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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Articles 5,497 Documents
Factors Associated with the First Sexual Intercourse among Students : Population-Based Study Manasanun Limpavithayakul; Chuthamat Nopparat
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16957

Abstract

Effect of Mannitol Hydration as Renoprotective on Cisplatin Induced Nephrotoxicity (CIN) in Head and Neck Cancer Patients Mareta Rindang, Andarsari; Yunita Dyah, Kusumaningrum; Rosy Nurlita, Hapsari; Dwi Hari, Susilo; Dewi Wara, Shinta
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16958

Abstract

Background: Cisplatin is a cytostatic agent used as treatments in head and neck cancer patients.Nephrotoxicity is one of cisplatin major side effects. This study aimed to evaluate the renoprotectiveeffect of mannitol-hydration administration in head and neck cancer patients who receive cisplatinchemotherapy. Methods: This was a cohort observational study to analyze the renal function of head andneck cancer patients who receives cisplatin before and after mannitol-hydration administration in IRNASurgery and Soekardja Room of Chemotherapy at RSUD Dr. Soetomo Surabaya during June – September2018. The data obtained were BUN, SCr, and eClCr Cockroft-Gault of each cycle. Result: A total of 52patients were evaluated. The average value of creatinine serum, creatinine clearance, and BUN at each cyclewere fluctuate. However, the average value of creatinine serum and BUN were within the normal limit.The result of statistical analysis using paired t-test in those parameters at each cycle were not statisticallysignificant (p > 0,05) after mannitol administration except during first cycle to second cycle the SCr increasedsignificantly and eClCr was decreased significantly (p-value 0,024; 0,006, CI 95% respectively ). At fourthcycle the eClCr also decreased significantly (p value 0,008, CI 95%). Conclusion: The renoprotective effectof mannitol in head and neck cancer patients who receive cisplatin chemotherapy is sufficiently adequatewhich can maintain the value of BUN and creatinine serum of patients at each cycle within the normal limit.
The Function of the State in Providing Health Services: Indonesia Perspective Marif; Nurhaedah; Handar Subhandi Bakhtiar
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16959

Abstract

The function of the state in providing health services is divided into the regulatory function, the controllingfunction, the entrepreneurial function and the supervisory function. In the regulatory function, the statedevelops policies in the field of health services that ensure that all people can enjoy health services. Thestate control function is responsible for the availability of equipment and medicines as well as maintainingthe stability of the flow of health service distribution. In the entrepreneurial function, the state in addition toproviding health services can receive income from health services which can later be used to equalize thecosts of health care dependents, especially for the poor and underprivileged. In the oversight function, thestate is responsible for carrying out full supervision of health facilities in order to optimally provide healthservices to the people.Keywords: State functions, health services, the right to health.
Nonsurgical Management of a Patient with Hypopituitarism Secondary to Nonfunctioning Pituitary Macroadenoma: A Case Report Martino Handoyo; Hermina Novida
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16960

Abstract

Pituitary adenoma is a benign neoplasm of pituitary gland. Pituitary adenoma, particularly a macroadenoma,may produce mass effect symptoms by compressing surrounding tissues. Due to pituitary function as aneuroendocrine organ, pituitary adenoma may also cause multiple endocrine disturbances. The authors reportthe case of a 39-year-old male patient presenting with chronic headache and history of seizure. MRI imagingrevealed pituitary macroadenoma with optic chiasm compression. Further diagnostic workup indicatedsecondary hypogonadism and adrenal insufficiency. The patient was given hormone replacement therapyand was then advised for surgery, but the patient refused any surgical procedure. Subsequent follow-upswere somewhat difficult due to poor patient adherence. Nevertheless, appropriate management of pituitaryadenoma is needed to achieve optimal result.
Assessment of Pesticide Biohazards in Neurodegenerative Diseases; Data Analysis Statistical Study Marwan M. Merkhan; Zeina A. Althanoon; Ahmed A Mohammed; Ibrahim M. Faisal
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16961

Abstract

Background: The initiation of late onset neurodegenerative diseases remains unknown. New researchessuggested that prolonged exposure to pesticides might lead to the initiation of neurodegenerative diseases,but the results were subject to controversy. Aims: The present study aimed to demonstrate an update dataminingto compare published data for studies comparing role of pesticide in induction of neurodegenerativediseases (Parkinson’s diseases, Alzheimer’s diseases, and Amyotrophic lateral sclerosis) Results: A clearassociation has been noticed across different studies regarding correlation between pesticide exposure andParkinson’s disease or Amyotrophic Lateral Sclerosis (Odd Ratio >1), nevertheless, the association wasweaker between exposure to pesticide and the development of Alzheimer’s disease (Odd Ratio close to 1)Conclusions: There is good quality evidence that the impact of pesticide in initiation of neurodegenerativedisease is statistically approved. However, there is inconclusive evidence from randomised controlledtrials to show significant induction of neurodegeneration. More research is needed particularly long-termcontrolled studies on laboratory animals.
The Leptin Concentration Level in Progression of Hand Osteoarthritis Disease Maryam Qais Ahmed; Ghaith Sael Mohammed
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16962

Abstract

Subject :Hand Osteoarthritis (HOA) is know as degenerative cartilage cell disease in joint association withgeneration various inflammatory responses . This disease is more common in geriatric and effected bymany factors such as obesity . Leptin is hormones secreted of fatty tissue involve as mediators in manypathophysiology process , and support inflammation at cartilage of hand joint .Objective of the Study: Role of leptin concentration level in progression of hand Osteoarthritis .Materials and Methods: This study was done on 60 patients with HOA disease and 60 healthy persons(control ), the all subjects age within this study were more than 60 years of both genders .After obtainedserum , immediately used quantity method (immunoassay) for measured level of leptin concentration .Results: This study shows elevation of serum leptin concentration level in HOA group compare with healthycontrol group .Conclusion: This study confirms that serum leptin concentration level can act as support HOA diseaseprogression .
Formulation Herbal Mouthwash Combination Extract of Ginger and Lemongrass as Antibacterial Causes of Halitosis in Diabetes Mellitus Patients Masriadi; Sukmawati; Hasta Handayani Idrus
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16963

Abstract

Background. Ginger and lemongrass are plants known as the king of rhizomes with a healthy stance becauseempirically many have used them as halitosis treatment in people with diabetes mellitus. The researchobjective was to formulate herbal mouthwash from extracts of natural ingredients, namely a combinationof ginger and lemongrass which has the potential as antibacterial causes of bad breath (halitosis) in peoplewith Diabetes Mellitus (DM). Material and Methods. The extraction of the sample will be carried out by amodified extraction method using ethanol and water solvents, then biological activity testing will be carriedout in-vitro with the diffusion method so that the antibacterial activity test against several bacteria that causehalitosis will be tested. Antibacterial sample is an active compound resulting from the extraction process.Bacteria that had been inoculated into the growth medium (NB) were put into sterile soft NA media (0.7%)with a concentration of 10,000.8,000,7,500 and 6,000 ppm, respectively. Results. There is an inhibitoryeffect, on p. gingivalis but the pattern of values is uncertain. A solution of formulation A with a concentrationof 75% occurs inhibition with an inhibition diameter of 15.7%. This inhibitory effect is not an activity offormulation A, because acetic acid also has the ability to inhibit bacteria. In the sample solution with aconcentration of 100% chitosan (w / v), the highest inhibition occurred with an inhibition diameter of 18.7mm / mg of the sample extract. Formulation A with a concentration of 25% (w / v), the lowest inhibitionoccurred. The test solution of formulation A with a concentration of 25% has shown an inhibitory effect onthe growth of Streptococcus mutans. This effect is stronger at concentrations of 100%, 75%, and 50%. Theantimicrobial effect actually increased with an increase in the concentration of the test solution in successionof 25%, 50%, 75%, 100%. Formulation C with a concentration of 10000ppm, 8000ppm, 7500ppm, 6000ppmshowed that the antimicrobial effect actually increased with an increase in the concentration of the testsolution in succession. This shows that there is a strong positive relationship between concentration andinhibition zone. Conclusion. All tests for both formulation A and formulation C using several concentrationsshowed quite good results with the antibacterial activity being directly proportional to the concentration, thegreater the concentration the greater the activity.
The Concordance of Dysmorphic Erythrocyte and Cast Erythrocyte Examination using Flowcitometry, Low Condenser Light Microscope, and Phase Contrast Microscope in Children with Glomerular Hematuria Maya E. Roring; Jusak Nugraha; Risky V. Prasetyo; Ferdy R. Marpaung
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16964

Abstract

Knowledge and Practice Regarding Prevention of Renal Calculi among Non Teaching Staffs of a Selected College of Health Sciences at Mangaluru Maya Shaju; Amala Elsy Mathai; Dina Joseph; Albert Thampi; Jyothi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16965

Abstract

Background and Aim: Mankind has been afflicted by urinary stones and is the most common disease of theurinary tract. It affects all ages, sexes, and races but occurs more frequently in men than in women withinthe age of 20–49 years. Generally, to prevent the first episodes of kidney stone formation or its secondaryepisodes, proper management of diet is required. The study aim to assess the correlation between knowledgeand practice regarding prevention of renal calculi among Non teaching staffs.Methods: A descriptive correlation approach was adopted for the study and by purposive sampling technique95 non-teaching staffs were selected. The data was collected using demographic proforma, structuredknowledge questionnaire and Rating scale. Collected data were analyzed by Descriptive and Inferentialstatistics using SPSS version16.0.Results: Results showed that majority (75.8%) of the subject had average knowledge and 72.6% of thesubjects had good practice towards the prevention of renal calculi. There was a significant correlation(p<0.05) between knowledge and practice among non-teaching staffs regarding the prevention of Renalcalculi.Conclusion: The study concluded Non teaching staffs had average knowledge and good practice towardsprevention of renal calculi.
Financial Obstacles and Disadvantages of E-Learning From The Viewpoint of Dammam Teachers Mayada Abu Alhomos; Nawal.H.Bahtiti; Tasneem Alayed; Omniya Miri
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16967

Abstract

The efforts of containing the novel virus (COVID-19) have begun to show signs of psychological impact onteachers and students across the globe. As a result of the COVID-19 pandemic, many school districts haveclosed for the remainder of the academic year. These closures are unfortunate because, for many students,schools are their only source of trauma-informed care and supports. When schools reopen, they mustdevelop a comprehensive plan to meet their students’ the potential mental health needs as social distancingand awareness campaigns can be a double-edged sword, if handled inadequately. This paper evaluated thechallenges of teachers in Dammam in e-learning during the period of the new coronavirus (COVID-19)global pandemic.