cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Syafira Dwi Cahyani
Contact Email
adminjifi@univpancasila.ac.id
Phone
+6287780957284
Journal Mail Official
syafira.ffup@univpancasila.ac.id
Editorial Address
Editorial Office: Lenteng Agung St, Srengseng Sawah District, Jagakarsa Regency, Jakarta Selatan, Special Region of Jakarta 12640, Indonesia.
Location
Kota adm. jakarta selatan,
Dki jakarta
INDONESIA
Jurnal Ilmu Kefarmasian Indonesia
Published by Universitas Pancasila
ISSN : 16931831     EISSN : 26146495     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health
Jurnal Ilmu Kefarmasian Indonesia (JIFI) mainly focuses on a current topic in Pharmaceutical Sciences are also considered for publication by the Journal. Discussions on a topic in Pharmaceutical Sciences, Clinical Sciences, and Social Behaviour Administration. Detailed scopes of articles accepted for submission to JIFI are: 1. Pharmaceutical Biology 2. Pharmaceutical Chemistry. 3. Pharmaceutical Technology. 4. Biomedical and Clinical Pharmacy. 5. Social Pharmacy and Administration.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 721 Documents
 29   30   31   32   33 
Penetapan Simultan Kadar Fenilpropanolamin Hidroklorida dan Klorfeniramin Maleat dalam Tablet secara Spektrofotometri FARIDAH FARIDAH; NOVI YANTIH; NETTY HERAWATI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 6 No 1 (2008): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1725.079 KB)

Abstract

Simultaneous determination of phenylpropanolamine hydrochloride and chlorpheniramine maleate in tablets by spectrophotometry was carried out. The method is based upon total absorption of the two compounds in a mixture which can be applied to quantify each ofthe component. The absorption of phenylpropanolamine hydrochloride and chlorpheniramine maleate in 0.1 N hydrochloric acid were measured at the maximum Wavelength of phenylpropanolamine hydrochloride (256.7 nm) and that of chlorpheniramine maleate (262.6 nm), with a correlation coefficient of 0.999. A high precision could be obtained as shown by the CV of 0.2139-0.4962% for phenylpropanolamine hydrochloride and 0.3182- 0.5289% for chlorpheniramine maleate, While the recoveries ofphenylpropanolamine hydrochloride and chlorpheniramine maleate were 99.93% ± 0.43% and 99.76% ± 0.39%, respectively. The proposed method is simple, with a high accuracy and suitable for the simultaneous determination ofphenylpropanolamine hydrochloride and chlorpheniramine maleate in tablets, Without prior separation.
Spektofotometri Derivatif dan Aplikasinya dalam Bidang Farmasi Liliek Nurhidayati
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 2 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1078.4 KB)

Abstract

Derivative spectrophotometry is a method for the simultaneous determination of drugs mixtures due to their overlapping spectra. Since the practical introduction of the concept of spectral data derivatization, the derivative spectrophotometry technique was applied. This review describes the theoretical and instrumental aspects of derivative spectrophotometry and some of its applications in pharmaceutical analysis since 1999.
Identifikasi Senyawa dari Ekstrak Air Rimpang Bangle (Zingiber cassumunar Roxb.) SRI HARTATI; MEGAWATI MEGAWATI; NINA ARTANTI; MEILYAWATI L.; M. HANAFI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 11 No 2 (2013): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (444.458 KB)

Abstract

In a preliminary study on search of marker compounds from raw material phytopharmaceutical water extracts of medicinal herbs bangle (Zingiber casumunar Roxb.) three compounds, namely (E)-4-(3’,4’-dimethoxyphenyl)but-3-en-1-yl acetate (1), (E)-4(3’,4’-dimethoxyphenyl) but-3-en-1-1-ol (2) and 2-Methoxy-8-(3,4-dimethoxyphenyl)-1,4-napthoquinone (3) had been found. The isolation was done by partition and combination of chromatography techniques. The isolated pure compound was analyzed by spectroscopy methods of NMR proton and carbon one and two-dimensional, LC-MS and IR-spectrophotometry IR
Jumlah Kunjungan, Profil Pengobatan, dan HRQoL Pasien Rawat Jalan DM Tipe 2 pada Era JKN YUSI ANGGRIANI; MITA RESTINIA; NURLAYLI NURLAYLI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 14 No 2 (2016): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1993.384 KB)

Abstract

Asuransi kesehatan pemerintah bertransformasi dari Asuransi Kesehatan (ASKES) menjadi Jaminan Kesehatan Nasional (JKN) sejak 1 Januari 2014. Terdapat perbedaan metode pembayaran antara ASKES dan JKN. ASKES menggunakan metode fee for services dan JKN menggunakan metode INA-CBGs. Tujuan penelitian yaitu untuk melihat dampak pelaksanaan JKN terhadap jumlah kunjungan, profil pengobatan, dan Health Related Quality of Life (HRQoL) pada pasien DM tipe 2 rawat jalan pada salah satu RS tipe B di Jakarta. Penelitian dilakukan secara time series longitudinal. Total sampel yang memenuhi kriteria inklusi sebanyak 103 pasien. Pasien laki-laki sebanyak 36(35%) dan perempuan 67(65%). Terdapat 98% pasien memiliki usia lebih dari 45 tahun. Sebanyak 95(92%) pasien dengan diagnosa DM tanpa komplikasi dan 8(8%) pasien DM dengan komplikasi. Setelah pelaksanaan JKN, terdapat penurunan jumlah kunjungan pasien dan jumlah obat perpasien baik pada pasien DM tanpa komplikasi dan komplikasi. Kami juga menemukan bahwa persentase obat non DM lebih tinggi dibandingkan dengan obat DM. Secara statistik, jumlah obat DM dan non DM tidak berbeda secara signifikan antara sebelum dan setelah JKN (P>0,05). Rata-rata skor HRQoL pada era JKN lebih besar dari 80. Skor ini menunjukkan bahwa pasien memiliki kualitas hidup yang baik. Berdasarkan analisa statistik, kualitas hidup pasien berbeda berdasarkan jenis kelamin dan usia. Secara keseluruhan dapat disimpulkan bahwa terdapat perbedaan jumlah obat dan profil pengobatan setelah pelaksanaan JKN dan pasien memiliki kualitas hidup yang baik pada era JKN baik.
Frekuensi Genotip dan Alel Gena Sulfonylurea Receptor-1 (sur1) pada Subjek Diabetes Melitus Tipe 2 Suku Jawa YUNITA LINAWATI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 9 No 2 (2011): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (523.716 KB)

Abstract

Type 2 diabetes is a metabolic disorder that results from insulin secretion disorder, insulin action or both. SUR1 gene is part of KATP channel in the pancreatic β-cell that plays an essential role related with cell membrane depolarization and glucose-induced insulin secretion. The polymorphism p.R1273R of SUR1 gene, causes KATP channel failed to give feedback to metabolic activation, failed of closing KATP channel, reduces insulin secretion, impaired glucose tolerance, and causes type 2 diabetes. This is case-control study using 80 subjects consist of 40 subjects with type 2 diabetes as case and 40 subjects of non diabetes as control. The SUR1 gene p.R1273R polymorphism genotyping were detected by PCRRFLP. Data were statistically analyzed by t-test, Chi-Square. The genotype frequency distribution of p.R1273R SUR1 gene in type 2 diabetes subjects were 90% of GG genotype and 10% of AG genotype. In non diabetes subjects, GG genotype was 87,5% and AG genotype was 12.5%. In type 2 diabetes and non diabetes subjects the AA genotype was not observed. The allele frequency distribution in type 2 diabetes subjects G allele was 95% and A allele was 5%, in non diabetes subjects G allele was 93.75% and A allele was 6.25%. All the genotype and allele frequency distributions in type 2 diabetes and non diabetes subjects were not statistically significant (p = .723 genotype frequency; p = 0.732 allel frequency).
PENGARUH PERTUMBUHAN MIKROBA TERHADAP MUTU KECAP SELAMA PENYIMPANAN (The influence of growth of microbes on soy sauce quality during storage) Henky Isnawan Hendritomo
JURNAL ILMU KEFARMASIAN INDONESIA Vol 1 No 2 (2003): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (931.95 KB)

Abstract

This investigation conducted was to study the influence of growth of microbes on soy sauce quality during storage. The time of storage was as follows 1, 90 and 180 days. The determinations consisted of sucrose, protein, and sodium chloride content and total microbes such as molds and bacteria. The result showed that the sucrose content was 67,8% and protein content was 3,07%. After 6 months storage the sucrose and protein content decreased respectively from 67.8% to 58,8% and from 3.07% to 2,36%. The quantity of bacteria and molds increased respectively from 2100 to 3700 colony/ml and from 400 to 6100 colony/ml.
Aktivitas Ekstrak Buah Adas (Foeniculum Vulgare Mill.) terhadap Uterin Tikus Wistar Betina yang Belum Dewasa Kurnia Agustini; Dwi Riani Wulandari; Lestari Rahayu
JURNAL ILMU KEFARMASIAN INDONESIA Vol 15 No 2 (2017): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1792.352 KB) | DOI: 10.35814/jifi.v15i2.515

Abstract

Fennel fruit (Foeniculum vulgare Mill.) is one of traditional plant medicine known having effects as anti-infl ammatory, analgesic and antioxidant. It also has been reputed to increase milk secretion, promote menstruation, facilitate birth, alleviates the symptoms of the male climacteric andincrease libido. Fennel fruit contains mainly with essential oils, such as anethole. It also contains lignan and flavonoids that are predicted having an estrogen-like eff ect or as phytoestrogen. Phytoestrogen is weak agonists for estrogen and can elicit statistic signifi cantly increases in uterine wet weight, at definite dose, in the uterothrophic bioassay. It is known that estrogen has eff ect on woman’s sexual organ, such as proliferation of uterine, mammary and ovary. The aim of this research was to investigate the estrogenic eff ect of fennel fruit’s ethanolic extract in immature, 19 days old, Wistar female rats. These models represent the climacteric/menopause phase, where estrogen level is very low because in this age, estrogen not yet produced by ovary. The testing animals were divided into fi ve groups, namely normal group, estradiol control group and three level doses of fennel extract (30 mg/200 g BW; 60 mg/200 g BW and 120 mg/200 g BW). The result indicated that start on 60 mg/200 g BW, fennel extract signifi cantly (α=0.05) increased wet weight of uterine. Fennel extract also lengthen the uterine and increased proliferation of uterine, such as uterine diameters, endometrium diameters and uterine thickness on dose 60mg/200gBW and 120mg/200gBW. Analysis of vaginal smear showed vaginal lubrication eff ect, surprisingly start on 60mg/200BW could induce estrous cycle.
Analisis Korelasi antara Efek Proliferasi Limfosit dengan Kandungan Fenolik dan Flavonoid Subfraksi Etil Asetat Myrmecodia tuberosa (Non Jack) Bl. secara In Vitro pada Mencit BALB/C AKHMAD KHUMAIDI; TRIANA HERTIANI; EDIATI SASMITO
JURNAL ILMU KEFARMASIAN INDONESIA Vol 13 No 1 (2015): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (979.102 KB)

Abstract

Ethyl acetate fraction of Myrmecodia tuberosa (non Jack) Bl. expressed potential immunomodulatory effect in preliminary study. This study was aimed to determine the stimulation index of each subfraction towards lymphocyte of BALB/C mice by in vitro technique and to explore the activityof lymphocyte proliferation correlated to total phenolic contents. lymphocyte proliferation assay was performed by MTT. Determination of total flavanoid content was done by a colorimetric method while the total phenolic was tested by the Folin-Ciocalteu method. The result showed stimulation index profile was positively correlated with the total flavanoid content( R2 = 0,606) while weak correlation was observed on the total phenolic content (R2 = 0,167).
Pengembangan Metode Analisis Amoksisilin yang Selektif dan Tidak Dipengaruhi Keberadaan Produk Degradasinya REHANA REHANA; HANIF HAFIIDH SETYO NUGROHO; VITIS VINI FERA RATNA UTAMI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 12 No 2 (2014): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1796.484 KB)

Abstract

Assay of amoxycillin level in suspension form using spectrophotometry method at maximum wavelength around 291 nm is predicted to provide accurate and selective result because it is not interferred with its degradation products. This research aimed to obtain the predicted result. This research employed laboratory experimental method which included the process of measuring of maximum wavelength and operating time measurement, making of standard curve by measuring absorbance of amoxycillin standard solution at 40, 50, 80, 100 and 120 ppm at 290 nm and testing the selectivity and accuracy. Selectivity test was done by comparing UV spectrum and maximum absorbance of 1 mg/mL amoxycillin standard solution and 125 mg/5 mL amoxycillin suspension immediately after reconstitution with the one that was stored 9 days. Accuracy test was conducted by standard addition method using 1 mL amoxycillin suspension that was stored 9 days added by 1 mL 6260 ppm amoxycillin standard solution. Assay of amoxycillin on amoxycillin suspension by UV spectrophotometry at 290 nm using NaOH 0,1 N as solvent gave selective and accurate result with 97,36% recovery and it is not interfered with by its degradation product.
Aktivitas Antioksidan dan Toksisitas Senyawa Bioaktif dari Ekstrak Rumput Laut Hijau Ulva reticulata Forsskal Swasono R. Tamat; Thamrin Wikanta; Lina S. Maulina
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 1 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (952.677 KB)

Abstract

Research on the antioxidative activity and toxicity of the bioactive substance of the green seaweed Ulva reticulata Forsskal extract had been carried out. The bioactive substance of the green seaweed Ulva reticulata Forsskal was extracted using methanol. The phytochemistry test on the methanol extract showed that the extract contained triterpenoid compound. The methanol extract was then partitioned using n-hexane-water (1:1) and chloroform-water (1:1). Each of the extract was then dried using freeze dryer. The antioxidative activity test of each fraction against free radical 1,1-diphenyl-2-picrilhydrazil (DPPH) showed that the water extract has the highest activity with IC 30 of 365,95 ug/ml. The toxicity test of each fraction against brine shrimp Artemia salina (Brine Shrimp Lethality Test, BSLT) showed that the chloroform extract showed the highest activity with LCs of 250,67 ug/ml. The water extract was then fractionated through silica column chromatography. The activity test of each fraction against DPPH and BSLT showed that fraction 1 has the highest activity with LCs of 100 ug/ml and ICs of 270,31ug/ ml. Identification using gas chromatography – mass spectrometric method showed that the antioxidative substance presence in the active fraction was probably nonyl phenol (C, H2,0).

Page 31 of 73 | Total Record : 721

 29   30   31   32   33 

Filter by Year

2003 2025


Reset
Filter By Issues
All Issue Vol 23 No 2 (2025): JIFI Vol. 23 No. 2 (2025): JIFI Vol 23 No 1 (2025): JIFI Vol. 23 No. 1 (2025): JIFI Vol 22 No 2 (2024): JIFI Vol 22 No 1 (2024): JIFI Vol 21 No 2 (2023): JIFI Vol 21 No 1 (2023): JIFI Vol 20 No 2 (2022): JIFI Vol 20 No 1 (2022): JIFI Vol 19 No 2 (2021): JIFI Vol 19 No 1 (2021): JIFI Vol 18 No 2 (2020): JIFI Vol. 18 No. 2 (2020): JIFI Vol 18 No 1 (2020): JIFI Vol 17 No 2 (2019): JIFI Vol 17 No 1 (2019): JIFI Vol 16 No 2 (2018): JIFI Vol 16 No 1 (2018): JIFI Vol 15 No 2 (2017): JIFI Vol 15 No 1 (2017): JIFI Vol 14 No 2 (2016): JIFI Vol 14 No 1 (2016): JIFI Vol 13 No 2 (2015): JIFI Vol 13 No 1 (2015): JIFI Vol 12 No 2 (2014): JIFI Vol 12 No 1 (2014): JIFI Vol 11 No 2 (2013): JIFI Vol 11 No 1 (2013): JIFI Vol 10 No 2 (2012): JIFI Vol 10 No 1 (2012): JIFI Vol 9 No 2 (2011): JIFI Vol 9 No 1 (2011): JIFI Vol 8 No 2 (2010): JIFI Vol 8 No 1 (2010): JIFI Vol 7 No 2 (2009): JIFI Vol 7 No 1 (2009): JIFI Vol 6 No 2 (2008): JIFI Vol 6 No 1 (2008): JIFI Vol 5 No 2 (2007): JIFI Vol 5 No 1 (2007): JIFI Vol 4 No 2 (2006): JIFI Vol 4 No 1 (2006): JIFI Vol 3 No 2 (2005): JIFI Vol 3 No 1 (2005): JIFI Vol 2 No 2 (2004): JIFI Vol 2 No 1 (2004): JIFI Vol 1 No 2 (2003): JIFI Vol 1 No 1 (2003): JIFI More Issue