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Proceedings of the International Conference on Applied Science and Health
ISSN : 25794434     EISSN : -     DOI : -
Core Subject : Health, Education,
Proceedings of the International Conference on Applied Science and Health is a conference collection of technical papers freely accessible to scholars over the world. Articles featured vary areas of efforts to develop health and well-being for better society such as factors of illness, epidemiology, health promotion, health policy, nutrition, environmental health and safety, nursing and midwifery, and other sciences related to health development.
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Articles 135 Documents
Search results for , issue "No 4 (2019)" : 135 Documents clear
ANTIDIABETIC EFFECT OF COMBINED Muntingia calabura L. LEAF EXTRACT AND METFORMIN ON RATS Nugroho, Adhy; Primanagara, Risnandya; Basyir, Pahmi Budiman Sahputra
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Diabetes mellitus is a disease that causes blood glucose levels to increase. There are several therapies that can be done to reduce blood glucose levels in diabetes such as metformin, biguanides medicine and kersen (Muntingia calabura L.) leaves as an alternative. Treatment with combination of both is expected to further reduce blood glucose levels. This study aims to measure the effectiveness of the combination of metformin and Muntingia calabura L. leaf extract on blood glucose levels. Methods: This was an experimental research with pretest-posttest control group. The samples were 24 Sprague-Dawley rats divided into 4 groups, first group (K1) negative control was given only aquadest, second group (K2) positive control (+) was given 45 mg/kgBW metformin, third group (K3) was treated with 300 mg/kgBW Muntingia calabura leaf extract, and the fourth group (K4) was given the combination of 300 mg/kgBW Muntingia calabura leaf extract and  45 mg/kgBW metformin. Blood glucose levels were measured and analyzed using paired t-test and one-way ANOVA. Results: The combination of 300 mg/kgBW of Muntingia calabura extract and 45 mg/kgBB of metformin reduces 131.77 ± 3.57 mg/dl of blood glucose levels (p<0.05). This result is better than only metformin (92.68 ± 3.10 mg/dl) or only Muntingia calabura leaf extract (91.70 ± 4.40 mg/dl). There is a possibility that the synergistic effect of Muntingia calabura leaf extract and metformin caused the increased effectivity in reducing blood sugar level.Conclusion: The combination of Muntingia calabura and metformin is more effective in reducing blood glucose levels compared to a single dose of metformin or Muntingia calabura L. extract alone.
ANTIMICROBIAL STEWARDSHIP STRATEGY TO REDUCE LENGTH OF STAY AND COST OF ANTIBIOTIC CONSUMPTION: A SYSTEMATIC REVIEW Damayan, Anak Agung Istri Agung Sri Stuti; Maharjana, Ida Bagus Nyoman; Nurwahyuni, Atik
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Reducing the cost of care and length of stay for patient in hospital are important to monitor the benefits of implementing an antimicrobial management program. An antimicrobial management program is a strategy to decrease Antimicrobial Resistance (AMR) that affect to the treatment of the patient. One of the antimicrobial management programs is Antimicrobial Stewardship Programs (ASP). This study aims to determine the appropriate strategies in the application of Antimicrobial Stewardship Programs (ASP) that can reduce the length of stay and cost of antibiotic consumption for patient in hospital.Methods: This study was a systematic review that used PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines. Data obtained from Electronic databases ProQuest and Medline (PubMed) that published five years times span. By using keywords such as antimicrobial stewardship, antimicrobial resistance, length of stay, length of the hospital and patient cost to find the relevant journal. Results:  The search found 3,541 studies, of which 26 studies were included in the systematic review. After excluded the article review, there were 9 studies that used quasi-experimental, observational cohort studies and Randomized Control Trial (RCT). These studies conducted majority in Europe and USA, only 1 study that conducted in Asia. Analysis of the studies found out that 6 of 9 studies mentioned if ASP can reduce the length of stay of the patient in hospital. Only 3 of 9 studies that examined the effect of ASP in cost of care and these 3 studies mentioned ASP can reduce the cost of care. Conclusion: This study showed that implementing ASP can reduced the length of stay and antibiotics consumption among patient in hospital by manage the antimicrobial use, conduct audits and feedback in an appropriate step, and intravenous to oral switch program.
MICROENCAPSULATION OF KARAMUNTING LEAF EXTRACT (Rhodomyrtus tomentosa) AS AN INSTANT DRINK POWDER Supriyono, Teguh; Sera, Agnescia Clarissa
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Backgrounds: Karamunting (Rhodomyrtus tomentosa), a local wild plant from Central Kalimantan, Indonesia is believed by the Dayak tribe to treat diabetes mellitus. Based on the literature review, there have been no studies related to Karamunting focused on processed products in practical dosage forms in the form of instant powder, which has the longest shelf life. This study aims to explore the solubility and percentage of insoluble solids of Karamunting leaf powder that has been encapsulated with the addition of Maltodextrin. In addition, an assessment of the sensory attributes of Karamunting leaf drinks was also carried out. Methods: This study was used an experimental with applied the Randomized Block Design (RBD) design with 2 factors, comparing the number of Karamuting leaf extracts and the concentration of Maltodextrin to produce a formula of 0.5L:5%, 0.5L:10%, 0.5L:15%, 1L:5%, 1L:10% and 1L:15%. This research conducted in the Laboratory of Agricultural Product Technology, Gadjah Mada University, Yogyakarta, Indonesia from November to December 2018. Results: The application of spray dryer produced fine powder of Karamunting drink. It has a distinctive aroma and its color was ranged from bright cream to slightly brownish. Addition of Maltodextrin significantly accelerated powder?s solubility and decreased its yield (p<0.05). Panelists tend to prefer products with 1 L of Karamunting leaf extract and 10% Maltodextrin. Conclusions: Solubility rate of Karamunting leaf extract is strongly influenced by the concentration of Maltodextrin. The higher the concentration of Maltodextrin, the faster the product will be dissolved. Addition of Maltodextrin significantly reduced the total of insoluble solids. However, antidiuretic activity of Karamunting drink should be investigated to prove its health claim.
DETERMINANT OF CHRONIC ENERGY MALNUTRITION OF PREGNANT WOMEN AT KARANG BANDAR LAMPUNG HEALTH CENTER Muthiatulsalimah, Mutiara Ayu; Rahayu, Sri
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: The most common nutritional problem experienced by pregnant women is Chronic Energy Deficiency (CED), which may be caused by nutritional intake consumed, socio-economic and history of disease / infection before becoming pregnant. But the cause of CED is not only a problem of lack of food but also due to the influence of lifestyle, workload and nutritional status of the mother during pregnancy. This study aims to determine the relationship between lifestyle during pregnancy, workload during pregnancy, nutritional status during pregnancy with Genesis CED in Pregnant Women. Methodology: Quantitative research method with cross sectional design. The population of this study were all pregnant women who checked their pregnancy at the Public Health Center Karang City Bandar Lampung. Sampling technique using total population sampling is as much as 40 people. Data was collected through primary (questionnaire) and secondary (KIA book) data collection. Data analysis was performed using chi-square test. Results: Results of this study showed that there was no significant relationship between lifestyle with the CED incidence in pregnant women. Meanwhile, the results showed that workload and nutrition were significantly associated with the CED incidence in pregnant women. Conclusion: This study recommends that there is a need for coordination between puskesmas and city health offices to provide supplementary food for pregnant woman and provide education to woman about the importance of nutrition during pregnancy before marriage, such as counseling in order to prevent CED occurrence during pregnancy.
THE CORRELATION OF EDUCATION AND SOCIAL ECONOMIC LEVELS WITH ANTIBIOTIC SELF-MEDICATION IN THE COMMUNITY OF CIREBON Handayani, Tridaya Putri; Satrianugraha, Muhammad Duddy; Pratiwi, Witri; Mulyaningsih, Ruri Eka Maryam
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: People in developing countries, like Indonesia, often conduct self-medication. One of the most common drugs used in self-medication is antibiotics. Antibiotics should be used with caution since it can cause antibiotic resistance and possible unwanted side effects of the drug. There are several factors that influence self-medication behavior such as education and socio-economic levels. This research aims to find the correlation between education and social economic levels with antibiotic self-medication in the community of Cirebon.Method: This study was an analytical survey with cross-sectional method. This study was conducted from December 2018 to February 2019. A total of 300 respondents were recruited as samples using consecutive sampling technique. The respondents were recruited from 5 different pharmacies from each sub-district in Cirebon City and a validated questionnaire were used to obtain data. The collected data are analyzed using the Spearman correlation test.Results: The results of this study show that there was a significant but weak positive correlation of education level (r=0.224, p=0.001) and socio-economic (r=0.210, p=0.001) with self-medication using antibiotics. Conclusion: There is a significant positive correlation between education and socio-economic levels with antibiotic self-medication.
FOOT REFLEXOLOGY FOR WOMEN AND FETAL WELLBEING IN LABOR : A REVIEW Hakim, Riska Ismawati; Karimah, Nahdiyah; Saptyani, Putri M; M, Sri Wahyuni
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: The secretion of catecholamine and epinephrine due to excessive fear and anxiety during labor will increase the intensity of pain and potentially prolonged labor. Reflexology massage leads to release endorphins and enkephalins which have an analgesic effect five times greater than morphine, creates a deep feeling of comfort and balance of mind so the stress symptoms are reduced, and improves the outcomes of labor. This study aims to analyze the effects of foot reflexology for women and fetal wellbeing in labor. Methodology: This systematic review used PRISMA-P (Preferred Reporting Items for Systemic Review and Meta-Analysis Protocols). The keywords used were reflexology or foot feflexology, pain relief, labor pain, primiparaous, effect or effectiveness. Articles were searched through databases PubMed, Google Scholar, and Science Direct. Inclusion were articles that discusssed about reflexology and its effects in labor, experimental research and written in English. The selected articles were excluded for irrelevant titles and abstracts, non-full text, research under 2009 and duplicate articles. From 78 articles, only 8 articles were included in this systematic review. Results: This study found that foot reflexology can reduce the intensity of labor pain. It was also decreased duration, anxiety, hemorrhage rate, systolic and diastolic blood pressure, pulse and increased uterine contractions, Apgar scores and maternal satisfaction with a highly statistical significant. Conclusion: Foot reflexology could decrease the intensity of labor pain, anxiety, duration, maternal complications and increase uterine contractions. In addition to improve labor outcomes and mother satisfaction. It is recommended as non pharmacological method which can be applied in maternity hospitals to improve women and fetal wellbeing during labor.
THE EFFECT OF ANTIEMETIC FOR GALACTOGOGUE Rahani, Sukma Marthia; Sjaaf, Amal Chalik
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Breastmilk provides nutrition that newborn and baby need during early stage of their lives. Breastmilk production can be increased by giving the mother oxytocin or prolactin enhancement that called galactogogue during breastfeeding. Giving galactogogue to mother bring side effect such as nausea, vomit, and insomnia. The example of galactogogue are domperidone and metoclopramide. Domperidone and metoclopramide not only useful to increase the breastmilk production as galactogogue but also can be used as antiemetic to reduce the effect in the galactogogue. This study aims to examine the effect of antiemetic for galactogogue during breastfeeding. Methods: This study was a systematic review that used PRISMA guidelines. Data obtained from Electronic databases ProQuest and Google Scholar that published between 2015 and 2018. By using keywords such as effect, antiemetic, galactogogue to find the relevant journal. Results: The search found 58 studies, of which 7 studies were relevant to analyze in this study. Majority of these studies used Randomized Control Trial (RCT) and 1 study used case study. Analysis of the studies found out that domperidone and metoclopramide can be used as antiemetic for galactogogue. Domperidone was not enter the blood circulation and did not interfere the breastmilk production
BRINGING MEDICAL GENETICS TO THE PUBLIC: THE CHALLENGES FOR INDONESIAN MEDICAL FACULTIES Sulistiyana, Catur Setiya
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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TRAVEL MEDICINE MANAGEMENT FOR THE ANTICIPATION OF INFECTIOUS DISEASES IN SOUTHEAST ASIA: A SYSTEMATIC REVIEW  Dewi, Ni Putu Ayu Prima; Bachtiar, Adang
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Travelling abroad have various health risks such as sudden and significant changes in altitude, humidity, temperature and exposure to a variety of infectious diseases. Travel medicine concept is needed to provide information to professional health services not only on risk of infectious diseases but also to ensure the personal safety of travellers and to minimize environmental risk during travel. The Objective of this study is to investigate the practices of travel medicine management for the anticipation of infectious disease spread by travellers. Methods: This study used systematic literature  review based on PRISMA (Prefered Reporting Items for Systematic Reviews & Meta-Analyses)protocol to identify all the published articles using relevant keywords.We searched in Scopus (Elsevier), Science direct (Web of Science), Cochrane library and Pubmed. Period of study was between 2005 and 2018. In total, there were eight studies that discussed travel medicine management regarding the anticipation of infectious diseases in Southeast Asia, which includes the spread and narrative synthesis. Results: From 126 authors finally include 8 papers in this review. Almost all of the management of travel medicine can reduce the risks of travel-related diseases. The travel medicine management explained how to effectively prevent the spread of infectious diseases, for example dengue, malaria, rabies, zika virus, diarrhea and respiratory syndrome. Those diseases can easily spread when the travellers body immunity decreases or when they are exhausted during the trip. Thus, it is necessary for the travellers to anticipate the spread of diseases by knowing the information of particular diseases in a country or a region that will be visited and having prophylaxis or vaccination before travelling. Conclusions: The travel medicine management can significantly impact on the anticipation of infectious diseases spread by travellers since the practices require the latest facts and information about the epidemiology of infectious health risks worldwide.The recommendation for future research is to review more travel medicine management studies in order to get deeper understanding.For Policy maker, it is suggested to design policy to improve and updating knowledge. 
THE EFFECT OF ORALLY ADMINISTERED CATFISH (Clarias gariepinus) SKIN AND MEAT ON EPITHELIALIZATION THICKNESS AND COLLAGEN DENSITY IN INCISION WOUND OF WISTAR RAT (Rattus norvegicus) Baihaqi, Muhammad Irsyad; Satrianugraha, Muhammad Duddy; Pratamawati, Tiar M; Nauphar, Donny
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Alternative medicine using animal is still rare whereas Indonesia have a lot of potential natural resources. Catfish is easily found animal in Indonesia and is common consumed as nutriment sources contains albumin, amino acid and fatty acids which plays an essential role of wound healing process. This study will determine effect of orally administered catfish (Clarias gariepinus) skin and meat on epithelialization thickness and collagen density in incision wound of white male rat (Rattus norvegicus).Methods: This experimental post-test only group design used 30 white male rat (Rattus norvegicus), that randomly divided into 4 tratment goup and one control group. The treatment group was given 12,5 mg/g W, 25 mg/g W, 37,5 mg/g W and 50 mg/g W dose of catfish (Clarias gariepinus) skin and meat flour, in the other hand the contol group were given aquades. Non-parametric analyses using Kruscall-Wallis and Mann Whitney test were used to compare epithelization thickness and collagen density.Result: The comparison results of epithelialization thickness between group C with TGI, C with TG2, C with TG3 and C with TG4 showed significant differences (p<0.05). TG4 was the thickest of all groups. Significant differences were also observed in collagen density result between C with TGI, C with TG2, C with TG3 and C with TG4 (p <0,05) TG4 showed the highest density of all groups.Conclusion: Catfish (Clarias gariepinus) skin and meat flour with 50 mg/200g W dose is effective for wound healing and increasing epithelial thickness and collagen density in Wistar rat (Rattus norvegicus) incision wounds.

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