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Andika Aliviameita
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Medicra (Journal of Medical Laboratory Science/Technology)
Published by Universitas Muhammadiyah Sidoarjo
ISSN : 25807730     EISSN : 25807730     DOI : https://doi.org/10.21070/medicra
Core Subject : Health,
Health Professions Public Health
Focus : to facilitate scholar, researchers, and lecturers for publishing the original articles of review articles. Scope : Medicra publishes research articles in the field of “medical laboratory (science/technology)” with the following scope: Clinic Chemical Hematology Microbiology Parasitology Immunology Food and beverage analysis Chemical Molecular Diagnostics Toxicology Cytology Histology Epidemiology Laboratory Management Laboratory Quality Control
Arjuna Subject : Profesi Kesehatan - Teknologi Laboratorium Medis
Articles 10 Documents
 1 
Search results for , issue "Vol. 4 No. 1 (2021): July" : 10 Documents clear
Lethal Efficacy of Banana Leaves Extract (Musa paradisiaca L.) Against Aedes aegypti Larvae: Daya Bunuh Ekstrak Daun Pisang (Musa paradisiaca L.) Terhadap Larva Aedes aegypti Karima, Wihdatul; Ardiansyah, Syahrul
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.881

Abstract

Indonesia has a potential to be exposed to the threat of dengue hemorrhagic fever with the point vector, the Aedes aegypti mosquito, so development need to be stopped. The use of synthetic larvicides in eradicating mosquito larvae can cause environmental pollution. To reduce it, an alternative is needed using plant larvacides with banana leaf. Banana leaves are obtained from Candi Sidoarjo. Ethanol extract of banana leaf contains tannin compounds, alkaloids, terpenoids, saponins, and flavonoids which can be used as larvicides. This research was conducted to determine the toxic effects of banana leaf extract (Musa paradisiaca L.) on the larvae of Aedes aegypti mosquito mortality. This research was conducted using the post test only the control group design with 6 treatment groups including control (aquades) and banana leaf extract concentrations of 1000 ppm, 2000 ppm, 3000 ppm, 4000 ppm, 5000 ppm. This study used third instar larvae, each test group countaining 20 larvae with 4 repetitions. That obtained were analyzed using data and probit tests. The results of this study that banana leaf extract has a toxic effect on Aedes aegypti mosquito larvae with LC50 at a concentration of 4638 ppm.
Comparison of Erythrocyte Index Values of Venous and Capillary Blood : Perbandingan Nilai Indeks Eritrosit pada Darah Vena dan Kapiler Wahyuni, Nining; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.895

Abstract

Erythrocyte index is a laboratory examination in establishing the diagnosis of anemia including MCV, MCH, and MCHC obtained from the calculation of hemoglobin, hematocrit, and the number of erythrocytes. This study aims to determine differences in the value of the erythrocyte index in venous and capillary blood. This research is an experimental laboratory study, the sample was examined at the Ar-Rahmah Tulangan Clinic in Sidoarjo in March 2020. The examination method used in this study was automatic. Blood samples were taken from 30 patients so that a total of 60 blood samples (30 venous blood and 30 capillary blood). The results of the examination with the Mann Withney test showed a significant difference in the value of MCV (p = 0.001) and MCH (p = 0.001) and there was no difference in the value of MCHC (p = 0.251).
The Potential of Mango (Mangifera infica L.) Peel of Apple Varieties By Infusion And Maceration In Inhibiting Pseudomonas aeruginosa And Propionibacterium acnes: Potensi Kulit Mangga (Mangifera infica L.) Varietas Apel Secara Infusa Dan Maserasi Dalam Menghambat Bakteri Pseudomonas aeruginosa dan Propionibacterium acnes Rahmawati, Vifin Putri; Rini, Chylen Setiyo
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.904

Abstract

Plants have many chemical components. The use of natural ingredients as an alternative treatment in dealing with diseases, especially acne. One of them is mango (Mangifera indica L.) varieties of apples obtained at the Larangan Main Market in Sidoarjo. This study aims to determine the potential of infusion and maceration of mango skin varieties in inhibiting Pseudomonas aeruginosa and Propionibactrium acne at various concentrations. This antibacterial potential test was carried out using the diffusion method of the wells. The antibacterial potential is characterized by the formation of a clear zone around the well called the inhibition zone. This study uses 10 concentrations namely 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90% and 100% and Clindamycin as positive control and aquades as negative control. Based on the results of the Two Way ANOVA test data obtained were not normally distributed, therefore a comparison test was performed using the Kruskal-Wallis test with a sign value (α <0.05). This showed that there were significant differences in the use of various concentrations. The maceration extract concentration of 100% is the best concentration to form a zone of inhibition against P. aeruginosa of 17.9 mm and P. acne bacteria of 13.2 mm. The results of the infusion extract concentration did not form inhibitory zones in both of P. aeruginosa and P. acnes.
The Activities Of Combination Citrus hystrix Peel Extract and Carica papaya Leaves Extract Against Candida albicans and Escherichia coli : Aktivitas Campuran Ekstrak Kulit Citrus hystrix dan Ekstrak Daun Carica papaya Terhadap Candida albicans dan Escherichia coli Anitasari, Septarini Dian; Sari, Dwi Nur Rikhma
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1359

Abstract

Citrus hystrix Peel Extract and Carica papaya Leaves Extract contain several active components that can be used as antimicrobial compounds. The aim was to test a mixture of extracts from Citrus hystrix peel and Carica papaya leaves as growth inhibiting compounds for Candida albicans and Escherichia coli. This study used 4 levels of treatment, namely a combination of papaya leaves extract and orange fruit peel at concentrations of 0%, 25%, 50%, 75% and 100%. The research data were in the form of the diameter of the growth inhibition of Escherichia coli and Candida fungi, which were analyzed using the Kruskall-Wallis test at 5% confidence level and 5% Duncan's test. showed a significant difference between treatments, but the concentration of 100% showed better results to inhibit Escherichia coli (1.58 ± 0.28 d) and the growth of Candida albicans (1.53 ± 0.57b) compared to controls and other concentrations.
Phytochemical Screening of White Turi (Sesbania grandiflora (L.) Pers.) Leaves Extract in Various Extraction Methods: Skrining Fitokimia Ekstrak Daun Turi Putih (Sesbania Grandiflora (L.) Pers.) pada Variasi Metode Ekstraksi Rohmah, Jamilatur; Saidi, Ida Agustini; Rofidah, Luthfiyah; Novitasari, Fia; Margareta, Frida Amelia
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1395

Abstract

One of the Fabaceae family that has potential as medicinal plant is the white Turi plant (Sesbania grandiflora (L.) Pers.).The purpose of this study was to determine the content of secondary metabolites which can be extracted using a various extraction methods.The extraction method used are digestion, percolation, reflux, soxhlet, infusion, and decoction extraction. The Turi plants used come from Mojosari, Mojokerto.The results of the initial phytochemical screening of white Turi leaf extract (Sesbania grandiflora (L.) Pers.) Were extracts in six extraction methods containing alkaloids, saponins and tannins.In extracts using the digestion, soxhlet, and reflux method containing steroids.Meanwhile, the four extracts from the digestion, percolation, soxhlet, and reflux methods contain phenolic.And the infusion and decoction method extracts containing flavonoids and triterpenoids. The similarity of the phytochemical test results for each extract but with different intensity results.
A Case Report :Alprazolam Therapy in A Dextra Fronto-Parietal Meningioma Patient With Anxiety Disorders: Efektivitas Alprazolam Pada Pasien Meningioma Fronto-Parietal Dextra Dengan Gangguan Cemas Wibowo, Prajogo; Utami, Prawesty Diah
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1409

Abstract

Meningiomas in the frontoparietal lobe may cause anxiety disorders and panic attacks. While alprazolam is one of the most widely used medications for anxiety disorders, long-term use may result in adverse side effects (withdrawal and rebound effects). This case study aims to describe the efficacy of long-term alprazolam administration in patients with meningiomas for regulating anxiety disorders. Case report :The asymmetrical face is the primary concern of a 65-year-old female when she is anxious. The results of the physical assessment and laboratory tests are within normal ranges. However, The HARS procedure showed moderate anxiety, and the CT scan revealed a meningioma in the right frontoparietal lobe. To regulate patient anxiety disorders, doctors give alprazolam 0.5 mg per day single dose for 4 months and tapering off for 3 months. Conclusion: Long-term administration of alprazolam in these patients can reduce the patient's anxiety disorder without causing withdrawal or rebound effects. A low dosage of alprazolam, a mild level of anxiety illness, and a slow tapering off phase were factors that contributed to the effectiveness of alprazolam treatment to suppress anxiety symptoms in this situation.
Comparison of Smoking Habits and Coffee Consumption In Adolescents Against Hemoglobin Levels In Mojoroto Kediri City: Perbandingan Kebiasaan Merokok dan Mengkonsumsi Kopi Pada Remaja Terhadap Kadar Hemoglobin Di Mojoroto Kota Kediri Purnadianti, Mely; Ermawati, Nita; Berlian , Rere Nadhif
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1422

Abstract

Cigarettes are processed tobacco using or without addictive substances. The increasing of hemoglobin in smokers due to the content of carbon monoxide causes hemolysis of erythrocytes that is stronger than oxygen, so that hemoglobin increases. In addition to smoking, the society's habit is about coffee consumption. Coffee is a beverage with high polyphenols. The decreasing of hemoglobin occurs when drinking too much coffee. It will reduce the absorption of iron and erythrocytes ability to deliver oxygen from the lungs to all tissues in the body, therefore the hemoglobin will decrease. One of the laboratory tests that is used to see hemoglobin levels in smokers and coffee consumers is the POCT method of hemoglobin examination. The purpose of this study was to analyze the comparison of the effect between smoking and coffee consumption on hemoglobin levels in adolescents on the streets of Mejenan Gang 3 Mojoroto Kediri. The method that is used in this research is comparative study and the sampling technique that is used purposive sampling with a sample size of 40 respondents. The results show that 10 adolescents (50%) had abnormal hemoglobin levels and 10 adolescents (50%) had normal hemoglobin levels. 5 teenagers (25%) had abnormal hemoglobin levels and 15 (75%) normal hemoglobin levels. Based on statistical tests, the results obtain p-value 0.423 and> 0.05. So it can be concluded that there is a moderate effect between cigarettes and coffee on hemoglobin levels in adolescents on Mejenan Street Gang 3 Mojoroto Kediri.
Epidemiological Study of Dengue Hemorrhagic Fever (DHF) With Increased Incidence of Serum Glutamic Pyruvic Transaminase (SGPT) Levels at Aura Syifa Hospital Kediri: Studi Epidemiologi Demam Berdarah Dengue (DBD) dengan Kejadian peningkatan kadar Serum Glutamic Pyruvic Transaminase (SGPT) di Rumah Sakit Aura Syifa Kediri Kurniasari, Mia Ashari; Nurziah, Anggit Saputri Okta
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1428

Abstract

Dengue fever virus is an infectious disease that can infect others if bitten by Aedes aegypti mosquito. The virus has the potential to attack cells in the hepar organs so that the hepar is inflamed, swollen, and liver function is disrupted, and there is severe bleeding. The increase in transaminase enzymes as well as hepatomegaly is a frequent sign in dbd sufferers, thus reinforcing the notion that the course of dengue hemorrhagic fever (DHF) disease can affect hepar or liver organs. The presence of such events will increase the level of Serum Glutamic Pyruvic Transaminase (SGPT) and Serum Glutamic Oxaloacetic Transaminase (SGOT) in dengue fever patients. The purpose of this study is to find out the epidemiological study of Dengue dengue fever with the increase in SGPT and SGOT levels in dengue fever patients at Aura Syifa Kediri Hospital. This research method uses descriptive research design and total sampling technique for 1 month. Samples obtained for 1 month amounted to 15 samples. The results showed that from a sample of 15 respondents as many as 3 samples (20%) for high SGPT levels above normal and normal results as many as 12 samples (80%). The conclusion of this study shows that the value of SGPT levels has increased by 20% and is still above normal, but still have to be alert to small values.
Efficacy of Aloe vera Gel on the Excision Wound Healing in Sprague dawley Rats: Efikasi Gel Lidah Buaya (Aloe vera) terhadap Kesembuhan Luka Eksisi pada Tikus Sprague dawley Palgunadi, Bagus Uda; Rahayu, Asih; Prakoso, Yos Adi
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1432

Abstract

Wound is a pathological processes in all living things. Wound includes the overlapping mechanisms. The failure in wound healing causes infection. This study aimed to analyze the efficacy of Aloe vera gel in excisionwound on the rat’s back. This study used 18 male, Sprague Dawley rats, and they were induced excision wound on the back. The rats were separated into 3 groups, K1 = control, K2 = treated with betadin gel, K3 = treated with Aloe vera gel. The therapy was given twice a day for 7 days. The wound measurement was observed in day 3 and 7. The data were analyzed using SPSS. The result showed that Aloe vera gel potentially promote wound healing through the decrease microscopical condition of wound, re-epithelialization, and deposition of collagen better than in group K1 and K2 (p≤0.05). In conclusion, Aloe vera gel promote excision wound healing in Sprague Dawley rats.
The Effect Of Using Personal Protection Equipment (PPE), Mileage, And Smoking Habits On Hair Lead (Pb) Levels: Pengaruh Penggunaan Alat Pelindung Diri (APD), Jarak Tempuh Dan Kebiasaan Merokok Terhadap Kadar Timbal (Pb) Rambut Wulandari, Devyana Dyah; Rohmah, Wardah; Nidianti, Ersalina; Santoso, Andreas Putro Ragil; Andini, Ary
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1435

Abstract

Street sweepers, traffic officers, roadside sellers and motorcyclists, including students are subjects who are vulnerable to exposure to vehicle fumes. One of the air pollution generated from motor vehicle fumes is lead (Pb) which is toxic to humans and is accumulative. This study aimed to analyze the relationship between characteristic factors and lead levels in hair using the Atomic Absorption Spectroscopy (AAS) method. Respondents in this study were 32 male university students. The results showed a significance value of 0.274 (p> 0.05) on the parameter of PPE use, 0.049 (p <0.05) on the mileage parameter, and 0.576 (p> 0.05) on the smoking habit parameter. So it can be concluded that there is no effect of the use of PPE and smoking habits on hair lead levels and there is an effect of mileage on hair lead levels in student respondents.

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