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Budapest International Research in Exact Sciences (BirEx Journal)
Published by Budapest International Research and Critics University Journal
ISSN : 26557835     EISSN : 26557827     DOI : DOI: https://doi.org/10.33258/birex
Core Subject : Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Physics Transportation
Budapest International Research in Exact Sciences (BirEx-Journal) is a peer reviewed journal published in January, April, July, October welcome research paper in Medical Science, Agriculture Science, Biological Science, Engineering Science and other related areas and it is published in both online and printed version
Arjuna Subject : Ilmu Material (semua kategori) - Ilmu Material (Lain-Lain)
Articles 276 Documents
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Influence Before and After Early Mobilization of Changes in Pain Levels in Sectio Cesarea Postoperative Clients at Royal Prima Hospital in 2020 Ma Hongjun; Florenly Florenly; Liena Liena; Fioni Fioni
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.3052

Abstract

Sectio Caesarea is artificial labor in which the fetus is born through an incision in the front wall of the abdomen and the uterine wall. The number of Sectio Caesarea patients in Indonesia has exceeded the recommended threshold of the Department of Health > 20%. Surgery can cause postoperative pain in the client, this pain is usually felt 12 to 36 hours after surgery. One of the management of non-famakological treatment of post-section caesarean section pain treatment is early mobilization. Early mobilization aims to accelerate wound healing, improve circulation, and prevent venous static. The purpose of this study was to determine the influence before and after early mobilization of changes in pain levels in postoperative clients of sectio cesarea. This type of research is descriptively correlational, One Group Pretest-Postest, conducted at RSU Royal Prima Medan Petisah, North Sumatra from September to November 2020. The study population ± 43 people. The number of samples using the formula Slovin, so 36 samples were obtained. The selection of samples with non-probability sampling is consecutive sampling. Analysis of data, with a univariate, bivariate, meaningful limit of 0.05 with t-dependent test (paired t-test).The results, the change in pain level score of the pre-test test results of the mean value 3.22, at the time of the post-test test the mean value is 2.17. So the result of the value Z = -6,128 then p-value as much as 0.000 < 0.05 so that it was concluded Ho was rejected and Ha received. Concluded there is an influence of early mobilization of pain changes in postoperative clients sectio caesarea in the room of RSU Royal Prima in 2020.
Carbon Estimation in Three-Year-Old Ex-Field Shrub Vegetation in Ujoh Bilang Village Mahakam Ulu Regency, East Kalimantan Province Zikri Azham; Steffani Huring; Hj. Maya Preva Biantari; Ismail Ismail
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3982

Abstract

Carbon Estimation in Three-Year-Old Ex-Field Shrub Vegetation in Ujoh Bilang Village, Mahakam Ulu Regency, East Kalimantan Province. The purpose of this study was to estimate the carbon content of shrub vegetation that had been abandoned for three years in Ujoh Bilang Village, Mahakam Ulu Regency. Vegetation sample data were collected according to the growth rate, namely in plots measuring 20 x 100 m, sub plots 10 x 50 m and research plots 1 x 1 m, the samples were plant vegetation, litter, necromass and dead wood. cVegetation samples were dried in an oven. The data were processed and calculated using the biomass formula and converted to carbon content per hectare. The results obtained from this study are the carbon content of dead wood nekormas of 12 tons/hectare, understorey vegetation of 0.609 tons/hectare, litter of 0.604 tons/hectare, and the total carbon content of shrub vegetation that has been abandoned for three years is 13,213 tons. /hectare.
Effectiveness of Turmeric Ethanol Extract Cream Preparation (Curcuma Longa) in Speeding up Wound Healing in Male Wistar Rats Wang Ling; Florenly Florenly; Liena Liena; Dewi Riastawaty Purba
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3472

Abstract

Injury is the loss or damage of some body tissues, due to a factor that interferes with the body's protective system. The results of several studies state turmeric rhizome extract is effective in wound healing. This study aims to find out the effect of turmeric extract (Curcuma longa) on wound healing in white rats. This type of research is experimental with the approach of Pre-test and Post-test group only control design, conducted November to December 2020. The samples used were turmeric rhizomes (Curcuma Longa) and male white rats. Determination of the size of the sample according to Federer's formula, so that the number of samples as many as 25 mice, the division of 4 treatment groups and 1 control group. The results of the study from the Anova test obtained a Sig value. Calculate 0.000 while sig value (α) is 0.05 which means sig value. Count sig < (α). This means that there is a real influence of the administration of turmeric extract (Curcuma Longa) on the healing of sores in mice. Turmeric ethanol extract (Curcuma Longa) has several bioactive compounds such as alkaloids, flavonoids, saponins, and tannins that play a role in wound healing. The optimum concentration of turmeric ethanol extract (Curcuma Longa) that can cure sores in white rats is 5%. The highest percentage of cures on k-14 days was in the positive control (Bioplacenton®) which was 95% and followed by extract 5% v/ v with a cure percentage of 90%. The creamy preparation of turmeric ethanol extract (Curcuma Longa) has an ability that is close to Bioplacenton® in healing wounds in mice.
Promotion of Papua “Merbau” Iron Wood (Eusideroxylon Zwagerii) through in-Vitro Tissue Culture Roy Marthen Rahanra; Muhammad Imron; Dwi Yarmalinda
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3484

Abstract

Papua's ironwood comes from the merbau plant that inhabits the forests of Papua, one of which is in the Yapen Islands Regency, Serui City. In conventional cultivating ironwood for commercial purposes, there are various problems. When using powder and soil, a lot of sawdust is needed. In addition, the time required for planting seeds to produce shoots that are ready to be planted in the field takes a very long time of about 9-12 months. The first step in the cultivation of merbau tissue culture is to find the right formula for growth regulators. Auxins and cytokines are the right steps to stimulate merbau wood growth. It seems that the role of auxin (IAA) and cytokinin (BAP) in Murashige and Skoog media on Merbau Wood using cotyledon and meristem explants with good concentrations for shoot and plantlet formation was 1.0 mg/l IAA and 5, 0 mg/l from the latest research using hormones including NAA, Chitin and BAP in Merbau (Eusideroxylon zwageri) wood culture. NAA concentration 1 mg/l (A4B5) formed shoots and callus, A4B1 (NAA 1 mg/l; BAP 0 mg/l) resulted in organogenesis and NAA concentration 0.2 mg/l without cytokinins (A2B1) produced multiple shoots. The interaction of the combination of auxin NAA 1 mg/l with BAP 0.6 mg/l (A4B7) gave the best response in embryosomatic formation in implanted explants. While the interaction of NAA 0.2 mg/l with Kinetic 2 mg/l (A3B3) resulted in shoots and callus. The interaction of the combination of auxin NAA 1 mg/l with BAP 0.6 mg/l (A4B7) gave the best response in embryosomatic formation in implanted explants. While the interaction of NAA 0.2 mg/l with Kinetic 2 mg/l (A3B3) resulted in shoots and callus. The interaction of the combination of auxin NAA 1 mg/l with BAP 0.6 mg/l (A4B7) gave the best response in embryosomatic formation in implanted explants. While the interaction of NAA 0.2 mg/l with Kinetic 2 mg/l (A3B3) resulted in shoots and callus.
Effect of Turmeric Ethanol Extract Ointment (Curcuma Longa) on the Healing of Grade II Burns in Wistar Rats (Rattus Norvegicus) Ji Junfeng; Florenly Florenly; Johannes Bastira Ginting; Fioni Fioni
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.3053

Abstract

Burns is still a choir for clinical nurses as severe burns have led to high postburn morbidity. In Indonesia, the death rate from burns is still high at about 40%, mainly caused by severe burns. Curcuma longa herbal products have several such antioxidants, anti-inflammatory, anti-cancer. The purpose of this study was to find out the phytochemical content and effect of turmeric Ethanol Extract Ointment (Curcuma longa Linn) in curing grade II burns in Wistar rats (Rattus norvegicus). This study is an experimental study with a pre and post-test control group design approach. This research was conducted at Riwandi Pet Shop and Animal House and Laboratoirum Taxonomy of Plants, Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), the University of North Sumatra in February-March 2021. The study sampled 20 turmeric rhizomes and male Wistar rats (Rattus norvegicus) divided into 4 treatment groups. Independent variables of topical formulation (base ointment, nebacetin ointment®, Turmeric Ethanol Extract Ointment (Curcuma longa) 5% and Turmeric Ethanol Extract Ointment (Curcuma longa) 10%, as well as independent variables that include wound contraction and epithelial period. The results of phytochemical screening in turmeric found phytochemicals in the form of flavonoids, alkaloids, and tannins. The results of the study obtained significant differences in the epithelial period of the standard group, turmeric ointment 5% and 10% against the control group. However, in the turmeric ointment group and the standard group, there was no difference in epithelialization periods. This is evident from the value P < 0.05 (Value P = 0.028). Where the wound contraction rate of turmeric ointment is 10% better than nebacetin ointment as standard. But in both turmeric ointments, both 5% and 10% and nebacetin ointment as standard did not show significant differences in the parameters of the epithelial period.
Effect of Planting Media Composition and Probiotics of Effective Microorganisme 4 Application on the Production of Oyster Mushroom (Pleurotus Ostreatus) Abdul Rahmi; Noor Jannah; Rudy Apriyanto
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3994

Abstract

The purpose of this research are:  (1) to determine the effect of planting media composition and probiotics effective microorganisme 4 (EM4) application as well as its interaction on the production of oyster mushroom, and (2) to find the proper of planting media composition and the probiotics EM4 concentration to obtain the optimal production of oyster mushrooms. The research conducted at Barong Tongkok Village, Barong Tongkok Sub District of West Kutai Regency.  It began from April to November 2018 commencing from baglog preparation until the end of observation. The research used a completely randomized design (CRD) factorial 4 x 4 with 5 replications.  The first factor was the composition of the planting media (M) with 4 levels of treatment, namely the percentage of different composition of mushroom growing media, they are sawdust: bran: cornflour: lime: SP-36; namely m1 = 75:21:1:2:1; m2 = 80:17:1:2:0; m3 = 85:12:0.5:1.5:1; and m4 = 90:8:0.5:1.5:0.  The second factor was the application of probiotics EM4 with 4 levels of treatment, namely: p0 = no probiotics, p1 = 5 ml l-1 water; p2 = 10 ml l-1 water, and p3 = 15 ml l-1 water. The research results revealed that : (1) the mushroom planting media composition affected very significantly on the mushroom mycelium growth (at 14, 18, 22, 26, 30, 34, 38 and 42 days after inoculation (HSI), age at harvest, mushroom production, and biology efficiency ratio (REB). The highest production of oyster mushrooms attained at the m1 treatment, namely 533.0 g baglog-1; in reverse, the lowest one attained at the m4 treatment, namely 406.3 g baglog-1;  (2) the application of EM4 on the mushroom growing media affected significantly to very significantly affect on the mushroom mycelium growth (at 18, 38 and 42 HSI), age at harvest, mushroom production and REB, but it was not significantly affect on the mushroom mycelium growth at 14, 22, 26 and 30 HIS.  The highest production of oyster mushrooms attained at the p2 treatment, namely 562.0 g baglog-1, meanwhile the lowest one was attained at the p0 treatment with only 406.3 g baglog-1; (3) the interaction effect between the mushroom growing media and EM4 application was very significantly effect on the REB, but it was not significant on the mushroom mycelium growth at all days observed, age at harvest, and mushroom production.
Effectiveness of Ethanol Extract Mangosteen Peel (Garcinia Mangostana L.) in Accelerating Post-Tooth Extraction Healing in Wistar Rats Dong Qian; Florenly Florenly; Liena Liena; Dewi Riastawaty Purba
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3473

Abstract

Tooth extraction will cause a wound in the form of alveolar bone that opens in the oral cavity. Mangosteen peel has various pharmacological effects such as anti-inflammatory, antioxidant, antidiabetic, and antibacterial. The goal of this study was to find out the effectiveness of Mangosteen Peel Ethanol Extract (Garcinia mangostana L.) 45% with 90% in speeding up the healing time of post-tooth extraction wounds in Wistar rats. This type of research is an experimental laboratory with a post-test pattern only control group design. Conducted at the Laboratory of Pharmacology & Laboratory of Traditional Medicine Faculty of Pharmacy, University of North Sumatra January-March 2021. The animal is a male Wistar rat of 32 who is physically healthy. The size of the sample is determined by Federer's formula, the minimum sample size for each treatment is 16 rats. The results of the study that there is a significant relationship between the amount of fibroblast tissue per field of view in Wistar Rats after tooth extraction with the administration of mangosteen peel (Garcinia mangostana L.) with a concentration of 45% and mangosteen peel (Garcinia mangostana L.) concentration 90%, p = 0.036 (p<0.05). Mangosteen skin extract (Garcinia mangostana L.) is 45% and 90% effective in speeding up wound healing time after extraction of rat teeth Wistar. Mangosteen skin extract (Garcinia mangostana L.) is 90% more effective than turmeric extract (Curcuma longa) 45% in speeding up wound healing time post-extraction of rat teeth Wistar due to the flavonoid content in mangosteen skin extract (Garcinia mangostana L.) 90% which helps accelerate wound healing higher than skin extract Mangosteen (Garcinia mangostana L.) 45%. 
The Effect of Probiotic Giving on Body Size Broiler Chicken Aged 2-4 Weeks Rusli Badaruddin; La Ode Nafiu; Muhammad Amrullah Pagala; La Ode Muh Munadi
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3537

Abstract

The study aimed to determine the effect of giving different probiotics to the growth rate of several body parts of broiler chickens such as chest circumference, femur length, tibia length, and body length at 2-4 weeks of age with 100 MB 202 platinum strain using BP 11 commercial feed, probiotic supplements. Liquid organics, Lacto probiotics, and local probiotics (tape yeast). The research method used a completely randomized design (CRD) then the data obtained were analyzed employing variance (ANOVA) and if there was a significant effect, it was continued with the Duncan Multiple Range Test (DMRT). The results of the analysis showed that the administration of tape yeast in broiler drinking water showed a significant effect (p<0.05) on the increase in chest circumference, femur length, and body length which was greater than liquid organic probiotics and lacto.
Analysis of Grade II Burns Healing from Andaliman Fruit Ethanol Extract Ointment (Zanthoxylum Acanthopodium Dc.) in Wistar Rats (Rattus Norvegicus) Li Sha; Florenly Florenly; Johannes Bastira Ginting; Fioni Fioni
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.3054

Abstract

The prevalence of injuries has increased every year, from riskesdas results data in 2013 reported that burns are the sixth cause of accidental injuries with a prevalence of 0.7 percent of the Indonesian population. Andaliman fruit extract with various phytochemicals has active physiological activity as a potential antioxidant and antimicrobial. The study aims to explore the wound healing effects of andaliman fruit ethanol extract. This study was an experimental study using 20 rats divided into 4 groups (Control, Standard, Essential Oil 10%, and Essential Oil 15%). Wound healing parameters are assessed through wound contraction and epithelial period. Samples of andaliman fruit used in this study were obtained from one of the traditional markets in the city of Medan. Essential oils are obtained from the hydrodistillation process. The results of the study showed significant differences in the epithelial period of the standard group, 10% and 15% in the control group. However, in the andaliman ointment group and the standard group, there was no difference in the epithelial period. This is evident from the value P < 0.05 (Value P = 0.029). The conclusion of the healing effects of burns possessed by andaliman ointment both 10% and 15% and nebacetin ointment as standard shows a significant difference. Where the wound contraction rate of your ointment is 15% better than nebacetin ointment as standard. But in both andaliman ointments, both 10% and 15% and nebacetin ointment as standard did not show significant differences in the parameters of the epithelial period.
Resilience State Security and the Role Sedative Agents in Military Pharmacy for State Defense in Future War Gilang Bhakti Nusantara; Syahrul Tuba
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 2 (2022): Budapest International Research in Exact Sciences, April
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i2.4590

Abstract

National defense is closely related to the role of an intelligence officer who is strong and capable of safeguarding the country's sovereignty. Intelligence covers many fields. One of those is medical intelligence. Mitragynine can be used as a sedative agent in a medical intelligence operation. To analyze a sedative agent in intelligent medical purposing of military aspect. This paper determines the role of Military Pharmacy in medical intelligence to support national defense using natural substances that contain a sedative agent. This research used narrative review method for this study obtained from Crossref, google scholar, PubMed, and Scopus range 2010 to 2021 in the English language, using the following terms: "National defense," "Medical intelligence," "Kratom" Mitragynine "Sedative agent" but we did not exclude out older works that were often cited and significant. Mitragynine binds to three types of receptors with varying affinities, with the highest affinity for μ, K, and δ-opioid receptors, which can be used as sedatives in medical intelligence to support national defense. Kratom is a plant endemic to Southeast Asia; this plant has a sedative effect at high doses. Kratom leaves contain thirty-seven alkaloid compounds. Both alkaloid compounds are Mitragynine and 7-hydroxymitragynine, both of which are included in the indole alkaloid compound, the main kratom compound. Plants that are used when facing the battlefield in maintaining national defense are very complex owned by the Indonesian state, that is the kratom plant which has a chance to strengthening people defense and security state facing of sixth generation war. This study needs to validate with more rigorous human clinical studies in the future.

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