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JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
ISSN : 20888139     EISSN : 24432946     DOI : -
Core Subject : Health,
JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts in both English (preferably) and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. JMPF is also open for various fields such as pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, goverment policies related to pharmacy, and pharmaceutical care.
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Articles 487 Documents
Educational Video to Improve Glycemic Control of Type 2 Diabetes Mellitus Patients Nora Wulandari; Daniek Viviandhari; Afi Seli Febriani
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.59387

Abstract

Glycemic control is a critical point in the management of type 2 diabetes mellitus (T2DM). The limited number of pharmacists in primary health care in Indonesia is one of the reasons that a simple alternative method is needed for managing T2DM patients. Objective: This study aimed to measure the effectiveness of an education diabetes video as a simple method of improving glycemic control of T2DM patients. Methods: This was a quasi-experimental pre-test/post-test study involving T2DM patients from one randomly selected public healthcare centre in East Jakarta. Glycated haemoglobin (A1C) levels were examined before and 12 weeks after the video intervention. Results: Thirty of T2DM patients enrolled in this study. The educational video was found to decrease the A1C level significantly (p = 0.001) from an average±SD of 7.930±1.262 to 5.517±0.614. Conclusions: This study found the educational was effective at improving the glycemic control of patients with T2DM. However, further investigation with control group still needed to confirm that the video that did it.
Apa yang direkomendasikan apoteker untuk tatalaksana diare akut pada anak? Sebuah survei di wilayah timur Kota Surabaya Linda Fidya Ningsih; Adji Prayitno Setiadi; Abdul Rahem; Cecilia Brata; Yosi Irawati Wibowo; Eko Setiawan; Steven Victoria Halim
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.59719

Abstract

Appropiate recommendation provided by pharmacists is considered as a crucial factors to prevent morbidity and mortality among children with acute diarrhea in the community. This study aimed to determine the type and the appropriateness of recommendations provided by the community pharmacists in the eastern part of Surabaya to children presenting with acute diarrhea. This was cross-sectional study conducted by using a questionnaire consisting of questions about participants’ characteristics and a case of acute diarrhea in children without complications and other “alarm symptoms” requiring medical referral. The appropriate recommendation for the case was to give a combination of oral rehydration solution (ORS) and zinc with or without other recommendations. Data were analyzed descriptively using SPSS version 22. A total of 84 pharmacists provided consent to be participants in this study. The majority of participants (73,81%) were pharmacists manager and more than 50% of them completed pharmacist professional degree between 2010 and 2019. Type of pharmacists’ recommendations were further classified as: medical referral, provision of medicine, laboratory testing, and non-pharmacology treatment. The most provided recommendations were provision of medicine (97,62%) with or without other recommendations. Medical referral were recommended by 22 pharmacists (26,19%). Of the total participants, 13,09% provided appropriate recommendations. Findings of this study indicate the necessity to optimise the role of community pharmacists in managing acute diarrhea in children. Further study to identify the needs of community pharmacists, either conducted with qualitative or quantitative approach, is required as the key step before implementing further intervention.
Uji Perbandingan Antibiotik Profilaksis Ceftriaxone versus Cefazolin pada Bedah Obstetri dan Ginekologi Asri Rahayu; Fita Rahmawati; Tri Murti Andayani; Ammar Siradjuddin
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.59779

Abstract

Surgical site infection (SSI) is the most common complication in postoperative surgical patients which is associated with high morbidity, mortality, and cost burden. These complications can be prevented by giving proper prophylactic antibiotics. Cefazolin is a recommended prophylactic antibiotic, but in the practice in Indonesia hospital, there are still many uses of ceftriaxone. This study aimed to compare the clinical outcome and safety of cefazolin and ceftriaxone as prophylactic antibiotics in preventing SSI in obstetric and gynecological surgical patients. The study design was double-blind randomized controlled trial. The data collection was conducted from January to June 2020 at dr. Dradjat Prawiranegara Regional Hospital Serang. A total of 82 subjects who met the inclusion criteria were divided into two groups by block randomization, 41 subjects were given cefazolin and 41 subjects were given ceftriaxone. The clinical outcome was measured by preventing SSI for the effectiveness and side effects for safety outcomes in both groups. The comparison of effectiveness and side effects were analyzed using the bivariate test (chi-square or fisher’s exact test) and relative risk (RR). The study showed that the effectiveness of cefazolin was the same as ceftriaxone in preventing SSI for 30 days (RR= 0.89; p= 0.724; 95%CI: 0,193-3,133) with the number of SSI 12.2% vs 9.8%. Side effects included nausea, vomiting, and phlebitis was observed in the administration of antibiotic by intravenous push (IVP) pre-operating.  Cefazolin have safetier than ceftriaxone with the incidence of side effects were 9.8% vs 29.3% ((RR = 0,33; p= 0.003; 95% CI: 0.076-0.895).  Cefazolin is an antibiotic recommended by Indonesian Ministry of Health and the Association of Obstetrics and Gynecology.  This study encourages the use of cefazolin to prevent resistance due to ceftriaxone to overuse.
Kajian Adverse Drug Reactions Terkait Interaksi Obat di Bangsal Rawat Inap Rumah Sakit Akademik UGM Fivy Kurniawati; Nanang Munif Yasin; Amila Dina; Sanses Atana; Sarah Nabila Hakim
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.60228

Abstract

Adverse Drug Reactions (ADRs) is one of the causes of patient’s prolonged length of stay in the hospital and drug interactions can be included as one of the causes of the cause of ADRs. ADR related to drug interactions is a clinical problem that requires proper prevention. This study aimed to identify potential drug interactions also identify adverse drug reactions (ADRs) related to drug interactions in hospitalized patients at Universitas Gadjah Mada Teaching Hospital. This cross-sectional study used retrospective data collection through patient’s medical records from January to June 2018. Patients included in this study were all patients who received therapy more than two kind of drugs simultaneously treated in hospital wards of Universitas Gadjah Mada Teaching Hospital, Yogyakarta, Indonesia. The data collected were then analyzed descriptively. Drug interactions were analyzed using Drug Interaction Facts 2012 and Stockley. ADRs were analyzed by monitoring documented effects of patients with potential drug interaction. There were 115 of 362 patients (31.8%) with potential drug interactions. The total numbers of potential interactions that occur were 182 interactions. The most potential type of interaction was the interaction with moderate severity, with 115 interactions (63.2%). The majority of drug interactions occur through unknown mechanisms (54.4%). Actual ADR occurs in 3.3% patients who were 2 pediatric patients and 4 geriatric patients. This study can be a reference for drug interactions and ADRs as well as guide for pharmacist and healthcare in providing the right medication.
Outpatient Parenteral Antimicrobial Treatment sebagai Upaya Menurunkan Biaya Pasien Ulkus Diabetik yang Terinfeksi Hemi Sinorita; Rizka Humardewayanti Asdie; Tri Hartati; Pebriati Sumarningsih; Titik Rahayu; Ika Puspitasari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.60256

Abstract

Ulkus diabetik  terinfeksi memerlukan terapi antibiotik yang tepat untuk menghindari risiko amputasi. Tujuan utama program Outpatient Parenteral Antimicrobial Treatment (OPAT) adalah memungkinkan pasien memperoleh terapi antibiotik parenteral dengan aman dan efektif tanpa menjalani rawat inap. Penelitian ini bertujuan untuk mengetahui perbedaan biaya pemberian antibiotika parenteral dan kualitas hidup pasien antara pasien ulkus diabetik terinfeksi yang memperoleh pelayanan rawat inap dan OPAT. Penelitian ini menggunakan rancangan penelitian ini adalah quasi experimental pada pasien ulkus diabetika yang terinfeksi di di RSUP dr. Sardjito Agustus 2019 sampai April 2020 dengan kriteria inklusi pasien umur ≥ 18 tahun; kondisi klinis stabil; sudah didapatkan hasil kultur swab dasar luka, dengan kriteria eksklusi pasien imunocompromised (pasien kanker dan pasien transplantasi organ yang mendapatkan terapi imunosuppresan serta pasien HIV). Pasien mendapat perawatan luka dua kali dalam seminggu di poliklinik endokrin untuk dinilai outcome klinisnya dan pada akhir pengobatan mengisi kuisioner kualitas hidup SF36. Selanjutnya dihitung biayanya dan dianalisa perbedaan kualitas hidup serta biaya antara OPAT dibanding rawat inap. Selama penelitian terdapat 15 pasien kelompok OPAT dan 15 pasien kelompok rawat inap. Dari sisi perbaikan klinis terdapat perbedaan yang bermakna antara skor PEDIS kelompok OPAT terhadap kelompok Rawat Inap  (p = 0,007). Pembiayaan pelayanan OPAT menghemat  biaya medik langsung sebanyak 75,77% dari pembiayaan pelayanan rawat inap dengan total pelayanan OPAT sebesar Rp 2.556.117,- dan pelayanan rawat inap sebesar Rp 10.549.487,-. Terdapat  perbedaan yang bermakna pada beberapa domain kualitas hidup  yaitu domain fungsi peran emosional (p=0,045); domain fungsi sosial (p<0,01) dan score MCS (Mental Component Summary (p=0,005). OPAT meningkatkan 3 domain fungsi ini.
Pengembangan Kuisioner Udayana untuk Penilaian Kepuasan Pasien terhadap Pelayanan Kefarmasian oleh Apoteker di Pusat Kesehatan Masyarakat Luh Putu Febryana Larasanty; Made Krisna Adi Jaya; Ketut Widyani Astuti; I Wayan Martadi Santika
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.60998

Abstract

The implementation of pharmaceutical care by pharmacists at the community health center has been regulated in the Minister of Health Regulation No. 74 of 2016. Based on that regulation, assessment of pharmaceutical care services is needed to ensure the quality of services provided by pharmacists. This study aims to develop an Udayana questionnaire that can be used to evaluate the quality of pharmaceutical care provided by pharmacists at community health centers. This research is quantitative (survey implementation) carried out in 2 phases. The first phase is the design of the Udayana questionnaire. The second phase is to verify the validity and reliability of the questionnaire. The questionnaire validity test was carried out in three stages, namely the logical validity test, content validity, and construct validity. The questionnaire statement develop based on Minister of Health Regulation No. 74 of 2016 obtained 31 statements which are divided into 5 dimensions of service quality. The logical validity test resulted in 30 statements that were declared valid by experts. Content validity test is done by calculating the value of the content validity ratio (CVR) and the value of the content validity index (CVI). The CVR and CVI results showed that 7 statements were eliminated because they were not valid (CVR value <0.99 and CVI <70%). Construct validity test and questionnaire reliability were tested on 384 respondents who had met the inclusion criteria. The construct validity test resulted 23 valid statement (r = 0.148). Results of the reliability test based on Cronbach's Alpha value is greater than 0.6, indicating that all the valid statement items in the Udayana questionnaire are reliable. Based on the results of validity and reliability tests, 23 statements of Udayana's questionnaire are stated valid and reliable and can be used to evaluate the quality of pharmaceutical care at the community health center.
A Scoping Review of Disposal of Unused Medicines in Take-Back Programs Mufti Alifia Rahmadani; Susi Ari Kristina
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.61343

Abstract

Unused medicines in the household cause many problems. Medicines take-back programs were established to prevent inappropriate medicines disposal, abuse, accidental poisoning, and help reduce the number of unused medicines in households. A literature search using the keywords “unused AND medicine”, “disposal AND unused AND medicine”, “reasons AND medicine AND disposal”, “medicine AND take-back program” and “cost AND medicine AND take-back program” in PubMed, Science Direct, Scopus and Google Scholar. Articles published in 2010 – 2020 in English report the medicine take-back program with the number of medicines and/or reasons for the return and/or economic value of medicines collected in the medicines take-back program. A total of 16 articles were included in the criteria for this systematic review. Medicines take-back program was majority-owned in the US (69%). Two programs focus on returning controlled medicines. Gastrointestinal, respiratory, cardiovascular, antimicrobial and non-narcotic analgesic were the most common of all medicines returned. The expired medicine and treatment discontinuation by (doctors/prescribers) were the most reason medicine was returned to the medicines take-back program. The total cost of all medicines returned topped $1,118,020. Medicines take-back program was an essential solution to the inappropriate medicine disposal problem. Good coordination was required between the government and other authorities.This medicine take-back issues can help solve the problems of medicine use, storage, and disposal that lead to the country's economy.
Analisis Biaya dan Luaran Klinis Sindrom Koroner Akut Berbasis Clinical Pathway Susan Fitria Candradewi; Dyah Aryani Perwitasari; Nabilah Nabilah
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.51176

Abstract

Health clinicians often show different variations in the choice of therapy they prescribe for patients depending on their expertise, knowledge, and even their art. This is likely to affect several things, including the cost that patients have to pay. Such a difference in costs is avoidable by applying scientific evidence-based medical service standards and having measurable outcomes known as Clinical Pathways. A clinical pathway serves as a tool to measure the quality of health services based on the standardization of the treatment process. This research was designed to determine the cost analysis of treatments received by patients with acute coronary syndrome (ACS) according to the clinical pathway. This non-experimental research employed a retrospective cohort study design. The data were gathered from the medical records of ACS patients who were treated at the ICCU of PKU Muhammadiyah Hospital in Yogyakarta, and the costs incurred were compared between treatments that matched and did not match the clinical pathways. The inclusion criteria were ACS patients treated during 2016 who were between ≥ 18 and <75 years old and had complete data. Meanwhile, the exclusion criteria were ACS patients who had incomplete data, tumor malignancy, and a creatinine level of > 3 mg/dL. Here, therapies given to patients are concluded to fit the clinical pathway if they are precisely the same (100%) as the Clinical Practice Guide used by this hospital. The clinical outcome was measured from the patient’s length of stay (LOS). During the data analysis, the costs of ACS patient treatments that were compliant and non-compliant with the clinical pathway were compared based on the level of severity using the Mann-Whitney test in the SPSS program. The results showed that of the 63 patients, 31 received treatments according to the clinical pathway, while the other 32 did not. The average LOS of the former and the latter were, respectively, 4.45 and 5.53 (p= 0.043), with the total costs of treatments up to IDR5,474,001,73 and IDR6,728,153.13 (p= 0,154). Conformity to a clinical pathway significantly influences the length of stay but does not affect the cost of care for acute coronary syndrome patients.
Kontrol Glikemik dan Profil Serum Kreatinin Pada Pasien DM Tipe 2 Dengan Gagal Ginjal Kronik Emy Oktaviani
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.60323

Abstract

Diabetes mellitus adalah kelainan metabolik yang ditandai dengan hiperglikemia yang jumlahnya terus meningkat sehingga meningkatkan jumlah pengunaan obat antidiabetik dan berisiko menimbulkan efek samping obat terutama pada fungsi ginjal. Penelitian ini bertujuan untuk mengetahui pola penggunaan antidiabetik dan hubungannya dengan kontrol glikemik dan serum kreatinin, serta hubungan kontrol glikemik dengan serum kreatinin pada pasien DM tipe 2 dengan gagal ginjal kronik rawat jalan. Rancangan penelitian ini adalah cross sectional secara retrospektif menggunakan data rekam medik pasien. Kontrol glikemik dilihat dari gula darah puasa (GDP) dan gula darah 2 jam post prandial (GD2JPP). Hasil analisis statistik menunjukkan bahwa dari 83 data rekam medik yang memenuhi kriteria inklusi mengindikasikan bahwa tidak terdapat hubungan yang signifikan antara pola pengunaan antidiabetik oral dengan GDP (p-value=0,546), namun menunjukkan hubungan yang signifikan antara pola pengunaan antidiabetik oral dengan GD2JPP (p-value=0,008) dan serum kreatinin (p-value=0,000). Hasil penelitian juga menunjukan terdapat hubungan yang signifikan antara GD2JPP dengan serum kreatinin (p-value=0,009).Kata Kunci: Diabetes, Kontrol Glikemik, Serum Kreatinin
Pengaruh Pemberian Leaflet Terhadap Pengetahuan Masyarakat tentang Obat Tradisional Ratna Sari Dewi; Fina Aryani; Yelly Hidayani
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.60889

Abstract

Obat tradisional yang mengandung Bahan Kimia Obat (BKO) saat ini masih banyak ditemukan sehingga masyarakat harus waspada dengan meningkatkan pengetahuan tentang obat tradisional seperti informasi minimal yang perlu diketahui ketika membeli sediaan obat tradisional dan cara membedakan sediaan obat tradisional yang legal ataupun ilegal. Penelitian ini bertujuan untuk mengetahui efek pemberian media edukasi leaflet terhadap pengetahuan masyarakat tentang obat tradisional di wilayah Simpang Tiga Kota Pekanbaru. Pengaruh media leaflet dinilai berdasarkan perubahan skor pengetahuan. Metode penelitian yang digunakan adalah quasi experiment dengan rancangan non randomized control group pretest and posttest design yang dilakukan terhadap 70 responden kelompok kontrol (tanpa pemberian leaflet) dan 70 responden kelompok perlakuan (dengan pemberian leaflet). Sampel penelitian adalah masyarakat Simpang Tiga yang dipilih menggunakan teknik convenience sampling sesuai kriteria inklusi dan eksklusi. Instrumen yang digunakan berupa kuesioner untuk mengukur pengetahuan yang telah diuji validitas (diperoleh 17 pertanyaan yang valid) dan reliabilitasnya (r=0,929). Analisis data menggunakan uji Wilcoxon dan Mann-Whitney. Hasil penelitian menunjukkan bahwa terdapat perbedaan yang signifikan pada perubahan skor pengetahuan responden kelompok kontrol dan kelompok perlakuan dengan p value = 0,000. Dapat disimpulkan bahwa pemberian media leaflet sangat berpengaruh terhadap pengetahuan masyarakat tentang obat tradisional di wilayah Simpang Tiga Kota Pekanbaru. Tenaga Kefarmasian harus aktif dalam memberikan edukasi kepada masyarakat tentang obat tradisional dan sebaiknya menggunakan media seperti leaflet.