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INDONESIA
BIOEDUSCIENCE
Published by Universitas Muhammadiyah Prof. Dr. Hamka
ISSN : 2614154X     EISSN : 26141558     DOI : -
Core Subject : Science, Education, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education
BIOEDUSCIENCE is an open access journal that publishes research in the field of Biology and Biosain Education such as: Applied and implemented in education and learning, Botany, Zoology, Microbiology, Ecology, Biotechnology, Molecular Biology, Genetics, Bioinformatics, Cell and Developmental Biology, Biodiversity and Bioconservation. BIOEDUSCIENCE is published by Biology Education Study Program, Universitas Muhammadiyah Prof. Dr. Hamka, Indonesia regularly in June and December. ISSN : 2614-1558; P-ISSN : 2614-154X.
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Articles 544 Documents
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Kajian Kondisi Keberadaan Anoa Dataran Rendah dengan Anoa Pegunungan di Pulau Sulawesi Ditinjau dari Jenis Pakannya Daffa Azalia; Intan Rachmawati; Ade Suryanda
BIOEDUSCIENCE Vol 6 No 2 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/628017

Abstract

Background: Anoa is an endemic animal on Sulawesi island which is threatened with extinction, both lowland anoa (Bubalus depressicornis) and mountain anoa (Bubalus quarlesi) which share the status of Endangered. The aim of this study is to determine the condition of lowland anoa and mountain anoa on the Sulawesi island in terms of the type of feed. Methods: This research was accomplished using literature review techniques. Results: The outcome of this study showed a represent that lowland anoa in terms of feed type has an endangered status, as well as mountain anoa in terms of feed type, which is endangered. The status of the existence of lowland anoa and mountain anoa, both from the type of feed and the IUCN conservation organization, is equally threatened with extinction. The same condition and conservation status is obtained by the result because the two different anoas that lives in different habitats are able to adjust their own feed according to where the animals are. Conclusions: Although it has no bearing on anoa condition and conservation status, it is expected that the national park and captivity of anoa on Sulawesi Island can better sort food for lowland anoa and mountain anoa to support their physiological functions for their existence.
Pemanfaatan Pewarna Alami Kain Tenun Futus Sebagai Alternatif Pewarna Preparat Jaringan Tumbuhan Yolanda Getrudis Naisumu; Emilia Juliyanti Bria; Welli Herlince Kasse
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/618079

Abstract

Background: Natural plant dyes can replace synthetic dyes to reduce the negative effects caused. This study aims to determine the types of color-producing plants, the process of using natural dyes as dyes for plant tissue preparations and the percentage of quality and feasibility of plant tissue preparations. Methods: experiments were carried out in the application of natural plant dyes on plant tissue preparations. Data analysis was carried out to calculate the percentage of quality and feasibility of the preparations. Results: there were eight plant species from four families namely Fabaceae, Zingiberaceae, Maliaceae, and Lamiaceae. The process of processing plant parts into natural dyes is by soaking, boiling, pounding, grated and applied to preparations of corn and spinach plants. The use of natural dyes on corn and spinach preparations with a percentage of preparation quality ranging from 33.33% - 75.00% and said to be poor to good, while the percentage of feasibility of preparations ranged from 67.08% - 87.50% and was said to be feasible to very suitable for use in the observation of plant cells and tissues. Conclusions: Natural dyes from futus fabrics can replace synthetic dyes in dyeing plant tissue preparations.
Anti-PD-L1 Therapy as a Solution for Non-Melanoma Skin Cancer Basal Cell Carcinoma Rahul Simon Situmeang; Gim Mi Kyong; Rosiva Betaria Purba; Wahyu Irawati
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/618095

Abstract

Skin cancer is a disease that can cause the loss of the ability to regenerate and protect the skin normally. The types of skin cancer that are known are melanoma and non-melanoma skin cancer. Non-melanoma Basal cell carcinoma is a malignant neoplasm originating from non-keratinizing cells in the basal layer of the skin's epidermis. The treatment itself is carried out through the application of immunotherapy, namely the use of drug therapy Programmed Death Ligand 1 (PD-L1). This study aims to see the effectiveness of PD-L1 Therapy as a treatment for basal cell carcinoma. The focus of the study of the article is the integument system, skin cancer, non-melanoma basal cell carcinoma, and the effect of anti-PD-L1 use. The research method used is a literature review from various sources. Skin cancer Basal cell carcinoma attacks the basal cells of the epidermis, causing disruption. Attacks slowly, but when ignored will spread wider and more severe. Through PD-L1 therapy by binding to PD-1 receptors on immune cells, it causes the activation of T lymphocytes as anti-cancer cells in the body that suppress growth while actively controlling tumor cells. Through the use of PD-L1 therapy in treating cancer that attacks basal cells, it will suppress growth, destroy and shrink cancer cells, and increase the body's immunity against cancer cells.
Gastropoda Diversity in Polyculture Agricultural Ecosystem of Nansean Village, Insana District, North Central Timor Regency- East Nusa Tenggara Province (NTT) Blasius Atini; Aloysius Rusae
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/618539

Abstract

Background: The research was carried out in the polyculture area of Nansean Village, North Central Timor Regency. This study aims to determine the diversity of Gastropoda species and also to determine the influence of environmental factors on the Gastropoda life in the polyculture agricultural ecosystem of Nansean Village. Methods: The method used in this research is the quadratic method by placing plots along the transect line. The data analysis technique for Gastropoda diversity was using the Shannon-Winner diversity formula. Results: From the results of the study, it was found that 6 types of Gastropoda namely Achatina fulica with a diversity index (H') of (3.51) were classified as high. Laevicaulis alte Bowd with a diversity index (H') of (1,15) was classified as moderate. Felicaulis sp with a diversity index (H') of (1,25) was classified as moderate, Bradybaena similaris Frussac with a diversity index (H') of (1,26) was classified as moderate. Achatina variegata Bowd with diversity index (H') of (0.92) is low. Doraceras leave sp with a diversity index (H') of (0.87) is low. Species diversity shows the pattern of adaptation to ecosystem conditions is quite good, and vice versa if the type of Gastropoda is low. Conclusions: the environment has a role in diversity variations in Nansean Village, Insana District, and North Central Timor Regency.
Optimasi Volume Kit Da An Gene Untuk Deteksi SARS-CoV-2 dengan Real Time RT-PCR Seprianto Seprianto; Muhammad Arreza; Titta Novianti; Febriana Dwi Wahyuni; Oktaviani Naulita Turnip; Roaslein Putri; Henny Saraswati
BIOEDUSCIENCE Vol 6 No 2 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/628595

Abstract

Background: SARS-CoV-2 is a new type of coronavirus of the genus Betacoronavirus and the family Coronaviridae that causes a respiratory disease called COVID-19. The virus has a sheath and genetic material in the form of single-chain RNA. The genome structure of this virus is divided into two types, namely genes that encode non-structural proteins consisting of the ORF1a / ORF1b gene and genes that encode structural proteins consisting of spike glycoprotein (S), envelope (E), membrane glycoprotein (M), and nucleocapsid protein (N). Methods: The method of detecting SARS-CoV-2 with real time RT-PCR is the most recommended method because it has high specificity and accuracy. The specificity of a method is necessary to be able to specifically recognize the pathogen that causes the disease. Real time RT-PCR requires sampling with a swab on the oropharynx or nasopharynx to be examined in the laboratory which later the presence of viral RNA becomes a molecule that is assessed for diagnosis results. In this study, volume optimization was carried out on the Da An Gene kit used for the detection of SARS-CoV-2 with Reverse Transcription Polymerase Chain Reaction (Real time RT-PCR) with the aim of saving the use of reagents from available kits but with amplification results remaining optimal and accurate. Results: There were three SARS-CoV-2 RNA samples used consisting of N62, N63, and N79 samples and three types of total volume used were 20 μl, 15 μl, and 10 μl. The results of this study showed that the three positive samples contained SARS-CoV-2 with a Cq value of < 40. Conclusion: A volume of 20 μl is the optimal volume, which is more efficient than the manufacturer's recommended volume of 25 ul.
Konsentrasi Logam Berat Cd, Hg, Pb pada Produk Pangan Olahan Berbahan Dasar Pterygoplichthys pardalis (Castelnau, 1855) asal Sungai Ciliwung Wilayah Jakarta Dewi Elfidasari; Haninah Haninah; Handhini Dwi Putri; Irawan Sugoro
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/618708

Abstract

Backgrounds: Heavy metal that pollutes the river area affects living organisms which reside in it. Contamination of heavy metal in Ciliwung River leads to the presence of heavy metal elements (Cd, Hg, and Pb) inside the body of the plecos (Pterygoplichtys Pardalis) which inhabits that area. Hence, the utilization of plecos flesh and bones as a raw material in processed food products (e.g. shredded fish, shumai, and fish flour) might be harmful for human. Accumulated load of heavy metal in human's body would likely trigger health problems. Insufficient data on heavy metal concentration in Ciliwung River plecos-based food products underlies this research, with the aim to calculate the concentration of heavy metal Cd, Hg, and Pb on the previously mentioned plecos-based shredded fish, shumai, and flour. Methods: Heavy metal Cd, Hg, and Pb concentration analysis using X-Ray Fluoresence (XRF) methods conducted on PAIR Batan. Results: Value of Cd on shredded fish <0.5 mg/kg, shumai 0,7 mg/kg, head+tailbone and body skeleton flour <0.3 mg/kg. Value of Hg on shredded fish and shumai <0.7 mg/kg, head+tailbone flour 0.3 mg/kg, body skeleton flour 0.4 mg/kg. Value of Pb on shredded fish 1.3 mg/kg, shumai 0.8 mg/kg, head+tailbone flour 2.3 mg/kg, body skeleton flour 1.6 mg/kg. Conclusions: Heavy metal concentration on Ciliwung River plecos-based processed food products (shredded fish, shumai, and flour) has exceed maximum limit of Cd, Hg, and Pb determined by SNI, BPOM, and FAO.
Pengembangan Booklet Digital Materi Keanekaragaman Hayati Kelas X Kencana Hastin Prameswati; Much. Fuad Saifuddin
BIOEDUSCIENCE Vol 6 No 3 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/628760

Abstract

Background: Distance learning requires learning media to help students understand the material. Digital booklets are an alternative to teaching biodiversity through visualization. This study aimed to determine the feasibility of digital booklets for class X biodiversity materials. Methods: This Research and Development use the ADDIE model. The product is validated by expert validators, material experts, and teachers. Product trials on students were divided into two groups, namely small groups (10 students) and large groups (30 students). Results:  The results of the product assessment meet the very feasible category with scores of 91.67% (media experts), 61.25% (material experts), and 81.25% (teachers). The small group test on students obtained a percentage of 96%, and the big group test with a percentage of 95.33%. Conclusions: The digital booklet learning media product is suitable for class X biodiversity learning.
Identifikasi Protein Plasmodium falciparum yang Tidak Berkarakter Melalui Analisis In-silico Vianney Widjaja; Albert Lim; Benedicta Aini; Gabrielle Audrey Gandasasmita; Jeremie Theddy Darmawan; Arli Aditya Parikesit
BIOEDUSCIENCE Vol 6 No 2 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/628770

Abstract

Background: Numerous types of research on malaria were done over a long period of time but there are still some unknowns. However, it is globally known that malaria is caused by the Plasmodium parasite, mainly and most lethally by Plasmodium falciparum. The purpose of this research is to understand the structure and function of three uncharacterized P. falciparum proteins (PF3D7_1468000, PF3D7_1147400, PF3D7_1351100) using bioinformatic methods in hopes to learn more about malaria. Methods: The three uncharacterized P. falciparum proteins were inserted into Phyre2 for knowing the protein homology, InterPro, and SUPERFAMILY hidden Markov models for understanding the domain annotation, scanprosite for knowing the post-translational modification, Ramachandran plot for protein validation, and Yasara for visualizing the protein. Results: According to the Phyre2 results, the third protein showed the highest confidence and coverage level of 100%, followed by the second protein, and the lowest was the first protein. Interpro and SUPERFAMILY results identified the first protein as WD40 repeat superfamily, the second protein as Cytochrome C subunit II-like, and the third protein as CXXC motif. Scanprosite revealed all sequences possessing protein domains in which the first protein has three protein domains, the second protein has one protein domain, and the third protein has two protein domains. According to the Ramachandran plot, the first and second protein generally has an α-helix structure while the third protein has an overall β-sheet structure, which differs to some extent from the protein structure visualization. The three protein visualizations exhibited secondary structures and more than 50 amino acid residues for each protein. Conclusion: This research concluded that the second and third uncharacterized proteins (PF3D7_1147400, PF3D7_1351100) could be promising antimalarial drug targets leading to the P. falciparum parasite death.
Pengaruh Model Pembelajaran Berbasis Masalah dengan Bantuan Komik Digital terhadap Kemampuan Literasi Ilmiah Siswa Rini Rita T. Marpaung; Berti Yolida; Arrum Ardila Faros; Median Agus Priadi; Dina Maulina; Ismi Rakhmawati; Nadya Meriza; Laily Fatimatuzzahra; Yosi Fatmawati
BIOEDUSCIENCE Vol 6 No 3 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/638790

Abstract

Background: The low scientific literacy of students is caused by the selection of models and learning media that are less varied. This study aims to analyze the effect of the PBL model with digital comics on students’ scientific literacy on environmental pollution material. Methods: This type of research is a quasi-experimental nonequivalent control group design. The research sample used classes, namely class VII A and VII F, with 55 students selected using a purposive sampling technique. Results: The experimental class's average N-Gain of scientific literacy ability (0.42 ± 0.171) is moderate, while the control class (0.26 ± 0.17) is low. Conclusions: The results of this study indicate that Sig. (2-tailed) 0.001 < 0.0, meaning that the PBL model using digital comics model cs influences students' scientific literacy skills.
Efektivitas e-LKPD Berbasis keterampilan Proses Sains Pada materi Semester I Kelas XI SMA/MA Suhardi Aldi; Adnan Adnan; Ismail Ismail
BIOEDUSCIENCE Vol 6 No 3 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/638846

Abstract

Background: Test the effectiveness of electronic student worksheets (e-LKPD). The hope of this research is to test the effectiveness of e-LKPD based on science process skills. The type of this research is research and development which refers to the type of ADDIE development (Analysis, Design, Development, Implementation, and Evaluation). The resulting product is an e-LKPD based on science process skills (KPS), which is carried out effectively by 28 students. The instrument used is a multiple choice test. The instrument that has been developed is used for data collection. The resulting data is then analyzed quantitatively. Based on the results of the study, it is illustrated that the level of effectiveness of the KPS-based e-LKPD in terms of student learning outcomes is 0.7 which is in the effective category with a moderate level. So that the PPP-based e-LKPD is effective at a moderate level.

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