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JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Published by Universitas Gadjah Mada
ISSN : 20888139     EISSN : 24432946     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts in both English (preferably) and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. JMPF is also open for various fields such as pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, goverment policies related to pharmacy, and pharmaceutical care.
Arjuna Subject : -
Articles 487 Documents
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Drug-Drug Interactions (DDIs) in Elderly Hypertensive Inpatients Titami, Arina; Wiedyaningsih, Chairun; Pramantara, I Dewa Putu
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.101799

Abstract

Background: The prevalence of hypertension is higher among the elderly population. Elderly patients are considered a high-risk population for Drug-Drug Interactions (DDIs) due to multi-morbidity-related polypharmacy, age-related physiological changes, as well as pharmacokinetic and pharmacodynamic changes.Objectives: This study conducted a drug use survey in the inpatient department of the Academic Hospital of Universitas Gadjah Mada Yogyakarta to assess Drug-drug interactions (DDIs) in individual prescriptions for elderly hypertensive patients.Methods: This research employs an observational study design with a retrospective cohort approach. This study was conducted at the Academic Hospital of Universitas Gadjah Mada Yogyakarta in January-December, 2021. The inclusion criteria for this study included patients diagnosed with hypertension, aged 60 years or older and those hospitalized. Ethical approval for this research was granted by the Faculty of Medicine, Public Health and Nursing Research Ethics Commission at Universitas Gadjah Mada, Yogyakarta under approval number KE-FK-0500-EC-2022.Results: 120 prescriptions from 120 patients were collected from the medical records maintained by the Academic Hospital of Universitas Gadjah Mada Yogyakarta. This study identified 66 cases of Drug-Drug Interactions (DDIs), mainly due to drug interactions comprising 8 interactions unrelated to hypertension, and 58 related to hypertension. Three actual drug interaction events resulted in increased blood pressure, while the others were potential drug interactions.Conclusion: From this study, it can be concluded that elderly patients are considered a natural high-risk population for DDIs. Each patient should be assessed individually based on their prescriptions, although in many cases, DDIs are unavoidable.Keywords: Drug-Drug Interactions; Elderly; Hypertension; Inpatients
Direct Medical Costs of Diabetes and the Foot Ulcer Outpatients in A General Hospital, Yogyakarta Untari, Eka Kartika; Andayani, Tri Murti; Yasin, Nanang Munif; Asdie, Rizka Humardewayanti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.90615

Abstract

Background: In addition to the financial burden that Diabetes Mellitus (DM) places on diabetics and their families due to the complications of Diabetic Foot Ulcers (DFU), treatment costs are escalating. Along with the costs associated with diabetic impairments, direct medical costs may contribute significantly to the financial burden of diabetes.Objectives: This study aimed to determine expenditures associated with DFU, identify cost-influencing factors, and compare the costs of patients with DFU and those without ulcers.Methods: To achieve this objective, this study employed a cross-sectional design and included 198 medical records of DM patients who met the following criteria: age range of 18 to 60 years; type 1 or type 2 DM; receipt of anti-diabetics; payment information; absence of autoimmune or end-stage chronic disease; and absence of corticosteroid. The significance of the cost difference between DFU and non-ulcer patients was evaluated using parametric and non-parametric tests as well as linear regression analysis to determine the cost-influencing factors.Results: This study included 188 patients with type 2 diabetes and ten patients with type 1 diabetes. A total of 131 people with diabetes did not have ulcers, while 67 had a history of DFU. The average direct medical expenses for patients with DFU are IDR 760,146.32, compared to IDR 542,51.24 for patients without ulcer.Conclusion: The presence of ulcers and glycemic conditions had an effect on the direct costs; insulin use also affected the direct costs. The direct costs of diabetic ulcer were significantly higher than non-ulcer, and they were predominantly affected by insulin prescribing.
Willingness to Pay for Breast Cancer Screening: A Systematic Review Ramadhani, Anietta Indri; Kristina, Susi Ari; Trung, Vo Quang
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.94440

Abstract

Background: Women's breast cancer was identified as the primary contributor to global cancer cases. This condition puts a significant economic burden on both society and the healthcare system, with the highest expenses related to medical treatment costs.Objectives: The study aims to review the willingness to pay (WTP) for breast cancer screening and the factors influencing it.Methods: Four databases (Scopus, PubMed, ProQuest, and Google Scholar) were used to search related articles that mentioned the WTP for breast cancer screening. Preferred Reporting Items for Systematic Reviews (PRISMA) guideline was used to execute this systematic review study. Finally, 11 articles were included in this study. The quality of reviewed studies was assessed using a JBI cross-sectional study and a JBI quasi-experimental study.Results: The study found that the WTP value for breast cancer screening varied from $1 to $500 in Iran, Malaysia, Singapore, the US, and Canada. Most studies explained that willingness to pay and willingness to take breast cancer screening were affected by sociodemographic aspects such as family history of ovarian or breast cancer, income status, education status, age, and marital status.Conclusion: Governmental authorities should consider the implementation of a breast cancer screening program or explore cost-sharing mechanisms for breast screening, to mitigate the incidence of breast cancer.
Factor Influencing Willingness to Pay for Prediabetes Screening and Prevention Program: A Systematic Review Rochmanov, Janne; Kristina, Susi Ari; Yasin, Nanang Munif
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.95004

Abstract

Background: IDF, or The International Diabetes Federation predicts that by 2045, there will be 783 million adults (12,2%) with diabetes globally, up from 540 million (10,5%) in 2021 projects that by 2045, there will be 783 million adults (12,2%) with diabetes globally, up from 540 million (10,5%) in 2021. Research has shown that lifestyle modifications, such as changes in diet and exercise, can significantly reduce the chance that prediabetes patients will get diabetes.Objectives: The aim of this systematic review was to examine the factor influencing willingness to pay (WTP) for prediabetes screening and prevention programs.Methods: Between October and December 2023, relevant keywords were used to search Scopus, PubMed, Sage, and Web Science for articles published between 2006 and 2023. This provided the necessary information. The Quality assessment of the studies was assessed using JBI for Cross–Sectional studies.Results: Finally, a total of eight studies were selected for review. Over 90% of the participants were men, and most had experience as health workers. Overall, respondents accepted it well with a positive prevalence of high willingness to pay, namely more than 78.9%. The most frequently used method for measuring WTP was CVM (25%) and DCM (25%).Conclusion: Despite the fact that some people would prefer to pay more, the results demonstrated that WTP was comparatively high when screening tests and preventative were provided for free or at a reasonable cost. It is recommended to increase people's awareness and motivation for lay people with diabetes.
Exploring Technology Acceptance Models: A Systematic Review of Health Application Adoption in Asian Countries Damanik, Ferina Septiani; Widayanti, Anna Wahyuni; Wiedyaningsih, Chairun
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.96755

Abstract

Background: Health applications are a crucial technological advancement in healthcare, enhancing service quality and access to essential information. Despite this, challenges in implementation and user adaptation remain. Evaluating these applications is vital, and the Technology Acceptance Model (TAM) provides a dependable framework for assessing user acceptance and meeting its intended goals.Objectives: This review aims to explore the use of the TAM method for evaluating health applications adoption in Asia, focusing on ease of use, usefulness, user attitudes, and factors affecting technology acceptance.Methods: The method used is Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Articles were gathered using PubMed and ScienceDirect employing Boolean search terms. The search focuses on technology acceptance and health applications, combined with the names of Asian countries. Eligible studies must describe the technology acceptance model of a health application in Asia. Quality assessment is performed using JBI and data are systematically extracted and analyzed.Results: A total of 11 original articles meet the inclusion criteria from 2428 articles. TAM plays a pivotal role in understanding the adoption of healthcare technology in Asia. TAM original constructs are widely used, with some integrating additional factors. Continued integration and modification of TAM will enhance its utility in addressing evolving healthcare challenges, ultimately improving healthcare outcomes across diverse user settings. TAM's adaptability and integration with theories like PMT and SUS improve its relevance across various healthcare settings and user contexts.Conclusion: Future research should mitigate biases, employ longitudinal and comparative analyses, and integrate TAM with complementary theories to advance healthcare technology adoption.
Effectiveness and Safety Comparison of Clozapine-Haloperidol with Clozapine-Risperidon Regimen in Schizophrenia Inpatients at Prof. Dr. Soerojo Magelang Mental Hospital Mustikawati, Maria Sri Ayu; Budiman, Bambang Hastha Yoga Legowo; Ikawati, Zullies
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.96818

Abstract

Background: Schizophrenia treatment uses drugs from the antipsychotic group. Antipsychotics combination of clozapine-haloperidol and clozapine-risperidone are widely used in schizophrenia inpatients. Clozapine is often used in combination with haloperidol and risperidone (high-potency antipsychotic) to enhance the blockade of D2 receptors.Objectives: To compare the effectiveness and safety of the clozapine-haloperidol regimen with clozapine-risperidone used by schizophrenia inpatients.Methods: The research design was retrospective cohort observational. Data collection based on medical records of inpatients diagnosed with schizophrenia at Prof. Dr. Soerojo Magelang Mental Hospital in January 2021 - June 2023. The subjects were 142 people (71 people in both groups). Effectiveness was assessed by the difference in pre and post-PANSS-EC scores, as well as clinical improvement through the final PANSS-EC score. Meanwhile, safety was evaluated based on the incidence of drug side effects. The data was then analyzed statistically.Results: The average PANSS-EC score decrease was 10 ± 5.53 in the clozapine-haloperidol group and 11 ± 5.70 in clozapine-risperidone group. Nonetheless, there was no meaningful contrast between them in terms of PANSS-EC difference (p=0.326), or improvement in clinical condition by the final PANSS-EC score (p=0.111). Also, there was no meaningful distinction in the incidence of adverse drug events (p=0.422).  However, extrapyramidal syndrome, the most frequent side effect (18 out of 40 cases), had a significant difference with the clozapine-haloperidol group having the most cases (p=0.044).Conclusion: Both regimens are interchangeable in clinical practice. But clozapine-risperidone is better tolerated regarding extrapyramidal side effects.
Streamlining Oral Antidiabetic Prescribing Through Clinical Pathway Implementation Wardani, Susilo Ari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.98056

Abstract

Background: Diabetes mellitus (DM) is a disease that falls into the high-volume, high-risk, and high-cost categories. A concordance of oral anti-diabetic drug prescribing with the clinical pathway (Pedoman Praktik Klinis, PPK) will ensure drug availability for patients in the universal coverage era.Objectives: This study aimed to analyze the quantity and quality of antidiabetic drug use before and after PPK implementation, including concordance with the national formulary and PPK.Methods: This cross-sectional study analyzes oral antidiabetic drug use for inpatient DM (ICD-10 E11) at Sumberglagah Regional Hospital, Mojokerto, East Java Province, Indonesia. Data were collected retrospectively from medical records and the pharmacy database. Drug utilization was presented in Defined Daily Dose per 100 bed-days descriptively.Results: The quantity of inpatient DM drug use was 189.17 DDD/100 bed-days and 249.42 DDD/100 bed-days, before and after PPK implementation. The types of DM drugs that were included in the 90% DU category, before and after PPK implementation, were Insulin Aspart, Insulin Glargine, Glimepiride tablets, and Insulin Glulisine. The quality of DM drug use was 100% following the National Formulary 2022 and the PPK.Conclusion: The oral anti-diabetic drugs in the 90% drug cumulative have great attention in the procurement to raise the financial efficiency. The DDD/100 bed-days of anti-diabetic and the number of items of anti-diabetic drugs are increasing, therefore necessitates proactive strategies to manage potential cost escalation for payers, i.e., The Government of Republic Indonesia.
Cost-Effectiveness Analysis of Antibiotic Therapy for Community-Acquired Pneumonia at Mimika Regional Hospital, Central Papua Arifin, Bustanul; Sattu, Fidel Yoel Junovray; Saud, Anshar
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.98701

Abstract

Background: Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide, affecting the lower respiratory tract. It is caused by diverse pathogens, including bacteria, viruses, fungi, and chemical exposures. Antibiotics, such as ceftriaxone, are widely used for treatment. However, the high economic burden associated with CAP management necessitates a cost-effectiveness analysis to optimize treatment strategies.Objectives: This study aimed to evaluate the cost-effectiveness of three antibiotic regimens—co-amoxiclav, meropenem + levofloxacin, and ceftriaxone—for CAP inpatients at Mimika Hospital, Indonesia, to identify the most efficient therapeutic option.Methods: A retrospective, cross-sectional observational study was conducted using medical records of CAP patients admitted to Mimika Hospital between January and December 2021. Inclusion criteria were patients aged ≥18 years who received a single antibiotic regimen. Treatment effectiveness was assessed based on hospitalization duration (≤3 days) and physician-reported recovery. Cost-effectiveness was evaluated using the Average Cost-Effectiveness Ratio (ACER).Results: A total of 120 pneumonia inpatients were analyzed, predominantly male (60%) and aged 26–45 years (34%). The most frequently administered antibiotic was ceftriaxone (51%), followed by co-amoxiclav (29%) and meropenem + levofloxacin (20%). Co-amoxiclav demonstrated the highest clinical effectiveness (88.57%) and the lowest median total cost (IDR 2,696,114), resulting in the lowest ACER value (IDR 2,696,114/effectiveness unit) and a dominant ICER status. In contrast, meropenem + levofloxacin showed moderate effectiveness (75%) at the highest cost (IDR 3,088,961), with an ICER of IDR 18,538.64. Ceftriaxone had the lowest effectiveness (65.57%) and the highest ACER (IDR 44.443,22), indicating poor cost-efficiency. These findings position co-amoxiclav as the most cost-effective regimen across both clinical and economic parameters.Conclusion: Co-amoxiclav is the most cost-effective antibiotic regimen for CAP inpatients at Mimika Hospital, offering optimal therapeutic outcomes at a lower cost. These findings support its recommendation as the first-line treatment for CAP in similar healthcare settings
Health Literacy of Individuals with Visual Impairments in Yogyakarta Province, Indonesia Widyakusuma, Niken Nur; Ekasari, Marlita Putri; Wiedyaningsih, Chairun
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.101362

Abstract

Background: Individuals with visual impairments tend to have low health outcomes. Exploring health literacy among this group can provide a basis for designing effective strategies for healthcare services that assist this special population.Objectives: This study aimed to determine the health literacy level of individuals with visual impairments.Methods: A cross-sectional study was employed in this study. We administered a survey using the Health Literacy Scale European Union Q16 (HLS-EU-Q16) Indonesian version questionnaire to individuals with visual impairments in Yogyakarta. Members of two Non-Government Organisations (NGOs), namely Ikatan Tunanetra Muslim Indonesia/Indonesian Muslim Blind association (ITMI) and Persatuan Tuna Netra Indonesia/Indonesian Blind Association (Pertuni) were invited as respondents using a purposive sampling method. Data was collected during the NGOs regular meetings in August and September 2019, which took place in some members’ houses or public places throughout Yogyakarta province.Results: A total of 95 eligible respondents who consented to join the study had a health literacy index of 31.29 ± 8.91, classified as problematic, with an index range between 3.13 and 50.00 (inadequate to excellent).Conclusion: Our findings revealed that individuals with visual impairments have problematic health literacy and face multiple determinants to improve their health literacy. This condition requires pharmacists and other health professionals to be aware of it and to develop an appropriate strategy to deal with it comprehensively.
The Relationship Between Pharmacist Workload and the Clinical Pharmacy Services Quality of Kulon Progo Regency Dewi, Dina Nurlita; Annisaa', Eva; Dianingati, Ragil Setia
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.93714

Abstract

Background: Clinical pharmacy service activities are the decisive roles of pharmacists in ensuring patient safety and quality of life, so there is a need for quality control in their implementation. However, several studies classify the clinical pharmacy services quality at primary health centers as needing improvement. On the other hand, pharmacists at primary health centers in Kulon Progo are overburdened, exceeding the standard rasio.Objectives: This study aims to determine the relationship between the pharmacists workload and the clinical pharmacy services quality.Methods: This study is an analytic observational study with a retrospective and prospective approach. The research participants are five pharmacists from the three sample primary health centers. The pharmacist's workload was measured using the daily log workload form, while the clinical pharmacy services quality was measured using ten indicators of clinical pharmacy service quality. The pharmacist workload is classified into heavy (>80%), moderate (60-80%), or light (<60%) categories. Meanwhile, the quality of clinical pharmacy services is classified into proper (>75%), fair (56-75%), or poor (<56%). The relationship between pharmacist workload and clinical pharmacy service quality was analyzed using the Somers correlation test.Results: The pharmacists’ workload at Sentolo I, Temon I, and Galur II primary health centers, respectively, is heavy (94.05%), heavy (84.55%), and moderate (79.91%). The clinical pharmacy services quality at Sentolo I, Temon I, and Galur II primary health centers, respectively, were fair (56.57%), fair (69.21%), and proper (79.05%). Somers test results show a significant relationship (p=0.014) between the pharmacists’ workload and the clinical pharmacy services quality. The correlation coefficient obtained is -1,000.Conclusion: There is a significant relationship between pharmacist workload and clinical pharmacy service quality.

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