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Budi Santoso
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juxta@journal.unair.ac.id
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INDONESIA
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Published by Universitas Airlangga
ISSN : 19073623     EISSN : 26849453     DOI : -
Core Subject : Health, Science,
Juxta (Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga) is a scientific peer-reviewed medical doctor which relevant to a medical doctor and other health-related professions by the Faculty of Medicine Universitas Airlangga, Indonesia. Juxta provides a forum for original article to the editor and it will be published Two-times a year. Studies that focus on evaluating and understanding the complex medical importance are welcomed in Juxta.
Arjuna Subject : -
Articles 191 Documents
Effects of Javanese Ginseng Root Extracts (Talinum triangulare W.) on Thickness of Seminiferous Tubules of Male Rats (Rattus norvegicus) Exposed by Cigarette Smoke Rifqi Misbahuddin Nur; Anung Putri Ilahika; Desy Andari
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.6-11

Abstract

Highlights:1. Infertility in men can be caused by smoking, the content of free radicals in cigarettes can affect male reproductive organs.2. Javanese ginseng root (Talinum triangulare w.) extract contains ginsenoside which is a natural antioxidant to reduce free radical levels inside the body.3. Javanese ginseng root (Talinum triangulare w.) extract was able to reduce free radical levels as seen from the appearance of the seminiferous tubules of male white rats exposed to cigarette smoke. AbstractIntroduction: Cigarette smoke contains various radical chemical compounds that can increase oxidative stress, which may cause lipid peroxidation in the body and affect various different organs. This study aimed to examine the effects of Javanese ginseng root extracts (Talinum triangulare W.) on the thickness of seminiferous tubules of white male rats (Rattus norvegicus) exposed to cigarette smoke.Methods: This was an experimental study with a randomized controlled method and a post-test control group design. Post-test control group design with 15 white male rats was divided into five groups: a normal group, a control group (exposed to cigarette smoke), and three treatment groups (exposed to cigarette smoke and Javanese ginseng root extract with doses of 12.5mg, 25mg, and 50mg/200grBW, respectively) for 30 days. The seminiferous tubule thickness was observed using H&E staining under a light microscope with 200x magnification in five fields view.Results: One-way ANOVA showed that Javanese ginseng root extracts significantly affected seminiferous tubule thickness (p = 0.000). With a dose of 12.5mg/200mgBW, Javanese ginseng root extract started to show a significant effect (p = 0.000) on the thickness of the epithelium of the seminiferous tubules. The group exposed to cigarette smoke had an average thickness of seminiferous tubules of 7.92 mm, the normal group had an average thickness of 9.13 mm, and treatment groups with doses 12.5mg, 25mg, and 50mg/200gBW had an average thickness of 11.85 mm, 12.7mm, and 14.69 mm, respectively.Conclusion: Javanese ginseng root extract increased seminiferous tubule thickness in white male rats exposed to cigarette smoke.
Risk Factors of Chronic Kidney Disease (CKD) in Type 2 Diabetes Mellitus (DM) Patients at Dr. Soetomo General Academic Hospital, Surabaya Joshua Teofilus Sutadji; Agung Pranoto; Risky Vitria Prasetyo
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.12-16

Abstract

Highlights:1. The highest risk was a history of hypertension, followed by a history of low HDL levels.2. Patients with type 2 DM at Dr. Soetomo General Academic Hospital, Surabaya, had a greater risk of developing CKD for patients with a history of hypertension (3.801 times higher) and patients with a history of low HDL (3.356 times higher). AbstractIntroduction: Type 2 diabetes mellitus (DM), categorized as a non-communicable disease, has become a global health concern. This study aimed to identify the risk factors for chronic kidney disease (CKD) in type 2 DM patients at Dr. Soetomo General Academic Hospital, Surabaya.Methods: This was a case-control study. The samples were collected using consecutive sampling methods from the medical records Dr. Soetomo General Academic Hospital, Surabaya. The total samples were 158 patients consisting of 79 cases and 79 controls. Independent variables were a history of uncontrolled HbA1c levels; hypertension; high triglyceride (TG) levels; low high-density lipoprotein (HDL) levels, high low-density lipoprotein (LDL) levels, and being overweight. The dependent variable was CKD. Samples were analyzed using the Chi-Square test and logistic regression.Results: From six independent variables that were analyzed, two variables had significant results based on the Chi-Square test. Logistic regression was performed and showed the significant results between risk factors of CKD and type 2 DM patients at Dr. Soetomo General Academic Hospital, Surabaya, were a history of hypertension (OR = 3.801, 95% CI = 1.875-7.706) and a history of low HDL levels (OR = 3.356, 95% CI = 1.650-6.827). The highest risks were a history of hypertension followed by a history of low HDL levels.Conclusion: Type 2 DM patients at Dr. Soetomo General Academic Hospital, Surabaya, with a history of hypertension and a history of low HDL had a greater risk of developing CKD.
Clinical Profile of Children with Pyelonephritis and Cystitis in Dr. Soetomo General Academic Hospital, Surabaya Lutifta Hilwana; Ninik Asmaningsih Soemyarso; Atika Atika
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.1-5

Abstract

Highlights:1. In patients younger than one year old, cystitis was more frequent in boys. Meanwhile, in patients aged 1-5, girls were more frequent in pyelonephritis and cystitis.2. In pyelonephritis, all patients had fever, followed by diarrhea and lethargy.3. Urinary symptoms, such as dysuria and hematuria, were more frequent in cystitis than in pyelonephritis. AbstractIntroduction: Urinary tract infection (UTI) is a common infection in children. Prompt diagnosis and treatment of this infection are important to prevent further damage to the kidney. This study aimed to examine the clinical profile of children with pyelonephritis and cystitis in Dr. Soetomo General Academic Hospital, Surabaya.Methods: This was a descriptive study conducted in Dr. Soetomo General Academic Hospital, Surabaya, from June 2013 until December 2015, using secondary data and presented by percentage. Samples included in this study were children aged two months to five years old with UTI as a primary or secondary diagnosis of diarrhea and had urine culture results ≥ 105 CFU/ml.Results: There were 30 patients with pyelonephritis and 27 patients with cystitis. The prevalence of pyelonephritis was 0.285% and of cystitis was 0.247%. In pyelonephritis patients younger than one-year-old, boys and girls were equal. However, boys (60%) were more frequent in cystitis patients. In both pyelonephritis and cystitis patients aged 1-5, girls were more frequent (56.3%; 64.7%).  In pyelonephritis patients, all patients were found with fever, followed by diarrhea (60%) and lethargy (56.7%) as the two most common symptoms. The two most common symptoms in cystitis patients were lethargy (44.4%) and irritability (33.3%). Urinary symptoms, such as dysuria and hematuria, were more frequent in cystitis (11.1%; 7.4%) patients than in pyelonephritis patients.Conclusion: Boys were more frequent to suffer urinary tract infections. Systemic symptoms were frequently found in pyelonephritis patients, while urinary symptoms were more frequent in cystitis patients.
Conjunctivitis Patients in the Ophthalmology Outpatient Clinic Dr. Soetomo General Academic Hospital, Surabaya, in 2017 Angeline Hartadhi; Ismi Zuhria; Bambang Hermanto
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.17-20

Abstract

Highlights:1. Ginger (Zingiber officinale) has antimicrobial activity against UPEC which commonly causes UTI in women.2. The MIC and MBC of ginger against UPEC in this study was 1000 mg/ml. AbstractIntroduction: Conjunctivitis is a self-limiting disease. It can be diagnosed through clinical signs found in the eye examination. The purpose of this study was to define the characteristics of conjunctivitis patients in the ophthalmology outpatient clinic Dr. Soetomo General Academic Hospital, Surabaya, in 2017.Methods: This was a retrospective descriptive observational study of all conjunctivitis patients from the medical history in the ophthalmology outpatient clinic Dr. Soetomo General Academic Hospital, Surabaya, in 2017.Results: There were 497 patients included in this study. Most patients with conjunctivitis were 0-9 years old (19.32%). The most common sign of conjunctivitis was conjunctival hyperemia (80.89%), followed by eye discharge (24.14%), eyelid edema (8.05%), blepharospasm (5.63%), and papillary hypertrophy (5.03%). Most cases of conjunctivitis were bilateral (58.75%). Conclusion: The majority of conjunctivitis was bilateral conjunctivitis. It commonly affects children under ten years old. The most typical finding was conjunctival hyperemia.
Diagnostic Accuracy of Clinical Features, Laboratory Features, and Ultrasound Imaging Compared to Intraoperative Findings in Patients with Obstructive Jaundice Yudith Meityana Hernandita; Tomy Lesmana; Alphania Rahniayu
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.21-25

Abstract

Highlights:1. Patients with obstructive jaundice have either benign or malignant underlying etiologies.2. Ultrasound imaging had the highest accuracy in diagnosing the etiology of obstructive jaundice among other examinations, such as clinical signs and laboratory tests. AbstractIntroduction: Jaundice due to biliary obstruction can be caused by a diverse group of diseases, including both benign and malignant etiologies. This study aimed to evaluate the accuracy of clinical features, laboratory features, and ultrasound imaging in diagnosing the etiology of obstructive jaundice with intraoperative findings as the gold standard.Methods: This was an observational cross-sectional analytic study conducted on 49 subjects by obtaining patients’ data from medical records in the Medical Record Center Dr. Soetomo General Academic Hospital, Surabaya. Collected data were statistically analyzed using a diagnostic test.Results: In this study, sensitivity (Sn), specificity (Sp), and accuracy of each feature in differentiating masses and stones as the etiology of obstructive jaundice were obtained. Progressive jaundice had Sn 88.2%, Sp 37%, and accuracy 56.8%. Complaints of fever had Sn 73.9%, Sp 90.9%, and accuracy 79.4%. Courvoisier’s law had Sn 61.5%, Sp 61.5%, and accuracy 61.5%. Serum CA 19-9 had Sn 75%, Sp 58.3%, and accuracy 67.9%. Ultrasound imaging had Sn 81.8%, Sp 100%, and accuracy 93.3%.Conclusion: Ultrasound imaging had the highest accuracy in diagnosing the etiology of obstructive jaundice, followed by complaints of fever, serum CA 19-9, Courvoisier’s law, and progressive jaundice, respectively.
The Incidence Pattern of Electrical Burns at the Department of Plastic Surgery Dr. Soetomo General Academic Hospital, Surabaya, from January 2014 to December 2017 Merilyne Merilyne; David Sontani Perdanakusuma; Linda Astari
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.26-29

Abstract

Highlights:1. Electrical burns may progress even when the source has been removed.2. The most common age group to suffer from electrical burns was the 26–35 years old group.3. There was a significant association between electrical burns and the productive age of male employees who work in the private sector. AbstractIntroduction: Burns are direct or indirect damage to the skin tissue and can reach internal organs. This study aimed to investigate the incidence pattern of electrical burn patients at the Department of Plastic Surgery Dr. Soetomo General Academic Hospital, Surabaya, from 1 January 2014 to 31 December 2017, focusing on the age, gender, and occupation aspect of the patients.Methods: This was a descriptive retrospective study evaluating 50 patients treated for electrical burns from 1 January 2014 to 31 December 2017 using the patients’ medical records. The parameters assessed were age, gender, occupation, cause of injury, and annual incident. The data was collected from the medical records Dr. Soetomo General Academic Hospital, Surabaya.Results: Most electrical injuries occurred in May, as many as 12 (24%) patients. There were 49 (98%) male and 1 (2%) female patients. The patients ranged from 8–60 years old, with 17 (34%) patients in the 26-35 age group. 76% of patients were private employees. Work accidents caused approximately 82% of electrical injuries.Conclusion: There was a significant association between electric burns with males at productive age and working as private employees. Many electric accidents occurred while working, especially in May.
Profiles of Clinical and Liver Function Test of Hepatitis B and C Patients with Liver Cirrhosis Andreas Novaldi Watang; Aryati Aryati; Ulfa Kholili
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.30-35

Abstract

Highlights:1. Liver cirrhosis due to viral hepatitis is still a big problem in developing countries.2. There were no significant differences in clinical and laboratory profile results between patients with liver cirrhosis caused by hepatitis B and C. AbstractIntroduction: Liver cirrhosis is a degenerative liver disease that ranks 14th as a global problem and has a high prevalence rate. This study aimed to determine the clinical and laboratory profile of inpatients with liver cirrhosis.Methods: Medical record data of liver cirrhosis patients at Dr. Soetomo General Academic Hospital, Surabaya, in 2018-2019, were used in this cross-sectional descriptive observational study. The results were analyzed statistically to determine the different profiles between patients with liver cirrhosis caused by hepatitis B and C.Results: 112 subjects in this study had liver cirrhosis caused by hepatitis B or C. The majority of cirrhotic patients were males over 40 years old. Melena was the most frequent complaint, and abdominal enlargement and hepatitis B virus (HBV) infection were the most common causes. Liver function tests in hepatitis B and C patients respectively showed albumin results of 2.73 g/dL (± 0.54); 2.75 g/dL (± 0.61), prothrombin time was 14.75 seconds (10.80-49.40); 14.9 seconds (11.1-19.1), direct bilirubin 1.17 mg/dL (0.9-17.05); 0.82 mg/dL (0.12-8.43), total bilirubin 2.18 mg/dL (0.28-24.9); 1.58 mg/dL (0.38-9.7), AST 50.5 U/L (16-826); 48.5 U/L (31-545), ALT 51.5 U/L (8-869); 38.5 (12-127). Subjects with hepatitis B and C had a median length of stay of 7.00 days, with an overall mean of 7.16 days. There was no significant difference in the results between patients with liver cirrhosis due to hepatitis B and C.Conclusion: There was no significant difference between patients with liver cirrhosis caused by hepatitis B and C.
In Vitro Antibacterial Activity of Averrhoa bilimbi Leaves Ethanol Extract Against Salmonella typhi Margaretha Nathania; Eddy Bagus Wasito; Nurina Hasanatuludhhiyah
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.43-47

Abstract

Highlights:1. Typhoid fever, a major health problem for developing countries, requires alternative therapy to reduce drug resistance.2. A. bilimbi, a native plant of Indonesia, has antibacterial potential, which is effective against S. typhi in vitro. AbstractIntroduction: Some native plants in Indonesia have potential effects on health and medication. This study aimed to determine the potential antibacterial effect of Averrhoa bilimbi (A. bilimbi) leaves ethanol extract against Salmonella typhi (S. typhi) bacteria. Methods: This was an experimental study. The antibacterial potency of A. bilimbi leaves was measured against S. typhi in vitro. Different concentrations of the leaves’ ethanol extract were prepared. The minimum inhibitory concentration (MIC) was evaluated by a macro-dilution method using Mueller Hinton broth. The minimum bactericidal concentration (MBC) value was observed by subculturing the specimen from the previous dilution tube to the nutrient agar.Results: The MIC of A. bilimbi leaves ethanol extract against S. typhi bacteria could not be determined because all the treatment tubes’ colors were dark and turbid. Meanwhile, the MBC value was at 500 mg/ml.Conclusion: A. bilimbi leaves extract had potential bactericidal effects against S. typhi with a MIC value that could not be determined.
Prevalence of Spontaneous Delivery and Cesarean Section in Pregnant Patients with Myopia at Pregnancy Clinic Dr. Soetomo General Academic Hospital, Surabaya Rosalia Adriani Malika; Ernawati Ernawati; Prillia Tri Suryani
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.48-51

Abstract

Highlights:1. The selection of delivery methods in pregnant patients with myopia is needed to prevent blindness.2. Although there was no report of retinal detachment either in spontaneous delivery or in cesarean section in this study, all pregnant patients with pathologic myopia or peripheral retinal degeneration should be consulted by Ophthalmologist. AbstractIntroduction: The selection of delivery methods in pregnant patients with myopia is needed to prevent blindness. This study aimed to calculate spontaneous delivery and cesarean section prevalence in pregnant patients with myopia.Methods: This was a descriptive epidemiology study using medical records of Maternity Outpatients Dr. Soetomo General Academic Hospital, Surabaya, from September 2012 to September 2014. Age, stage of myopia, and delivery method data were taken. The sample in this study was all pregnant patients with myopia, as many as 30 patients.Results: Forty percent of pregnant patients with myopia were in the 21-25 age group. There were three patients with low myopia (10%), seven patients with moderate myopia (23.33%), and 20 patients with high myopia (66.66%). More than half of the pregnant patients with myopia had a cesarean section (66.66%), and ten had a vaginal delivery (33.33%). The most indications of cesarean sections were non-myopia in 14 patients (70%), and only six indicated myopia (30%). Myopia was not a primary indication for cesarean sections in Maternity Outpatients Dr. Soetomo General Academic Hospital, Surabaya.Conclusion: Although there was no report of retinal detachment either in spontaneous delivery or in cesarean section in this study, all pregnant patients with pathologic myopia or peripheral retinal degeneration should be consulted by an Ophthalmologist.
Energy Adequacy, Body Composition, and Menstrual Cycle Disorder: A Correlation Study on Medical and Midwifery Students Siti Aria Rahmani Novianto; Bambang Purwanto; Budi Prasetyo
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 1 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I12023.36-42

Abstract

Highlights:1. Menstrual cycle disturbance is related to organic and non-organic factors.2. BMI, waist circumference, and energy adequacy did not have a significant correlation with menstrual cycle frequencies among medical students. AbstractIntroduction: Menstrual cycle disturbance is related to irregular reproductive hormones, which are influenced by organic and non-organic factors. This study aimed to determine the correlation between energy adequacy, body composition, and menstrual cycle disorder. Methods: This was an observational analytic study with a case-control design. The population of this study was medical and midwifery students in the Faculty of Medicine, Universitas Airlangga, Surabaya. 72 subjects consisted of 36 women with a normal menstrual cycle between 24–38 days and 36 women with a menstrual cycle length of <24 days or >38 days. Data about body composition, energy adequacy, and menstrual cycle were all collected by questionnaire. Data were analyzed by Spearman and Continency Coefficient correlation.Results: Most participants (66.7%) had normal body mass index (BMI), while 19.4% were overweight. Meanwhile, waist circumference in 63.9% of subjects was categorized as not obese. The participants' physical activities ranged from sedentary to vigorous (0 to 7386 MET-minutes/week). Less than one-third of the participants (27.8%) had an energy balance, while in most subjects (56.9%), energy adequacy was classified as deficit or negative energy balance. The statistics showed a p-value >0.05 in BMI (p = 0.231), waist circumference (p = 0.141), and energy adequacy (p = 0.389) with the menstrual cycle, indicating no correlation between BMI, energy adequacy, and waist circumference with menstrual cycle frequencies.Conclusion: Statistical analysis showed no correlation between energy adequacy, BMI, and waist circumference with menstrual cycle frequency disorder in students in the Faculty of Medicine, Universitas Airlangga, Surabaya.

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