancy.   A 28-year-old pregnant woman was referred to the emergency room with dyspnea and vaginal discharge. She had a history of cardiac issues, including atrial septal defect and total atrioventricular block. Her blood pressure was 206/129 mmHg, and a pulse rate of 67 beats per minute. Then, she was diagnosed with severe preeclampsia, hypertensive emergency, and impending eclampsia with a suspect congenital disease contributing to her atrioventricular block. The patient underwent urgent cesarean section intrauterine stabilization and received postoperative care. Postoperatively, the patient reported no further dyspnea or bradycardia. The history of salbutamol usage and the activation of plasminogen activator inhibitor-1 (PAI-1) in patients with atrial septal defects (ASD) is suspected as a potential etiological factor in the pathophysiology of preeclampsia during pregnancy. TAVB can be induced by congenital ASD. In conclusion, the use of salbutamol and activation of PAI-1 in patients with TAVB induced by ASD are suspected as potential causes of preeclampsia during pregnancy.
Sebuah Laporan Kasus Seorang gadis berusia 13 tahun dengan Defek Septum Atrio-Ventrikular Lengkap (subtipe Intermediate) dan Blok AV Total I Ketut Alit Utamayasa; Prima Hari Nastiti; Taufiq Hidayat; Mahrus Abdur Rahman
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22680

Abstract

Atrioventricular septal defects (AVSD) constitute a spectrum of anomalies caused by abnormal endocardial cushion defects. Many classifications have been used to describe AVSD. There is generally subclassified into complete and partial forms. Complete AVSD is characterized by a primum atrial septal defect (ASD) contiguous with an inlet ventricular septal defect (VSD) and a common AV valve. Intermediate AVSD is a subtype of complete AVSD that has distinct right and left atrioventricular valve orifices by a bridging tongue despite having only one common annulus. In some children or adults, we may see unoperated partial or intermediate AVSD, which may be asymptomatic or may present with congestive heart failure, exertional limitation, pulmonary hypertension, infective endocarditis, or heart rhythm disorder. In some cases of AVSD has atrioventricular (AV) conduction disorder, mostly on first-degree AV block. We report a case of a 13-year-old girl with complete AVSD (intermediate subtype) and pulmonary hypertension who is concomitant with total AV block. The patient has undergone implantation of a permanent pacemaker for total AV block and conservative therapy for complete AVSD. Anatomical assessment by trans-thoracal echocardiography (TTE) was essential for diagnostic and detailed morphological characterization of AVSD.
Management of Habitual Patellar Dislocation in Pediatrics Panji - Sananta; Ade Churie Tanjaya; Eka Noviya Fuzianingsih
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22714

Abstract

Habitual patellar dislocation occurs when the knee is bent and returns to its usual position when straightened. Habitual patella dislocation is 13.5 per 100,000 in children under 13 and 147.7 per 100,000 in children 14–18. This review aims to present a comprehensive and complete literature on the management of habitual dislocation of the patella so that appropriate therapy can be obtained. A complete literature review was used in this investigation. Source search databases are PubMed, Science Direct, and Google Scholar. The literature study shows that habitual patellar dislocation in children is infrequent. Stability requires bone and connective tissue that match the patellofemoral joint. Patella alta, torsional, angular, trochlear dysplasia, muscular anomalies, ligamentous laxity, or ligament damage can produce lateral patellar habitual instability. The quadriceps muscle drags laterally to the limb's mechanical axis. Clinical children with recurrent patellar dislocation may experience a sudden dislocation that "disappeared somewhere." If this condition returns, patients frequently develop unusual knee edema and inflammation. MRI, CT, and plain radiography can diagnose this condition. A CT scan can detect trochlear dysplasia. Joint effusion, osteochondral lesions, medial retinaculum tears, and medial patella and lateral femoral condyle cartilaginous discolorations can be seen by MRI. Conservative or surgical treatment of habitual patellar dislocation depends on the deformity and its effects.
Neutrophil-Lymphocyte Ratio, Platelet Lymphocyte Ratio, And Carcinoembryonic Antigen Relationship With Survival In Non-Small Cell Lung Cancer Patients Haryati Haryati; Ayudiah Puspita Mayasari; Farida Heriyani
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22773

Abstract

Inflammation is crucial to cancer development. A complete blood count is standard patient testing. Thus, inflammatory biomarkers like neutrophil-lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) may predict lung cancer prognosis. Serum carcinoembryonic antigen (CEA) is the main predictive marker of most studies. Elevated NLR, PLR, and CEA levels are frequently associated with poorer overall survival in NSCLC patients. A retrospective cross-sectional study included 50 NSCLC medical records patients from Ulin Regional South Kalimantan Hospital. NLR, PLR, and CEA baseline peripheral blood individuals were investigated for NSCLC overall survival (OS). Patients are separated by OS mean into two groups. Mann-Whitney compared variables. The ROC curve and AUC were used to evaluate the above indicators' prognostic value. The mean of OS was 6 months. NLR, PLR, and CEA patients in ≤ 6 months had higher median values compared to > 6 months groups (8.73 vs. 4.3; 301.23 vs. 217.81; and 106 vs. 27.87). Survival was significantly associated with NLR and CEA (p-values 0.010 and 0.011). NLR >5.90 with AUC 0.725 (sensitivity 63.6%, specificity 29.4%) and CEA >41.39 ng/mL with AUC 0.722 (sensitivity 72.7%, specificity 29.4%). Parallel tests of NLR and CEA testing increased sensitivity and specificity (75.8%, 70.6%). This study revealed that elevated NLR and CEA are associated with patient survival, and monitoring both markers enhances survival prediction accuracy. It can improve insight into disease progression and adjust the therapeutic approach for NSCLC patients.
Implant Failure and Acetabular Protrusion Post Austin Moore Prosthesis: A Case Report Bagus Meurah Suropati; Bagus Wibowo Soetojo; Rakha Rahmatullah Ibrahim; Totot Mudjiono
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22978

Abstract

Implant failure and acetabular protrusion are significant complications following Austin Moore prosthesis insertion, particularly in elderly patients with hip fractures. Total hip arthroplasty (THA) offers superior outcomes compared to hemiarthroplasty (HA) but comes with its own set of challenges. Understanding the risk factors and implications of these complications is crucial for choosing effective management.  In this article, we report a 76-year-old woman who presented with severe left hip pain post-fall, eight years after HA with an Austin Moore prosthesis due to a trochanter fracture. The patient was able to walk with a walker before the fall. Physical examination revealed tenderness and limited range of motion. Radiographic imaging confirmed acetabular protrusion and AMP neck fracture. Conversion to THA using a hybrid system was performed successfully, with the patient exhibiting no post-operative complications. This case report showed that implant failure and acetabular protrusion pose complex challenges, exacerbated by patient demographics, implant design, and bone quality. THA emerges as a preferred option due to its superior outcomes, although conversion from HA is associated with increased risks. Early diagnosis and intervention, as well as a multidisciplinary approach and careful consideration of patient-specific factors, are crucial for optimizing patient outcomes and quality of life.
Impact of Obesity With Chronic Hypertension In Pregnancy Age 35 Years Nila Triayuningsasi; Halimatus Sa’diyah; Hera Yulianingsih
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.23213

Abstract

The incidence of pregnancy with obesity in Indonesia reaches 21.8%. This can be more serious, if the pregnant woman is too old (≥ 35 years) then there will be more complications for the mother and fetus. This case study was written based on midwifery management, in the form of subjective, objective documentation, analysis, and management. Based on a case study conducted on GIP0A0 ​​gestational age 36 weeks, 35 years old with obesity and old age. The impact of obesity found is chronic hypertension which will reduce the supply of oxygen and food from the mother to the baby so that the fetus is diagnosed with suspected Intrauterine Growth Restriction (IUGR). The mother is categorized as level II obese, obesity increases the risk of narrowing of the blood vessels by the accumulation of fat, which causes poor blood circulation which transports O2 and nutrients to the baby so that the fetus's weight does not match the gestational age, what is detected from TFU does not match the gestational age, in fact, accompanied by minimal amniotic conditions (oligohydramnios). To prevent complications for the mother and baby, delivery is carried out by cesarean section (SC). The mother's baby was a High Social Value Baby (HSVB), and after SC there was no success in providing exclusive breastfeeding, due to the mother's lack of knowledge about how and the benefits of breastfeeding.  The mother chose IUD contraception which was inserted at the time of delivery. In conclusion, appropriate care provided by midwives during pregnancy, childbirth, newborns, postpartum and family planning is very important for the health of mothers and babies. So that early detection of risk factors can be minimized and possible complications can be prevented.
The Relationship Between HbA1c Levels and Severity of COVID-19 Patients with Diabetes Mellitus at Haji General Hospital, East Java Province Nabil Salim Ambar; Muhimmatul Aaliyah Rahmadina; Mohammad Subkhan; Audy Meutia Ariana
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.23444

Abstract

One of the factors influencing SARS-CoV-2 infection is comorbidity. Diabetes mellitus is a comorbidity with a high mortality rate. Poor glucose control in patients can affect cellular immune responses and increase morbidity and mortality associated with infections. The severity of COVID-19 is classified into 5 levels: asymptomatic, mild, moderate, severe, and critical. HbA1c is a good test for identifying the diabetes status of COVID-19 patients. According to the American Diabetes Association, HbA1c levels are considered controlled if <7% and uncontrolled if ≥7%. This study aims to analyze HbA1c levels in COVID-19 patients with diabetes mellitus from 2020 to 2022. This study uses the productive age category (15-64 years). To determine the relationship between HbA1c levels and the severity of COVID-19 patients with diabetes mellitus at Haji General Hospital, East Java Province, from 2020 to 2022. This research employs a cross-sectional, analytical observational method with a consecutive sampling technique involving 96 hospitalized COVID-19 patients. Data collection was conducted through medical record observation. The majority of the samples were male, with an average age of 53 years. The Fisher Exact Test yielded a p-value of 0.13, which is greater than the significance level (0.05), indicating no significant relationship between HbA1c levels and the severity of COVID-19 in diabetic patients. There is no significant relationship between HbA1c levels and the severity of COVID-19 in diabetic patients at Haji General Hospital, East Java Province.

Page 23 of 31 | Total Record : 301

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