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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 421   422   423   424   425 
The Effect of Artemisia Dracunculus L. on Mitotic Index in Bone Marrow and Spleen Cells of Mice: In Vivo Study Ahmed Hamed Jwaid; Ali Faris Hassan; Ali Abdulhussain Kasim
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14617

Abstract

Artemisia dracunculus L. (tarragon) is a rich source of herbal remedies with antioxidant and anti-inflammatoryproperties. In the present study, the proliferation of bone marrow and spleen cells of mice was evaluated afterextraction of Artemisia dracunculus with 80% of ethanol. Two doses of the extract (500mg/kg body weightand 1000mg/kg body weight) were given to the mice for seven successive days. On day eight, mice weresacrificed and cells from bone marrow and spleen were collected; mitotic index was calculated and resultswere compared with that of methotrexate at a dose 20mg/kg body weight ( positive control ) and distilledwater ( negative control). The results showed that the dose 500mg/kg body weight of Artemisia dracunculusextract caused significant increase in mitotic index in both bone marrow and spleen cells of mice whencompared with negative control. While, the dose 1000mg/kg body weight of Artemisia dracunculus extractcaused significant decrease in mitotic index in both bone marrow and spleen cells of mice when comparedwith negative control.
Anti-Cancer and Acute Toxicity Activity of Benzo[e]Indol-2- Ylidene)-3 -(4-Methoxyphenyl) Imino Propanal Ahmed Jasim Mohammed Gawi; Walaa Najm Abood; Fadhil Lafta Faraj
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14619

Abstract

Background: The new indole Schiff base compound benzo[e]indol-2-ylidene)-3-(4-methoxyphenyl)iminopropanal](2P)was investigated for antioxidant, toxicity and anti-tumor ability for A547 cell, PC3 celland WRL 68 cell.Results: 2P has antioxidant ability for IC50 (75 µg/mL) compared with control ascorbic acid (27 µg/mL).Antitumor ability to 2P for A547 cell and PC3 cell were decreased significantly after treated with 2P in dosedependent manner at 24,48 and 72 hours, while no toxicity effect on the WRL 68 cell. The antitumor effectwas through accelerated apoptosis, the alteration in nuclear morphology. Increasing in the cells membranepermeability, decreasing in the nucleus intensity with the increasing of concentration of 2P compound wasobserved.MMP is disturbed in the apoptosis by forming of permeability and the result was showed that 2P activatedrelease cytochrome c significant higher than control.2P break down the cell cycle progress in G1 phase (P<0.05) compared with control. Conclusion: this result was conducted the new 2P compound has antioxidantand antitumor ability that may be used 2P a new anticancer drug.
Detection of Proteus mirabilis in Healthy, sick and Diarrheal Dogs, Cats and Humans Alaa B. Mohammed; Aseel M Hamzah
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14621

Abstract

The current work was conducted for isolation, identification and epidemiological frequency and distributionof Proteus mirabilis from humans and Dogs, cats, scanning Vitek in addition (PCR) assay was confirmdetect isolates and Api 20E technique is also used in order diagnosis of P. mirabilis then determinationof antibiotics susceptibility pattern of recovered isolates. The human isolates showed that (89.47%) wereresistant Ampicillin, (42.10%) Ofloxacin, (57.14%) Cefoxitin, (57.14%) Gentamycin, (100%) Vancomycin,(57.14%) Chloramphenicol, (89.47%) Trimethoprim, (100%) Amoxiclav, (57.89%) Streptomycin, (100%)Tetracycline, (89.47%) Penicillin, (100%) Erythromycin. The dogs isolates showed resistance (64.28%) wasresistant Ampicillin, (35.71%) Ofloxacin, (46.1%) Cefoxitin, (53.8%) Gentamycin, (64.28%) Vancomycin,(47.3%) Chloramphenicol, (64.28%) Trimethoprim, (64.28%) Amoxiclav, (42.85%) Streptomycin, (64.28%)Tetracycline, (64.28%) Penicillin, (64.28%) Erythromycin, otherwise the cat’s isolates showed resistance(35.71%) were Ampicillin -resistant, for Ofloxacin (35.71%), for Cefoxitin (35.71%), for Gentamycin(35.71%), for Vancomycin (35.71%), for Chloramphenicol (35.71%), for Trimethoprim (35.71%), forAmoxiclav (35.71%), for Streptomycin (35.71%), for Tetracycline (35.71%), for Penicillin (35.71%), forErythromycin (35.71%). The Proteus mirabilis was isolated from 33 out of 195 sample (16.92%) distributedas 19 isolated from human and 14 from Dogs and Cats. The human isolates showed that (89.47%) wereresistant Ampicillin, (42.10%) Ofloxacin, (57.14%) Cefoxitin, (57.14%) Gentamycin, (100%) Vancomycin,(57.14%) Chloramphenicol, (89.47%) Trimethoprim, (100%) Amoxiclav, (57.89%) Streptomycin, (100%)Tetracycline, (89.47%) Penicillin, (100%) Erythromycin.
Cryopreservation of Dama. Dama (Fallow Deer) Semen using Tris Extender Treated with Soya Milk and Omega3 Ali A.Z. Al-Saadoun; Hadi Awaad Hesoon; MSc. Haider F.M. Khashan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14623

Abstract

The experiment was conducted in the Agricultural research’s station due to the College of Agriculture/Al-Muthanna University in the south of Iraq, to study the effect of adding soybean milk and omega3 tothe tris extender on the quality of Dama.Dama (D.Dama) Gazelle semen under cryopreservation- thawingconditions. The semen was collected from four adults males of D.Dama Gazelle using electric ejaculatorsystem .The experiment was contains four treatments :the control treatment using the traditional tris extenderonly , T1.adding 5% soybeans to the tris extender , T2.adding 2% omega3 to the tris extender, T3. Adding5% soybeans + 2% omega3 to the tris extender. It was observed highly significant effect(p? 0.01) of adding5% soybean(T1) and adding 5% soybean+ 2% omega3(T3) to the tris extender on the sperm total motility%and progressive motility % associated with highest viability percentage( explained by the percentage of livesperms) and significant superiority in the results of the HOST test was noticed in this two treatments (T1and T3).This results refers to better cryopreservation success of D. dama Gazelle spermatozoa in particularit was associated with a very good results of acrosome integrity in all treatments, this is the first study in Iraqdeals with cryopreservation of D.Dama Gazelle semen, that helps to application of artificial inseminationand ( for the future) to conservation of the genetic resource for this endangered species.
Impact Evaluation of Gender and Age on Percentage Distribution of Candidiasis and their Control by Medicinal Mushroom in Laboratory Ali H. Hamoudi; Ahmed K. Abdulrazzaq; Kareem T. Shnawa; Mohammed J. Hanawi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14624

Abstract

Biological control represents an important approach for controlling many pathogenic fungi. Pleurotusostreatus is the most promising and effective bioagents against many pathogenic fungi. In this paper seventyclinical specimens were collected from hospitalized patients, who were aged between (1 and 71) years oldfor both genders. The results of this study showed that out of 70 specimens that collected from urine, Skin,Vaginal and Oral specimens, (61) specimens (87.14%) were positive for fungal infections and (9) specimens(12.86%) were negative. Out of (61) positive specimens, (50) specimens (82%) were positive for Candidaspp, (7) specimens (11%) were Trichophyton spp and (4) specimens (7%) were Microsporum spp. Out of(50) positive specimens for candidal infections, Candida albicans was the more prevalence fungus (66%)followed by the fungus Candida glabrata (14%). The maximum infection incidence has been recorded inthe age group of (21- 40) years and the women have been considerably more than the male in all testedage groups. Pleurotus ostreatus culture filtrate affected the growth of Candida spp and the effect had beenincreased with the increasing of the filtrate concentrations. The more sensitive species was C. tropicalis andC. krusei than the other species.
Sinus Tachycardia as a Predictor of Severe Carbonmonoxide Poisoning Ali Kemal Erenler; Tolga Do?an
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14626

Abstract

Introduction: Carbonmonoxide (CO) poisoning is one of the most frequent intoxications in the world. Theheart is one vital organ affected in CO intoxication. In this study, we aimed to investigate characterstics andelectrocardiographic abnormalities of patients with CO poisoning.Material and Methods: In a two-year period, we analyzed patient records admitted to our EmergencyDepartment (ED), retrospectively. Demographical characteristics (age, gender, monthly distribution, sourcesof poisoning, etc), vital signs, laboratory findings, Glasgow Coma Scale (GCS) scores and ECG findingswere investigated. Additionally, treatment method, source of exposure and length of stay (LOS) in the EDwere investigated. Then, patients were divided into 2 groups as to normobaric oxygen therapy (NBO) andhyperbaric oxygen therapy (HBO) groups according to the treatment methods. Two groups were comparedin terms of electrocardiographic abnormalities.Results: Atotal of 75 patients were involved. The most common source of CO poisoning was stoves (n=71,94.6%). The most common complaint was found to be nausea and vomiting (n=24, 32%). Mean GCS scoreof the patients was 14. Mean carboxyhemoglobin levels were found to be 15%, mean saturation was 95.9%.Five (6.6%) of the patients have undergone HBO in addition to NBO. The most common ECG finding wasfound to be normal sinus rythm in 52 patients (69.3%), followed by sinus tachycardia in 10 patients (13.3%),bradycardia in 4 patients (5.3%), ST depression in 2 patients (2.6%). Four of 5 patients who underwent HBOhad tachycardia on ECG.Conclusion: Use of stoves for heating purposes increases the risk for poisoning particularly in wintermonths. Although physicians must be aware of its ischemic effects of CO poisoning on cardiovascularsystem, sinus tachycardia may be a predictor of CO poisoning severity.
Evaluation of Diabetic-Medications Adherence among Diabetic Type 2 Patients Researcher Ali Shlash; Ihsan S. Rabeea
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14627

Abstract

Background : Diabetes mellitus (DM) is a worldwide health illness with deleterious consequences bothmedically and economically. When treated inappropriately, it can cause severe acute and chronic sequels.The purpose of this study was to assess the adherence to diabetic medications type 2 diabetic patients.Method : The study was cross-sectional performed to assess the adherence of diabetic type 2 patientsto diabetic medications. The study population was randomly enrolled from rural and urban regions. Theparticipants of the present study were known cases of diabetic patients attending community pharmaciesof the regions in which the study was conducted. After an explanation of the goal of the study, the patientswere invited to be enrolled in the study. After obtaining of the written consent, the Arabic version of Moriskymedication adherence scale was administered to patients to be reported by them but the exception for illiteratediabetic patients who interviewed by community pharmacists who were trained on the questionnaire.Results: The total number of participants was 200 patients with a mean age of (50.65±8.91) and approximatelyhalf of participants (49.8%) have an age of greater than 50 years. More than 100 participants have primaryand secondary education and about (43%) has higher education. The female participants were less than thethird of the total number (29%) of the sample and the remaining was male. the majority of patients (75.5%)have poor adherence to medications while (21.5%) of participants have medium adherence to diabeticmanagement and only (3%) have high adherence to medications.Conclusion: In the present study, The adherence to diabetes medication was poor in 75.5% of participantsand the most common reason for non-adherence as reported by patients was forgetfulness.
Breast Cancer Screening: Comparison of Screening Modalities in Taiwan Abdallah Ahmed Elbakkoush; Anas Khaleel; Lin Chia-Hsing; Yazan S Batarseh; Husni S Farah; Talal Salem Al-Qaisi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14629

Abstract

Background: Screening for breast cancer is an important method for reducing the death rate in the Westernworld over the past 20-30 years. On this basis, since 2004 , the National Health Bureau of Taiwan has alsobegun providing free screening service. The purpose of the current research is to compare the efficacy of thethree-mammography modalities for breast cancer identification.Methods: Between July 2004 and December 2010, a total of 23,513 eligible women underwent screeningmammography. 6804 of these received screen-film mammography (SFM), 1610 received computedradiography (CR) mammography, and 15,099 received digital mammography (DM). The detection rate ofcarcinoma-in-situ, early detection rate of cancer, and the overall cancer detection rate of each modality wascalculated. To determine the statistical significance of performance differences between these modalitiesChi-square test was used.Results: SFM callback rate was 12.23%, cancer detection rate was 5.29%, Ductal carcinoma in situ (DCIS)detection rate was 1.76%. Computed radiography’s callback rate was 12.67%, with a cancer detection rateof 6.21% and DCIS detection rate of 1.24%. DM has the highest callback rate of 16.2%, but also the highestrate of cancer detection and DCIS detection rate of 9.21% and 3.58% respectively. DM was found to havebetter cancer detection rate and DCIS detection rate as compared to SFM and CR, it is only statisticallysignificant when compared to SFM. Although DM has better cancer and DCIS detection rates, it is alsoassociated with higher callback rate.Conclusions: In terms of image quality and greater contrast, optical mammography has many advantageswhen opposed to screen-film and computed radiography mammography. In the Asian population, wherewomen have higher breast densities, this is particularly vital. The incidence of Taiwanese breast cancer issteadily growing
The Influence of Knowledge, Lifestyle and Culture on the Incidence of Tuberculosis A Literature Review Aloto Ximenes Belo Amaral; Mateus Sakundarno Adi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14630

Abstract

Background: TB is a public health problem whose incidence is still high in Timor Leste. TB is an infectiousdisease which is one of the leading causes of death in the world caused by an infectious agent Mycobacteriumtuberculosis. The purpose of this study was to review scientific articles focusing on the Influence ofKnowledge, Lifestyle and Culture on the Incidence of Tuberculosis. Method: The method used was aliterature review. Articles used as literature review materials came from SagePub, BMC Public Health,Elsevier, Google Scholar, Pubmed, Proquest and others. The articles were selected based on the researchfocus, which was the Influence of Knowledge, Lifestyle and Culture on the Incidence of Tuberculosis.Results and Conclusions: Knowledge is very important in TB control efforts. Good knowledge needs to befollowed by a good perception. Such knowledge is not only for the TB patients but also for the families andhealth workers. Lifestyles that are very risky to increase health vulnerability in TB patients are smoking,drinking alcohol, using illegal drugs, inadequate consumption, living in a slum environment, lack of airventilation, lack of exercise, lack of sleep, urban life, lack of glycemic control, sugar consumption, andliving with TB patients. Cultural influences include inter-racial disparities, culture of seeking local treatmentor not going to health facilities, delay in initial screening, TB sputum examination, lack of PPE, poor localTB surveillance, traditional medicine, stigma and culture carried by
A Rare Case of Cervical Epidural Abscess Post Posterior Cervical Laminotomy with Isolation of Neisseria Meningitides Bacteria Ammar Najim Abood
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14631

Abstract

Spinal epidural abscess is a rare condition, although it requires an urgent surgery to decrease the pressure onthe epidural sac in addition to the other structures of the spinal cannel cord and nerve roots.A 29 years old female entered the clinic with large neck swelling. She also had a history of headache withneck pain, both arm paresthesia with mild fever. Her MRI showed an epidural collection at level of cervical5 to cervical 7 compressing the dural sac narrowing the spinal cannel and extending to the paraspinalintramuscular area in the neck.She had undergone a surgery with a 2cm mid line incision above the swelling mass in order to suck out thepus. In addition, the intermittent Valsalva maneuver was performed to enhance the epidural pus gat out.The culture and sensitivity test to pus indicated a Neisseria meningitides bacterial growth. Penicillin G andcefotaxime as antibiotics were prescribed. Improvement occurred within 2 weeks.Although rare, the isolated Neisseria meningitides spinal epidural abscess requires an urgent treatmentthrough evacuating and decompressing. Spondylodiscitis or collapse may occur, therefore, a surgery forspine correction may be needed, fellow up is recommended in all forms of epidural abscesses.

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