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Budapest International Research in Exact Sciences (BirEx Journal)
Published by Budapest International Research and Critics University Journal
ISSN : 26557835     EISSN : 26557827     DOI : DOI: https://doi.org/10.33258/birex
Core Subject : Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Physics Transportation
Budapest International Research in Exact Sciences (BirEx-Journal) is a peer reviewed journal published in January, April, July, October welcome research paper in Medical Science, Agriculture Science, Biological Science, Engineering Science and other related areas and it is published in both online and printed version
Arjuna Subject : Ilmu Material (semua kategori) - Ilmu Material (Lain-Lain)
Articles 276 Documents
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Test the Cardioprotective Effectiveness of Turmeric Ethanol Extract (Curcuma Longa) in Doxorubicin-In-Rat Wistar (Rattus Norvegicus) Doxorubicin-Induced Males Wang Xiqin; Florenly Florenly; Liena Liena; Johannes Bastira
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2661

Abstract

Cardiotoxicity is mostly due to the use of chemotherapy drugs, with the class of anthracyclines drugs being 86.8. One of the most commonly used anthracyclines is doxorubicin. Turmeric with the scientific name Curcuma longa linn is one of the medicinal plants, the main compound is curcumin is considered able to reduce the risk of heart attack. The goal of this study tested the cardioprotective effectiveness of turmeric ethanol extract (curcuma longa linn.) in doxorubicin-induced male wistar (rattus norvegicus) mice. This type of research is experimental, in the Pharmacology Laboratory of the Faculty of Pharmacy, University of North Sumatra, and November 2020. Animals experimented on male wistar rats (Rattus norvegicus) weighing 150 - 200 grams. Data analysis, if (P > 0.05), continued with One Way ANOVA, but if (P <.05) followed by the Tukey HSD Post Hoc test to see real differences between treatments. If the distributed data is abnormal then the Kruskal-Wallis test results are used. Statistical test results, serum levels of CK–MB in the normal group have significant differences (p<0.05) with the negative control treatment group and the treatment group I, but do not have a significant difference (p>0.05) with the positive control group, treatment group II and the treatment group III. Concluding that turmeric ethanol extract has the ability to lower levels of biomarkers of heart damage namely CK-MB and LDH induced with doxorubicin, gradually increasing doses of turmeric ethanol extract can reduce the incidence of heart cell damage, which is most effective at doses of EEK 500 mg / kg BB. Turmeric ethanol extract has cardioprotective effects induced with doxorubicin. Administration of turmeric ethanol extract can repair heart organ tissue induced with doxorubicin based on histological picture of the heart. It is hoped that researchers will be able to conduct research on the toxic effects of giving turmeric ethanol extract to the hearts of mice conducted subchronically.
The Relation between the Characteristics of Parents and the Incidence of Stunting in Elementary School Children in the Working Area of the Air Beliti Health Center Dita Anggriani Lubis; Mohammad Zulkarnain; Risnawati Tanjung
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2633

Abstract

Stunting is a failure of growth and development experienced by children due to inadequate nutritional intake for a long time, recurrent infectious diseases, and inadequate psychosocial stimulation. The incidence of stunting is higher in rural areas than in urban areas. This study aims to analyze the relationship between maternal characteristics and the incidence of stunting in elementary school children in the Air Beliti Health Center working area. The study was conducted on elementary school children in the working area of the Air Beliti Health Center, Musi Rawas Regency. The design of this study used a cross-sectional design, with a total sample of 84 respondents who were taken randomly and met the inclusion criteria. Determination of stunting is based on anthropometric measurements, while the characteristics of parents are assessed using a questionnaire. Furthermore, the data were analyzed using Univariate, Bivariate, and Multivariate statistical tests. The results of anthropometric measurements showed that children who experienced stunting were 41 people, 48.8%. Based on the characteristics of the parents, it was found that 54.8% of fathers and 50% of mothers had low education, 65.5% of fathers and 75% of mothers worked as farmers, 58.3% of parents had low economic status, and 51.2% parents marry at a young age. There is a significant relationship between married age (p = 0.049), maternal education (0.029), and stunting incidence. Based on the multivariate test results, it was found that the most dominant factor related to the incidence of stunting was the age at marriage (p = 0.000; OR = 80.079). Parents who marry in their teens have a risk of 80,079 times having stunting children. Conclusion: adolescent marriage is associated with the incidence of stunting in elementary school children in the work area of the Air Beliti Health Center.
The Role of Quality Work of Life on Turnover Intention in Gading Pluit Hospital Kartika Lilisantosa; Rokiah Kusumapradja; Rina Anindita; Endang Ruswanti
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2645

Abstract

Turnover is a problem, often faced by an organization, including hospital organizations. High nurse turnover will disrupt hospital productivity, and increase hospital budgets to carry out recruitment, selection and training. Nurses might have the desire to move (Turnover Intention) which results in the nurse's decision to leave her job. Nurse turnover at Gading Pluit Hospital showed an increase from 9.3% (in 2019) to 15.5.0% (in 2020) with the largest percentage coming from inpatient nurses (86.7%). This study was conducted to identify the effect of Quality Work of Life (QWL), work stress, and organizational citizenship behavior (OCB) of inpatient nurses on turnover intention (TOI) at Gading Pluit Hospital. This research used mixed methods. Proof of the hypothesis using the causality method with SEM-PLS analysis then followed by qualitative method. The study was carried out from May to August 2021 using a saturated sample of 101 out of 107 nurses, followed by random inter-views with 5 nurses. The results showed that there was an influence of Quality of Work Life and Organizational Citizenship Behavior on Turnover Intention. OCB increased the effect of QWL in lowering TOI. Work stress with medium index has not affected OCB and TOI. Efforts to reduce Turnover Intention can be done by improving the Quality of Work Life and regulating the OCB behavior to in-crease a positive impact on nurses in carrying out their duties and functions. Interview results indicate the need to adjust the remuneration system, health insurance, and improve communication between management and nurses.
Analysis Sex Determination to Forensic Aspect Use Maxillary Sinus Measurement by CBCT: A Pilot Study Riki Kristanto; Eha Renwi Astuti; Ricardo Henrique Alves da Silva
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2764

Abstract

Analysis sex determination is an important to identification unknown person. CBCT scan can be used to analyzing a dimension in skeletal and for sex estimation when other methods are inconclusive using morphometric aspects, for example through maxillary sinuses can be performed the sex prediction. This study was conducted to estimate the size of the different dimensions of the maxillary sinus to sex determination of an individual by measuring the height, width, length and volume of the maxillary sinus using CBCT in Indonesia. The study of CBCT analysis scan from 20 subject (10 male and 10 female) shows that the potential high score parameter of p value is  0,00 < 0,05 on SI right, MSV right, AP left and MSV Left. It can be used to the prediction of sex determination. Binary logistic regression can be performed 85% from four parameter (SI right, MSV right, AP left and MSV Left) and the result more likely to male. Different result of discriminat function analysis showed the prediction to sex determination use maxillary sinus have percentage 80% to both group. The maxillary sinus measurements are valuable parameters for sex determination in forensic odontology, with a relatively good accuracy rate.
Exploration of the Analgesic and Antipyretic Effects of Mangosteen Peel Methanol Extract (Garcinia mangostana L) in Male Wistar Rats Jiang Fan; Florenly Florenly; Liena Liena; Fioni Fioni
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2634

Abstract

Analgetic-antipyretic is a compound that is often used to reduce pain and fever. A natural plant that has the potential as an antipyretic analgesic compound is mangosteen fruit (Garcinia mangostana L). This study aims to find out the analgesic and antipyretic effects of mangosteen peel methanol extract on male Wistar rats. This type of research is experimental, design Post-Test Only Control Group Design. The research was conducted at the Pharmaceutical Laboratory of the University of North Sumatra Medan, January - March 2021. The test was conducted using 25 mice divided into 5 groups. Data analysis uses SPSS test one-way ANOVA if the data does not distribute normal Kruskal-Wallis. The results of the study 5 hours after treatment, the body temperature of the mice experienced a significant change, the value of P < 0.05 (Value P = 0.004). Where the methanol extract group of mangosteen skin III showed the lowest body temperature 5 hours after treatment which was 36.14 ± 0.12oC and the methanol extract group Mangosteen-III skin also showed a significant difference to the control group that showed the highest body temperature of 37.36 ± 0.46oC. The least amount of geliat found in the mangosteen-III skin methanol extract group was 5.22 ± 1.91 and this number showed a significant difference with the mangosteen- I skin methanol extract group (12.81 ± 3.12) and the control group (11.10 ± 1.91). In conclusion, the results of mangosteen skin testing have antipyretic and antipyretic effects, found at 5 hours after treatment and the highest dose is 750 mg/ kgBB. Meanwhile, the results of the hematologic examination showed a significant decrease in line with the increase in the dose of mangosteen skin methanol extract given.
Initial Screening of Thyroid Function Test in Premature and Term Infants at General Hospital Dr. Zainoel Abidin Banda Aceh Pretyca Yudra Perdana; Dora Darussalam; Rusdi Andid; Mulya Safri; Syafruddin Haris; Nora Sovira
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2646

Abstract

Congenital hypothyroidism (CH) is the most common cause of mental retardation which can be prevented by early diagnosis and treatment. Premature infants have a higher risk of developing HK than term infants. Screening for CH in every newborn is important, however, in premature babies screening for CH using the TSH examination is often found to have normal levels in the first week of examination. This study is a cross sectional study where the research sample amounted to 62 infants who were divided into 2 groups, namely premature babies (n = 31) and term infants (n = 31). Statistical analysis used is Independent sample t test and Mann-Whitney U test. This study aims to assess the comparison of thyroid function (FT4 and TSHs) between premature infants and term infants at the first examination in the age range of 2 -6 days. The results showed that 90% (28/31) premature infants had hypothyroxinemia with lower FT4 levels than term infants (18.70 ± 6.50, 95% CI). TSHs levels in premature infants were higher than term infants (5.70 ± 5.27, 95% CI). This study concluded that FT4 is better at detecting thyroid function disorders in premature infants while TSHs are better at detecting abnormal thyroid function in term infants.
Child Malnutrition and Family Food Security in the COVID-19 Pandemic Iflan Nauval; Husnah Husnah; Marisa Marisa; Khairunnisa Khairunnisa; Linda Ayu Lestari; Nadya Irena Habib; Talitha Liony
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2796

Abstract

At the beginning of 2020 the world was shocked by a disease that caused death with such easy transmission, namely through the respiratory tract. This disease is caused by a virus called corona. Corona virus is a new type of virus that has now shocked the world community. The problem is that this virus has managed to infect thousands of millions of people globally in a very short time, even humans who do not show symptoms of being infected with the corona virus can also spread it to other humans. In Indonesia itself, the total number of cases caused by the COVID-19 virus is increasing, so the government is trying to contain the spread of the COVID-19 virus. One of the ways that the government has taken to deal with the COVID-19 virus is by implementing large-scale social restrictions (PSBB). People's lives have changed since the implementation of Large-Scale Social Restrictions by the Government. These changes are felt in various fields of the economy, namely income, employment, expenditure and purchasing systems made by the community. As a result, many people cannot work and their income decreases, especially to meet food needs which can cause nutritional imbalances in the community. Expenditure and purchasing systems carried out by the community. As a result, many people cannot work and their income decreases, especially to meet food needs which can cause nutritional imbalances in the community. Expenditure and purchasing systems carried out by the community. As a result, many people cannot work and their income decreases, especially to meet food needs which can cause nutritional imbalances in the community.
Practical Analysis Antibiotics Use for Covid 19 Patients Puri Safitri Hanum; Ni Made Eravikania Putri Darmawan; Didik Hasmono
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2636

Abstract

To evaluate the use of antibiotics and their effectiveness in COVID-19 patients including PCR, body temperature, SaO2, chest X-ray, respiratory rate, leukocytes, CRP, and LOS of COVID-19 patients at Bhayangkara HS Samsoeri Hospital Mertojoso Surabaya. This study is an observational study with a retrospective method in the period June 2020 to February 2021. Data were collected from Medical Records of COVID-19 patients who achieved antibiotic therapy, with standard therapy: antiviral (mild to moderate: Favipiravir-Ritonavir and severe: Remdesivir), antibiotics, vitamins, anticoagulants, corticosteroids, symptomatic and concomitant therapy. The study showed that 37% (25 patients) were female and 67% (41 patients) were male with the highest age range between 30-39 years. Most of the patients were hospitalized for 10-14 days and the longest hospitalization period was 40-44 days. In this study patients with mild cases were the most cases with a total of 36 patients (54%). The results of the analysis based on the 2020 Third Edition of the 2020 COVID-19 Handling Guidelines, the Bhayangkara Hospital Antibiogram data, clinical conditions and laboratory tests occurred in 66 patients (100%). Rational use of antibiotics in accordance with the COVID-19 Management Guidelines 3rd Edition and data from Bhayangkara Hospital antibiogram of 100% and antibiotics can help the healing process of COVID-19 patients proven by negative PCR results (91%), increased body temperature (100%), SaO2 (100%), chest x-ray (45%), respiratory rate (92%), leukocytes (77%), CRP (41%), and LOS.
Soil Quality Index Analysis of Forest Secondary and Palm Oil Plantation Nurul Puspita Palupi; Agus Sarjono; Abdul Hanif
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3995

Abstract

Soil quality greatly determines the ability of the soil in carrying out its functions to support the life of organisms in a sustainable manner. Land use and land management have the role of increasing or decreasing the quality of a land. This research was conducted to determine the index of soil quality in secondary forest land use and oil palm plantations and evaluating the application of the concept of sustainable agriculture to oil palm plantations. This research was carried out from July to October 2019 in Bukit Biru and Loa Ipuh Darat village, Tenggarong and in the Mulawarman University Faculty of Agriculture. This study uses the concept of Minimum Data Set (MDS) with the assessment of several indicators and soil functions. The assessment function is adjusted to the environmental conditions in which the research is conducted. This study shows that secondary forest use has a soil quality index value of 0.638 with Good criteria, and oil palm plantation land use has a soil quality index of 0.592 with Moderate criteria. Oil palm plantations in this study have not yet reached the concept of sustainable agriculture.
The Healing Analysis of II Degree Burn from Surgery Essential Oil Ointment (Curcuma Longa) in Wistar Rats (Rattus Norvegicus) Chen Wei; Florenly Florenly; Dewi Riastawaty Purba; Fioni Fioni
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3474

Abstract

Data in Indonesia the death rate from burns is still high at around 40%, mainly caused by severe burns. The most potential medicinal turmeric plant is its rhizome, which contains the phenolic compound curcumin and essential oils. Some of the benefits of turmeric antioxidants, anti-inflammatory, anti-cancer, acetylcholinesterase activity inhibitors, anti-fungal, and anti-bacterial. This study aims to find out the phytochemical content and effects of Turmeric Essential Oil Ointment (Curcuma longa Linn) in curing grade II burns in Wistar rats (Rattus norvegicus). This type of research is experimental with a pre-post approach and post-test control group design. The study was conducted at Riwandi Pet Shop and Animal House March-May 2021. The research sample is turmeric (Curcuma longa) obtained from a traditional market in the city of Medan and identified in herbarium Medanese (MEDA), Laboratoirum Taxonomy of Plants, Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), University of North Sumatra, Medan. The test animal is a Wistar strain rat with as many as 20 tails divided into 4 treatment groups, so each group consists of 5 rats. The results of the study contained significant differences in the epithelial period of the standard group, 10% turmeric ointment and 15% against the control group. However, in the turmeric ointment group and the standard group, there was no difference in epithelialization periods. This is evident from the value P < 0.05 (Value P = 0.029). The healing effects of burns possessed by Turmeric ointment are both 10% and 15% and nebacetin ointment as standard shows significant differences. Where the wound contraction rate of turmeric ointment is 15% better than nebacetin ointment as standard. But in both turmeric ointments, both 10% and 15% and nebacetin ointment as standard did not show significant differences in the parameters of the epithelial period.

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