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Eri Hendra Jubhari
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INDONESIA
MDJ (Makassar Dental Journal)
Published by Persatuan Dokter Gigi Indonesia Cabang Makassar
ISSN : 20898134     EISSN : 25485830     DOI : 10.35856/mdj
Core Subject : Health,
Dentistry
The journal receives a manuscript from the following area below Dentistry science and development with interdisciplinary and multidisciplinary approach: Dental Public Health and Epidemiology Oral and Maxillofacial Surgery Dental Conservation and Endodontics Preventive Dentistry Biomedical Dentistry Dental Radiology Pediatric Dentistry Oral Pathology Prosthodontics Traumatology Oral Biology Biomaterials Orthodontics Periodontics
Arjuna Subject : Kedokteran Gigi - Kedokteran Gigi (Lain-Lain)
Articles 931 Documents
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The use of fig latex as a dentine deproteinisation agent prior to adhesive restoration procedures: Pemanfaatan getah buah ara sebagai agen deproteinisasi dentin sebelum prosedur restorasi adesif A. Abdillah; Aliyah Rajab; Agrista Aulia Amrin; Christine Anastasia Rovani
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1057

Abstract

The success of adhesive restorations is greatly influenced by the quality of the bond between the restorative material and the dentine. A deproteinising agent is required to remove denatured collagen without damaging the dentine structure. Fig latex (Ficus carica), which contains the proteolytic enzyme ficin, is be-ing developed as a natural alternative material due to its ability to degrade proteins, its biocompatibility, and its antibacterial and anti-inflammatory proper-ties. This article evaluates the potential of ficin as a dentine deproteinisation agent prior to adhesive restoration procedures by analysing its effect on adhesive bond strength, hybrid layer quality, and the effectiveness of dentine deproteinisation. A search for scientific articles was conducted in the Google Scholar, Web of Science, and PubMed databases using keywords related to ficin, proteolytic enzymes, and dentine deproteinisation. Articles meeting the inclusion cri-teria were then systematically analysed in accordance with the PRISMA guidelines. Based on research and clinical reports, it appears that ficin, as a proteo-teolytic enzyme, is effective when used as a deproteinisation agent on enamel and dentine surfaces prior to adhesive procedures; it is capable of improving bond quality, optimising hybrid layer formation, and serving as a safe and efficient alternative in restorative dental procedures.
Potential utilization of marine-based natural biomaterials: Potensi pemanfaatan marine biomaterials dari bahan alam berbasis laut Ainun Rezky Ramadhani; Jessica Adam Panggalo; Fadillah Ilmi; Acing Habibie Mude
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1065

Abstract

Biomaterials are natural or synthetic materials used to repair, replace, support, or restore tissue function in the human body. Marine-derived biomaterials, such as collagen, alginate, and chitosan, possess biocompatible, bioactive, and biodegradable properties, making them widely used in dentistry, particularly in rege-nerative therapies. This literature review evaluates the potential utilization of marine-based biomaterials as natural agents in the development of regenera-tive dentistry therapies and their clinical applications. It is concluded that marine-based biomaterials such as collagen, alginate, chitosan, coral, and carragee-nan show promising potential in regenerative dentistry and may be applied in various clinical settings. However, further studies and clinical trials are required to confirm their effectiveness, safety, and standardization for clinical application.
Early two-stage implant placement in region 46: Pemasangan implan gigi dengan teknik delayed two-stage pada regio 46 Aditya Priagung Prakosa; Elfina Sara Raharjo; Rizki Bagus Priharnanto
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1069

Abstract

The presence of infection at the extraction site can affect the timing of implant placement and the success of treatment. This case report describes the ma-nagement of the loss of the right lower first molar using the early two-stage implant placement technique following a change in the treatment plan. A 25-year-old man presented with a residual root of tooth 46 and wished to undergo rehabilitation using implants. Clinical examinations and CBCT scans were performed for treatment planning. Immediate implant placement was initially planned; however, an abscess was discovered during extraction, leading to a change in the plan to early implant placement. Following an eight-week healing period, the implant was placed using a two-stage surgical technique, followed by the place-ment of a healing abutment and a final restoration in the form of a screw-retained crown. Clinical and radiographic evaluation demonstrated good healing and implant stability. It was concluded that the early two-stage implant placement technique yields good clinical results in areas with a history of local infection when supported by an appropriate treatment plan and an adequate healing period.
A comparison of the effectiveness of 17% EDTA and 6.25% pineapple peel extract in removing the smear layer in the apical third of the root canal: Perbandingan efektivitas EDTA 17% dan ekstrak kulit nanas 6,25% untuk menghilangkan lapisan smear pada sepertiga apikal saluran akar Noor Hikmah; Rianti; Nurhayaty Natsir; Juni Jekti Nugroho
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1072

Abstract

The smear layer is a thin layer consisting of organic and inorganic substances that can potentially cause microleakage. Therefore, the removal of the smear layer is crucial to the success of root canal treatment. This study compared the effectiveness of smear layer removal between 17% EDTA and 6.25% pineap-ple peel extract (PPE) (Ananas comosus L. Merr). A total of 32 upper premolars with intact crowns and root canals were divided into two groups: 17% EDTA and 6.25% PPE. The samples were prepared using the crown-down pressureless technique, rinsed according to their respective groups, and analysed for smear layer removal using SEM at 1000x magnification at the apical third of the root canal. A t-test revealed a significant difference in the effectiveness of smear layer removal between the two groups. Pineapple peel extract demonstrated superior performance in removing the smear layer at the apical third com-pared with 17% EDTA. It was concluded that 6.25% PPE is a promising alternative to 17% EDTA for root canal irrigation.
Emergency management of maxillofacial infections: a retrospective evaluation of treatment protocols and patient outcomes in dental practices: Penanganan darurat infeksi maksilofasial: evaluasi retrospektif terhadap protokol pengobatan dan hasil perawatan di praktik kedokteran gigi Adhe Ismunandar
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1077

Abstract

Maxillofacial infections pose significant challenges in the management of dental emergencies, particularly when accompanied by airway obstruction and se-vere bleeding. Rapid and effective management is crucial for improving treatment outcomes in life-threatening situations. This article investigates the proto-cols followed by dental professionals in managing maxillofacial infections, focusing on airway management, infection control, and facial trauma stabilisation, as well as their outcomes. This retrospective observational study analysed data from 50 dental professionals working in various healthcare settings. Treatment me-thods, including the Advanced Trauma Life Support (ATLS) protocol, imaging techniques, and infection control measures, were evaluated for their effective-ness in stabilising patients. A total of 90% of patients experienced airway obstruction requiring immediate intervention, and 80% had infections in the subman-dibular and sublingual spaces. The ATLS protocol was applied in all cases, focusing on airway management and infection control; a high success rate of 85% was achieved in stabilisation, whilst 70% of cases required referral to a specialist care facility for surgical intervention. It was concluded that effective mana-gement of maxillofacial infections requires timely airway intervention and infection control measures. The implementation of the ATLS protocol at all levels of care is crucial for successful patient outcomes.
The potential of oral microneedle patches as a delivery system for golden sea cucumber collagen and snakehead fish albumin for oral mucosal wound healing: Potensi oral microneedle patch sebagai sistem penghantaran kolagen teripang emas dan albumin ikan gabus untuk penyembuhan luka mukosa mulut Laras Panca Sakti; St Nabilah Kaltsum; Yuni Sulistiowati Maryono; Nisrina Ekayani Nasrun
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1082

Abstract

This review analyses the potential for synergistic integration between golden sea cucumber (Stichopus hermanni) collagen and snakehead fish (Channa striata) albumin via a mucoadhesive oral microneedle patch delivery system to accelerate wound healing. This study employs a comprehensive literature review, exploring the biology of mucosal wound healing, the biochemical profiles of the golden sea cucumber and snakehead fish components, and the mechanism of microneedle technology. Type I collagen from the golden sea cucumber acts as a structural scaffold and a provider of proliferative signals through its in-teraction with integrins. Meanwhile, catfish albumin functions as an anti-inflammatory agent, an osmotic pressure balancer, and a provider of essential me-tabolic nutrients (such as zinc and amino acids) that support the proliferation phase. The use of dissolving microneedle technology enables precise, pain-free penetration through the epithelial barrier, whilst delivering the effects of percutaneous collagen induction therapy via mechanical microtrauma that sti-mulates the healing cascade. The design of a double-layered hybrid patch with a mucoadhesive layer has been shown to maintain drug retention in the moist oral cavity environment. The integration of S.hermanni collagen and C.striata albumin into the oral microneedle system promises a revolutionary therapeutic approach to the management of mucosal wounds through the simultaneous modulation of the NF-?B and TGF-?1 signalling pathways.
Antibacterial activity test of papaya seed extract (Carica papaya L.) as an irrigation agent against Prevotella intermedia: Uji daya hambat ekstrak biji pepaya (Carica papaya L.) sebagai bahan irigasi terhadap bakteri Prevotella intermedia Alifa Nailah Suni; Indrya Kirana Mattulada; Syamsiah Syam; Nur Asmah; Kurniaty Pamewa
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1103

Abstract

Root canal infections are one of the main problems in endodontics, largely caused by Gram-negative anaerobic bacteria, like Prevotella intermedia, which is frequently found in necrotic pulp, periapical abscesses and chronic root canal infections. Root canal irrigation is essential for eliminating microorganisms; however, conventional agents such as sodium hypochlorite have several side effects, necessitating the use of safe and effective natural, one of which is pa-paya seed extract (Carica papaya L). This study investigated whether papaya seed extract, when used as an irrigant, can inhibit the growth of P.intermedia. This laboratory experimental study, employing a post-test control design, utilised samples of 5%, 20% and 30% papaya seed extract, alongside 2.5% sodium hypochlorite and distilled water as the control. The disc diffusion method was employed to assess inhibitory activity on Mueller-Hinton agar media inoculated with P.intermedia, with five replicates for each treatment. Data were analysed using one-way ANOVA and LSD post hoc tests. Pa-paya seed extract at all concentrations exhibited inhibitory activity against the growth of P.intermedia, the greatest was observed at the 15% concentration, followed by 10% and 5% (p<0.05). It is concluded that papaya seed extract effectively inhibits the growth of P.intermedia and has the potential to be used as an alternative irriga-gation agent in root canal treatment.
Utilization of gelatin from fish skin as a scaffold for gingival tissue regeneration: Pemanfaatan gelatin dari kulit ikan sebagai scaffold regenerasi jaringan gingiva Baharuddin M. Ranggang; Herdini Isnaeni Haer; Sitti Zahra Zafira; Khairunnisa Nur Rizqi Ababil; Stefanie Amelia Intan Hutahean; Shela Nurasmah
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1153

Abstract

Periodontal disease is a highly prevalent oral health problem that often leads to tooth loss. Conventional therapies such as scaling and root planing only halt disease progression but fail to regenerate lost tissue. Tissue engineering approaches offer a solution by utilizing scaffolds as 3D frameworks to support cell adhesion, proliferation, and differentiation. Fish skin gelatin is a promising alternative biomaterial because it is biocompatible, biodegradable, hydrophilic, free from zoonotic risks, and ethically and religiously acceptable. Various in vitro and in vivo studies have shown that fish gelatin-based scaffolds can increase gi-ngival fibroblast viability, type I collagen expression, and angiogenesis, as well as accelerate the epithelialization process with minimal inflammatory response. Chemical modifications such as crosslinking and 3D printing technology have been shown to improve mechanical stability and optimize the porous proper-ties of the scaffold. Thus, fish skin gelatin has great potential as a scaffold for gingival tissue regeneration.
The potential of Stichopus hermanii as a marine biomaterial for bone regeneration in dentistry: Potensi Stichopus hermanii sebagai biomaterial laut dalam regenerasi tulang pada bidang kedokteran gigi Asmawati Amin; Audrey Nathalie Alicyandrina Sitindaon; Ade Lola Zafira
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1155

Abstract

This systematic review aims to evaluate the potential of Stichopus hermanii as a natural biomaterial for bone regeneration. A systematic literature search was conducted via PubMed, Scopus, ScienceDirect and Google Scholar using keywords related to S.hermanii, bone regeneration, socket healing and biomaterials. Article selection followed the PICOS framework, encompassing both in vitro and in vivo studies. S.hermanii holds great potential as a natural biomaterial to support alveolar bone regeneration due to its osteoconductive and osteoinductive properties. Bioactive components such as collagen, glycosaminoglycans, chondroitin sulphate and essential minerals have been shown to enhance new bone formation, increase the number of osteoblasts, suppress osteoclast activity and accelerate the healing process, particularly when used in conjunction with scaffolds such as collagen or hydroxyapatite. It is concluded that S.hermanii has potential as a natural, osteoconductive and bioactive biomaterial to support alveolar bone regeneration, particularly in applications following tooth extraction, periodontal therapy and implant procedures.
Marine-derived chitosan composites in restorative dentistry: antibacterial and mechanical properties: Komposit kitosan yang berasal dari laut dalam kedokteran gigi restoratif: sifat antibakteri dan mekanisnya Alqarama Mahardhika Thalib; Asmawati Amin; Bahruddin Thalib; Nurul Zulhijjah; Lenni Indriani
Makassar Dental Journal Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v15i2.1159

Abstract

Conventional composite resins often show limited antibacterial activity and are susceptible to degradation, potentially leading to secondary caries. Chitosan, a natural polysaccharide, exhibits biocompatible, biodegradable, and antibacterial characteristics, offering potential improvement in composite resin perfor-mance. This review evaluates the effect of chitosan incorporation on the mechanical and antibacterial properties of composite restorations. A systematic re-view following PRISMA guidelines was conducted using PubMed, ScienceDirect, and Elsevier databases (2015-2025). Inclusion criteria covered in vitro and in vivo studies analyzing chitosan-modified composite resins. Five eligible studies were reviewed based on chitosan concentration, resin type, and outcomes. Chitosan (0.1-2%) enhanced hardness, fracture resistance, and surface stability while providing notable antibacterial activity against S.mutans. Antibacte-rial effects increased up to 2-5%, though higher concentrations (>5%) could reduce some mechanical strength. It is concluded that marine chitosan appears to be an effective additive for restorative composites, improving antibacterial properties and mechanical stability without compromising adhesion. Further cli-nical trials are needed to validate its long-term benefits and optimal concentration for dental applications.

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