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Yudi Her Oktaviono
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Cardiovascular and Cardiometabolic Journal (CCJ)
Published by Universitas Airlangga
ISSN : 27466930     EISSN : 27223582     DOI : 10.20473/ccj.v1i2.2020.31-37
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology
- Adult cardiac surgery - Atherosclerosis - Cardiac imaging - Cardiac prevention - Cardiac rehabilitation - Cardiomyopathy - Cardiovascular immunology and infection - Congenital heart disease - Diabetes mellitus - Dyslipidaemia - Electrophysiological heart disease and arrhythmias - Extracorporeal circulation and cardiac perfusion - Heart failure - Hypertension and hypertensive heart disease - Ischaemic heart disease and coronary artery disease - Metabolic disorders and its linked to cardiovascular diseases - Pediatric cardiac surgery - Pericarditis and pericardial disease - Reactive oxygen species - Rheumatic valvular disease - Vascular disease
Arjuna Subject : Kedokteran - Cardiology and Cardiovascular Medicine
Articles 91 Documents
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Invasive Strategy of STEMI in Patients with TAVB, RBBB, and Dual High-Risk Profiles: Navigating the Challenges of Antithrombotic Therapy – A Case Report Shafira, Aisya Ayu; Hermawan, Hanestya Oky
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 6 No. 2 (2025): Cardiovascular and Cardiometabolic Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v6i2.2025.125-132

Abstract

Background: It is imperative to diagnose and treat acute coronary occlusion as soon as possible, especially in patients with complicated conduction anomalies. Although electrocardiography (ECG) is still the gold standard for diagnosis, it has drawbacks, particularly when conduction abnormalities such as bundle branch block are present. Case Summary:  In this case study, a 60-year-old woman with cardiovascular risk factors and type 2 diabetes had an anteroseptal STEMI that was worsened by RBBB and total AV block. The patient's recovery was complicated by extensive gastrointestinal bleeding after a successful percutaneous coronary intervention (PCI) and the implantation of a stent in the left anterior descending artery. Conclusion: In addition to highlighting the difficulties of striking a balance between dual antiplatelet therapy (DAPT) and reperfusion strategies in a high bleeding risk setting, this also highlights the management of a high-risk STEMI patient with total atrioventricular (AV) block, right bundle branch block (RBBB), and severe gastrointestinal complications. -- Highlights: 1. This case illustrates the complex management of STEMI with total AV block and right bundle branch block, where urgent PCI and temporary pacing achieved rapid hemodynamic stabilization. 2. Post-PCI gastrointestinal bleeding under dual antiplatelet therapy highlights the need for individualized antithrombotic strategies and vigilant post-discharge monitoring in high-risk patients.
Association between HbA1c and Non-HDL-Cholesterol in Type 2 Diabetes Mellitus at a Tertiary Hospital in Indonesia Putri, Karina Widya; Soelistijo, Soebagijo Adi; Prabowo, Gwenny Ichsan
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 6 No. 2 (2025): Cardiovascular and Cardiometabolic Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v6i2.2025.73-82

Abstract

Abstract: Diabetic dyslipidaemia is considered a modifiable risk factor for cardiovascular disease (CVDs). Non-high-density lipoprotein-cholesterol (non-HDL-C) is a better predictive measure of CVD compared to glycosylated haemoglobin (HbA1c) in type 2 diabetic. This study aims to explore the intricate link between these variables, which contribute significantly to the health risks of T2DM, particularly in a clinical environment like Dr. Soetomo's Endocrinology Polyclinic. Material and Methods: This study used a cross-sectional method with observational analytics design to determine the correlation between HbA1c and non-HDL cholesterol in Type 2 Diabetes Mellitus. Data was collected at Dr. Soetomo Surabaya's Endocrinology Polyclinic from April 2022 to May 2023, focusing on medical records of Type 2 Diabetes Mellitus (T2DM) patients with dyslipidaemia. The study involved T2DM outpatients meeting specific criteria and excluded those with incomplete records or stage 5 Chronic Kidney Disease (CKD) diagnosis at the clinic. The data processing utilized the SPSS statistical program to examine the correlation between independent and dependent variables, employing Pearson or Spearman Correlation based on the data's distribution. Results: The study included mostly women (66.67%) averaging 52.11 years old (SD 4.61). Simvastatin was the most prescribed statin (60.92%). Mean values for HbA1c, total cholesterol, HDL, LDL, and non-HDL cholesterol were 8.155%, 217.29 mg/dL, 46.61 mg/dL, 141.37 mg/dL, and 170.68 mg/dL. Most had poor glycemic control and cholesterol ≥ 130 mg/dL. The Spearman test showed a strong positive correlation between HbA1c and non-HDL cholesterol (r=0.534; p<0.001) and a moderate positive correlation with LDL cholesterol (r=0.473; p<0.001). Conclusion: There is a strong correlation between HbA1c and non-HDL cholesterol in Type 2 Diabetes Mellitus. -- Highlights: 1. A significant positive correlation was observed between HbA1c and non-HDL cholesterol levels in patients with Type 2 Diabetes Mellitus, indicating a linked progression of glycemic and atherogenic profiles. 2. The findings support non-HDL cholesterol as a reliable and cost-efficient parameter for assessing cardiovascular risk, complementing or surpassing LDL cholesterol in clinical evaluation.
Technology Acceptance Model (TAM) of TELE-ECG to Screen Cardiovascular Disease in Jayapura Regency, Papua Oktaviono, Yudi Her; Isfandiari, Muhammad Atoillah; Dharmadjati, Budi Baktijasa; Ramadhan, Muhammad; Prabowo, Emil; Ludfy Avianto, Achmad Tri; Muhammad, Raditya Rizki; Tri Saputra, Pandit Bagus
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 6 No. SI (2025): Cardiovascular and Cardiometabolic Journal Special Issue (ACSA 2024)-In Press
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v6iSI.2025.13-22

Abstract

Background: The cardiovascular mortality rate in Papua is still relatively high. This study aims to assess the readiness and benefits of telescreens with tele-ECG on high-risk population based on the Technology Acceptance Model (TAM) theory in Jayapura Regency, Papua. Material and Methods: This cross-sectional study was made based on the Technology Acceptance Model (TAM) questionnaire which was distributed to health workers using a validated Likert scale and analyzed using the Structural Equation Model with LISREL. Result: The results show that the total internet connection is 71% good or very good. Around 77% of respondents felt that telescreening for high-risk cardiovascular disease would be beneficial, with 76% of respondents having the intention to commit to using the telescreening. Conclusion: Internet access in the Jayapura Regency area is quite good and is not an obstacle to providing telescreening with with tele-ECG services. This TAM can be the basis for the development of telescreening for the early detection of high-risk populations so that cardiovascular death can be prevented. - Highlights: This study demonstrates high readiness among healthcare workers in Jayapura Regency to adopt tele-ECG–based cardiovascular screening, with adequate internet connectivity reported in most primary health centers. A majority of respondents perceived tele-ECG as useful, easy to use, and relevant to their clinical practice. Technology Acceptance Model analysis indicates strong intention to use tele-ECG for screening high-risk cardiovascular populations. These findings support tele-ECG telescreening as a feasible and scalable approach for early cardiovascular disease detection in geographically remote and underserved regions
Simultaneous Acute Cardio-Cerebral Infarction: A Double Emergency Case, What Can Physicians Do Best In Rural Hospitals With Limited Facilities? Prasiddha, Kaka Citta; Kurniawan, Chandra; Sudiyoko
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 6 No. SI (2025): Cardiovascular and Cardiometabolic Journal Special Issue (ACSA 2024)-In Press
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v6iSI.2025.1-4

Abstract

Highlights: 1. This case demonstrates the diagnostic and therapeutic challenges of simultaneous acute cardio-cerebral infarction in resource-limited settings. 2. Early recognition and hemodynamic-guided decision-making are crucial to optimize outcomes when both myocardial and cerebral infarction coexist. -- Abstract Background: Cardio-cerebral infarction (CCI) is a rare condition characterized by the simultaneous occurrence of acute myocardial infarction (AMI) and acute ischemic stroke (AIS), for which no standardized treatment strategy has been established. Case Summary: We report the case of a 72-year-old man who presented with left limb numbness for more than three hours and a brief episode of syncope 2.5 hours prior to admission. He had experienced persistent left-sided chest pain for two days. His medical history included hypertension and diabetes mellitus. On examination, the patient was fully conscious (GCS 15) with left-sided muscle weakness (grade 2) and a positive Babinski sign. The Siriraj score was −8.1. Brain computed tomography could not be performed due to limited facilities. Electrocardiography revealed non–ST-segment elevation myocardial infarction (NSTEMI), leading to a diagnosis of concurrent AIS and NSTEMI. Unfractionated heparin was administered to manage NSTEMI, while antiplatelet therapy was withheld pending neuroimaging. Chest pain improved after anticoagulation, but the patient was referred for further diagnostic evaluation and management. Based on the sequence of symptom onset, CCI in this case was most likely caused by cardiac pathology leading to cerebral infarction. Hemodynamic compromise associated with AMI may reduce cerebral perfusion, particularly in patients with long-standing hypertension. Conclusion: Management decisions in CCI should prioritize hemodynamic stability, continuous cardiac monitoring, and infarct location to determine the optimal treatment sequence
Ebstein’s Anomaly with Paraplegia in The Two Lower Extremities: A Surprising Diagnosis in Adult Woman—A Rare Case Report Ryan Ardiansyah; Rinjani, Lalu Galih Pratama
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 6 No. SI (2025): Cardiovascular and Cardiometabolic Journal Special Issue (ACSA 2024)-In Press
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v6iSI.2025.5-12

Abstract

Background: Ebstein's anomaly (EA) is a rare condition of congenital heart disease and a malformation of the tricuspid valve with myopathy of the right ventricle, Ebstein anomaly is estimated to occur at a rate of 0.17 to 0.72 per 10,000 live births and has no correlation with gender or race. Case Summary: We report the rare case in adult women patient from East Lombok West Nusa Tenggara Indonesia, is diagnosed with Ebstein’s Anomaly. The patient came to the emergency department presented with symptoms of paraplegia with palpitation. She had paraplegia until twelve years a go and diagnosis is confirmed by echocardiography with result of sistolic function of LV is normal EF 68%, but diastolic function of LV difficult to evaluate and sistolic function of RV difficult to evaluate, additionally, moderate mitral regurgitation, Thrombus in Right Atrium diameters of 2.4x4.8 cm, Tricuspid valve difficult to evaluate, and high probability of pulmonary hypertension, electrocardiogram (ECG) revealed Atrial fibrilation with rapid ventricular respons and Chest radiography showed a globe-shaped heart, with normal vascularity and a cardiothoracic ratio of above 0.5 is considered abnormal and may indicate cardiomegaly. The patient received medical treatment, which provided significant relief. Conclusion: From this case we wished to point out to show that early screening of congenital heart disease is important to life saving, further research in this case is needed to know that the possible paraplegia due to venous thrombosis of ebstein's anomaly. - Highlights: This rare case highlights an unusual presentation of Ebstein’s anomaly associated with paraplegia, possibly related to venous thrombosis. Early screening and echocardiographic evaluation of congenital heart disease remain essential for timely diagnosis and life-saving management
Dextrocardia and DORV with Recurrent Supraventricular Tachycardia: A Very Rare Condition Putri, Aisyah; Cenisia; Hendrawan, Yuvian; Kikuko, Irawati Hajar; Putri, Alisia
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 7 No. 1 (2026): Cardiovascular and Cardiometabolic Journal - In Press
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Dextrocardia and DORV are rarely congenital heart disease. One of the life-threatening complications of CHD is arrhythmia. Supraventricular arrhythmia is the most common type of arrhythmia in adult patients with CHD. This case report aims to improve current knowledge by providing a clinical description of Dextrocardia and DORV with Recurrent Supraventricular Tachycardia. Case Report: A 24-year-old man who came to our emergency with palpitation and dyspneu. This complaint was a recurring incident that causes the patient to be readmitted to the emergency departement. Clinical examinations showed tachypnea, tachycardia, and cyanosis. Through additional physical and supporting examinations, the patient was diagnosed with dextrocardia and DORV with recurrent supraventricular tachycardia.  Conclusion: One of the most common complications of complex CHD in adulthood is supraventricular tachycardia. CHD can trigger recurrent SVT due to the presence of different anatomical and electrophysiological pathways. This condition is relapsing and became the reason for hospital admission. Appropriate therapies during acute phase and rate control are important to prevent recurrence. Keywords: Dextrocardia; DORV; SVT -- Highlights: 1. This case report describes a rare combination of dextrocardia and double outlet right ventricle complicated by recurrent supraventricular tachycardia, illustrating the complex interplay between structural abnormalities and arrhythmic risk. 2. It emphasizes that altered cardiac anatomy in congenital heart disease can predispose to persistent arrhythmias, requiring careful acute management and long-term strategies to prevent recurrence and repeated hospitalization
The Air Pollution and Its Impact on Cardiovascular Diseases Latif, Hafizah; Wahyudi
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 7 No. 1 (2026): Cardiovascular and Cardiometabolic Journal - In Press
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Air pollution has emerged as a significant global health concern, with over 99% of the world's population exposed to pollutants exceeding WHO-recommended levels. Cardiovascular diseases (CVDs) linked to air pollution include hypertension, atherosclerosis, arrhythmias, and heart failure, driven by mechanisms such as oxidative stress, autonomic imbalance, and systemic inflammation. Indonesia, ranking 18th globally for air pollution, faces severe challenges, with Jakarta recording PM2.5 levels nine times higher than WHO standards. Methods: This literature review synthesizes data from epidemiological studies, meta-analyses, and reports by organizations like WHO and the American Heart Association. It examines the impact of pollutants (PM2.5, NO2, CO, SO2, O3) on CVDs, explores biological pathways, and evaluates mitigation strategies. Data sources include the National Mortality and Morbidity Air Pollution Study (NMMAPS) and the European Society of Cardiology (ESC) guidelines. Aim: The study aims to highlight the cardiovascular risks of air pollution, analyze its pathophysiological mechanisms, and propose actionable strategies for individuals and governments. Recommendations include adopting renewable energy, improving public transport, enforcing stricter emissions regulations, and using protective measures like masks. By addressing air pollution, the study underscores the potential to reduce CVD morbidity and mortality, advocating for coordinated efforts to safeguard public health. --
Left Ventricular Hypertrophy in Borderline and Low-Grade Hypertension: A Narrative Review Gaprindashvili, Tamar; Agladze, Rusudan; Bochorishvili, Inga; Pagava, Zurab
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 7 No. 1 (2026): Cardiovascular and Cardiometabolic Journal - In Press
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v7i1.2026.36-51

Abstract

Left ventricular hypertrophy represents a major response to hypertension that is considered adaptive and is accompanied by cardiac structural and functional remodeling. This focused narrative review integrates data from 26 different references and studies concerning clinical aspects of LVH in borderline and low-grade hypertension. Among the 26 reviewed studies, 6 cohort analyses reported LVH prevalence in borderline hypertension and stage 1 hypertension. It was revealed that echocardiography demonstrated four times greater sensitivity for detecting LVH compared to ECG criteria. At the same time, LVH regression with RAAS inhibitors reduced cardiovascular risk. Emerging tools like speckle-tracking echocardiography and cardiac MRI provided earlier and more precise detection of subclinical LVH. Findings include the independent association of LVH with cardiovascular morbidity/mortality, the importance of myocardial ischemia in adverse outcomes, and the regression of LVH through specific therapeutic interventions. Discussion also includes new information concerning genetic predisposition, molecular pathways, and other advancements in diagnosis. -- Highlights: 1. This review highlights the diagnostic gap in detecting LVH among borderline and stage 1 hypertensive patients. It was found that echocardiography offered roughly four times greater sensitivity than standard ECG, with speckle-tracking echocardiography further identifying subclinical strain abnormalities in patients without overt LVH. 2. It was found that RAAS inhibitors (particularly ARBs) produced the greatest reductions in left ventricular mass, and that LVH regression was associated with a 40% lower risk of major adverse cardiovascular events.
The Correlation Between Active Smoking Behaviour and SYNTAX Score on Male Patients with Coronary Artery Disease Maringka, Kezia Michella Yusak; Ermawan, Romi; Sari, Dian Puspita; Rahmat, Basuki
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 7 No. 1 (2026): Cardiovascular and Cardiometabolic Journal - In Press
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v7i1.2026.1-11

Abstract

Background: This study aimed to determine the relationship between smoking behavior and SYNTAX score in male patients with coronary artery disease (CAD) at the Regional General Hospital of NTB Province. Material and Methods: This observational analytic study used a cross-sectional approach, conducted from August to November 2023 in the cath lab of NTB Provincial General Hospital. A total of 94 male CAD patients diagnosed through coronary angiography were enrolled, divided into smokers and non-smokers. Medical records were reviewed, and SYNTAX scores were calculated using angiography data under the supervision of a consultant cardiologist. The study used consecutive sampling to select eligible patients based on the inclusion and exclusion criteria. Data were analyzed using independent t-tests and ANCOVA. Results: Among the 94 patients in this study, 48.9% had a history of hypertension, 25.5% had DM, and 31.9% had dyslipidemia. The mean age was 57.9 years with a standard deviation of 9.7. The body mass index (BMI) ranged from 18.4 to 34.8, with 39.4% in the normal BMI category. Regarding therapy history, 2.1% had received statin and antiplatelet therapy before angiography. SYNTAX score distribution showed that 57.4% had a low SYNTAX score, 23% had an intermediate score, and 17% had a high score, with a mean of 20.7 ± 11.9. After adjusting for confounding variables, a significant association was found between smoking behavior and SYNTAX score (p = 0.046; mean difference = 4.8). Conclusion: There is a significant difference in SYNTAX score between male CAD patients with smoking behavior and without smoking behavior. Smoking behavior is significantly associated with higher SYNTAX scores. Smoking cessation interventions may help reduce the complexity of CAD. Further research is needed to evaluate the impact of smoking cessation on SYNTAX scores in this population. -- Highlights: 1. This study demonstrates that smoking is linked to more severe and complex coronary artery disease, as reflected by higher angiographic severity scores in male patients. 2. Even after accounting for major cardiovascular risk factors, smoking remains an independent contributor to disease burden, reinforcing its critical role in worsening coronary pathology.
Changes in Nutritional Status of Children with Acyanotic Congenital Heart Disease Six Months After Repair and Intervention Siregar, Ludwina Rouli Hilary; Heroe Soebroto; Hidayat, Taufiq
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 7 No. 1 (2026): Cardiovascular and Cardiometabolic Journal - In Press
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v7i1.2026.12-24

Abstract

Background: Acyanotic congenital heart diseases (CHDs) namely, atrial septal defect (ASD), ventricular septal defect (VSD), and patent ductus arteriosus (PDA) are prevalent in children and often associated with malnutrition due to increased metabolic demands and feeding difficulties. Aims: This study evaluated the incidence, characteristics, and nutritional outcomes of paediatric patients undergoing repair for acyanotic CHD at RSUD Dr. Soetomo in 2023. Methods: A retrospective observational study included 40 children aged 1–13 years with ASD, VSD, PDA, or combinations thereof. Data on age, sex, and anthropometric parameters including weight-for-age (WAZ), height-for-age (HAZ), weight-for-height (WHZ), and BMI-for-age (BAZ) were assessed before and at 1, 3, and 6 months post-repair. Results: PDA was the most frequent diagnosis (50%), with females comprising 60% of cases and most patients (62.5%) under 5 years. Before repair, 71.4% were underweight and 60% were stunted (mean WAZ –2.58; HAZ –2.3). Nutritional recovery occurred gradually; at 6 months, normal WAZ increased to 58.8% and normal HAZ to 65%, though 38.2% remained underweight and 35% stunted. Conclusion: Repair intervention improves but does not fully normalize nutritional status. Ongoing nutritional support and long-term monitoring are essential for optimal recovery in paediatric CHD patients. -- Highlights: 1. Nutritional status among paediatric patients with acyanotic congenital heart disease (ASD, VSD, PDA) significantly improved within 6 months post-repair, especially in weight-for-age and height-for-age indicators, demonstrating the beneficial impact of surgical correction on growth recovery. 2. Despite overall improvement, over one-third of patients remained underweight or stunted six months after repair, emphasizing the need for continued nutritional monitoring and integrated dietary support in post-operative care programs.

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