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Jurnal Respirasi (JR)
Published by Universitas Airlangga
ISSN : 24070831     EISSN : 26218372     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in Indonesian.
Arjuna Subject : -
Articles 321 Documents
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Pregnancy-Related Disorders and Intrauterine Impaired Lung Development Zulhadji, Harry Agustio; Yunus, Faisal; Rasmin, Menaldi; Saroyo, Yudianto Budi; Amien, Bagus Radityo
Jurnal Respirasi Vol. 10 No. 2 (2024): May 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.2.2024.178-185

Abstract

Various pregnancy-related disorders are known to affect fetal lung development negatively. During pregnancy, chronic nutrition and/or oxygen limitation is known to impede lung maturation and induce airway and lung abnormalities. Structural abnormalities and reduced lung function may be evident immediately after birth, persist, or develop with age. The expansion of the fetal lung, fetal breath movements, fetal lung growth, alveolarization, blood-air barrier, extracellular matrix (ECM), airways, surfactant system, and lung immune function are all affected by nutritional limitations during pregnancy. Gestational hypoxia disrupts fetal lung development, which manifests as morphological and functional pulmonary abnormalities. Additionally, intrauterine growth restriction (IUGR), preeclampsia (PE), exposure to air pollution, and smoking are known to interfere with embryonic lung development. Birth defects, such as bronchopulmonary dysplasia, as well as chronic obstructive pulmonary disease (COPD), can be caused by abnormalities in pregnancy. Adequate nutrition, avoidance of smoking, and watchful monitoring and intervention during pregnancy should be promoted to prevent chronic lung disease of the newborn, child, and adult.
Comparison of Anxiety Levels in MDR-TB Patients with Individual and Short-term Regimens at Dr. Soebandi Regional General Hospital, Jember, Indonesia Widodo, Muhammad Rifqy Alvy; Astuti, Ida Srisurani Wiji; Kusumastuti, Inke; Raharjo, Angga Mardro; Supangat, Supangat; Tyaswati, Justina Evy; Zulkifli, Noor Fadzilah binti
Jurnal Respirasi Vol. 10 No. 2 (2024): May 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.2.2024.107-113

Abstract

Introduction: Multidrug-resistant tuberculosis (MDR-TB) is a form of TB that shows resistance to both isoniazid and rifampicin. Globally, the number of new MRD-TB cases has continued to rise since 2020. Indonesia is positioned among the top ten countries with the highest incidence of MDR-TB worldwide. Specifically, Jember ranked second in the number of MDR-TB cases in East Java. This study aimed to assess the comparison between the administration of individual MDR-TB regimens and short-term regimens concerning anxiety levels in MDR-TB patients at Dr. Soebandi Regional General Hospital, Jember. Methods: This was an analytical observational study with a cross-sectional design. It was conducted at Dr. Soebandi Regional General Hospital, Jember, using interviews and medical record data from August to September 2023. The sample size was 69 participants, who were obtained through consecutive sampling. Analysis was performed using the Statistical Package for the Social Sciences (SPSS) and the Chi-Square test for group comparisons. Results: This study found that 64% of subjects received individual regimens. In the individual regimen group, 80% of subjects reported anxiety. Among the short-term regimen group, 60% of subjects showed no anxiety. The significance value of this study was 0.007 in the Chi-Square test for group differences. Conclusion:  There was a difference in anxiety levels between individual and short-term regimens among MDR-TB patients at Dr. Soebandi Regional General Hospital, Jember. Patients with anxiety were more common in individual regimens compared to short-term regimens.
Determining Factors for Smoking Habits and FeNO Levels in Male College Student Smokers Tadjoedin, Irfan Hasyim; Wibowo, Adityo; Damayanti, Triya
Jurnal Respirasi Vol. 10 No. 2 (2024): May 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.2.2024.130-136

Abstract

Introduction: Smoking remains a pervasive and persistent health issue in Indonesia. Numerous studies have explored the impact of smoking and fractional exhaled nitric oxide (FeNO) levels on college students. However, none have been conducted in Indonesia. With a substantial number of smokers and teenage smokers in the country, there is a critical need to understand the implications of smoking. This study aimed to enhance the comprehension of the motivations behind smoking habits and, consequently, to devise more effective smoking cessation programs. It specifically sought to elucidate the relationship between smoking habits and exhaled nitric oxide (NO) levels among college students and to explore the reasons why students smoke. Methods: This study employed analytical and descriptive cross-sectional approaches. We interviewed 124 participants, 30 of whom were randomly selected for FeNO-level testing. Results: The mean age of the subjects was 20.1 ± 1.54 years. Of these, 48 (38.7%) were enrolled in science and technology programs and 76 (61.3%) in social sciences. The Brinkman index predominantly indicated a mild level of smoking (96.8%), with a moderate level observed in 3.2% of the subjects. The median FeNO level was 12 ppb. According to the Horn questionnaire, the most cited reasons for smoking were pleasure (71%), followed by stress relief (66.1%) and stimulation (38.7%). No significant correlation was found between the Brinkman index and FeNO levels. Conclusion: The primary factors influencing smoking habits among the subjects were stress relief and the pleasure derived from smoking. No correlation was observed between smoking habits and exhaled NO levels.
The Dynamic of Smoking Behavior through the Course of Tuberculosis Illness: A Hospital-Based Study in Medan, Indonesia Safira, Nanda; Wichaidit, Wit; Chongsuvivatwong, Virasakdi
Jurnal Respirasi Vol. 10 No. 2 (2024): May 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.2.2024.114-119

Abstract

Introduction: Smoking is associated with the prognosis of tuberculosis (TB). The diagnosis of TB in patients who smoke or recently quit smoking can be a pivotal moment that motivates them to continue quitting smoking. However, there is a paucity of information on changes in smoking status among TB patients through the course of the disease. This study presented self-report smoking status during the pre-symptomatic, post-symptomatic, intensive treatment, and continuation treatment phases among TB patients receiving treatment. Methods: This was a cross-sectional study conducted at four hospitals in Medan, Indonesia, from December 2019 to February 2020. For at least one month, healthcare workers invited TB patients who had received treatment at the hospitals' TB-Directly Observed Treatment Shortcourse (DOTS) clinics to participate in this study. Trained enumerators collected the data through face-to-face interviews, in which the patients self-reported information on their smoking status at various phases. Results: Of 285 patients who met the inclusion criteria, 277 gave their consent (97% participation), of whom 146 never smoked in their lifetime. Among 131 ever smokers, 88 (67%) had quit smoking before or during the pre-diagnosis phase, 65 (51.6%) of whom remained quitters throughout the course of the disease. Thirty-eight patients continued to smoke after symptom onset, and more than half of them had stopped smoking by the continuation phase of treatment. Conclusion: Smoking cessation was relatively common after the appearance of TB symptoms and after diagnosis. However, some patients subsequently relapsed, while others were unable to quit smoking. Social desirability could have influenced the responses and should be considered in interpreting the study findings.
The Effect of Anemia on Prognostic in Non-Small Cell Lung Cancer Patients Receiving Platinum-Based Chemotherapy Kartikasari, Ulfah; Pratiwi, Suryanti Dwi; Astuti, Tri Wahju; Setijowati, Nanik
Jurnal Respirasi Vol. 10 No. 2 (2024): May 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.2.2024.120-129

Abstract

Introduction: Lung cancer has the highest incidence and mortality rate, which contributes to approximately 2.2 million cancer cases (11.4%) of total cancers worldwide. More than 70% of lung cancer cases present in the late, non-operable stage. Anemia is one of the conditions that could precipitate cancers and affect the patient's clinical presentation, including tissue oxygenation, organ function, and quality of life. It could also increase the risk of bleeding, post-operative mortality, and iron absorption rate in the case of ineffective erythropoiesis. All of these could affect the prognostic factor of the cancer. This study aimed to evaluate the effect of the severity of anemia on overall survival (OS) and progression-free survival (PFS) in non-small cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy. Methods: This was a retrospective cohort study involving 80 subjects of NSCLC patients treated with platinum-based chemotherapy from January 2018 to December 2020. Subjects were divided into two groups (39 patients in the normal group and 41 patients in the anemia group). Results: The mean pre-treatment hemoglobin (Hb) was 10.55 ± 1.25 g/dL in NSCLC patients with anemia. The bone metastasis, OS, and PFS values of the normal and anemia groups were significant (p = 0.008; p = 0.002; p = 0.27). Anemia was significantly related to OS (r = 0.146, p = 0.000) and PFS (r = 0.264, p = 0.000) in NSCLC patients treated with platinum-based chemotherapy. Conclusion: Higher severity of anemia can reduce OS and PFS in NSCLC patients treated with platinum-based chemotherapy.
Front Matter Vol 10 No 1, 2024 Matter, Front
Jurnal Respirasi Vol. 10 No. 1 (2024): January 2024
Publisher : Faculty of Medicine Universitas Airlangga

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Abstract

Back Matter Vol 10 No 1, 2024 Matter, Back
Jurnal Respirasi Vol. 10 No. 1 (2024): January 2024
Publisher : Faculty of Medicine Universitas Airlangga

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Abstract

Epididymo-Orchitis: A Rare Manifestation of Tuberculosis Infection Pattiselanno, Yoshua Ariel; Pattiselanno, Laurenz Lolly; Leo, Benedreky; Hadi, Choirul; Angel, Sharon Hanmy
Jurnal Respirasi Vol. 10 No. 2 (2024): May 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.2.2024.155-160

Abstract

Introduction: Tuberculosis (TB) is caused by Mycobacterium tuberculosis (MTB) and now represents a significant global health concern, with an estimated 10 million people infected with TB in 2022, equivalent to 133 incident cases per 100,000 population. Indonesia faces a substantial burden. The World Health Organization (WHO) estimates 969,000 TB cases, with 717,941 confirmed cases reported. Extrapulmonary TB, contributing to 15% of TB cases, affects various areas such as bones, pleura, lymph nodes, genitourinary system, peritoneum, and meninges. Tuberculous epididymo-orchitis, a rare type of extrapulmonary TB, is characterized by MTB infection in the epididymis or testis. Case: A 31-year-old male was presented to the Emergency Department of Budi Rahayu General Hospital, Pekalongan, with a fever, bitter taste, body aches, and cough. Initially hospitalized for five days and discharged upon improvement of symptoms, the patient returned with fatigue, cough, and black stools. After being admitted under internist and pulmonary specialist care due to a suspected left lung TB apical lesion, biomolecular testing (GeneXpert) was performed. Consultation with a urologist revealed scrotal pain, prompting further tests including urine acid-fast bacilli (AFB) examination, testicular ultrasound, and aspiration culture. The patient was diagnosed with TB epididymo-orchitis and treated with a Category 1 TB regimen. Conclusion: TB epididymo-orchitis is a rare case requiring thorough diagnostic evaluation encompassing anamnesis, physical examination, and diagnostic procedures. Early detection and appropriate management are vital in combating this challenging disease.
Neutrophil-Lymphocyte Ratio and Nutritional Status as Parameters of Sputum Conversion in MDR-TB Before & After 3 Months of Anti-TB Treatment Regina, Putri Maria; Silaen , Johan Christian; Sembiring, Susi
Jurnal Respirasi Vol. 10 No. 2 (2024): May 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.2.2024.137-142

Abstract

Introduction: The prolonged duration of tuberculosis (TB) treatment has led to an increase in non-compliance among TB patients undergoing anti-TB treatment, consequently leading to treatment failure and drug resistance, notably multidrug-resistant TB (MDR-TB). Individuals with poor nutritional status may elevate the risk of delayed sputum conversion in MDR-TB patients. The neutrophil-lymphocyte ratio (NLR) represents a laboratory parameter with potential as a prognostic indicator in patients suspected of TB infection. Methods: This was an analytical study with a cross-sectional design. The sample was drawn from the medical records of MDR-TB patients at Haji Adam Malik General Hospital, Medan, from October 2022 to March 2023 resulting in a total of 83 samples. Data analysis was performed using Statistical Package for the Social Sciences (SPSS) version 25 software, and bivariate analysis was conducted using paired t-test. Results: Out of 83 MDR-TB patients, 50 (60.2%) were male. Based on nutritional status before three months of anti-TB treatment, the most common nutritional status was normal with 22 individuals (26.5%) and severely underweight with 36 individuals (43.4%). Following three months of anti-TB treatment, the majority had normal, totaling 39 individuals (47%). A total of 67 individuals (80.7%) experienced sputum conversion. The results indicated a significant difference between NLR before and after three months of anti-TB treatment (p = 0.000), as well as a significant difference between nutritional status before and after three months of anti-TB treatment (p = 0.012) at Haji Adam Malik General Hospital, Medan. Conclusion: Significant differences were observed in NLR and nutritional status before and after three months of anti-TB treatment.
Front Matter Vol 10 No 2, 2024 Matter, Front
Jurnal Respirasi Vol. 10 No. 2 (2024): May 2024
Publisher : Faculty of Medicine Universitas Airlangga

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Page 26 of 33 | Total Record : 321

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