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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
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Articles 12 Documents
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Search results for , issue "Vol. 8 No. 4 (2023)" : 12 Documents clear
Convalescent Plasma Treatment for Moderate to Critical Ill COVID-19 Patients – A Safe but Futile Treatment: A Non-Randomized Comparative Study Aphridasari, Jatu; Soetjahjo, Bintang; Joko, Agus; Sidharta, Rina; Harsini, Harsini; Arifin, Arifin; Permana, Septian Adi; Saraswati, Kunti; Adhiputri, Artrien; Marwanta, Sri; Laqif, Abdurahman; Danuaji, Rivan
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.620

Abstract

Background: In a number of cases of viral infection, convalescent plasma therapy has been effective. Reportedly, the use of convalescent plasma as a therapy for COVID-19 patients with severe and life-threatening disorders is beneficial at this time. This study aims to assess the effectiveness and safety of convalescent plasma transfusions in hospitalized COVID-19 patients. Subjects and Method: This was a clinical trial employing a non-randomized comparative study. A historical control group (21 samples) and convalescent plasma transfusions (21 samples) was selected consecutively from hospitalized COVID-19 patients between May 6th, 2020, and May 6th, 2021 at Dr. Moewardi General Hospital. We assessed and quantified viral clearance in the laboratory. Statistical analysis is performed in SPSS version 20.0. Results: Plasma was taken from fifteen convalescent donors. In the plasma convalescent treatment group, there was a statistically significant difference between outcome and severity degree (p = 0.005). In addition, there was a substantial discrepancy between the result group and the control group (p 0.005). Significant differences in post-treatment NLR between the control and treatment groups (p 0.005). In addition, there were statistically significant differences between the control and treatment groups in post-treatment hsCRP levels (p 0.005). In addition, there were statistically significant differences (p 0.005) between all groups' inflammatory markers and outcomes. Conclusion: Using convalescent plasma to treat patients with COVID-19 is a rather safe practice. Our analysis demonstrated that the administration of convalescent plasma did not enhance survival or clinical outcomes for COVID-19 patients with moderate to severe disease. Keywords: COVID-19, convalescent therapy, critical ill
Re-Infection of COVID-19 at Dr. Moewardi General Hospital, Surakarta, from March 2020 to June 2021 Aphridasari, Jatu
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.621

Abstract

Background: COVID-19 reinfection has been identified and is being studied. Several risk factors, including being a health worker and having A blood type, are linked to reinfection, and comorbidities such as hypertension, obesity, diabetes, and asthma influence the disease's severity. To identify mutational variations associated with viral virulence and spread, genetic studies are required. The purpose of this study is to determine the prevalence of SARS-CoV-2 reinfection, as well as patient characteristics and risk factors related to SARS-CoV-2 reinfection. Subjects and Method: This is a retrospective cohort study using data from the medical records of patients with COVID-19 reinfection treated at the Dr. Moewardi General Hospital (RSDM) Surakarta from March 2020 to June 2021. A sample was collected from 19 men and 20 women. The degree of COVID-19 infection is the dependent variable. Gender, occupation, comorbidities, and immunization history were the independent variables. The entire sampling method was employed in this investiga¬tion (consecutive sampling). Data is handled in Microsoft Excel 2010, and statistical analysis is performed in SPSS version 20.0. Results: COVID-19 re-infection is equally likely in men and women. The average patient age was 42 years, with patients ranging in age from 25 to 73 years. Patients in the study were classified as either health workers or non-health workers, with 29 (76.3%) and 9 (23.7%) respectively. Due of restricted resources, the average period of COVID-19 re-infection is 197.6 +/- 97 days without genomic sequence investigation. Comorbidities were discovered in 11 of 38 COVID-19 reinfection patients (29%) Only 6 individuals (15.8%) with COVID-19 reinfection had a history of vaccination. Conclusion: Using convalescent plasma to treat patients with COVID-19 is a rather safe practice. Our analysis demonstrated that the administration of convalescent plasma did not enhance survival or clinical outcomes for COVID-19 patients with moderate to severe disease. Keywords: COVID-19, COVID-19 reinfection, health workers, comorbidity Correspondence: Jatu Aphridasari. Department of Pulmonology and Respiratory Medicine, Dr. Moewardi General Hospital, Surakarta – Indonesia. jatuparu@staff.uns.ac.id. Mobile: +6281289991329.
Physiotherapy Rehabilitation for Accelerating the Recovery of Patient with Anterior Cruciate Ligament Total Reconstruction and Meniscal Repair: A Case Report Saputra, Suryo; Kasumbung, Muhammad Tasa; Larasati, Prihantoro; Setianing, Retno
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.657

Abstract

Background: The Anterior Cruciate Ligament (ACL) is a ligament that functions to limit the movement of the tibia toward the anterior and excessive rotation, while the meniscus serves as shock absorption, load transmission, and the stabilizer of the knee joint. About 22% to 86% meniscal tear incidences occurring along with ACL injuries is. The study aims to determine the role of physiotherapists in the postoperative rehabilitation process of patients of ACL Reconstruction (ACLR) and meniscal repair in preventing postoperative complications and functional abilities of patients. Case Report: The patient was a 35-year-old adult male who suffered a complete tear in the ACL and meniscus of the left knee. The patient underwent ACLR and meniscal repair with arthroscopic surgery 2 years after injury with Bone-Pattelar tendon-bone autograph. 2 weeks post-surgery the patient visited the physiotherapy polyclinic with medical conditions of difficulty in bending and straightening the knee, still feeling pain and thick in the knee area. Results: The physiotherapist program was conducted three times and it was a home program-based exercise. The physiotherapist program and outcomes used in the first phase focused on exercises to improve ROM (Goniometer), oedema management (Medline), pain reduction (Numerical Rating Scale), activation exercises, and surrounding muscle strength (Sphygmomanometer), and improve functional ability (Tegner Lysholm Knee Scale) as well as the provision of home programs Performed by regular monitoring of exercise intensity using isometric, isotonic, and isokinetic exercises, which were given according to the concept of progressive loading. Conclusion: This case study shows that surgery combined with a comprehensive physiotherapy program plan in ACLR and meniscal repair cases, as well as adding home-based exercise programs with intense monitoring, generate more effective results. Keywords: physiotherapy rehabilitation, anterior cruciate ligament total, meniscal repair Correspondence: Suryo Saputra Perdana. Physiotherapist Profession Education Department, Faculty of Health Sciences, Universitas Muhammadiyah Surakarta, Sukoharjo, Central Java, Indonesia. Email: suryo.saputra@ums.ac.id. Mobile: +6281298563988.
Anticoagulant Management of Mechanical Heart Valve Patients During Perioperative Surgery: A Case Report Wasyanto, Trisulo; Yudhistira, Yoga; Anggraini, Nutria; Yasa, Ahmad; Irnizarifka, Irnizarifka
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.667

Abstract

Background: Patients with mechanical heart valves require lifelong oral anticoagulation. It will be a dilemma if a patient with a mechanical heart valve has surgery. This case report aims to discuss how to interrupt oral anticoagulants and bridging therapy in patients with mechanical heart valves who will be undergoing non-cardiac surgery. Case Report: A 26-year-old pregnant woman, G1P0A0, aterm with a mechanical mitral valve, will have elective Sectio Caesarian Transperitonealis (SCTP) surgery and Intra Uterine Device (IUD) insertion. The patient had a history of mitral valve replacement surgery (MVR) in 2014 and was routinely treated with 4 mg of warfarin at night. From the examination, blood pressure was 120/80 mmHg, heart rate was 90 beats per minute, and pulse rate was 90 beats per minute. The ECG examination found sinus rhythm with 1st-degree atrioventricular block, right axis deviation, 90 beats per minute, and left atrial enlargement. We decided to have oral anticoagulant interruption and bridging therapy by stopping warfarin three days before surgery. When the international normalized ratio (INR) falls <2, patients are given heparin injections (UFH) with an APTT target of 1.5-2.0 times from basic APTT. When the patient was about to be operated on, UFH was stopped 6 hours before surgery and resumed 12 hours after surgery. Warfarin was given one day postoperatively. Patients were adjusted to the dose of UFH according to the target. This patient had no thromboembolic events or bleeding before, during, or after surgery. The patient was allowed to be an outpatient and was given home therapy with Warfarin 5 mg at night. Results: We report a case of a 26-year-old female patient with a mechanical mitral valve who was going to undergo elective SCTP surgery and an IUD insertion. Patients at high risk of thrombo¬embolism due to surgery with a high risk of bleeding. Bridging therapy was performed using UFH. In the perioperative period, the patient did not experience thromboembolic events, and bleeding before, during, and after surgery could be well controlled. Conclusion: Perioperative management of patients with mechanical heart valves must be done carefully. Interruption of oral anticoagulants should be carefully considered considering the risk of thromboembolism and bleeding during the perioperative period. Guidelines recommend that in patients with mechanical heart valves, anticoagulation interruption for minor surgeries is avoided. Whereas in patients with major surgery, it is necessary to do bridging therapy with fast-acting anticoagulants such as UFH or LMWH. Keywords: mechanical heart valve, anticoagulant interruption, perioperative, bridging therapy Correspondence: Trisulo Wasyanto. Department of Cardiology and Vascular Medicine, Faculty of Medicine, Sebelas Maret University / Dr. Moewardi Hospital. Jl. Kol. Sutarto 132, Surakarta 57126, Central Java, Indonesia. Email: trisulo.wasyanto@staff.uns.ac.id. ORCID ID: 0000-0001-9900-0497. Mobile: +62811294225.
Meta-Analysis: Application of Theory of Planned Behavior on Acupuncture Therapy Utilization in Cancer Patients with Pain Rahmawati, Fatimah; Demartoto, Argyo; Prasetya, Hanung
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.673

Abstract

Background: Cancer is a health disorder caused by the formation of abnormal cells that grow past the normal cell cycle limit and can attack and spread to other parts of the body. In the Theory of Planned Behavior, one's behavior can be influenced by three main aspects, including attitudes, subjective norms, and behavioral control. The purpose of this study was to estimate perceived benefits, perceived barriers, and subjective norms regarding the use of acupuncture therapy in cancer patients with pain. Subjects and Method: This was a systematic review and meta-analysis. This study uses the PICO model. The meta-analytic study was carried out by searching for articles from databases in electronic form using Google schoolar, PubMed, and Elsevier. Article searches were conducted from 05 February to 10 March 2023. The keywords used were “Theory of Planned Behavior” OR “TPB” AND “Acupuncture” OR “Complemantary Alternative Medicine” AND “Cancer” OR “Pain” AND “Cancer Pain” OR “Cross-Sectional”. The inclusion criteria for this study were complete articles using cross-sectional research, published years from 2007-2022. Analysis of the articles in this study used RevMan 5.3 software. Results: 8 cross sectional studies from North United States and Asia (Korea and Malaysia) were selected for meta-analysis. High perceived benefit (aOR= 1.20; 95% CI= 1.09 to 1.33; p<0.001) and strong subjective norm (aOR= 1.05; 95% CI= 1.01 to 1.08; p= 0.005) increased acupuncture utilization to reduce pain. High perceived barrier reduced acupuncture utilization (aOR= 0.94; 95% CI= 0.91 to 0.97; p < 0.001). Conclusion: High perceived benefit and strong subjective norm increase the use of acupuncture. Strong perceived barrier reduces the use of acupuncture. Keywords: Theory of Planned Behavior, cancer patients with pain, acupuncture therapy
Effect of Social Cognitive Therapy on Mental Improvement in Post Traumatic Stress Disorder: A Meta-Analysis Ariska, Yovita Galuh Eka; Prasetya, Hanung; Murti, Bhisma
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.674

Abstract

Background: Post Traumatic Stress Disorder (PTSD) is a mental disorder that develops after experiencing a very threatening or horrific event. Cognitive behavioral therapy or Cognitive Behavior Therapy (CBT) is one of the most popular therapies. The purpose of this study was to analyze the effect of cognitive behavioral therapy on mental improvement in Post Traumatic Stress Disorder patients. Subjects and Method: This study is a systematic review and Meta-analysis using PICO model. Population: Post Traumatic Stress Disorder patients. Intervention: cognitive behavioral therapy. Comparison: no cognitive behavioral therapy. Outcome: Mental Improvement. The online databases used are Google Scholar, PubMed, and Sience Direct with keywords (“Post Traumatic Stress Disorder” OR “PTSD”) AND (“Cognitive Behavioral Therapy” OR “Cognitive Behavioral Therapy” OR “CBT”) AND (“Randomized controlled trial” OR “RCT”). There were 9 randomized controlled trial studies published in 2005-2023 that met the inclusion criteria. Analysis was performed using RevMan 5.3. Results: A Meta-analysis conducted using 9 RCTs from the United States, Australia, the Netherlands, Sweden, and Thailand. A total sample was 6,088 health workers. Cognitive behavioral therapy reduced PTSD (SMD= -6.32; p= 0.020). Forest plots showed high heterogeneity (I2=73%; p= 0.003), so analysis was conducted using the random effect model. Conclusion: CBT reduces PTSD. Keywords: cognitive behavior therapy, mental improvement, post-traumatic stress disorder, randomized controlled trial
Meta-Analysis the Effects of Hypertension, High Density Lipoprotein, and Diabetes Mellitus on the Risk of Stroke Amalia, Najlah; Widyaningsih, Vitri; Ichsan, Burhannudin
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.675

Abstract

Background: Stroke is defined as an interruption of the blood supply to the brain which is usually caused by a blockage by a blood clot. This causes disruption of the supply of oxygen and nutrients to the brain resulting in damage to brain tissue. This study aims to analyze and estimate the effect of hypertension, high-density lipoprotein, and diabetes mellitus on the risk of stroke. Subjects and Method: This study is a systematic review and meta-analysis using the PRISMA flow chart and the PICO model. Population: adults. Intervention: hypertension, high-density lipoprotein, and diabetes mellitus. Comparison: normal blood pressure, normal HDL, and normal blood sugar. Outcome: strokes. The databases used were PubMed, Google Scholar, Science Direct, and Proquest with keywords (hypertension OR "diabetes mellitus" OR "high-density lipoprotein") AND stroke AND ("cross-sectional" OR "case-control") AND aOR. There were 9 Case-Control studies and 4 Cross-Sectional studies published in 2013-2023 that met the inclusion criteria. Analysis was performed with RevMan 5.3. Results: 13 studies from Oman, Iran, Lebanon, Ghana, Finland, Nigeria, China, Japan, and Saudi Arabia were selected for meta-analysis. Total sample was 71,037. Had history of hypertension (aOR= 5.48; 95% CI = 2.26 to 13.32; p= 0.002) and diabetes mellitus (aOR = 1.93; 95% CI= 1.45 to 2.57; p< 0.001) increased the risk of stroke. High HDL levels reduced the risk of stroke (aOR = 0.46; 95% CI = 0.27 to 0.79; p= 0.004). Conclusion: History of hypertension and diabetes mellitus increase the risk of stroke. However, high HDL levels reduce the risk of stroke. Keywords: hypertension, high-density lipoprotein, diabetes mellitus, stroke.
Effect of Theraband Exercise on Knee Pain Reduction in Osteoarthritis Patients Ramona, Dela; Sudaryanto , Wahyu Tri
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.676

Abstract

Background: Osteoarthritis (OA) is a degenerative joint disease associated with damage to joint cartilage, where a complex joint degradation process occurs, consisting of a repair process in the cartilage, bone, and synovium, followed by a secondary component of the inflammatory process. The primary cause of osteoarthritis is still not known for certain, but there are several risk factors that play a role, namely: age, gender, genetics, obesity, metabolic diseases, and other factors. This study aimed to examine the effect of theraband exercise on reducing knee pain in OA patients. Subjects and Method: This was a quasy experiment study conducted at Dr. Soedjono Hospital, in Magelang, Central Java, from May to June 2023. A sample of 33 knee osteoarthritis patients was selected using purposive sampling. Intervention group (n= 17) received Theraband exercise and control group (n= 16) received usual care. The dependent variable was knee pain. The independent variable was Theraband exercise. Knee pain was measured using a visual analogue scale (VAS). The data were tested using independent t test. Results: After intervention, mean of VAS score in the intervention group (Mean= 5.25; SD= 1.57) was slightly higher than control group (Mean= 5.13; SD= 1.75), but it was statistically non-significant (p= 0.848). Conclusion: Mean of VAS score in the intervention group is slightly higher than control group, but it is statistically non-significant. Keywords: theraband exercise, pain, osteoarthritis knee. Correspondence: Dela Ramona. Study Program of Physiotherapy, Faculty of Health Sciences, Universitas Muhammadiyah Surakarta. Jl. A. Yani Kartasura, Sukoharjo, Central Java, 57162 Email: delaramona26@gmail.com. Mobile: +6281347988116.
Pulmonary Hypertension in Pregnancy: A Case Report Wasyanto, Trisulo; Anggraini, Nutria Widya Purna
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.683

Abstract

Background: Pulmonary Hypertension (PH) is a disease characterized by distressing symptoms and decreased life expectancy due to the narrowing of the blood vessels of the lungs, which often leads to right heart failure. The prevalence of PH in women is 97 cases per million, with 64% of the main causes of PH in pregnancy congenital heart defects, resulting in a very high maternal and fetal mortality rate. Case Report: A 38-year-old G4P1A2 31-week gestational age complained of shortness of breath for 5 days. Physical examination revealed blood pressure was 107/62 mmHg, Heart Rate was 98 beats per minute, respiration 40x per minute, and SpO2 88% with NRM 10 Lpm. The heart examination obtained heart sound I -II regular and a systolic murmur was heard between the left 2nd ribs. Abdominal examination was single fetus, intrauterine, breech presentation, His (+), fetal heart rate 160 beats per minute. vaginal toucher 2 cm in labour. ultrasound examination singles fetal, transverse lies, with an estimated fetal weight of 1600 grams. Echocardiography finding: ASD II L to R shunt with LV EF 60%(T), 62% (S), dilated RA-RV, TR severe, MR mild, High Probability of Pulmonary Hypertension. The patient was diagnosed with Dyspnea, Pulmonary edema caused by cardiogenic, ASD II, High probability of PH, NYHA IV, and Breech presentation in labor. Decided to perform a caesarian section and sterilization. The Male baby was born with 1570 grams Apgar Score 3-5-7. post operation patient was admitted to ICU. Twelve hours after the operation the patient had decreased control and became a PH crisis then the patient was declared dead. Results: The death of the patient, in this case, was caused by cardiogenic shock due to Pulmonary Hypertension Crisis. Conclusion: Early diagnosis along with collaborative and comprehensive management of pulmonary hypertension is needed for good maternal and fetal outcomes. Keywords: pulmonary hypertension, pregnancy, heart disease. Correspondence: Trisulo Wasyanto. Department of Cardiology and Vascular Medicine, Faculty of Medicine, Sebelas Maret University / Dr. Moewardi Hospital. Jl. Kol. Sutarto 132, Surakarta 57126, Central Java, Indonesia. Email: trisulo.wasyanto@staff.uns.ac.id.  Mobile: +62811294225.  
The Effect of Ambon Banana Juice (Musa paradisiaca var. Sapientum Linn) and Sweet Starfruit Juice (Averrhoa carambola L) on Changes in Blood Pressure in the Elderly Men in the Community Health Center Work Area Tarus, Kupang Regency Manek, Nusthen Aries; Datta, Frans Umbu; Refli, Refli; Lalel, Herianus J.D.; Manongga, Stefanus P.
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.685

Abstract

Background: Hypertension is a health problem that often occurs in society. Uncontrolled hypertension can trigger degenerative diseases such as heart disease and kidney failure. One of the therapies used to lower blood pressure is Ambon banana and sweet star fruit therapy. Subjects and Method: Research on elderly men suffering from hypertension in the Tarus Community Health Center working area used a Quasi-Experimental pretest–posttest with a Control Group research design. The number of samples in this study was 20 elderly men using a simple random sampling method. The dependent variable in this study was blood pressure, while the independent variable was the administration of Ambon banana juice, sweet star fruit juice, and a combination of Ambon banana juice and sweet star fruit juice. The measuring instrument used in this research is a questionnaire. The data analysis used in this research is Anova and Post hoc. Results: The average blood pressure in the elderly decreased after being given Ambon Banana Juice, Sweet Starfruit Juice, and a combination of Juices. The greatest reduction in blood pressure occurred in the group given Ambon banana juice (Mean= 140 mmHg; p=0.002), compared to sweet starfruit juice (Mean= 148 mmHg; p= 0.036), and these results were statistically significant. The juice combination also reduced the average blood pressure, but the results were not statistically significant (Mean= 156 mmHg; p= 0.454). Conclusion: The average blood pressure in the elderly decreased after being given Ambon Banana Juice, Sweet Starfruit Juice, and a combination of Juices. Keywords: hypertension, Ambon banana juice, sweet star fruit juice Correspondence: Nusthen Aries Manek. Universitas Negri Nusa Cendana Kupang. Jl. Adisucipto Penfui, Kupang, Nusa Tenggara Timur. Email: Nusthen2503@gmail.com. Mobile: 082144927619.

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