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INDONESIA
Medical and Health Science Journal
Published by Universitas Nahdlatul Ulama Surabaya
ISSN : 25497588     EISSN : 25497596     DOI : https://doi.org/10.33086/mhsj
Core Subject : Health, Social,
Health Professions Social Sciences
Medical and Health Science (MHSJ) published peer-reviewed original articles research, case report or article review. This journal is published twice (February and August) by Faculty of Medicine Universitas Nahdlatul Ulama Surabaya.
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Articles 192 Documents
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The Effect of High Dose Vitamin C (ascorbic acid) on Proinflammatory Cytokines in COVID-19 MD Ayu Mira Cyntia Dewi -
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 1 (2021): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i1.1884

Abstract

Background: COVID-19 is a new pandemic that has claimed many lives in many countries. This pandemic was caused by the SARSCoV2. Until now, there is no specific antiviral drug or vaccine against Covid-19 for potential therapy in humans. This virus can cause cytokine storms which can worsen symptoms in sufferers due to an imbalance between increased oxidant production and available antioxidants. Vitamin C is an important antioxidant that protects the body from various bad effects of free radicals. At high concentrations vitamin C plays an important role in immunomodulation. This study was conducted to determine the effect of high doses of vitamin C on levels of pro-inflammatory cytokines in Covid-19. Method: This research type is literature study. The population in this study were journals about Covid-19, vitamin C, antioxidants and free radicals, inflammatory reactions due to viral infections with samples taken from indexed journals published from 2015 to 2020. There are also clinical trials of high doses of vitamin C against inflammation in Covid-19 from these journals. Results: The results of the study in a clinical trial conducted on 54 patients enrolled in 3 hospitals given a 1: 1 ratio for high-dose intravenous vitamin C (HDIVC) or placebo administration. The HDIVC group received 12 g of vitamin C / 50 ml every 12 hours for 7 days at a rate of 12 ml / hour, and the placebo group received bacteriostatic water for injection in the same way. HDIVC administration showed a reduction in inflammatory markers compared to placebo. Conclusion: The conclusion of this study shows that high doses of vitamin C play a role in reducing levels of proinflammatory cytokines.
The Effect Of Giving Honey on The Process of Wound Healing in Burned Patients Intan Pramesty
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 1 (2021): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i1.1910

Abstract

Backgroud: Burns are one of the most dangerous injuries and the main cause of disability to death. Burns can be interpreted as one of the serious problems in society and are recorded to cause around 265,000 deaths each year. Honey can maintain the wound condition to keep it moist and in high viscosity to prevent infection. Method: This study was conducted to determine the effect of honey on the wound healing process in burn patients. This study uses a literature review method. The population in this study is a journal with a background in the health sector with 10 international journals on burns with the qualifications of 9 SCIMAGO indexed journals and 1 SINTA indexed journal published from 2015 to 2020. Results: Burns that treated in the form of pure honey can generate good results and heal in an average of 20 days. The healing process will be better, if the wound given a mixture of other ingredients which also have a low acidity such as garlic, chitosan and beeswax and olive oil. Honey has antimicrobial properties and a low pH level. The microbe most sensitive to honey is Staphylococcus aureus. Conclusion: The conclusion from this study, honey can be used as an alternative treatment for burns.
The Role Of Tea Tree Oil as A Skin Antimicrobial : A Literature Study Dian Ardiana
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 1 (2021): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i1.1921

Abstract

Background: Skin disease due to microorganism infection are still widely found in community. The infections can be caused by bacteria, viruses, fungi, and parasite. Tea tree oil often used as a herbal medicine in the treatment of skin diseases due to microorganisms. This literature study is conducted to review the role of tea tree oil as an antimicrobial in skin infections. Method: Fifteen indexed journals published from 2015 to 2020 about tea tree oil and skin infections, were included. From 15 journals, 9 journals discuss antibacterial activity of tea tree oil, 2 journals discuss antiviral activity, 9 journals discuss antifungal activity, and 1 journal discusses antiparasitic activity. All journals state that tea tree oil has an antimicrobial effect on microorganisms that cause skin infections. Result: From 9 journals, it was found that A. baumanni, P. aeruginosa, and C. acnes were the most sensitive bacteria to tea tree oil in terms of MIC and S. epidermidis was the most sensitive bacteria, seen from their inhibition zone. Eight journals state variations with significant differences in the activity of tea tree oil as an anti-fungal. Tea tree oil has stronger antibacterial activity than antifungal activity. It also has antiviral activity against HSV and antiparasitic on S. scabiei. Conclusion: The conclusion of this study is that tea tree oil has antimicrobial activity against microorganisms that cause skin disease, including bacteria, viruses, fungi, and parasite.  
COMPARISON OF LAPAROSCOPIC AND ABDOMINAL SACROCOLPOPEXY FOR POST HYSTERECTOMY VAGINAL VAULT PROLAPSE REPAIR: META ANALYSIS Amani, Fariska Zata; Denas, Azami; Paraton, Hari; Hardianto, Gatut; Mardiyan K, Eighty; Hartono S, Tri
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 2 (2021): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i2.1929

Abstract

Objective: Comparing the clinical outcomes of laparoscopic and abdominal sacrocolpopexy in vaginal vault prolapse post-hysterectomy’s patient. Method: Systematic search data is performed on medical database (PUBMED, Cochrane Database) using keyword:(1) vault prolapse [title] AND (2) laparoscopic[title] AND sacrocolpopexy[title]. Inclusion criteria:(1) randomized controlled trial and observational studies, (2) women with vaginal vault prolapse post hysterectomy, (3) intervention studied: laparoscopic (LSC) and abdominal sacrocolpopexy (ASC), (4) the entire fully accessible papers can be accessed and data can be accurately analyzed. Comparison about clinical outcomes of LSC and ASC was performed using narrative analysis and meta-analysis (RevMan). Results: Three studies compared clinical outcomes of LSC and ASC with a total of 243 samples (118 in LSC and 125 in ASC group). There was no significant difference in the incidence of complications between LSC and ASC (OR 1.10;95%CI 0.58-2.08). LSC was associated with less blood loss (MD 111.64 mL,95%CI-166.13 - -57.15 mL) and shorter length of hospital stay (MD -1.82 days;95%CI -2.52- -1.12 days) but requires a longer operating time (MD 22.82 minutes,95%CI 0.43-45.22 minutes). There was no statistically significant difference to anatomical outcomes (measurement of point C on POP-Q), subjective outcomes measured by PGI-I and reoperation numbers (repeat surgical interventions) for prolapse recurrence between LSC and ASC groups after one year of follow-up. Conclusions: LSC showed similar anatomic results compared to ASC with less blood loss and shorter length of hospital stay in management patient with vaginal vault prolapse.
AN OVERVIEW SELF-EFFICACY AND SELF-ACCEPTANCE IN TUBERCULOSIS SUFFERERS Setiyowati, Eppy; Hardiyanti, Hardiyanti; Setiawan, Ferry Agus; Susilo, Priyo
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 2 (2021): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i2.2160

Abstract

Background: Tuberculosis is still a major health problem in Indonesia, especially in the working area of the East Health Center in Surabaya, the long treatment of tuberculosis causes sufferers to have low self-efficacy and poor self-acceptance. Objective: This study aims to analyze the relationship between self-efficacy and the self-acceptance of patients with Tb. Method: The design research is an analytic study with a cross-sectional approach. The study population of 46 patients with active treatment for the last 3 months in the work area of the community Health Center in Surabaya by 46 patients. Results: A sample of 41 respondents taken by simple random sampling technique. The independent variable is self-efficacy, the dependent variable is self-acceptance. The instrument uses a questionnaire. Data analysis used the Chi-Square test with significance value α = 0.05. The results showed that of 41 respondents the majority (57.3%) had low self-efficacy, and the majority (57.3%) had poor self-acceptance. Chi-Square statistical test results obtained value ρ = 0.008 < a = 0.05 shows there is a relationship of self-efficacy with self-acceptance of patients with TB in the work area of the East Perak Health Center in Surabaya. Conclusions: Conclusions of the study that the lower the self-efficacy in patients with Tb the worse the self-acceptance and vice versa. Patients with TB should further improve their efficacy by always obeying health workers' advice and treatment regularly. The role of nurses in improving self-efficacy by providing education to sufferers and families, working together to care more, and motivate patients so that treatment success.
IMPLEMENTATION OF OCCUPATIONAL SAFETY AND HEALTH RISK MANAGEMENT IN ISLAMIC HOSPITAL SURABAYA A. YANI Firmansyah, Muhammad Huda; Moch. Sahri; Setianto, Budhi
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 2 (2021): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i2.2179

Abstract

Background: Risk management is a preventive effort for a company, especially those engaged in the service sector, which is very prone to errors and complaints. For this reason, it is necessary to map the risks that occur in accordance with the work unit in it which is expected to minimize the number of accidents or errors in both patients, visitors and employees in the hospital. In the 2019 patient safety incident report data at the Surabaya A. Yani Islamic Hospital, it was found that there were incidents which included near miss 93%, not injured 4%, unexpected events 3% and Sentinel 0%. The purpose of this study was to identify and identify the application of occupational safety and health risk management at the A. Yani Islamic Hospital in Surabaya. Methods: This thesis is a qualitative research with a case study method with the aim of fully describing the implementation of K3 risk management at Surabaya A. Yani Hospital based on observation, survey and documentation data on 37 units and hospital workplaces by identifying risks. , analyze and find risk control measures. Results: The results showed that the implementation of K3 risk management in the Islamic Hospital of Surabaya A. Yani based on the results of risk identification obtained as many as 25 risks in the graha building and the old building which were further analyzed by finding 15 moderate risks and 10 high risks. can be done is by repairing damaged infrastructure and improving the existing security system at the A. Yani Islamic Hospital in Surabaya. Conclusion: The conclusion in this study is the implementation of K3 risk management at the Islamic Hospital of Surabaya A. Yani based on the process of risk identification and risk analysis, there are 25 potential risks, of which there are 15 moderate risks and 10 high risks that can potentially cause accidents to employees, visitors and patients. In this case, control efforts are made to minimize the number of incidents and accidents.
CASE REPORT BLEPHAROCONJUNCTIVITIS AS MANIFESTATION OF STEVENSJOHNSON SYNDROME Saraswati Surya, Putu Ayu Adindhya; Sunariasih, Ni Nyoman
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 2 (2021): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i2.2189

Abstract

Background: Stevens Johnson syndrome (SJS) is a collection of acute and life threatening skin symptoms caused by an allergic drug reaction. SJS also attacks the other mucous membranes, one of which is the eye. SJS is a rare case. The initial complaint of SJS is the eruption on the skin in the form of redness followed by blisters and attacking other mucous membranes. The ocular manifestations of SJS are conjunctivitis, corneal erosion, corneal ulcers, and blepharitis. Methods: Treatment of SJS’s ocular manifestation is administration of drugs and surgical intervention. Administration of drugs that often done in the acute phase is antibiotic eye drops with steroids to prevent complications. Complications that can occur include symblepharon, districhiasis, and keratitis. This complication can cause a sharp decrease in vision. Results: This case report discusses a 68 year old male patient with blisters all over his body accompanied by swelling in both eyes, redness in both eyes, and difficult to open eyes. Patients with history of taking the new drug a month ago. No history of drug allergy. The patient suffered from hypertension, non-hemorrhagic stroke, and epilepsy with irregular treatment. Patient was performed a fluorescein test. In this case, the patient is given antibiotic ointment and artificial tears with steroids. In this case there were no complications. Conclusion: The ocular manifestations of SJS if handled quickly and properly can prevent long-term complications.
THE PROFILE AND PATIENT ACUTE HEPATITIS CHILDREN OUTPUT IN DR SOEBANDI JEMBER HOSPITAL Adita Rini, Ika Wahyu; Shodikin, M. Ali
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 2 (2021): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i2.2019

Abstract

Background: Indonesia is an endemic area for Hepatitis akut. District of Jember determines the status of extraordinary event Hepatitis akut at the end of 2019. The purpose of this study was the profile and patient acute hepatitis children output in dr Soebandi Jember Hospital in December 2019 until January 2020. Methods: This study was retrospective descriptive. The material was taken of the medical records Hepatitis akut patient at the pediatric departement of the dr. Soebandi Hospital in Jember. Results: In this study, patients most often occurred in male, age ranged between 7 – 14 years, and lived on the villages. The most common of clinical manifestation are anorexia, jaundice, fever, hepatomegaly, dark urine, vomiting and abdominal pain. The result of laboratory examination showed that Hepatitis acut patient had elevated of SGOT , SGPT, direct and total bilirubin. Conclusions: The combination of curcuma with SNMC (Stronger Neo-Minophagen C)  reductly significant SGOT and SGPT serum levels (p < 0,001).  
MAKING PREGNANCY A MISSED OPPORTUNITY FOR TREATMENT OF TUBERCULOSIS INFECTION : A SYSTEMATIC REVIEW Atmaja, Sardjana; Gumilar, Gulam
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 2 (2021): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i2.2081

Abstract

Background : Eleven million Americans, representing 4% of the U.S. general population, are estimated to have latent tuberculosis infection (LTBI). In countries with low TB incidence, immigrant from higher incidence countries form the major pool of infected individuals. To understand the prevalence, screening and management of TBI in pregnancy. Methods : A systematic review of 4 databases (Embase, Embase Classic, Medline, Cochrane Library) covering articles published from January 1st 2010 to April 30th 2018. Articles in English with relevant information on prevalence, screening strategies and treatment of TBI during pregnancy were eligible for inclusion. Results : Of 193 titles initially identified, 108 abstracts were eligible for review. Of these, 86 articles qualified for full text review and 22 were retained: 3 cohort studies, 2 case-control studies, and 17 cross-sectional studies. In the USA, the estimated prevalence of TBI ranged from 14 to 48% in women tested, and tuberculin skin test (TST) positivity was associated with ethnicity. The proportion of women who attended follow-up visits after positive tuberculin tests varied from 14 to 69%, while 5 to 42% of those who attended follow-up visits completed a minimum of 6 months of isoniazid treatment. One study raised the possibility of an association of pregnancy/post-partum state with INH hepatitis (risk ratio 2,5, 95% CI 0.8–8.2) and fatal hepatotoxicity (rate ratio 4.0, 95% CI 0.2–258). One study deemed INH safe during breastfeeding based on peak concentrations in plasma and breast milk after INH administration. Conclusion : Pregnancy is an opportunity to screen for TBI. Interferongamma release assays are likely comparable to tuberculin skin tests and may be used during pregnancy. Efforts should be made to improve adherence with follow-up and treatment post-partum. Further data are needed with respect to safety and feasibility of antepartum INH therapy, and with respect to alternative treatment regimens.
EFFECT OF ASIATIC MANGROVE (RHIZOPHORA MICRONATA) LEAVES EXTRACT AS ANALGESIC IN MALE ALBINO DDW MICE (MUS MUSCULUS L.) INDUCED BY 0,7% ACETIC ACID Nanuru, Erika Widianingsih; Dewi, Lestari; Wibowo, Prajogo
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 2 (2021): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i2.2313

Abstract

Background : Pain is an unpleasant emotional experience that illustrates ongoing tissue damage. Excessive use of non-steroidal anti-inflammatory drugs can cause peptic ulcer to gastric mucosal damage and perforation. Indonesia contains the largest area of mangrove forest in the world. There are 45 species of mangrove found and one of them is Asiatic Mangrove (Rhizophora mucronata). This type is easy to find and rich of alkaloids and flavonoids which can be used as analgesics. Method:  This study used post-test only control group design. The number of mice that used was 25 mice, divided into 5 groups. Which were given different therapies aquadest 10mL/KgBW, acetosal 150 mg/KgBW, extract of Rhizophora mucronata 250 mg/KgBW, 500 mg/KgBW, and 1000 mg/kg bw. The pain was induced by 0,7% glacial acetic acid at a dose of 10 mL/KgBW.  The writhes of the mice was being calculated with an interval of 10 minutes in 30 minutes. Result:  The results of the analysis showed the decrease in writhes of mice  in acetosal group dose 150 mg/kg bw, Rhizophora mucronata leaves extract dose 250 mg/kg bw, 500 mg/kg bw, and 1000 mg/kg bw. There was a significant difference in the results of the Mann-Whitney U test with p<0,05 in the aquadest group and the acetosal group with the Rhizophora mucronata leaves extract group dose 500 mg/kg bw, the difference between the acetosal group and the Rhizophora mucronata leaves extract group dose 250 mg/kg bw, and the difference between the Rhizophora mucronata leaves extract group dose 500 mg/kg bw and the Rhizophora mucronata leaves extract group dose 1000 mg/kg bw. Conclusion: Rhizophora mucronata leaves extract dose 500 mg/kg bw can provide analgesic effect and can reduce the writhing frequency in mice much better than acetosal group.

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