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Moondra Zubir
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INDONESIA
Indonesian Journal of Chemical Science and Technology
Published by Universitas Negeri Medan
ISSN : 26221349     EISSN : 26224968     DOI : -
Core Subject : Science, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology
Jurnal ini mempublikasikan artikel di bidang Kimia yang meliputi penelitian dasar dan terapan. Bentuk Publikasi di Indonesian Journal of Chemical Science and Technology : * Artikel * Review (berdasarkan permintaan Dewan Redaksi) * Communication (berdasarkan permintaan Dewan Redaksi)
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 14 Documents
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Search results for , issue "Vol 7, No 1 (2024): JANUARY 2024" : 14 Documents clear
Effect of Contact Time and Stirring Speed on Biosorption of Lead (II) Using Sugarcane Bagasse Pasaribu, Nur Rizky; Kurniawati, Desy
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56443

Abstract

Lead is a hazardous and toxic metal if it reaches human organs in sufficient doses or if it is present in water. Pb2+ can build up in the brain, causing cancer, disorders of nerve cells, kidneys and mental health as well as problems with male reproduction and resulting in bone irregularities in children. As a result, it is vital to regulate the presence of this metal in water. Biosorption is a heavy metal removal technique that use biomass as an adsorbent. The biosorption method was conducted in this study employing sugarcane bagasse as an adsorbent and batch contacting. Variations in contact duration and stirring speed were tested in this study to determine the influence of contact time and stirring speed on the biosorption process. The study's findings revealed that a contact duration of 60 minutes and a stirring speed of 100 rpm were the best conditions in this research.
GCMS Analysis of Bakong Gayo or Gayo Tobacco (Nicotiana tabacum L) Leaves Extract and Pharmaceutical Uses Supiyani, Supiyani; Saisa, Saisa
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56451

Abstract

Tobacco plants are considered more destructive plants than medicinal plants. This research aims to analyze using GCMS (gas chromatography mass spectrometry) the leaves extract of Bakong Gayo or Gayo tobacco (Nicotiana tabacum L) and its pharmaceutical uses. Extraction of Gayo tobacco leaves with chloroform solvent obtained 14 phytochemical compounds in the form of alkaloids, terpenoids and fatty acids. The phytochemical compounds in Gayo tobacco can be used as antibacterial, anticancer, anti-depressant, antioxidant, sedative, aromatherapy based on references and other potential to be developed as a medicinal plant.
Potential Analysis of Quercetin and Its Derivatives as Inhibitors of Hendra Virus (HeV) Rosyiidah, Nur Anisa; Setiarso, Pirim; Sanjaya, I Gusti Made
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56448

Abstract

This study aims to determine the inhibitory potential of quercetin and its derivatives on the activity of Hendra virus (HeV) 6BK6 protein with its comparator N-Acetyl-D-[1-13C] Glucosamine. This research was carried out using the molecular docking method in order to obtain information related to binding affinity values, inhibition constants, and amino acid residues in the ligand-receptor hydrogen bonds. It was found that the compound quercetin 3-O-xyloside had the lowest binding affinity among the other compounds, namely -6.92 kcal/mol with an inhibition constant of 8.44 µM. In addition, there are four types of amino acid residues in the ligand-receptor hydrogen bonds including ASP304 (1,90 Å), SER301 (2,47 Å), ARG191 (3,18 Å), and MET188 (4.34 Å). In this case it can be concluded that the compound quercetin 3-O-xyloside has been shown to have the potential to inhibit the activity of the HeV 6BK6 protein.
Formulation dan Phyical Stability Test Of Turi Leaf Extract (Sesbania grandiflora L.) Silver Nanoparticle Soap Savitri, Astri Aulia; Amananti, Wilda; Santoso, Joko
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56444

Abstract

One metal that is widely researched is silver (Ag) which can be used as an antibacterial and antifungal. The method that is widely developed is the biological method, also called biosynthesis. Biosynthesis is a synthesis method using media from plant extracts. This research was conducted to determine the best formulation of Ag nanoparticle soap from turi (sesbania grandiflora) leaf extract based on its stability test. To obtain turi leaf extraction using the infusion method, a flavonoid compound test was carried out to determine the flavonoid compound content. After knowing the existence of flavonoid compounds, the wavelength was determined using UV-Vis Spectrophotometry. In the nanoparticle soap formula, a nanoparticle soap preparation was made which was then tested for the physical quality of Ag nanoparticle soap from turi leaf extract (Sesbania Grandiflora L). The gel-shaped preparation has a characteristic oleum rosae odor and a yellow to blackish soap color. Test the homogeneity to see if there are coarse grains on the surface of the soap. The specific gravity test results of all soap formulations meet the criteria for good soap. The high foam value in soap preparations is between 6.1 – 12.5 mM. The results of measuring the absorption values for concentrations of 1 mM, 2 mM, and 3 mM show that the optimum absorption results in liquid soap preparations are a concentration of 3 mM with a wavelength of 300 nm with an absorbance value of 1.105. The research results showed that turi leaf extract (sesbania grandiflora L) had an effect on the physical stability of Ag nanoparticle soap and met the standards set by SNI. Among formulation 1 with a concentration of 0.03, formulation II with a concentration of 0.06 and formulation III with a concentration of 0.09, the turi leaf extract soap preparation showed the best physical properties in formulation 1 with a concentration of 0.03 in the pH stability test.
Synthesis and Characterization of Hexathiosianatoiron(II) [Fe(NCS)6] 4- Complex Compound and Tetrapyridindithiosianatoiron(II) [Fe(NCS)2(Py)4] Complex Compound Febrianti, Fitria; Sutiani, Ani; Jahro, Iis Siti; Nugraha, Asep Wahyu; Fadhila, Nabila Nur
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56440

Abstract

This research aims to synthesize and characterize the complex compounds Hexathiocyanatoiron(II) [Fe(NCS)6] 4- and Tetrapyridinedithiocyanatoiron(II) [Fe(NCS)2(Py)4]. The synthesis of these complex compounds was conducted in the Chemistry Laboratory, Faculty of Mathematics and Natural Sciences, Medan State University, while magnetic susceptibility measurements were carried out using the Magnetic Susceptibility Balance (MSB) instrument in the Inorganic Chemistry Laboratory, Bandung Institute of Technology. The complex compound synthesis involved the reaction of Iron(II) sulfate heptahydrate with Potassium thiocyanate and Pyridine compound in a 1:2 and 1:2:4 molar ratio. The synthesis process was conducted through a direct reaction method in a polar solvent. The obtained results include Hexathiocyanatoiron(II) complex compound, [Fe(NCS)6] 4-, which is pale yellow crystalline with a yield of 32.76%, and Tetrapyridinedithiocyanatoiron(II) complex compound, [Fe(NCS)2(Py)4] which is dark purple crystalline with a yield of 52.62%. These compounds exhibit a melting point of 219℃. Magnetic susceptibility measurements using the MSB instrument revealed a magnetic susceptibility of 6.69 BM (paramagnetic) for the Hexathiocyanatoiron(II) complex[Fe(NCS)6] 4-, and a magnetic moment of 5.61 BM (diamagnetic) for the Tetrapyridinedithiocyanatoiron(II ) complex [Fe(NCS)2(Py)4].
Antibacterial Activity Test of Ag Nanoparticle Soap Turi Leaf Extract (Sesbania grandiflora) Against Staphylococcus aureus Bacteria Rusiana, Della Ayu; Tivani, Inur
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56445

Abstract

Silver metal nanoparticles have biocidal properties as a non-toxic inorganic antibacterial agent. Flavonoid compounds from the Turi Leaf (Sesbania grandiflora) plant extract as a natural bio reductant. In the research, UV-Vis spectrophotometric testing parameters and antibacterial soap preparations were carried out. Synthesis and Characteristics of Silver Nanoparticles were carried out, with soap preparations made into 3 formulas with different variations in Agno3 concentration, namely 1 mM, 2 mM, and 3 mM and antibacterial activity tested using well diffusion. The results of the absorption spectrum of Ag nanoparticles show the highest peak at a value of 280-290 nm. In the antibacterial activity test, the greater the AgNO3 concentration in the Ag nanoparticle soap, the greater the inhibition zone created by Staphylococcus aureus bacteria. The optimum concentration in soap preparations is 3 mM producing a wavelength of 300 nm with an absorbance value of 1.105. In terms of antibacterial activity, the most effective way to inhibit the growth of Staphylococcus aureus bacteria is formulation III, with an inhibitory power of 7.69 cm2 .
Type Design of Continuous Stirred Tank Reactors (CSTRs) for Bath Bomb Lavender Production Nissa, R. Namira Atha
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56441

Abstract

One of the most widely used complimentary bath products is lavender bath bomb, which has a pleasant scent, a foamy feel, and a relaxing effect. This is a chance to expand the production of bath bombs. The manufacture of lavender bath bombs on a large scale (industry) can be done using a continuous stirred tank reactors (CSTRs). This research aims to design a reactor to react the raw materials of lavender bath bomb through mixing reaction. The method used is by conducting computational analysis and calculation of the reactor and its stirrer and mass balance as the basis for calculation using Microsoft Excel. According to the computation results, the examined reactor needs one stirrer with a power of 141 horsepower and a total volume of 7.2334 ft3 with a height of 27.1045 in. These computational and analytical results can describe the production system using the reactor as a learning tool.
Formulation and Physical Stability Test of Shampoo Preparation Combination of Ethanol Extract of Jackfruit Leaves (Artocarpus heterophyllus) and Pandan Leaves (Pandanus Amaryllifolius) with Varying Carbomer Concentrations Kessya, Febrilliani Kharisma; Pratiwi, Rosaria Ika; Febriyanti, Rizki
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56446

Abstract

Hair plays an important role for humans because hair can influence a person's appearance. Pandan leaves (Pandanus Amaryllifolius) contain compounds in the form of alkaloids, flavonoids, saponins, polyphenols, tannins and dyes. In pandan leaves, the compounds that can provide antimicrobial activity are flavonoids and polyphenols (phenols). This research aims to formulate and test the physical stability of a shampoo combining ethanol extract of jackfruit leaves (Artocarpus heterophyllus) and pandan leaves (Pandanus Amaryllifolius) with varying carbomer concentrations. This research method is laboratory experimental. The carbomer concentration used is 0.1%, 0.3%, 0.5%. The research results showed that the shampoo preparation with the best carbomer concentration was formula 3 with a carbomer concentration of 0.5%. Viewed from an organoleptic perspective, namely with a blackish brown color, the typical smell of pandan accompanied by menthol, pH 6, the shampoo preparation obtained is homogeneous and produces the best foam, namely 13.5 cm in formula 3. Keywords: Shampoo, anti-dandruff, pandan leaves, jackfruit leaf extract.
Characterization of Silica Nanoparticles from Pumice as an Aerogel Adsorbent Hidayah, Rahma; Kurniawati, Desy; Alizar, Alizar
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56435

Abstract

Pumice is often found around the banks of rivers, this stone is a type of igneous rock formed from volcanic eruptions. One of the compounds contained in pumice is silica. Therefore, the synthesis of silica nanoparticles from pumice using the sol gel method was used because it is simpler and more efficient in terms of cost and processing time. the initial step was by reacting pumice powder and NaOH at 70°C - 80°C then synthesized by adding 2M HCI to form a gel or white precipitate, soaking in ethanol, teos, hexane solutions was then synthesized to become an aerogel. Silica synthesis results into silica aerogels were characterized by FTIR and XRF. From FTIR silanol and siloxane functional groups were found, and the SiO2 composition increased to 93,299% after synthesis.
Exploration of Lipid Content in Sargassum binderi Algae from the North Coast of Manokwari West Papua Stepanus, Jamius Bin; Kolibongso, Duaitd
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 7, No 1 (2024): JANUARY 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v7i1.56442

Abstract

The aim of this research is to determine the potential of biodiesel from the algae Sargassum binderi from the North Coast of Manokwari by determining the lipid components contained in the algae. Lipid extraction was carried out using the soxhletation method with n-hexane solvent. Lipid percentage was determined via GCMS analysis. The research results obtained 4 lipid components consisting of hexadecanoic acid (palmitic acid), 9,12-hexadecadienoic acid, 9-octadecenoic acid (Z) (oleic acid) and octadecanoic acid (stearic acid) with a percentage of 18.12%, 4.75%, 19.4% and 4.29% respectively. The total percentage of lipid components extracted was 46.56%, almost half of the total extract.

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