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Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Published by Universitas Muhammadiyah Surabaya
ISSN : 25412272     EISSN : 25489526     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 301 Documents
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Karakteristik Pasien Tuberkulosis Paru Dengan HIV di Rumah Sakit Umum Daerah Dr Harjono Ponorogo Periode Januari 2018 - Desember 2022 Anindya Zalfaa Kusuma Dewi; Ronald Pratama A.; Dody Taruna; Irmawati M. Dikman; Soedarsono Soedarsono; Yelvi Levani
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.21666

Abstract

Tuberculosis (TB) is the most common opportunistic infection in people living with HIV/AIDS in Indonesia, and HIV infection promotes Mycobacterium tuberculosis infection. In ODHIV, the probability of contracting TB is 10% per year. According to the Indonesian Ministry of Health, East Java is in second place with 71,909 cases and has the second highest number of AIDS patients and 824,000 TB cases in Indonesia. This study aims to determine the characteristics of pulmonary tuberculosis patients with HIV at DR Harjono Ponorogo Hospital for the period January 2018 - December 2022. This study applied descriptive research methodology with quantitative techniques with secondary data from medical records of pulmonary TB patients with HIV at Dr. Harjono Ponorogo Hospital for the period January 2018 - December 2022.  The results showed a total sample of 130 medical records, there were several characteristics of TB patients with HIV, namely the highest age group of 30-39 years by 29.2%, more in male gender 73%. More patients had last high school education 38.5%, more treatment duration in patients who did for 9 months 61.5% and the results showed more patients with poor prognosis 56%. In conclusion, the characteristics of TB patients with HIV with the highest group at the age of 3-39 years, having male gender, more high school education, with more treatment duration of 9 months, and the results showed a poor prognosis.
Hubungan Kecanduan Gawai dengan Kejadian Insomnia pada Mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Surabaya Gina Noor Djalilah; Lucky Dyah Oktaviyanti; Era Catur Prasetya; Nina Devi Indrawati; Adi Satria Nugraha
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.22069

Abstract

Insomnia is a condition characterized by difficulty falling asleep, staying asleep, or waking up early despite having the opportunity to sleep. Insomnia can reduce the quality and quantity of sleep, leading to various negative effects on an individual's health and well-being. One of the potential causes of insomnia is excessive smartphone use, which can lead to addiction. Smartphone addiction can affect people of all ages, from children to adults. It has been associated with several adverse effects, including insomnia, recurrent and prolonged headaches, and fatigue. This study aimed to investigate the relationship between smartphone addiction and insomnia among medical students at the University of Muhammadiyah Surabaya. This cross-sectional observational study involved 87 medical students from the 2019, 2020, 2021, and 2022 cohorts. The sample was selected using a proportionate stratified random sampling technique. Data were collected using the Smartphone Addiction Scale (SAS) and the Insomnia Rating Scale (KSPBJ-IRS) through a Google form. The data were analyzed statistically using the Chi-square test in SPSS version 25. The Chi-square test showed a p-value of 0.005 (<0.05), indicating a statistically significant relationship between smartphone addiction and insomnia among medical students at Muhammadiyah University of Surabaya. In conclusion, the study found a significant relationship between smartphone addiction and insomnia among medical students at Muhammadiyah University of Surabaya. This suggests that excessive smartphone use may contribute to sleep disturbances in this population.
Prevalence And Pattern Sensitivity Multidrug Antibiotics Resistant Pseudomonas aeruginosa in the High Care Unit at Dr. Soetomo General Academic Hospital Period 2022-2023 Ratna Kusumawati; Eko Budi Koendhori; Ni Made Mertaniasih; Irfan Arif Ikhwani; Dimas Firman Hidayat; Yelvi Levani; Ayu Lidya Paramitha
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.22152

Abstract

The prevalence of Multidrug antibiotic-resistant Pseudomonas aeruginosa (MDRPA) has been increasing during the decade And has become attention in hospital patients. This retrospective descriptive descriptive aimed to determine the prevalence of MDRPA and its sensitivity patterns. Data were taken from results of bacterial culture and antibiotic resistance tests from various clinical specimens from patients at Dr. Soetomo General Academic Hospital throughout 2022-2023. The resistance test was carried out using a Vitek 2 compact instrument. MDRPA is defined as Pseudomonas aeruginosa that is not sensitive to three or more of the following classes of antibiotics: meropenem or imipenem, ciprofloxacin, gentamicin or amikacin, ceftazidime or cefepime, and piperacillin/ tazobactam. The prevalence of MDRPA was 57.0%. MDRPA isolates were also the most common origin from the burn unit and HCU A (high care unit A), mostly from pus specimens and sputum. Pseudomonas aeruginosa sensitivity was best with piperacillin/tazobactam (55.5%), meropenem (54.8%), amikacin (47.5%), gentamicin (46.5%), cefepime (46.3%), ceftazidime (45.0%), ciprofloxacin (44.7%) and aztreonam (43.2%). The sensitivity of MDRPA to antibiotics is much lower than that of Pseudomonas aeruginosa. This study showed high number of MDRPA specifically in Surabaya and the pattern sensitivity of Pseudomonas aeruginosa can become guidelines in choosing antibiotics treatment for patients.
Polymorphic CAG and GGN repeats in Cryptorchidism patient risk: A meta-analytical study Nurul Cholifah Lutfiana; Athaya Febriantyo Purnomo; Nur Aisah Ibrahimiyah
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.22603

Abstract

Genetic mutations in the androgen receptor (AR) gene have been identified as the cause of androgen insensitivity syndrome. These mutations are linked to inconsistent development of the Wolffian duct and may result in conditions such as micropenis, hypospadias, and cryptorchidism. The androgen receptor has two polymorphic sites located in exon 1, which consists of varying amounts of CAG and GGN repeats. These repetitions lead to the formation of polyglutamine and polyglycine stretches of varied lengths. Increased CAG repeats lead to a decrease in androgen receptor transcriptional activity, but the impact of GGN triplets is less well understood. This research examined the CAG and GGN repeat lengths in males who had a past medical record of cryptorchidism. Prospective and retrospective observational studies from PubMed, Science Direct, and Embase were systematically searched up to 15th November 2020. Primary outcomes were analyzed using a fixed or random effect model regarding its heterogeneity and continued with multilevel modeling of each polymorphism and ethnicity. CAG and GGN repeat polymorphism was found to be significantly different compared to control in contributing to cryptorchidism (CAG: 0.55 [CI 95%=0.19-0.91]; p-value=0.003 and GGN 0.90 [CI95%=0.65-1.15]; p value<0.000).  In conclusion, CAG and GGN repeat polymorphism have an essential role in the incidence of cryptorchidism.
Levels of Stress, Anxiety, and Depression in Tourism Workers in the Bali Province During the COVID-19 Pandemic Anak Agung Sagung Ayu Tribhuwana Wulan Nadarin; Putu Indah Budi Apsari; Made Indra Wijaya
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.19549

Abstract

Stress, anxiety, and depression in tourism workers have increased during the COVID-19 pandemic, which are mental health problems that need to be watched out for. Mental health has become one of the most significant problems in the world, including Indonesia, especially during the COVID-19 pandemic. Seeing the significant role of mental health disorders in tourism workers accompanied by stress, anxiety, and depression can have an impact on the health of human resources in the tourism sector. The purpose of this study was to determine the level of stress, anxiety, and depression in tourism workers in the province of Bali during the COVID-19 pandemic. The sample of this study was 103 people aged 18-60 years who are active tourism workers in the Province of Bali, which was selected by convenience sampling using Google Forms. The research method was cross-sectional and analyzed using SPSS version 27. The study results showed that most of the research samples experienced severe stress, as many as 38 (36.9%). The majority of the study sample experienced very severe anxiety with 74 people (71.8%). Most of the research samples experienced very severe depression, with 65 respondents (63.1%). In conclusion, tourism sector workers suffer severe stress, anxiety, and depression during the COVID-19 pandemic.
Osteopontin and Its Clinical Correlation to Type 1 Cardiorenal Syndrome: A Literature Review Yongki Welliam; Citrawati Dyah Kencono Wungu; Hendri Susilo
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.20878

Abstract

Cardiorenal syndrome (CRS) is a spectrum of disorders involving both the heart and the kidneys, either acutely or chronically, in one organ that can lead to dysfunction in the other. Type 1 CRS, the most common CRS, is when acute heart dysfunction impacts acute kidney dysfunction, commonly known as acute kidney injury. Comorbidities involving these two significant organs contribute to a high patient mortality rate that requires a new potential diagnostic method. Biomarkers are one of the diagnostic modalities widely used in various diseases. Osteopontin (OPN) is a phosphorylated glycoprotein found primarily in bones and teeth that regulates mineralization. Osteopontin is known to be involved in describing various pathological changes in the body, including cardiovascular diseases. This review aims to evaluate the clinical correlation of OPN level changes with the occurrence of Type 1 CRS. The results indicate that OPN also plays a role in detecting the progression of cardiovascular disease towards renal injury. The imbalance in the function of OPN as a pro-inflammatory and anti-inflammatory agent increases the progression of kidney disease in patients. Further findings suggest that, more specifically, urinary OPN describes renal injury events in type 1 CRS patients.
Unraveling the intricacies: understanding the complexities of obesity, body image, and demographic influences among Indonesian high school adolescents Harsono Wiradinata
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.20883

Abstract

This research addresses Indonesia's significant obesity issue among teenagers, highlighted by the 2022 Indonesian Health Survey. It explores the correlation between overweight-obesity prevalence and body image disturbances in high school adolescents, with a sample of 185 individuals selected through random sampling. Inclusion criteria involve parental consent for overweight-obese adolescents, while exclusion criteria consider specific health conditions or unwillingness to participate. Ethically, respondent anonymity and the lack of biological materials alleviate concerns. BSQ-34 prevalence rate analysis reveals a complex landscape influencing body image disturbances. While age and gender show limited associations, Body Mass Index correlates significantly, emphasizing its role. Conversely, no notable correlation is found with bullying, parenting styles, and social comparison, highlighting the independence of body image disturbances. Media influence stands out, warranting comprehensive investigations. In conclusion, these findings stress the complexity of body image concerns, advocating for holistic comprehension and interventions beyond singular influences, emphasizing the multifaceted nature of factors affecting high school adolescents' body image perceptions.
Analysis of Neutrophil, Leukocyte, Lymphocyte, and NLR Cell Profiles in Patients Diagnosed with Chronic Gastritis Affected by Helicobacter pylori and Non-Helicobacter pylori Infection at Dr. Soetomo Hospital in Surabaya, Indonesia Nahdah Aulia Aziz; Manik Retno Wahyunitisari; Imam Susilo
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.21260

Abstract

Helicobacter pylori (HP) is a prevalent cause of bacterial infections, particularly chronic gastritis in the human body. The diagnosis of gastritis relied on gastric biopsy examination, where inflammation is characterized by an increase in various inflammatory cells, including macrophage, neutrophil, lymphocyte, or plasma cells. Therefore, this research aimed to determine the profiles of neutrophil, leukocyte, lymphocyte, and neutrophil lymphocyte ratio (NLR) in chronic gastritis patients, distinguishing between those with Helicobacter pylori and non-Helicobacter pylori infection at Dr. Soetomo Hospital in Surabaya. This research adopted a retrospective method, using medical records for chronic gastritis patients at Dr. Soetomo Hospital between 2018 and 2022. The variables analyzed included Helicobacter pylori infections and values of neutrophil, leukocyte, lymphocyte, and NLR cells. The obtained data were subjected to analysis using descriptive statistics. The results showed that the majority of participants were females (61.9%), senior high school graduates (52.38%), and aged 45-59 (pre-elderly) (32.14%). In non-Helicobacter pylori group, the average values of neutrophil, leukocyte, lymphocyte, and NLR cells were 62.29 (SD = 12.17), 8.155 (SD = 4.02), 29.165 (SD = 12.31), and 3.68 (SD=4.865), respectively. In conclusion, females showed a propensity for chronic gastritis with Helicobacter pylori. It was observed that non-Helicobacter pylori chronic gastritis tended to have elevated neutrophil and leukocyte values. Meanwhile, Helicobacter pylori-related chronic gastritis tended to show increased lymphocyte and NLR values due to systemic inflammation. Helicobacter pylori was associated with conditions such as iron deficiency anemia, cardiovascular disease, diabetes, thyroid disease, and malnutrition.
Pilihan Antibiotik Pada Pasien Abses Hepar Piogenik Ilham Ramadhana Mukti; I Wayan Bagoes Vidananda; Ihzani Rahmaningtyas; Ilyas Hasanovic; Imtiyaz Tsany; I Wayan Suryajana; Rudi Pandapotan Napitupulu; Mukti Fahimi
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.21290

Abstract

Pyogenic liver abscess is a dangerous, life-threatening disease with a high mortality rate that requires accurate diagnosis and treatment. The most common symptoms are upper abdominal pain, hepatomegaly, high fever, nausea, and vomiting. Pyogenic liver abscess occurs due to infection from anaerobic bacteria or aerobic bacteria. in the United States the reported annual incidence is 3.6 cases per 100,000 people. But in Taiwan it is 17.6 per 100,000 people. Pyogenic liver abscess sufferers are dominated by men but currently it affects older people more, with the most cases aged 50 to 60 years. The purpose of this study was to know the choice of antibiotics in patients with pyogenic liver abscess. Empiric antibiotics should be initiated immediately upon suspicion of a pyogenic liver abscess tailored to kill all possible bacteria: Gram-negative cocci, gram-positive cocci, and anaerobes. Antibiotic regimens include amoxicillin-clavulanic acid, third-generation cephalosporins combined with aminoglycosides, or piperacillin/tazobactam. In cases of penicillin allergy or antibiotic resistance, fluoroquinolones or carbapenems may be used.
The relationship of body mass index, mid-upper arm circumference, and waist circumference with the blood pressure in elderly indriyani indriyani; Rury Tiara; Noviyanti Noviyanti; Cintiya Aprilia
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.21888

Abstract

Life expectancy is one of the most popular summary measures for a population's general health. Growing Life Expectancy predicts a rise in senior citizens in the coming years. An increase in health issues among the elderly may result from an aging population. Anthropometric measures of nutritional status can reveal nutritional status, which may contribute to the development of cardiovascular risk; however, research on this topic in the elderly is still lacking. This study uses a cross-sectional design and a sample size of 60 elderly people who live in Muhammadiyah University Palembang's development village. Blood pressure and anthropometric measures were taken by researchers. Throughout the course of five minutes, three separate readings of the blood pressure, waist circumference, mid-upper arm circumference, and body mass index (BMI) were obtained. The means of these measurements were then analyzed. Diastole Blood Pressure/DBP was substantially correlated with BMI, WC, and MUAC (P = 0.001; r = 0.407; P = 0.003; r = 0.381 & P = 0.017; r = 0.307, respectively). In conclusion, systolic and diastolic blood pressure in the elderly are positively associated with anthropometric measures of body fatness, particularly BMI.

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