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Jurnal Biomedika dan Kesehatan
Published by Universitas Trisakti
ISSN : 2621539x     EISSN : 26215470     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Jurnal Biomedika dan Kesehatan is an official publication of Faculty of Medicine Trisakti University. Jurnal Biomedika dan Kesehatan is a third-monthly medical journal that publishes new research findings on a wide variety of topics of importance to biomedical science and clinical practice. Jurnal Biomedika dan Kesehatan online contains both the current issue and an online archive that can be accessed through browsing, advanced searching, or collections by disease or topic.
Arjuna Subject : -
Articles 14 Documents
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Search results for , issue "Vol 6 No 3 (2023)" : 14 Documents clear
Hubungan Parameter Laboratorium dengan Derajat Klinis COVID-19 pada Kehamilan Nirmalasari, Rully Ayu; Surjadi, Lily Marliany; Maharani, Laksmi; Lisnawati, Yuyun; Mangun, Dhea
Jurnal Biomedika dan Kesehatan Vol 6 No 3 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.291-299

Abstract

Background Pregnant women were one of the most susceptible groups because they are vulnerable to respiratory infection. They may get more severe symptoms due to their physiological changes during pregnancy including the immunological response. This study was performed to find whether there is an association between laboratory parameters (Hb, leukocytes, platelet, neutrophils, lymphocyte, monocyte, NLR, PLR and CRP) and the severity of Covid-19 infection in pregnant women. Methods This study is a retrospective cohort study using secondary data from patient’s medical records at Persahabatan General Hospital, Jakarta from March to June 2021. Results Pregnancy cases with COVID-19 in this study were in the mean of 29 year age. Most of them are in the third trimester of pregnancy. 80.5% from 67 patients have no- mild symptom while 19.5% have moderate to severe symptom. There are no difference in vital sign nor oxygen saturation at first admission. Lower level was found in the parameter of leukocyte, lymphocyte and monocyte.  Neutrophil, neutrophil-to-lymphocyte ratio and C-reactive Protein increase as the degree of severity increase.  The mean neutrophil in pregnant women with moderate to severe COVID-19 symptom was 80.49±7.47 while median NLR value was of 6.76 (2.73-18.71) . Conclusions Neutrophil, neutrophil-to-lymphocyte ratio and C-reactive Protein has associate significantly to severity symtomps of COVID-19 in pregnancy.
Metachronous Multifocal Osteosarcoma Setelah 5 bulan terapi: Metastasis atau Lesi Primer Lain? Astien, Astien; Hairunisa, Nany; Abikusno, Nugroho; Abikusno, Revalita; Agil, Nadifa; T, Febrina
Jurnal Biomedika dan Kesehatan Vol 6 No 3 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.347-353

Abstract

Multifocal osteosarcoma is a rare form osteosarcoma. It is diagnosed by having two or more lesions without any visceral damage. Osteosarcoma is characterized by having concurrent numerous lesions; the synchronous type,  and metachronous type are characterized by non-concurrent multiple lesions form. This case reports a boy 4 years old with a left femur osteosarcoma; histopathologically confirmed as chondroblastic osteosarcoma. After 5 months of chemotherapy, a new lesion was found at the left side of the cruris and pedis bones that were multiple, destructive, permeative, and exhibiting periosteal reaction. No visceral damage was found.  In this case, the patient had a primary lesion and new non-concurrently lesions and no visceral damage, as conclusion was diagnosed as metachronous multifocal osteosarcoma that had never been reported in Indonesia.
Penyakit Ginjal Kronis : apakah pola makan berbasis nabati efektif? Kurniawan, Wawan; Hairunisa, Nany; Amarendra, Gerie
Jurnal Biomedika dan Kesehatan Vol 6 No 3 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.373-382

Abstract

Chronic kidney disease (CKD) is a global problem whose number of sufferers is increasing. Various methods have been widely used to prevent worsening of kidney function. In addition to controlling causative factors, diet planning also plays a role in improving kidney function. Confining protein utilization has long been a foundation of wholesome treatment for patients with CKD. In any case, the suggested sum of dietary protein admissions may change between consensus. A vegan who eats less that's exceptionally low in protein has appeared to diminish the chance of kidney failure in patients with progressed CKD. These findings indicate that protein sources can also influence the improvement of kidney function. Dietary medications play a good part in the management of CKD and avoiding or postponing kidney replacement therapy. The study proposes that a plant-dominant low-protein diet (PLADO) of 0.6–0.8 g/kg/day composed of >50% plant-based sources, managed by nutritionists prepared in non-dialysis CKD care, is promising and reliable with the exactness diet. Plant-based Very low-protein diets may inhibit decreased eGFR (estimated glomerular filtration rate) and the need for renal replacement therapy. This literature review aims to find evidence about the effectiveness of plant-based diets in treating cases of chronic kidney failure.
JN.1 COVID-19: Variant of interest Amalia, Husnun; Mashabi, Yasmine
Jurnal Biomedika dan Kesehatan Vol 6 No 3 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.261-263

Abstract

Corona Virus Disease-19 (COVID-19) is an acute respiratory syndrome caused by the Coronavirus 2 (SARS-CoV-2) virus. WHO groups the SARS-CoV-2 virus into two categories, namely a variant of interest (VOI) and a variant of concern (VOC). The VOI category is given if there is a new mutation with predictable phenotypic implications and must be fulfilled by one mutation that causes local transmission or causes multiple clusters or is detected in several countries. In September 2023, a new variant of COVID-19 was detected in the United States, namely JN.1 as VOI. This variant is a variation of the BA.2.86 variant with the only difference being the mutation of 1 spike protein, namely the addition of the L455S protein in the JN.1 variant. This variant has the potential to evade the immune system. Globally, there has been a rapid increase in the number of sufferers, especially in 3 WHO regions, namely America (AMR), West Pacific (WPR) and Europe (EUR). However, the effectiveness of the monovalent vaccine against this variant can still protect sufferers. Several studies show that the risk of hospitalization is low in the case of elderly and young patients.

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