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INDONESIA
Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang
Published by Pharmaceutical Journal of Indonesia
ISSN : -     EISSN : 2461114X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Jurnal penelitian ini bertujuan untuk mengetahui hubungan tingkat pengetahuan petugas pengelola obat dengan tingkat ketersediaan obat di beberapa Puskesmas Kota Malang. Penelitian yang dilakukan merupakan observasional analitik cross sectional. Teknik pengambilan sampel responden adalah dengan total sampling. Instrumen yang digunakan adalah kuesioner pengetahuan petugas pengelola obat dan lembar pengumpul data tingkat ketersediaan yang dilihat dari data LPLPO
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 166 Documents
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Effectiveness of Anaemia Therapy in Breast Cancer Patients with Chemotherapy-Induced Anaemia at Dharmais Cancer Hospital Jakarta in 2023 Muti, Annisa Farida; Yasya Sabrinanissa; Rahmi, Eldiza Puji; Pradana, Dhigna Luthfiyani Citra
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Chemotherapy-induced anemia is a common complication in breast cancer patients, primarily caused by bone marrow suppression, which inhibits erythropoiesis and reduces hemoglobin levels. Effective management of anemia is crucial in improving patients' quality of life and tolerance to cancer therapy. This study aims to evaluate the clinical effectiveness of anemia therapy, including packed red cell (PRC) transfusion and erythropoiesis-stimulating agents (ESA) administration, in breast cancer patients post-chemotherapy at Dharmais Cancer Hospital in Jakarta. Methods: The study design used was a retrospective observational study with data collected from inpatient medical records throughout 2023. A total of 35 patient records were selected using total sampling technique. Hemoglobin levels before and after anemia therapy were analyzed using paired statistical tests to assess the effectiveness of the therapy. Results: The analysis results showed a statistically significant increase in hemoglobin levels after therapy was administered (p < 0.001). Conclusion: indicating that both PRC transfusions and ESA therapy effectively contributed to correcting post-chemotherapy anemia in breast cancer patients.
Copigmentation of Black Rice Anthocyanin Extract and Steam Soybean Polyphenols: Phytochemical Analysis and Antioxidant Activity Syafitri, Liza; Rais, Ichwan Ridwan; Salamah, Nina
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Black rice (Oryza sativa L. indica) and soybean (Glycine max L. merr) have potential as sources of natural antioxidants due to their bioactive compounds. Objectives: This study aims to evaluate the antioxidant activity of black rice extract co-pigmented with steamed soybean extract and determine the effect of solvent variation on the antioxidant activity. Methods: The extraction process was carried out using several solvent variations, namely 70% ethanol, a combination of 70% ethanol with 3% citric acid solution, and a combination of 70% ethanol with 5% citric acid solution. Extract characterization includes yield, organoleptic properties, total polyphenols, total anthocyanins, and antioxidant activity for black rice extract. Antioxidant activity was measured using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Results: The results showed that black rice extract with a combination of 70% ethanol solvent and 5% citric acid had the highest antioxidant activity with an IC₅₀ value of 136.456±0.022 ppm (medium category), followed by extracts with a combination of 70% ethanol and 3% citric acid (IC₅₀ = 2414±0.003 ppm), black rice extract with 70% ethanol (IC₅₀ = 2621±0.006 ppm), and soybean extract with 70% ethanol (IC₅₀ = 3252±0.006 ppm). Copigmentation of anthocyanin and polyphenol extracts with a ratio of 80:20 (black rice: soybean) produced the strongest antioxidant activity (IC50= 107± 0.0398 ppm) and the highest total polyphenol content (112.87±0.175 GAE/g). Conclusions: This study shows that copigmentation effectively improves the stability and functional activity of the combination of black rice extract and steam soybean extract.
Evaluation of Antibiotics for Inpatients with Acute Respiratory Tract Infections at Tamiang Layang Regional General Hospital in 2023 Nadya Ayu Nida; Hasniah; Ramadhani, Juwita
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

The high rate of acute respiratory infections (ARI) is a crucial health issue, the therapy usually used is antibiotics, but there is still inappropriate use, therefore an analysis is needed to ensure an antibiotic has been used rationally or not. This study aims to identify profiles and evaluate antibiotic use using the ATC/DDD, DU90% and Gyssens methods. Data were collected retrospectively from medical records of Tamiang Layang Regional Hospital in 2023 with a sample of 73 medical records. The results of the study obtained 57.53% of males and 42.46% of females with the highest incidence of 5-14 years old (28.77%), patients who have not attended school 39 patients (33.42%) and 52 patients (71.23%) have not worked and the highest diagnosis of pneumonia as many as 55 patients (75.34%). The antibiotic profile used by patients was ampicillin 26 prescriptions (35.61%), levofloxacin 19 prescriptions (26.02%), ceftriaxone 19 prescriptions (26.02%) and azithromycin 9 prescriptions (12.33%). The total DDD value was 80.82 DDD/100 hospitalizations with the most use being levofloxacin at 40.10 DDD/100 hospitalizations. Antibiotics included in DU90% were levofloxacin, ampicillin and azithromycin. The quality of antibiotic use using the Gyssens method was 54.80% rational prescriptions and 45.20% irrational. The chi-square value obtained LOS value had a relationship with the rationality of antibiotic use (ρ = 0.030).
Duck Egg Shell and Bay Leaf Extracts (Syzygium polyanthum [Wight] Walp.) Toothpaste Development Using Sodium CMC as a Binder ERYANI, MIKHANIA; perwita, tista; aditama, agnis; rashati, dewi; husni, patihul; wijiani, nina
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Toothpaste is a semi-solid preparation that helps shield teeth from bacterial harm by including abrasive compounds and other helpful elements. Duck eggshells are one of the natural materials that contain calcium carbonate as an abrasive, while bay leaves are a plant that hassantibacterial properties. Objectives: This study aims to formulate duck egg shell toothpaste and bay leaf extract (Syzygium polyanthum [Wight] Walp.) with sodium CMC variation concentrations. Methods: toothpaste is formulated with variation CMC concentration are 3% for F1; 4.5% for F2; and 6% for F3 and evaluate its physical properties. The physical properties tests conducted included organoleptic tests, homogeneity, pH, viscosity, spreadability, and foam height. Results: From the research results, there is an effect of varying sodium CMC concentrations on the physical properties of pH, viscosity, spreadability, and foam height, but no effect of varying sodium CMC concentrations on the organoleptic and homogeneity properties. Conclusions: The research indicate that all formulas meet the requirements for the physical property tests of duck egg shell toothpaste and bay leaf extract.
Prescription Redemption and Price-Related Decisions among Hypertensive Patients in Community Pharmacies in Surabaya Deapsari, Fani; Rafif Fidaus, Favian; Charis Aqsha, Aulia; Almaulidia Rahman, Nabila
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Hypertension remains a major public health problem worldwide. Prescription redemption is a critical early step to medication adherence. Objectives:  This study examined prescription redemption behavior, price-related decision-making, and pharmacist consultation behavior among hypertensive patients attending community pharmacies in Sawahan District, Surabaya, Indonesia. Methods: A cross-sectional survey was conducted among 258 adult patients using a structured behavioral questionnaire covering sociodemographic characteristics, clinical profile, prescription redemption patterns, price attention, generic substitution requests, and pharmacist consultation behavior. Results: Most participants reported visiting a pharmacy after physician consultation (82.9%); however, only 46.1% consistently redeemed all medicines listed on the prescription. High price attention was reported by 64.0% of participants, whereas only 16.7% frequently requested generic alternatives. Pharmacist consultation was common (77.5%), particularly among unemployed and newly diagnosed patients. In bivariate analysis, complete prescription redemption was associated with longer duration of hypertension, willingness to pay out of pocket, and not purchasing medicines outside the prescription. Conclusions: These findings suggest that cost awareness does not automatically lead to patient-initiated generic substitution and indicate a need for proactive pharmacist counseling that explicitly addresses affordability, complete redemption, and appropriate generic options.
Effect of Different Types of Sugar and Fermentation Time on Total Alcohol Content of Eco Enzyme Based on Pineapple (Ananas comosus (L.) Merr)and Orange (Citrus x sinensis (L.) Osbeck) Putri, Fitria; Setyowati, Erna; Pratiwi, Sylvia
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Eco enzyme is a fermented product derived from a mixture of organic waste, sugar, and water (3:1:10). Fermented products produce alcohol (ethanol), which can be used as a reference for quality control, regulatory compliance, and biological activity. Several factors can affect alcohol content, including the type of sugar and fermentation time, both of which have not been widely researched. Objectives: This study aims to determine the effects of different types of sugar and fermentation time on the total alcohol content of eco-enzymes derived from pineapple and orange peels. Methods: The eco enzymes formed were evaluated organoleptically (color and aroma), pH, and total alcohol content were determined by the colorimetric method. Results: All samples changed color and aroma, formed sediment, and had a decrease in pH from a range of 5–6 to 3.44–4.22 after fermentation. The average total alcohol content obtained at fermentation after 30, 60, and 90 consecutive days was 2.336%, 3.072%, and 2.149%, respectively. The highest alcohol content was obtained in the 60-day fermentation molasses treatment of 3.512 ± 0.498%. Statistical analysis showed that fermentation time had a significant effect on the total alcohol content of eco enzymes (p < 0.001), whereas sugar type did not (p = 0.129). Conclusions: The results of this study show that fermentation time is an important factor in determining alcohol formation in the eco enzyme.

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