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Contact Name
Amin Fatoni
Contact Email
aminfatoni@unsoed.ac.id
Phone
-
Journal Mail Official
j.molekul@gmail.com
Editorial Address
Jl. Dr. Soeparno No.61 Karangwangkal, Purwokerto, Jawa Tengah 53
Location
Kab. banyumas,
Jawa tengah
INDONESIA
Molekul: Jurnal Ilmiah Kimia
ISSN : 19079761     EISSN : 25030310     DOI : -
MOLEKUL is a peer-reviewed journal of chemistry published by the Department of Chemistry, Faculty of Mathematics and Natural Sciences, Jenderal Soedirman University, Indonesia. Publishing frequency 2 issues per year, on May and November. This Journal encompasses all branches of chemistry and its sub-disciplines including Pharmaceutical, Biological activities of Synthetic Drugs, Environmental Chemistry, Biochemistry, Polymer Chemistry, Petroleum Chemistry, and Agricultural Chemistry.
Arjuna Subject : -
Articles 331 Documents
PREPARASI DAN KARAKTERISASI KOMPLEKS KITOSAN HIDROGEL-TEMBAGA(II) Risfidian Mohadi; Nurlisa Hidayati; Melany N.R
Molekul Vol 2, No 1 (2007)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.295 KB) | DOI: 10.20884/1.jm.2007.2.1.31

Abstract

Research about preparation and characterization complex of chitosan hydrogel–copper(II) had been done. Chitosan hydrogel was obtained from deacetylation of chitin which was isolated from crab shells. Characterization included determination of N-total, Corganic , deacetylation degree, and FTIR spectroscopy. The results of research showed that obtained chitosan had 7,9571% N-total, 2,767% Corganic, and 71,486% deacetylation degree. FTIR spectrum of chitosan showed the increasing in percentage of transmitant from C=O group and the shifting in wavenumber from 1561,5 to 1563 cm-1 indicated N-H bending. Generally, FTIR spectrum of chitosan hydrogel showed the shifting to higher wavenumbers caused by changing in bond angles of chitosan group. FTIR spectrum of chitosan hydrogel-copper(II) complex showed that absorption regions of N-H group becoming wide and the shifting in wavenumber from 1594,74 to 1542,9 cm-1 whichindicated N-H bending because of copper(II) bonding to N-group of chitosan.
PENGARUH PENAMBAHAN SORBITOL DAN KALSIUM KARBONAT TERHADAP KARAKTERISTIK DAN SIFAT BIODEGRADASI FILM DARI PATI KULIT PISANG Senny Widyaningsih; Dwi Kartika; Yuni Tri Nurhayati
Molekul Vol 7, No 1 (2012)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.847 KB) | DOI: 10.20884/1.jm.2012.7.1.108

Abstract

Kulit pisang merupakan limbah dari industri pembuatan keripik pisang. Kandungan pati dalam kulit pisang dapat dimanfaatkan untuk dibuat menjadi film biogedradable. Untuk memperbaiki sifat film yang dihasilkan maka ditambahkan sorbitol sebagai plasticizer dan kalsium karbonat sebagai filler. Hasil penelitian menunjukkan bahwa film berbahan dasar pati dari kulit pisang memiliki densitas antara 3,11-6,12 g/cm3; higroskopisitas antara 3,55-7,59%; laju transmisi uap air antara 0,0017-0,0021 g/jam cm2; kelarutan dalam air antara 2,54-59,01%; kelarutan dalam asam 4,05-87,86%; daya regang antara 2,73-179,61 MPa; panjang putus antara 1,95-19,81 MPa; ketahanan sobek antara 2,50-26,32 MPa; dan pada uji biodegradasi dalam tanah mengalami penurunan berat film antara 5,73-85,08%.
Surface-enhanced Raman Scattering (SERS) Substrate of Colloidal Ag Nanoparticles Prepared by Laser Ablation for Ascorbic Acid Detection Teguh Endah Saraswati; Yudha Pratama Putra; Mohammad Rifqi Ihsan; Isnaeni Isnaeni; Yuliati Herbani
Molekul Vol 13, No 1 (2018)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (563.834 KB) | DOI: 10.20884/1.jm.2018.13.1.409

Abstract

Ag nanoparticles were synthesized by laser ablation using an Ag plate in distilled water. This method was performed using a laser with a wavelength of 532 nm and energy of 30 mJ for 60 min. Ag nanoparticles successfully formed, confirmed by the selected area electron diffraction (SAED) which revealed four principal crystal planes of (111), (200), (220) and (311). The size distribution of Ag nanoparticles ranged from 5 to 40 nm, as estimated from electron imaging observed by transmission electron microscope (TEM). Ascorbic acid was used as the analyte to test the characteristics of surface-enhanced Raman scattering (SERS) of colloidal Ag nanoparticles. The concentration of ascorbic acid (1.0, 0.5 and 0.25 wt%) and incubation time (0 and 6 h) were varied to determine the limit of detection and the effect of incubation time. The Raman scattering spectroscopy results showed that the colloidal Ag nanoparticle substrate improved the signals for detection of ascorbic acid.
PENGARUH TRITERPEN TOTAL PEGAGAN (Centella asiatica (L) Urban) TERHADAP FUNGSI KOGNITIF BELAJAR DAN MENGINGAT PADA MENCIT JANTAN ALBINO (Mus musculus) YANG DIHAMBAT DENGAN SKOPOLAMIN Herlina Herlina
Molekul Vol 5, No 2 (2010)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (151.819 KB) | DOI: 10.20884/1.jm.2010.5.2.81

Abstract

Pegagan (Centella asiatica (L) Urban) has been described to posses CNS effects such as improving cognitive function, learning and memory. The aim of the research was to evaluate the effects of total triterpen’s pegagan extract on cognitive functions as the learning and memory performance in male albino mice (Mus musculus) inhibited by scopolamine. The research design was Complete Randomized Design (RAL) – factorial on thirty six mice divided into 4 groups. One control group received only aquabidest (negative control). Three treatment groups received total triterpen 16 mg/kg BW, 32 mg/kg BW orally and piracetam 500 mg/kg BW by intra peritoneally (positive control) for 21 days. Data indicating learning and memory process of all subjects were obtained from one-trial passive avoidance test. Data were analyzed by two way ANOVA and BNT (p<0,05). Result showed that total triterpen 32 mg/kg BW had significantly prolonged the retention time compared to control group indicating improvement in cognitive function (505,03 second vs -18,53 second) (p<0,05) and it was not significantly different to piracetam 500 mg/kg BW group (505,03 second vs 522,48 second) (p>0,05). In conclusion, total triterpen from pegagan (Centella asiatica (L) Urban) improved learning ability and memory of male albino mice (Mus musculus) even though, it was inhibited by scopolamine.
SYNTHESIS OF CHITOSAN/TiO2 COMPOSITE AND ITS COATING ON SURFACE OF TEXTILE SUBSTRATE Agung Nugroho Catur Saputro
Molekul Vol 11, No 2 (2016)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (628.05 KB) | DOI: 10.20884/1.jm.2016.11.2.243

Abstract

Coatings of composite Chitosan/TiO2 on a surface of textile have been successfully performed. These coatings were done by dip-coating method. The variety of coatings textile were performed in 2, 4, and 6 coatings. The textile was coated by composite of Chitosan/TiO2 then characterized by FTIR Spectrometry, X-Ray Diffraction and Scanning Elelectron Microscopy (SEM). Based on the spectra of FTIR Spectrofotometry, XRD difractogram and imaging of SEM it can be concluded that hypothesized composite of Chitosan/TiO2 was coated on surface of textile but that hypothesis were still very weak and it need to be examined by performance test.
PENGARUH MEDIUM PERENDAM TERHADAP SIFAT MEKANIK, MORFOLOGI, DAN KINERJA MEMBRAN NATA DE COCO Senny Widyaningsih; Hartiwi Diastuti
Molekul Vol 3, No 1 (2008)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (349.457 KB) | DOI: 10.20884/1.jm.2008.3.1.44

Abstract

Nata de coco is bacterial cellulose which is produced by Acetobacter xylinum in fermentation process of coconut water. Based on its properties, nata de coco can be used as a membrane. Soaking medium in purification of nata de coco gel can influence structure, morphology, and performance of nata de coco membrane. First medium was NaOCl 0.05% and NaOH 5%, Second medium was ultrasonic. Third medium was NaOH 1% and CH3COOH 1%. Mechanical property were analysized based on its tensile strength. Morphology of membrane was analysized using SEM. Performance of membrane was determined based on its permeability. The result showed that nata de coco membrane which had the best value on mechanical properties, morphology, and performance was membrane in third medium.
AKTIVITAS ANTIBAKTERI Eschericia coli PADA MINYAK ATSIRI BATANG GENOAK (Acorus calamus) ASAL PULAU TIMOR Sherlly M. F. Ledoh; Reiner I. Lerrick; Debora Ratu
Molekul Vol 8, No 1 (2013)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (389.563 KB) | DOI: 10.20884/1.jm.2013.8.1.120

Abstract

Telah dilakukan uji aktivitas antibakteri Eschericia coli (E. coli) minyak batang genoak (Acorus calamus). Penelitian ini dilakukan melalui destilasi uap batang genoak yang diikuti analisis komposisi kimianya menggunakan GC-MS, dan uji antibakteri terhadap bakteri E. coli menggunakan metode hitung cawan. Hasil penelitian diperoleh minyak genoak dengan rendemen 0,17% dan asaron sebagai komponen utama minyak genoak sebesar 89,81%. Minyak genoak dapat menghambat pertumbuhan bakteri E. coli sebesar 95,76% pada kosentrasi 10% (v/v).
The Synthesis of MnFe2O4-Activated Carbon Composite for Removal of Methyl Red From Aqueous Solution Fahma Riyanti; Poedji Loekitowati Hariani; Widia Purwaningrum; Elfita Elfita; Shella Santika Damarril; Iqlima Amelia
Molekul Vol 13, No 2 (2018)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (459.07 KB) | DOI: 10.20884/1.jm.2018.13.2.435

Abstract

In this study, MnFe2O4-activated carbon composite was synthesized by co-precipitation method and applied to adsorb methyl red dye. MnFe2O4-activated carbon composite was made with the mass ratio of activated carbon and MnFe2O4 of 1:2. The composite characterization by using X-Ray Diffraction, Fourier Transform Infrared Spectroscopy, Scanning Electron Micrograph, and Energy-Dispersive X-Ray Spectroscopy, the surface area using the Brunauer, Emmett and Teller and magnetic properties by using Vibrating Sample Magnetometer. The adsorption parameters include contact time, and adsorbent weight. The spectra of FTIR MnFe2O4-activated carbon composite analysis show the presence of Fe-O and Mn-O which is not present in the spectra of activated carbon. SEM analysis shows that the composite has pores and MnFe2O4 oxides are spread on its surface. The composition of the composite consists of C, O, Fe, and Mn. The composite has a surface area of 143.992 smaller than that of the activated carbon of 217.697 m2/g. However, the composite has magnetic properties with the saturatization magnetization of 17.91 emu/g. The optimum condition of the composite for adsorption of methyl red was obtained at a weight of 0.15 g, and contact time of 100 minutes. The adsorption of the composite was in accordance by pseudo-second-order kinetic and Langmuir isotherms with adsorption capacity of 81.97 mg/g.
AKTIVITAS ANTIPROLIFERASI ISOLAT 4 EKSTRAK PETROLEUM ETER DAUN Phaleria macrocarpa (Scheff.) Boerl. PADA SEL KANKER SERVIKS MANUSIA (HeLa) Dwi Utami
Molekul Vol 6, No 2 (2011)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (241.389 KB) | DOI: 10.20884/1.jm.2011.6.2.92

Abstract

Kanker serviks merupakan penyebab kematian kedua wanita di Indonesia setelah kanker payudara. Mahkota dewaPhaleria macrocarpa (Scheff.) Boerl telah dikenal oleh masyarakat dan digunakan secara tradisional untuk pengobatan kanker. Ekstrak petroleum eter daun mahkota dewa menunjukkan aktivitas antiproliferasi pada sel kanker serviks manusia (HeLa) dengan IC50 9 µg/ml (Kintoko dan Hawariah, 2007). Tujuan penelitian ini untuk mengetahui aktivitas antiproliferasi isolat 4 ekstrak petroleum eter terhadap sel kanker serviks manusia (HeLa).Serbuk daun mahkota dewa disokletasi dengan petroleum eter, kemudian difraksi dengan etil asetat hingga diperoleh fraksi etil asetat. Fraksi etil asetat dilakukan kromatografi preparatif dengan fase gerak heksana : etil asetat (9:1). Aktivitas antiproliferasi terhadap sel HeLa ditetapkan harga LC50dan doubling time melalui uji sitotoksik dan pengamatan kinetika proliferasi dengan metode MTT.Hasil isolasi dengan kromatografi preparatif diperoleh lima isolat masing-masing dengan harga Rf : 0,05 ; 0,10 ; 0,20 ; 0,60 ; dan 0,90. Harga LC50 dari isolat 4 adalah sebesar 82,091 µg/ml. Isolat 4 menunjukkan penghambatan pertumbuhan sel HeLa dengan memperpanjang doubling time (16,495 jam) dibanding kontrol sel (10,170 jam).
PENERAPAN METODE ELEKTROKIMIA UNTUK PENURUNAN CHEMICAL OXYGEN DEMAND (COD) DAN TOTAL SUSPENDED SOLID (TSS) LIMBAH CAIR INDUSTRI TAHU Suyata Suyata; Irmanto Irmanto; Undri Rastuti
Molekul Vol 10, No 1 (2015)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (480.607 KB) | DOI: 10.20884/1.jm.2015.10.1.176

Abstract

Limbah cair industri tahu memiliki nilai COD dan TSS yang tinggi, apabila dibuang ke badan perairan akan menyebabkan pencemaran lingkungan. Oleh karena itu, perlu dilakukan penurunan nilai COD dan TSS limbah cair industri tahu tersebut sebelum dibuang ke badan perairan. Penurunan nilai COD dan TSS limbah cair industri tahu dapat dilakukan menggunakan metode elektrokimia. Penelitian ini bertujuan untuk mengetahui pengaruh voltase, jarak elektroda, pH, dan waktu elektrolisis terhadap penurunan nilai COD dan TSS limbah cair industri tahu.  Eksperimen dilakukan dengan mengelektrolisis limbah cair industri tahu menggunakan anoda PbO2 dan katoda Pb. Hasil penelitian menunjukkan bahwa dibawah kondisi optimum pada voltase 12V, jarak elektroda 1 cm, pH 1 dan waktu elektrolisis selama 120 menit, penurunan nilai COD dan TSS mencapai 96,33% dan 87,87%