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Medica Hospitalia
ISSN : 23014369     EISSN : 26857898     DOI : https://doi.org/10.36408/mhjcm
Core Subject : Health,
Medica Hospitalia: Journal of Clinical Medicine adalah jurnal ilmiah yang diterbitkan RSUP Dr. Kariadi dan menerima artikel ilmiah dalam bahasa Indonesia dan bahasa Inggris yang diharapkan dapat menjadi media untuk menyampaikan temuan dan inovasi ilmiah dibidang kedokteran atau kesehatan kepada para praktisi dan akedemisi di bidang kesehatan dan kedokteran.
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Articles 584 Documents
Late Presentation of Arrhythmogenic Right Ventricular Cardiomyopathy : Role of Non Invasive Modalities for The Diagnosis Sungkar, Safir; Nugroho, Mochamad Arif
Medica Hospitalia : Journal of Clinical Medicine Vol. 6 No. 2 (2019): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (663.321 KB) | DOI: 10.36408/mhjcm.v6i2.394

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Background : Arrhythmogenic right ventricular cardiomyopathy(ARVC) is an inherited myocardial disease affecting predominantly young people and manifests as sustained ventricular tachycardia, sudden cardiac death (SCD) or heart failure. However, its first manifestation in older patients is infrequent. Diagnosis of ARVC remains a clinical challenge and need further investigation. Our case report investigated role of non invasive modalities for diagnosis of ARVC patient. Case Presentation : A 65 year old man was admitted to the hospital with symptoms of palpitationand near syncope. An Electrocardiogram (ECG) showed a sustained VT with LBBB morphology and inferior axis. The patient was cardioverted to sinus rhytm with a single 100J shock. Postcardioversion ECG showed an epsilon wave in right precordial leads. Echocardiography revealed extensive RV enlargement and reduce function. Our patient had three major (RV aneurysm, epsilon wave and T wave inversion) and one minor criteria (sustained LBBB type-VT with inferior axis)making the diagnosis of ARVC definite according to the revised Task Forced Criteria. Conclusion: ARVC may have a very late presentation and this diagnosis should be considered as a potential cause of sustained VT of RV origin among the elderly. ECG and echocardiography as non invasive modalities have an important role for the diagnosis of patients with suspected ARVC. Keywords :Arrhythmogenic right ventricular cardiomyopathy,ventricular tachycardia, sudden cardiac death, diagnosis.
Ketogenic Diet for Treatment 2-Year 9 Month Old Boy With Intractable Epilepsy Wijaya, I Made Ananta; Putranti, Alifiani Hikmah; Mexitalia, Maria
Medica Hospitalia : Journal of Clinical Medicine Vol. 6 No. 2 (2019): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (372.874 KB) | DOI: 10.36408/mhjcm.v6i2.395

Abstract

Background:The ketogenic diet (KD) is a high-fat, low-carbohydrate, and normal-protein diet that has been used for the treatment of medically refractory childhood epilepsy since the 1920s.The KD includes 80% fat, 15% protein, and 5% carbohydrate; the ratio of fat to carbohydrate plus protein ranges from 2:1 to 4:1.The purpose of the case report was to learn benefits and factors that influence the administration of the ketogenic diet in intractable epilepsy. Case:A 2-years 9 months old boy since 3 month of age the child begins seizure. Five month the child was diagnosed with epilepsy received one type of anti epileptic drug (AED). Seven months of age the child began control in outpatient clinic Neurology Department of Dr. Kariadi Hospital with a diagnosis of general epilepsy, were given 2 type of AEDs. Since10 month of age the child was given 3 type of AEDs. The child still often seizure, at 15 months was diagnosed intractable epilepsyand at 29monthof age, was programed to have long term EEG and KD during hospitalization. Conclusion:The administration of KD in 2-years9 months old boy with intractable epilepsyshowed benefits in reducing the frequency of seizures. Key word : Ketogenic Diet, Intractable Epilepsy, Child
Stent angioplasti pada anak hipertensi akibat stenosis arteri renalis di RSUP dr. Kariadi Muryawan, Muhammad Heru; Santoso, Antonius Gunawan; Mellyana, Omega
Medica Hospitalia : Journal of Clinical Medicine Vol. 6 No. 2 (2019): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.73 KB) | DOI: 10.36408/mhjcm.v6i2.396

Abstract

Background : Renal artery stenosis (RAS) causes 5-10% of all secondary hypertension (HT) in children. Percutaneous transluminal angioplasty (PTA) has proven beneficial for adult patients, but for a children there are varying result. This paper is to report the management of PTA in HT children due to RAS in Dr. Kariadi Hospital. Case report: Nine years 8 months boy with stage II HT since 4 years old, in a good nutritional status, complaints headaches, no family history of hypertension. Treatment with of nifedipine, captopril, valsartan and furosemide has not improved. Four months ago, the patient was treated by the Children's Nephrology and Radiology Division in Dr. Kariadi Hospital for 4 days. initial blood pressure 150/100 mmHg (stage II HT), normal eye examination, heart and kidney function, the angiographic results obtained severe right middle renal artery stenosis.teh stenosis reduced by PTA with dilated balloons up to 30%. One day after the procedure, blood pressure decreased to stage I HT, no complication involved, and the patient was discharged on day 4, with nifedipine, valsartan to control HT and aspilet as anti platelet aggregation. Evaluation 4 months after PTA obtained normal blood pressure. Discussion: HT renovascular children e.c. unilateral RAS performed by PTA has a good prognosis. Unilateral RASre-stenosis rates are less than 30%. Anti-hypertensive therapy is needed after ballooning or angioplasty stents. PTA in Dr. Kariadi Hospital can managed patient to make blood pressure normal. Conclusion: PTA management is an option in children with HT renovasculere.c SAR. Dr. Kariadi Hospital can be a referral to manage the case. Keywords: pediatric hypertension, RAS, PTA, Dr. Kariadi Hospital Latar belakang : Stenosis arteri renalis (SAR) menyebabkan 5-10% dari seluruh hipertensi (HT) sekunder pada anak. Percutaneous transluminal angioplasty (PTA) terbukti bermanfaat untuk pasien dewasa, namun pada anak hasilnya bervariasi. Tujuan makalah ini melaporkan tatalaksana PTA pada anak HT akibat SAR di RSUP dr Kariadi. Laporan kasus : Anak laki laki 9 tahun 8 bulan dengan HTderajatII sejak usia 4 tahun, status gizi baik, keluhan kadang-2 sakit kepala, tidak ada riwayat keluarga hipertensi. Pengobatan nifedipin, kaptopril, valsartan dan furosemid belum membaik. Empat bulan yang lalu pasien di rawat oleh Divisi Nefrologi Anak dan Radiologi di RSUP dr Kariadi selama 4 hari. Tekanan darah saat masuk 150/100 mmHg, pemeriksaan mata, fungsi ginjal dan jantung normal, Hasil angiografi didapatkan stenosis berat arteri renalis kanan pertengahan, dilanjutkan PTA dengan stent post dilatasi dengan balon, stenosis mejadi 30%. Satu hari paska tindakan, tekanan darah menurun menjadi HT derajat I, tidak ada kelainan dan dipulangkan pada hari ke 4, mendapat nifedipin, valsartan dan aspilet sebagai anti agregasi trombosit. Evaluasi 4 bulan paska PTA didapatkan tekanan darah normal. Pembahasan : HT renovaskuler anak e.c.SAR unilateral yang dilakukan PTA mempunyai prognosis baik. Angka re-stenosis SAR unilateral kurang dari 30%. Terapi anti-hipertensi diperlukan setelah pemasangan balon atau stent angioplasti. PTA di RSUP dr Kariadi berhasil membuat tekanan darah menjadi normal. Kesimpulan :Manajemen PTA merupakan pilihan pada anak dengan HT renovaskuler e.c SAR. RSUP dr Kariadi dapat menjadi rujukan dalam tatalaksana kasus tersebut. Kata kunci : hipertensi anak, SAR, PTA, RSUP dr Kariadi
Glycogen Rich Clear Cell Carcinoma Pada Payudara Finot, Finot; Puspasari, Dik; Amarwati, Siti
Medica Hospitalia : Journal of Clinical Medicine Vol. 6 No. 2 (2019): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (450.775 KB) | DOI: 10.36408/mhjcm.v6i2.397

Abstract

Background: Glycogen rich clear cell carcinoma is a rare neoplasm of the breast, with the incidence of 1.4-3% of all breast cancers. The tumour has distinct morphology, different from that of common breast cancers. Glycogen rich clear cell carcinomas are members of a heterogeneous group of neoplasms, including signet-ring, secretory and lipid-rich carcinomas of the breast. In general, clear cell breast carcinoma tends to follow an aggressive clinical course. Case report: To present a case of a 47 years old woman suffering from breast mass in the upper outer quadrant of her right breast. On macroscopic examination, the biopsy tumor sized 2x1.5x0.5 cm and solid with brown and white. Discussion: Microscopic examination showed breast tissue composed of tumor cells arranged in nets, trabeculae and singly dispersed. Tumor cells are moderately pleomorphic, have sharply defined border and polygonal contours. Cytoplasm is clear in more than 90% of cells and finely granular in few cells. Nuclei are hyperchromatic with clumped chromatin and prominent nucleoli. Occasional mitosis is also observed. Special stain (PAS Staining): Intracytoplasmic PAS positivity in tumor cells are variable. Immunohistochemistry ER (+) positive >20-50%, PR (+) positive <20%, HER2 (-) negative. The patient was diagnosed with glycogen rich clear cell carcinoma. Conclusion: Glycogen rich clear cell carcinoma of the breast is rare. Its clinical feature is rather aggressive and varies depending on special characteristics such as low grade. Keywords: Glycogen rich clear cell carcinoma, breast carcinoma, PAS staining Latar belakang: Glycogen rich clear cell carcinoma adalah kanker payudara yang jarang, dengan insidensi 1.4-3% dari semua kanker payudara. Tumor memiliki morfologi yang berbeda dari kanker payudara pada umunya. Glycogen rich clear cell carcinoma merupakan neoplasma heterogen yang termasuk karsinoma payudara signet-ring, sekretori dan kaya lipid. Secara umum, carcinoma ini cenderung mengikuti perjalanan klinis yang agresif. Tujuan: Laporan Kasus: Dilakukan pemeriksaan makroskopis jaringan tumor dari seorang perempuan berusia 47 tahun dengan massa payudara kanan di kuadran luar atas. Tumor biopsi berukuran 2x1.5x0.5 cm, komposisi padat, berwarna coklat dan putih. Dilakukan pemeriksaan histopatologi, imunohistokimia dan histokimia pewarnaan khusus PAS (Periodic Acid Schiff). Pembahasan: Pemeriksaan mikroskopis menunjukkan jaringan payudara dengan sel-sel tumor yang tersusun dalam jaring, trabekula dan tersebar tunggal. Sel-sel tumor cukup pleomorfik, hiperkromatik, kromatin kasar dan nucleoli prominent, mitosis dapat ditemukan, sitoplasma jernih lebih dari 90% sel dan granular halus dalam beberapa sel, memiliki garis batas dan beberapa bentuk poligon yang jelas. Hasil histokimia PAS (+) positif, Immunohistokimia ER (+) positif > 20-50% pada sel-sel tumor, PR (+) positif < 20%, HER2 (-) negatif. Dari hasil pemeriksaan tersebut, pasien didiagnosis Glycogen rich clear cell carcinoma. Kesimpulan: Glycogen rich clear cell carcinoma pada payudara adalah tumor yang jarang, perilaku klinisnya dilaporkan agak agresif sejauh ini, sangat bervariasi tergantung pada karakteristik khusus seperti tingkat rendah. Kata kunci: Glycogen rich clear cell carcinoma, karsinoma payudara, pewarnaan PAS.
HUBUNGAN LAMA WAKTU PASCA KEMORADIASI DENGAN DERAJAT DISFAGIA OROFARINGEAL PADA KARSINOMA NASOFARING Kusuma, Lirans Tia; Antono, Dwi; Muyassaroh, Muyassaroh
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 1 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.617 KB) | DOI: 10.36408/mhjcm.v8i1.400

Abstract

Abstract Background : Dysphagia can occur as a side effect in patients with nasopharyngeal carcinoma (NPC) receiving chemoradiation therapy. The reported incidence rate up to 83%. The degree of oropharyngeal dysphagia accosiated with the long time of post-chemoradiation in NPC is not yet clearly known. Objective : To analysis the degree of oropharyngeal dysphagia accosiated with the long time of post-chemoradiation in NPC. Method : Analysis observational research with cross sectional design. The subjects were patients with post-chemoradiation NPC at RSUP Dr. Kariadi Semarang who met the inclusion criteria. Determination of dysphagia status and degree of dysphagia by Gugging Swallowing Screen (GUSS). The complete details of the subjects were obtained from history and medical records. Chi-Squared is used for the statistical test. Outcome : Fifty five (100%) subjects had dysphagia, 48 (87.3%) subjects had mild degrees of dysphagia, no subjects with moderate degree of dysphagia were found, and 7 (12.7%) subjects had severe dysphagia. Long time of post-chemoradiation (p = 0.451), type of chemotherapy (p = 0.267), and therapeutic modality (p = 0.402) were not related to the degree of oropharyngeal dysphagia in NPC. Conclusion : The majority of subjects had mild degree dysphagia. Long time of post-chemoradiation, type of chemotherapy, and modality of therapy are not related to the degree of oropharyngeal dysphagia in NPC. Keywords: NPC, chemoradiation, degree of dysphagia, GUSS.
Pengaruh Pemberian Aromaterapi Lemon terhadap Skor Kecemasan Mahasiswi Fakultas Kedokteran Universitas Diponegoro Fitrikasari, Alifiati; Fajriyanti, Nur Isnaeni; Wardani, Natalia Dewi; Jusup, Innawati
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (252.522 KB) | DOI: 10.36408/mhjcm.v7i2.408

Abstract

Background: Based by Riskesdas in 2013, 6% of Indonesia’s population the age of 15 years old and more had emotional disorders which shown by symptoms of anxiety and depression. In university students, the study found that 25% of them had light anxiety, 60% had moderate anxiety, and 15% had severe anxiety. The mean of medical student who had anxiety symptoms around the world are 12-69%. Relaxation therapy able to decrease anxiety level, which by giving aromatherapy, it able to stimulates the brain to relax. Lemon is one of the aromatherapies that found effectively able to decrease anxiety symptoms by its refreshingly sharp smell and lifting the mood, which strengthening its user’s psyche. To measure the anxiety score, the author used the Zung Self-rating Anxiety Scale (ZSAS). The objective of this study aimed to investigate the effect of inhaling lemon aromatherapy on anxiety in female students of Medical Faculty of Diponegoro University Methods: This study used experimental pre and post-test without control design. Zung Self-rating Anxiety Scale was used to investigate the anxiety level of the samples. 32 persons volunteered as participants by 1 of them dropped out. The group inhaled lemon aromatherapy for 2 weeks. At the end of week 2, the participants’ anxiety was measured, and the results were statistically analysed. Saphiro-Wilk Test was used as the normality test while the results of the measured anxiety were tested by Wilcoxon Test. Results: There was a significant decreased anxiety score of the participants after inhaling lemon aromatherapy for two weeks. Based by pre and post-test result, the mean of anxiety score decreased from 37.32 to 31.84 (p=0.000). Conclusions: Lemon aromatherapy essential oil is able to significantly decrease the anxiety score of female students of Faculty of Medicine Diponegoro University. Keywords: Lemon aromatherapy, anxiety, medical student
Penentuan Jenis Kelamin berdasarkan Sidik Hypothenar Widya Iswara, Raja Al Fath; Rohmah, Intarniati Nur; Santosa, Santosa; Relawati, Ratna
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (273.755 KB) | DOI: 10.36408/mhjcm.v7i1.419

Abstract

Background : Hypothenar regio in palmar is an area that is often contact with surfaces while doing the activity which can establish print or pattern of protruding line (ridge) that can be used in identification process. One of the important identification to sex determination. The aims of this study is to sex determination based on hypothenar print. Methods : The study was a cross sectional study. Subjects were 300 students underwent clinical clerkship in Forensic and Medicolegal Dr. Kariadi Semarang hospital during October-December 2017, age 21-26 years, male (n = 150) and female (n = 150). Hypothenar print measured by calculating the average number of ridge hypothenar palm on the side of the top, middle and bottom in each area measuring 5 mm x 5 mm. A Mann-Whitney test was performed to analyze the the difference between left and right hypothenar ridge. Spearman correlation test was conducted to measure the association of hypothenar prints and sex. Results : In male, the average number of hypothenar ridge on the right palm was 10 (7-12)/25 mm2, while the left palm 10 (7-13)/25 mm2. In female, the average number of hypothenar ridge on the right palm was 12 (8-16)/25 mm2, while the left hand was 12 (8-16)/25 mm2. The was a significant difference between the right hand hypothenar ridge (p = 0.008) and the left hand hypothenar ridge (p = 0.017) between male and female. There was a significant correlation between hypothenar prints and sex (p = 0.000). Conclusion : Hypothenar prints can be use in sex determiation where female have more hypothenar ridge count and density than male.
Hubungan Pengetahuan dan Persepsi Ibu dengan Pemanfaatan Layanan Provider Initiated HIV Testing Counselling di Maluku Nababan, Sudarwati; Papilaya, Maritjie Fransina; Udji Sofro, Muchlis Achsan
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.976 KB) | DOI: 10.36408/mhjcm.v7i1.420

Abstract

Latar belakang : Maluku Tenggara berada pada peringkat ke-2 tertinggi kasus HIV/AIDS dari 11 kabupaten di Maluku. Ibu rumah tangga di Wilayah Kerja Puskesmas Kolser rentan tertular HIV dari suaminya. Rumah tangga daerah ini 40% tidak tinggal bersama karena suami bekerja tidak menetap, selain itu di daerah ini juga terdapat lokalisasi. Ibu hamil yang memanfaatkan layanan Provider Initiated HIV Testing Counselling tahun 2017 sebanyak 76% dari 321 kunjungan, data ini menunjukkan Puskesmas Kolser belum mencapai target Maluku Tenggara terkait program yakni 89%. Tujuan : Mengetahui faktor yang mempengaruhi pemanfaatan layanan PITC oleh ibu hamil di Wilayah Kerja Puskesmas Kolser. Metode : Penelitian ini menggunakan metode observasional analitik pendekatan cross-sectional. Subjek 155 ibu hamil di Wilayah Kerja Puskesmas Kolser yang diperoleh dengan tehnik total sampling. Instrumen penelitian kuesioner, data dikumpulkan dengan metode face to face dan dianalisis menggunakan uji chi square dan regresi ogistik ganda metode backward Hasil : Terdapat hubungan pengetahuan (p=0,000), persepsi manfaat pemeriksaan HIV (p=0,007), dan persepsi kerentanan (p=0,040) dengan pemanfaatan layanan PITC. Ibu hamil yang mempunyai pengetahuan rendah beresiko 3,825 kali lebih besar untuk tidak memanfaatkan layanan PITC dibandingkan ibu hamil dengan pengetahuan yang tinggi. Simpulan : Pengetahuan ibu hamil merupakan faktor yang paling signifikan terkait pemanfaatan layanan PITC di Wilayah Kerja Puskesmas Kolser Maluku. Kata kunci : Ibu hamil, PITC, pengetahuan, HIV/AIDS Relationship Between Mother’s Knowledge and Perception with the Use of Provider Initiated HIV Testing Counselling in Maluku Background : Southeast Maluku district is ranked the 2th highest number of HIV/AIDS cases from 11 district in Maluku. Housewives in Kolser health center are at risk of contracting HIV from their husbands. Families in this area 40% do not live together, because the husband works non permanently. Another reasons is that in this area there are prostitute houses. Kolser health center is one of the Puskesmas that serves HIV testing in Southeast Maluku. Pregnant women who come to visit PITC in 2017 were 247 mothers out of 321 visits. Purpose : This study aims to explore the behavioural factors that influence pregnant women’s to PICT at the Kolser health center. Methods : This study employed a cross-sectional design. The sample of this study consists of 155 pregnant mothers in Puskesmas Kolser, selected by using total sampling. Data was collected using face to face interview by trained enumerators. Data were then analysed with chi-square test and logistic regression backward method. Results : The finding of this study is that there is a relationship between knowledge (p=0,000), perceived benefit (p=0,007), perceived susceptibility (p=0,040) with the visit of pregnant women to PITC. Compared to pregnant women who do not have sufficient on HIV/AIDS, those who have sufficient knowledge on HIV/AIDS was 3.825 times more likely to come visit PITC Conclusion : sufficient knowledge of pregnant women is the most significant factor related to the utilization of PITC in Kolser health center. Keywords : pregnant women, PITC, knowledge, HIV/AIDS
Perbedaan Jumlah Trombosit, Leukosit Dan Eritrosit Dengan Kecepatan Sentrifugasi Yang Berbeda Pada Pembuatan Platelet Rich Plasma Fajaryani, Dwi; Rahayu, Muji; Limijadi, Edward Kurnia Setiawan
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.957 KB) | DOI: 10.36408/mhjcm.v7i1.421

Abstract

Latar belakang : Platelet Rich Plasma (PRP) adalah plasma dalam jumlah sedikit dengan jumlah trombosit banyak, didapatkan melalui sentrifugasi. Trombosit dalam PRP penting untuk penyembuhan luka dan memperbaiki jaringan rusak. Kecepatan sentrifugasi berperan penting dalam memisahkan sel darah merah dengan plasma dan menghasilkan platelet konsentrat. Penelitian ini bertujuan untuk mengetahui perbedaan jumlah trombosit, leukosit dan eritrosit dengan kecepatan sentrifugasi yang berbeda pada pembuatan platelet rich plasma. Metode: Penelitian belah lintang pada orang sehat di laboratorium RSUP Dr. Kariadi Semarang bulan Juli 2018. Darah vena ditampung dalam tabung sitras dan Ethylenediaminetetraacetic acid (EDTA). Darah EDTA untuk pemeriksaan hematologi rutin dengan hematology analyzer, hasil normal dilanjutkan pembuatan PRP dari darah sitras 3,2 % dengan dua metode sentrifugasi, dengan kecepatan 100xg-400x selama 10 menit (metode PRP1) dan kecepatan 540xg-2270xg selama 10 menit (metode PRP2). Kedua produk PRP dilakukan pemeriksaan jumlah trombosit, leukosit dan eritrosit. Data dianalisis dengan uji Kruskall Wallis dan Mann Whitney, signifikan bila p< 0.05. Hasil : Sampel terdiri dari 35 orang responden. Terdapat perbedaan bermakna jumlah trombosit, leukosit dan eritrosit pada pembuatan PRP-1 dan PRP-2 (p<0.001) Simpulan : Terdapat perbedaan jumlah trombosit, leukosit dan eritrosit pada kecepatan sentrifugasi yang berbeda. Kecepatan sentrifugasi pada metode pembuatan PRP disarankan dalam pembuatan PRP. Kata kunci : PRP, trombosit, leukosit, eritrosit Background : Platelet Rich Plasma (PRP) consisting of small amounts plasma with many platelet, which was obtained by centrifugation process. The platelet in PRP are essential for wound healing and repair of damaged tissue. The centrifugation velocity plays an important role in separating red blood cells by plasma and producing concentrated-platelets. This study aims to determine differences the number of platelets, leukocytes and erythrocytes with different centrifugation rates on platelet rich plasma production. Methods: This cross sectional study was conducted on 35 healthy people in the laboratory of Kariadi Hospital Semarang in July 2018. The blood vein were collected in Citrate 3.2 % and Ethylenediaminetetraacetic acid (EDTA) tubes. Sample EDTA for complete blood counts, if the results were normal then continued with PRP preparation in 2 different methods centrifugation (PRP 1 at 100xg-400xg for 10 minutes and PRP 2 at 540xg-2270 xg for 10 minutes). Both of the PRP products were calculated the amounts of platelet, leukocytes, and erythrocytes. The data were analyzed by Kruskall Wallis and Mann Whitney, p < 0.05 was considered as significant. Results : There was a significant difference between PRP-1 and PRP-2 method in platelet counts, leukocytes count and erythrocytes count (p<0.001). Conclusion : There was differences in platelet count, leukocytes count and erythrocytes count with different centrifugation rate. Centrigugation rate on PRP-1 method is recommended in the production of PRP. Keyword PRP, platelets, leukocytes, erythrocytes
Faktor Risiko Air Bone Gap Pada Otitis Media Supuratif Kronik Inardi, Yoke Kurniawan; Widodo, Pujo; Naftali, Zulfikar; Yusmawan, Willy
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.224 KB) | DOI: 10.36408/mhjcm.v7i1.422

Abstract

Latar belakang : Kehilangan pendengaran merupakan komplikasi otitis media kronik (OMSK) yang paling sering, jenis kehilangan pendengaran yang tersering adalah tuli konduktif, yang disebabkan oleh adanya air bone gap (ABG), ABG pada pasien OMSK mempunyai variasi yang berbeda-beda dan karakter yang khas berdasarkan faktor risiko. Tujuan : Menganalisis hubungan faktor risiko dengan ABG pada penderita OMSK. Metode : Penelitian desain observational analitik retrospektif di RSUP Dr Kariadi Semarang pada bulan September 2018 - Januari 2019. Data diambil dari rekam medis. jumlah sampel ditentukan sebanyak 100. Analisis data dengan uji chi-square. Hasil : Jenis kelamin laki-laki 46 orang, wanita 54 orang, rerata usia 32 tahun. Status osikula, lama sakit, kolesteatom, luas perforasi membran telinga berhubungan terhadap ABG (p <0,05). Kesimpulan : Faktor risiko (status osikula, lama sakit, kolesteatom, perforasi membran timpani) berhubungan dengan air bone gap pada penderita OMSK. Kata kunci : Air bone gap, faktor risiko, otitis media supuratif kronik. Background: Hearing loss is the most frequent complication of chronic otitis media (CSOM), hearing loss is usually caused by conductive deafness caused by the presence of an air bone gap (ABG). ABG in CSOM patients has different variations and distinctive characters based on the factors. Objective: To analyze the relationship of risk factors ABG in CSOM patients. Methods: Observational analytic study with a retrospective observational analytic design at Dr. Kariadi Hospital Semarang in September 2018 - January 2019. Subjects were 100 patients. Data retrieval is done based on medical records about history taking, physical examination and investigation. Data were analyzed by Chi-square test. Results: A total male 46 and female. Avarage age 32 years. Oscular status, duration of illness, cholesteatom, area of ??ear membrane perforation associated with ABG (p <0.05). Conclusion: Risk factors (osicular status, duration of illness, cholesteatom, tympanic membrane perforation) associated with air bone gap in CSOM patients. Keywords: Chronic supurative otitis media, air bone gap, risk factors