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Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Published by Universitas Muhammadiyah Surabaya
ISSN : 25412272     EISSN : 25489526     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 301 Documents
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A literature review of current surgical treatment for congenital pseudoarthrosis of the tibia Panji - Sananta; Ade Yahya Nasution; Eka Noviya Fuzianingsih
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.19066

Abstract

Congenital pseudarthrosis of the tibia (CPT) is an infrequently observed condition. However, it is considered to be one of the most complex ailments in the field of pediatric orthopedics. In cases where a tibial fracture is absent, the conventional treatment approach involves using bracing as a preventive measure against fractures. Various surgical modalities have been proposed for the management of CPT, including intramedullary (IM) rod fixation, external fixators, on-lay grafts, cancellous grafts, periosteal grafts, Paley cross-union, amputation, vascularized fibula grafts, and induced membrane techniques. These modalities can be used in different combinations and permutations. The need for repetitive surgical interventions due to unsuccessful therapeutic outcomes or modifications in secondary treatments can significantly disrupt the childhood experience, resulting in prolonged and recurrent functional limitations. In certain instances, amputation may be required as a primary or secondary treatment modality. This literature review will clarify the current surgical interventions for CPT disease based on a summary of research data. The surgery the patient receives significantly impacts their general health and capacity to heal.
Bilateral renal artery stenosis in pediatric patient with Post-Streptococcal Glomerulonephritis in children: A case report Nieken Susanti; Irma Nur Sukmawati
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.20048

Abstract

The immune-complex mediated inflammation known as post-streptococcal glomerulonephritis (PSGN) was once thought to be one of the most common causes of acute nephritis in children. In this case, we present a 12-year-old girl experiencing symptoms of cough phlegm, congested breath, change of urine color, decreased urine production, as well swelling in the area face and legs after experiencing fever, pain swallowing, cough, and runny nose 3 weeks before admission. On physical examination, the pressure blood was 130/80 mmHg. In addition, the palpebral and extremity were edema bilateral, hyperemia of the tonsil and pharynx, enlarged tonsils T2/T3, and detritus were found. Laboratory and Imaging Tests: hematology; leukocytes 12,930, albumin 2.4 g/dl, on urinalysis, obtained urine cloudy, brownish, leukocyturia, hematuria, and proteinuria, there was also an increase in ASTO titers, abdominal ultrasound found bilateral renal artery stenosis and nephritis bilateral acute. The patient in this case presented with bilateral renal artery stenosis, which is a rare finding in PSGN cases. Management of PSGN include bed rest, low salt diet, fluid balance, as well supportive treatment with IVFD D5 ½ NS 15 drops/min (micro), Antibiotics injection of Ceftriaxone 1 gram/12 hours on the first day and continued with oral Erythromycin 4x500mg, injection prednisolone 3x1, injection Furosemide 1x1 amp, oral spironolactone and sublingual nifedipine, and hypoalbuminemia correction. Prognosis in patients with the given GNAPS governance optimally will give good results.
A literature review of diagnosing transient synovitis hip disease: English Panji - Sananta; Agung Ismanuworo; Eka Noviya Fuzianingsih
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.20329

Abstract

Transient synovitis (TS), an abrupt, non-specific synovium inflammation, is the most prevalent cause of pediatric hip discomfort. Transient synovitis affects 3–10-year-olds. This disease is benign and self-limiting, but clinicians must distinguish it from an acute infection. After ruling out other causes of hip discomfort and limping, clinicians detect transient synovitis. Based on the patient's history, physical examination, and hip radiography, septic arthritis (SA) and TS care are the most likely causes. Clinicians must consider clinical factors and order appropriate lab and imaging tests to rule out alternative illnesses. This review aims to determine how to propose TS hip disease. The databases used were Scopus and PubMed. We included seven articles in our review. Clinical symptoms, lab testing, and radiographs determine the diagnosis. Ultrasound is a useful TS diagnostic tool since it is widely available, and children are not directly exposed to ionizing radiation. If TS and SA illnesses, which are commonly linked, are unclear, detecting bone marrow abnormalities, soft tissue lesions, synovial enhancement, and joint effusion by MRI can be beneficial. Laboratory tests help distinguish TS from SA because there are more extensive evaluations. Additionally, the healthcare provider performs a hip joint aspiration examination under ultrasound or fluoroscopy.
Acute kidney injury induced by beta-lactam antibiotics in children: A scoping review Astalitha Lorel Tania; Alya Ayu Tazkia
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.20376

Abstract

Antibiotics are the agents that cause Acute Kidney Injuries (AKI) in children. A recent study has shown the incidence of nephrotoxicity by antibiotics reaches 16% in children. Beta-lactam types are not widely known for their nephrotoxic effect. This study aims to examine beta-lactam antibiotics' role in inducing children's renal failure. This search for a scoping review on the effect of beta-lactam antibiotics in children was carried out in December-January 2022-2023. We used some search engines with the year of publication 2012-2022 then extracted. The keyword combinations used are: “beta-lactams” OR “β-lactams” AND “acute renal failure” OR “acute renal injury” OR “nephrotoxic” OR “nephrotoxicity” AND “children” OR “pediatric” OR “neonate” NOT “adult”. Studies were excluded if the: (i) adult; (ii) were a review, systematic review, or meta-analysis; (iii) written in a language other than English; (iv) not available in full text; (v) have kidney disease before (vi) in vitro or in vivo. The article selection process was based on PRISMA-ScR. From 4032 articles that met the search criteria, 3 studies met the inclusion criteria. The result shows that beta-lactam increases the risk of acute renal injury in children. This review emphasizes the importance of choosing kidney-safe antibiotics for children.
Exploring cytokine levels in pregnancy, preeclampsia, and sepsis-complicated preeclampsia Mira Kusuma Wardhani; Harry Kurniawan Gondo
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.20427

Abstract

Around the world, preeclampsia (PE) influences five to eight percent of pregnancies and contributes significantly to maternal mortality. This study applies a scientific observational cross-sectional review to examine how TNF-α, TNF-R1, and TNF-R2 play their roles in normal pregnancy, preeclampsia, and preeclampsia associated with sepsis. Blood tests were gathered from subjects at a local medical clinic in Malang, Indonesia, and TNF-α, TNF-R1, and TNF-R2 levels were surveyed utilizing the Enzyme-linked Immunosorbent Assay (ELISA) strategy. The results demonstrate raised TNF-α levels in both preeclampsia and preeclampsia with sepsis, along with expanded TNF-R1 and TNF-R2 receptor levels, signifying their association in these circumstances. Validation through bigger scope studies is basic, possibly situating TNF-α as an early indicative biomarker for sepsis. This study highlights the importance of TNF-α in pregnant mothers with preeclampsia and preeclampsia muddled by sepsis, uncovering possible analytic and remedial avenues.
Determination of ABO blood group based on secretors or non-secretors analysis in body fluids Fery Setiawan; Ahmad Yudianto; Arif Rahman Nurdianto; Jenny Sunariani; Latief Mooduto
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.20561

Abstract

Criminal acts often leave traces analyzed by law enforcement, especially by the Indonesian National Police (POLRI). Sometimes, various items were found and analyzed to link the victim and the perpetrator. Blood, the most abundant body fluid, found in crime scenes, consists of cellular and liquid elements. The forensic focuses on red blood, which can be wet or dried at the crime scene. Sometimes, there was no blood or bloodstains found, but objects related to other body fluids, such as: condoms, toothbrushes, the mouth of glass cups, straws, etc, could be found. Blood group analysis could still be carried out based on secretor gene (Se) considering that 80% of the population was of the secretor group. There are two chromosomes related to blood regulation, namely: chromosomes no. 9 and 19. The former relates to the ABO blood group and the latter relates to the secretory phenotype. The basic principle of secretors was antigens found on the surface of red blood cells and all body fluids, except cerebrospinal fluid. The pattern of inheritance on chromosomes 9 and 19 is based on the probability law by Mendell. It stated that all of genotypes (homozygous dominant-recessive or heterozygous) would be passed on to their offspring.
The effect of using the smartphone blue light filter feature on tear production Ahmad Ikliluddin; Adey Rahmat Saputra
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.21060

Abstract

Smartphones today have been used to support human activities. It makes the human eye always exposed to smartphone screens that use light-emitting diodes (LEDs) that emit light with a blue electromagnetic spectrum known as blue light. The effect of blue light on human eyes is still being studied. This study aims to determine the effect of using smartphone blue light filter features on tear production. This was a quasi-experimental, pre-post study, involving 40 samples who met the inclusion and exclusion criteria. Subjects were asked to use a smartphone within 1 week without activating a blue light filter. After this, tear production was measured using the Schirmer test under topical anesthesia. Then, subjects were asked to use a smartphone again within 1 week by activating the blue light filter and being measured again using the Schirmer test under topical anesthesia. Data obtained were analyzed using SPSS 25 software. There was a statistically significant (sig=0.000) difference in Schirmer test values before and after the usage of smartphone blue light filters. Each increase in the duration of smartphone usage for one minute will decrease Schirmer test results by 0.000625 mm, and so will the multiplication. The duration of smartphone usage has a 21.6% contribution of influence on the results of the Schirmer test. In conclusion, there is an effect of using the blue light filter feature on tear production between the use of a smartphone without activating the blue light filter with the use of a smartphone that activates the blue light filter feature.
Medical education in clerkship: From here and out Bintang Arroyantri Prananjaya; Zain Budi Syulthoni; Ziske Maritska; Lathifah Nudhar; Syarifah Aini; Puji Rizki Suryani; Diyaz Syauki Ikhsan
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.21094

Abstract

The COVID-19 pandemic has changed many things in the medical education system. This change requires adaptation and modification from education providers, teachers, and students. A virtual learning system has been implemented instead of a face-to-face learning system. However, this makes several challenges and issues that must be considered. Virtual learning is considered less attractive and interactive and not effective in teaching clinical skills. For student clerks, the reduced time to undergo education in the hospital leads to fewer case exposures. Another problem is the facilities and infrastructure. Several ways to solve this problem have been implemented while minimizing risk and taking strict precautions. Some institutions modify and innovate to maximize the effectiveness of learning activities. In addition to technical and effectiveness issues, changes in the education system also have an impact on the mental health of medical students, therefore it is important for institutions to be sensitive to changes and risks to students' mental health during the pandemic.
Positive Effect of Konjac Glucomannan on Lowering Blood Pressure in Hypertensive Wistar Rats Bryan Anggara Putra; Sugeng Mashudi; Alfia Pradita Sari; Fany Risma Afriani; Yaya Sulthon Aziz; Tukimin bin Sansuwito
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.21297

Abstract

Hypertension is a non-communicable disease that is currently a top priority for global health. Commonly offered anti-hypertensive pharmacological therapies such as ACE-inhibitors are known to have side effects in long-term use, unlike herbal glucomannan, which has been used as a treatment for patients with type 2 diabetes. The purpose of this study was to see what effect applying glucomannan supplements for 6 hours had on blood pressure parameters obtained from the wistar rat subjects who had hypertension. Twenty five male Wistar rats with normal systolic blood pressure (sBP) ± 110 mmHg were involved in the study; they received a 10% high salt diet for 14 days. They were divided into 4 groups: the positive control group G1 received captopril at 25 mg/kg of body weight and the treatment groups G2  50 mg KGM. Blood pressure measurement using sphygmonanometers with diastolic blood pressure (dBP) is the exclusion criterion of the study. Data analysis is done with a paired sample t-test. Blood pressure in each group decreased after 6 hours of intervention, but the most significant results were obtained in the G5 group that received glucomannan 100 mg/kg bb. In conclusion, Glucomannan can lower blood pressure; this potential is the same as that of red ginger, which modulates the production of angiotensin-corventing enzymes.
Anxiety Level of Pregnant Women at Siti Khodijah Muhammadiyah Sepanjang Hospital During COVID-19 Pandemic Ninuk Dwi Ariningtyas; Aulia Nuril Islamy; Roni Subagyo; Muhammad Anas
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.21374

Abstract

Pregnant women are one of the vulnerable groups who have to face the unpleasant effects of the COVID-19 pandemic. One of the effects is the psychological impact that is bad for both the mother and the fetus. This study aims to describe the level of anxiety experienced by pregnant women during the COVID-19 pandemic at Siti Khodijah Muhammadiyah Sepanjang Hospital. The results of this study are expected to be used as information to help overcome more serious mental health problems. This research uses using quantitative descriptive design with a cross-sectional approach. The sample of this study was 112 pregnant women who met the research criteria. This research was conducted by giving them questionnaires consisting of their age, job, parity, gestational age, history of COVID-19 illness, history of mental problems, knowledge about COVID-19, and level of anxiety. Statistical analysis showed 84.8%, 8.9% and 6.3% of pregnant women experience low, moderate, and concerning levels of anxiety, respectively. The majority of pregnant women are primigravida, aged 20-35 years, with a gestational age of 28-41 weeks, housewives, and the level of knowledge about COVID-19 is very good. Correlation analysis using Kendall's tau-b showed a significance value of 0.038 (<0.05), which means a relationship exists between the level of knowledge about COVID-19 and the level of anxiety of pregnant women. In conclusion, the level of anxiety of pregnant women the most is low anxiety, followed by moderate and concerning levels of anxiety.

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