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Herb-Medicine Journal
Published by Universitas Muhammadiyah Purwokerto
ISSN : -     EISSN : 2620567X     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Herb-Medicine Journal (HMJ) merupakan Terbitan Berkala Ilmiah Herbal, Kedokteran, dan Kesehatan diterbitkan oleh Fakultas Kedokteran Universitas Muhammadiyah Purwokerto dengan frekuensi terbit 2 (dua) kali dalam setahun yaitu di bulan April dan Oktober. Jurnal ini merupakan media komunikasi ilmiah bagi siapapun yang tertarik menekuni bidang herbal baik dalam proses pendidikan, penelitian, maupun pengabdian kepada masyarakat yang dihubungkan dengan bidang kedokteran maupun kesehatan secara luas. Secara terbuka, redaksi menerima kontribusi artikel ilmiah tentang herbal, kedokteran, dan kesehatan dari pihak manapun yang ingin berpartisipasi dalam perkembangan dunia herbal, kedokteran, dan kesehatan.
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Articles 7 Documents
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Search results for , issue "Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021" : 7 Documents clear
Hubungan Antara Usia Ibu Hamil dengan Preeklampsia Tipe Lambat di Rumah Sakit PKU Muhammadiyah Surabaya Ali Mustofa; Ninuk Dwi Ariningtyas; Kartika Prahasanti; Muhammad Anas
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i4.9737

Abstract

Preeclampsia is one of the most common complications in pregnancy that can lead to various complications such assevere illness, long-term disability, andmaternal, fetal, and neonatal mortality. The prevalence of preeclampsia, 30%-40% can cause maternal mortality, and 30%-50% can lead to perinatal mortality. Maternal age is one of the riskfactors for late-onset preeclampsia. Maternal age is grouped into two categories; extreme age (<20 years and> 35 years)and reproductive age (21-35 years). This studyaims to determine the relationship between maternal age and late-onsetpreeclampsia at PKU Muhammadiyah Surabaya Hospital from January to June 2020. The research method used isobservational analytic with case control design. The samples involved were pregnant women visiting PKUMuhammadiyah Surabaya Hospital from January to June 2020. The data were analyzed using a statistical test ofcontingency coefficient correlation. The results showed that respondents who experienced late-onset preeclampsia inthe extreme age group (<20 years and> 35 years) were 37 respondents (100%) and in reproductive age (21-35 years)were 28 respondents (80%), the respondent who did not experience late-onset preeclampsia in extreme ages (<20 yearsand> 35 years) was 0 respondents(0%) and in reproductive age (21-35 years) were 7 respondents (20%). The resultsof the statistical test for the contingency coefficient correlation showed a p-value of 0.004 below (≤0.05). All thingsconsidered, there was a significant relationship between maternal age and late-onset preeclampsia at the PKUMuhammadiyah Surabaya Hospital from January to June 2020.
Pengaruh Pemberian Ekstrak Etanol Daun Kemangi (Ocimum basilicum L.) Terhadap Cedera Tubulus Ginjal Farah Akhwanis Syifa; Rizka Adi Nugraha Putra; Andi Muhammad Maulana; Susiyadi Susiyadi
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i4.4555

Abstract

According to the European Food Safety Authority (EFSA),the allowed level of Monosodium glutamate (MSG)consumption is 30 mg / kgbw per day. Several studies show that long-term MSG is toxic to the kidneys bycausingoxidative stress and decreasing thekidney function.This study was based on the potential for impaired kidneyfunction and structure caused by excessive consumption of MSG and basil leaves (Ocimum basilicum L.) asantioxidant plants with flavonoid content. To find out the effect of basil (Ocimum basilicum L.) leaves’ ethanolextract dose 175 mg / kgbw, 350 mg / kgbw and 700 mg / kgbw against kidney tubular injury on white rats WistarStrain induced by MSG.This study was a quasi-experimental study with a randomized post-test only controlledgroup design. The number of samples was 25 ABM, divided into five groups, the positive control group (K+), thenegative control group (K-) and the treatment group (K1,K2 and K3).In the group given basil leaves ethanol extractdoses of 175, 350 and 700 mg / kgbw, there was a decrease in tubular injury in the kidney of the white rat (Rattusnorvegicus) Wistar strain induced by MSG 1.6 g/day orally. The optimal dose in this study was 700 mg / kgbw. Teststatistics indicated significant differences in all five groups (p < 0.05).The administration of ethanol extract of basilleaves (Ocimum basilicumL.) was able to prevent tubular injury in the kidney of the white rat (Rattus norvegicus)Wistar strain induced by MSG. Kadar konsumsi MSG yang diperbolehkan menurut Europian Food Safety Authority (EFSA) yaitu 30 mg/kgBB per hari. Beberapa studi pada hewan coba menunjukkan bahwa pemberian MSG jangka panjang bersifat toksik padaginjal dengan menyebabkan stress oksidatif dan menurunkan fungsi ginjal. Penggunaan tanaman yang mengandungantioksidan dapat meningkatkan mekanisme dalam tubuh untuk mencegah stres oksidatif. Penelitian ini didasarkanoleh potensi terjadinya gangguan fungsi dan struktur ginjal akibat stres oksidatif yang disebabkan oleh konsumsiMSG berlebih serta daun kemangi (Ocimum basilicum L.) sebagai tanaman antioksidan dengan kandunganflavonoid.Mengetahui pengaruh pemberian ekstrak etanol daun kemangi (Ocimum basilicum L.) dosis 175,350 dan700 mg/kgBB terhadap cedera tubulus pada BBT ginjal tikus putih (Rattus norvegicus) galur Wistar  yang diinduksiMSG.Penelitian ini merupakan jenis penelitian quasi-experimental dengan rancangan randomized post test onlycontrolled group. Jumlah sampel sebanyak 25 BBT, terbagi menjadi lima kelompok, yaitu kontrol positif (K+),kontrol negatif (K-) dan kelompok perlakuan ekstrak daun kemangi (K1, K2 dan K3).Pada kelompok pemberianekstrak etanol daun kemangi terjadi penurunan cedera tubulus pada ginjal tikus putih (Rattus norvegicus) galur Wistar  yang diinduksi MSG 1,6 g/hari secara oral.  Dosis optimal ekstrak etanol daun kemangi padapenelitian iniyaitu 700 mg/kgBB. Uji statistik menuunjukkan perbedaan yang signifikan pada kelima kelompok (p<0,05). Pemberian ekstrak etanol daun kemangi (Ocimum basilicum L.) dapat mencegah terjadinya cedera tubulus padaginjal tikus putih (Rattus norvegicus) galur Wistar  yang diinduksi MSG.
Hubungan Antara Status Gizi Dan Kebiasaan Berolahraga Dengan Nilai Volume Oksigen Maksimal (VO2 Max) Pada Siswa Laki - Laki SMP Negeri Di Temanggung Selama Pandemi Covid-19 Irvan Dwi Cahyono; Tri Agustina; Sri Wahyu Basuki; Budi Hernawan
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i4.10218

Abstract

The negative impacts of the Covid-19 pandemic include anxiety, stress, reduced appetite, boredom, and physical fitnessproblems. These conditions certainly affect the nutritional status and also the cardiorespiratory fitness of a person. InIndonesia, at least 15 out of 1000 people, or around 2,784,064 individuals suffer from heart disease. In Central JavaProvince, 0.61% of them are children aged 5-14 years old (Riskesdas, 2018). The VO2 Max value is a method formeasuring cardio respiration that can be used to determine which children are at risk of suffering from cardiovasculardisease. The VO2 Max value is influenced by several factors, including nutritional status and exercise habits. Thisstudy aimed to find out the correlation between nutritional status and exercise habits and the value of maximum oxygenvolume (VO2 Max) in male students at SMP Negeri in Temanggung during the Covid-19 pandemic. This was adescriptive-analytic study with across-sectional design. The sampling was done using the purposive sampling methodon 57 samples at SMP Negeri 1 Kaloran. It used Chi-square test for nutritional status variable with p value = 0.000 andexercise habits with p value = 0.001. The logistic regression test was used for each p-value with the nutritional statusOR value of 6.640 and the exercise habit OR value of 4.807 and with R Square value of 0.38 or 38%. There was acorrelation between nutritional status and exercise habits and the value of maximum oxygen volume (VO2 Max) inmale students at SMP Negeri in Temanggung during the Covid-19 pandemic.
Formulasi dan Uji Stabilitas Sediaan Suspensi Ekstrak Rimpang Zingiber zerumbet Shafa Shavira; Angel Dineta Margaretta; Aprilia Dwi Sandra; Raya Uli Sitorus; Fatmaria Fatmaria
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i4.11628

Abstract

Zingiber zerumbet (L) Smith rhizome has been used traditionally as an herbal medicine in Indonesia. Isolated extracts and metabolites of Z. zerumbet have shown anti-inflammatory, antioxidant, antidiabetic, anticancer, antimicrobial, analgesic and antiviral activity. The form of suspension is carried out to facilitate the utilization of the main bioactive content, zerumbone, which is difficult to dissolve in water. The formulation of suspension is based on variations in the concentration of Z. zerumbet extract, which is 2.5% (formulation 1), 5% (formulation 2), and 10% (formulation 3). To determine the physical stability, the evaluation is carried out, namely: organoleptic test, density, viscosity, redispersibility and pH. The results showed all three formulations did not provide organoleptic changes for 30 days, >1 g/cm3 density, good redispersibility, and pH of 6. The viscosity of each formulation is quite varied i.e., 3.74 cp; 4,27 cp; and 11.8 cp. Formulation 3 is determined as the best formulation based on its viscosity which is closest to the standard range of good suspension viscosity according to the SNI.
Perbandingan Uji Aktivitas Antibakteri Filtrat Aquadest Umbi Bawang Suna (Allium schoenoprasum L.) Terhadap Pertumbuhan Streptococcus pneumoniae Dan Escherichia coli Dengan Metode Difusi Cakram Kirby-Bauer Bella Chrysthya Utamy; Ni Nyoman Sri Yuliani; Dewi Klarita Furtuna
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i4.8812

Abstract

Infectious diseases are one of the most frequent diseases of major health problems, caused by bacteria are still beinga health problem in developing countries as well as in developed countries. One of the mostly occurred respiratorytract infection is pneumonia, this caused by Gram-positive bacteria Streptococcus pneumoniae. Gastrointestinaldiseases that are often caused by gram-negative bacterial infections Escherichia coli. Local plant which can be foundin Central Kalimantan are Suna onion (Allium schoenoprasum L.). Suna onion (Allium schoenoprasum L.).Researchpurposes. Research was conducted to determine the influence of the Suna’s bulb (Allium schoenoprasum L.) filtratedby aquadest with a simple filtration technique on the growth of Streptococcus pneumoniae and Escherichia usingKirby-Bauer Disk Diffusion method. Method. This type of research is true experimental design research. The designused in this study was post test-only control group design. This research uses 7 treatment groups, with concentrationsof 100%, 75%, 50%, 25%, 12.5%. Aquadest as a negative control, Erytromycin and Cifrofloxacin as positivecontrols. The method used for testing the antibacterial activity are Kirby-BaueDisk Diffusionmethod.The resultsfound that the aquadest tuber extract of onion cannot inhibit the growth of Streptococcus pneumoniae andEscherichia coli. Conclusion. Aquadest filtrate of onion tubers (Allium schoenprasum L.) cannot inhibit the growthof Streptococcus pneumoniae and Escherichia coli
The Effect Of Family Support And Education On The Level Of Anxiety Of Pulmonary TB Patients In Community Lung Health Center (BKPM) Purwokerto Alifia Putri Karomah Budijarto; Mustika Ratnaningsih Purbowati; Refni Riyanto; Dyah Retnani Basuki
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i4.9579

Abstract

Pulmonary tuberculosis is a disease with a long duration of treatment and involves wide types of drugs which couldcause various adverse andharmful effects, then further could cause the risk of emotional changes such as anxiety. Therole of family support and education in reducing mortality, the escalating incidence rate of pulmonary TB in CentralJava Province, the unachieved target of successful TB treatment and also high rates of anxiety in TB patient, affirmthe necessity to conduct this research.To determine the effect of family support and education on the anxiety levelsamong pulmonary TB patients in BKPMPurwokerto.The type of this research is a quantitative study using a cross-sectional design. This research was conducted at the Purwokerto Community Lung Health Center with Spearman testas the hypothesis test used in the research.The analysis result shows the influence of family support on anxiety levelsobtained a p value <0.05 meanwhile  the influence of education on anxiety levels acquired a p value> 0.05.Familysupport could affect significantly while education could not significantly affect the anxiety levels in pulmonary TBpatients at BKPM Purwokerto
Identifikasi Telur Soil Transmitted Helminths Pada Caisim (Brassica chinensis) di Pasar Patikraja Kabupaten Banyumas Nurul Qomariyah; Dita Pratiwi Kusuma Wardani; Retno Sulistiyowati
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i4.10448

Abstract

Caisim (Brassica chinensis) is one of the vegetables that has many benefits such as protein, carbohydrates, fat and plays an important role in meeting food needs, and is good for health. Caisim is well adapted to high temperatures and the price is relatively stable and easy to cultivate. The purpose of this study was to determine the presence of Soil-Transmitted Helminths eggs in caisim (B. chinensis). The research was conducted in a descriptive observational. The research was conducted in July-August 2020 at Parasitology and Microbiology Laboratory, Faculty of Medicine, Universitas Muhammadiyah Purwokerto. Identification of Soil-Transmitted Helminths eggs from 20 caisim as the samples used NaCl flotation method and were analyzed by using a univariate test with tabulated frequency distribution. The results showed that no Soil-Transmitted Helminths eggs were found in caisim (B. chinensis).   Caisim (Brassica chinensis) merupakan sayuran yang mempunyai banyak kandungan manfaat seperti protein,karbohidrat, lemak dan berperan penting untuk memenuhi kebutuhan pangan serta baik untuk kesehatan. Caisimmampu beradaptasi dengan baik terhadap suhu tinggi serta harga relatif stabil dan mudah diusahakan. Tujuanpenelitian ini untuk mengetahui adanya telur Soil Transmitted Helminths terdapat pada caisim (B. chinensis).Penelitian dilakukan secara observasional deskriptif. Penelitian dilakukan pada bulan Juli-Agustus 2020 diLaboratorium Parasitologi Fakultas Kedokteran Universitas Muhammadiyah Purwokwerto. Identifikasi telur SoilTransmitted Helminthsdari 20 sampel caisim dengan metode Flotasi NaCl. dianalisis dengan uji univariat dengandistribusi tabulasi frekuensi. Hasil penelitian menunjukan tidak ditemukan telur Soil Transmitted Helminths padacaisim (B. chinensis)

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