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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 422   423   424   425   426 
Hepatocellular and Immuno-toxicopathological Effects of Acrylonitrile in Albino Male Mice Anas A. Humadi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14632

Abstract

This study to provide details on role of Acrylonitrile (AN) in blood profile and histopathological changes inliver in male albino mice, the aims of current study were detected influence and toxication of AN in the malemice, the present article was include (30 albino mice) divided into 3 groups, the age ranged from 8-9 week.The dose of Acrylonitrile (25mg / kg of BW) and the period of this study 60 days.The hematological examination showed increased in WBCs (9.32±1.11 / 11.802±0.75), Lymphocyte(9.25±2.20 / 11.05±1.95), Neutrophile (5.55±0.88 / 7.03±1.50) and Monocyte (0.19±0.97 / 0.33±0.18) in2nd and 3rd group respectively, while showed decreased in RBCs (6.40±1.11 / 5.82±0.70), PCV (38.65±1.20/ 36.40±2.13), MCV (44.70±1.49 /41.95±0.49), MCH (14.85±1.44 / 10.00±1.84) and Hb (13.24±1.82 /12.63±1.91) in 2nd and 3rd group respectively, The histopathological changes in liver showed extensivenecrosis, thickening and congestion of blood vessels, infiltration of inflammatory cells, mast cell aggregationin hepatocytes, hepatocyte atrophy and extensive areas of abscess in 2nd group, while in 3rd group showedperihyperplastic bile duct, large extensive granuloma, multiple giant cells, dystrophic calcified and hepaticnecrosis.
Risk Factor Analysis for Placenta Retention in Maternal Delivery at the Tenriawaru Regional Hospital in Bone Regency Andi Misnawati; Rosdiana
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14633

Abstract

Placenta retention issues have complications that can endanger mothers after delivery because of theirstrong association with bleeding. This research aims to determine the risk factors for placental retention inmaternal. This research was an observational analytic study with a case-control design with a sample size of68 mothers. The research was conducted at the Tenriawaru Hospital in 2020. Data collection was carried outby interview using a questionnaire. Then it was analyzed using the chi-square test. The results of the researchfor the Age variable (p-value = 0.027) show that there is a relationship between age and the incidence ofplacental retention, with the OR value: 3.4 (CL: 1.26–9.41) and for the parity variable (p-value = 0.44) therewas no relationship between parity and the incidence of placental retention, with the OR value: 0.47 (CL:0.12–1.82). It can be concluded that of the two factors the incidence of placental retention including age andparity, only age is associated with the incidence of retained placenta.
Nanocurcumin Potential Effect of SOD Enzyme and Caspase-3 Expression in Lead-Acetate Induced Rats Ovarian Granulosa Cells Anis Satus Syarifah; Sri Agus Sudjarwo; Hendy Hendarto; Reny I’tishom; Supriyanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14650

Abstract

Aim: This study investigated the potential effect of nanocurcumin on the increase of SOD enzyme expressionand decrease of caspase-3 in lead acetate-induced rats ovarian granulosa cells.Materials and Methods: Forty five female rats were divided into 5 groups, the negative control group (ratsreceiving corn oil, one hour later receiving distilled water), positive control group (rats receiving corn oil,one hour later receiving lead acetate of 40 mg/kg bw) and experimental groups 1, 2 and 3 (rats receivingnanocurcumin 50 mg, 100 mg and 200 mg/kg bw). One hour after administering the nanocurcumin, therats received 40 mg/kg of lead acetate. All groups received oral treatment once a day for 26 days. Onday 27 the rats were sacrificed and the expression of SOD and caspase-3 enzymes were measured usingimmunohistochemical methods.Results: This study found that lead acetate decreased SOD enzyme expression and increased caspase-3. Incontrast, nanocurcumin increased SOD enzyme and decreased caspase-3 expression in lead acetate-inducedrats ovarian granulosa cells.Conclusion: Nanocurcumin has potential as a strong natural antioxidant by affecting the increase of SODand the decrease of caspase-3 cells in lead acetate-induced rats ovarian granulosa cells.
Possible Pain Caused in Judicial Modes of Execution: A Physiological and Pathological Analysis Anjum Hassan; Meenu Gupta
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14653

Abstract

Undoubtedly, the application of Capital Punishment has attracted a torrent of worldwide criticism. Primarilythe cause behind this criticism is the excruciating pain caused by ancient outdated and uncivilised methodslike crucifixion, hanging, beheading, etc., unlike the cotemporary scientific processes and internationalinstruments. In opposition to the backdrop of enumerated counterattacks, most of the developed countriesdevised/formulated and implemented some contemporary procedures like shooting, lethal injection, gaschamber, etc. These contemporary procedures were alleged by the formulating nations to be swift andcausing minimum pain. In this research paper, each of these modern modes have been critically analysedafter reviewing the physiological and pathological aspect of pain associated with each of these methods. Theauthor finds out that these so called modern method do inflict agonizing pain on the convicted offenders.In conclusion the author does suggest that medicalized process of execution may, to some extent, lead topainless killings
Effectiveness of Instructional Program upon Pregnant Women’s Knowledge Suffering from Pregnancy Induced Hypertension Attending to Primary Health Care Centers in Al- Najaf City Anwar Hassan Hanoon; Shukriyia Shadhan Al- Ogaili
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14654

Abstract

Pregnancy induced hypertension is a common obstetric disorder. It is among the leading causes of maternaland fetal mortality and morbidity. This research aims to assess pregnant women’s knowledge regardingpregnancy induced hypertension, and to find out the relationship between pregnant women’s knowledge andtheir demographic and clinical data . A quasi-experimental design is used to investigate the effectivenessof instructional program upon women’s knowledge suffering from pregnancy induced hypertension , fromthe 8th of January to 3th September2020, included 80 pregnant (40 women as study group), and (40 womenas a control group). The current study found that the knowledge of the majority of women about pregnancyinduced hypertension is poor in complication domain specialty before the implementation of instructionalprogram. However, 100% of them have had good knowledge after two weeks of implementation of theinstructional program. The women have developed and improved in their knowledge about pregnancyinduced hypertension. The study revealed that there were high significant in the study group knowledgeregarding the pregnancy induced hypertension in the pre-test and post-test measurements. The study hasconcluded that the instructional program has a positive effect on the study sample blood pressure. Theinstructional program has a positive effect on the study sample knowledge regarding the PIH. Levels ofeducation, monthly income, residential area, occupational status, and the type of family are affect thepregnant’s knowledge regarding the PIH.
The Influence of Roleplay Simulation on the Moral Development of Children Aged 8-9 Years Old Aris Kurniyanto; Ahmad Yusuf
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14655

Abstract

Background : A lack of moral development might increase negative moral behavior. Drama, as a part ofrole-play, can stimulate the moral development of children aged 8-9 years.Objective : The purpose of this study is to explain the effect of role-play on the moral development ofchildren aged 8-9 yearsMethod : This research applied pre-experimental one-group pre-post test design. The population in thisstudy was children aged 8-9 years with a total of 47 children. A sample of 15 respondents was taken usingpurposive sampling. The independent variable in this study is role-play stimulation, while the dependentvariable is the moral development of children aged 8-9 years. Data collection was done using observationsheets, then analyzed using Wilcoxon Signed Rank Test with significance ? = 0.05.Result: Wilcoxon Signed Rank Test shows that stimulation through role-play can influence the moraldevelopment of children aged 8-9 years with p = 0.001.Conclusion: The results of this study conclude that role-play stimulation can improve children’s moraldevelopment.
Dental and Oral Care Treatment Needs in Children with Down Syndrome in Surabaya Ardianti Maartrina Dewi; Tania Saskianti; Mega Moeharyono Puteri
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14656

Abstract

Objective: Aims of this study was to observe dental and oral care treatment needs of Down Syndromechildren who are members of the Parents’ Association of Children with Down Syndrome (POTADS) inSurabaya. Material and Methods: This study used secondary data from dental and oral examinationrecords of total sample 34 Down Syndrome children aged 5-17 years who attended community serviceprogram “SPECIAL CHILDREN DENTAL VISIT -1” from August to October 2017. Results: Only fewsamples showed good oral hygiene though most of them brushed their teeth twice a day which likely relatedto physical and mental limitations. Most samples had cariogenic dietary habits with def-t/DMF-T scorewere below 10. Malocclusion founded can be worsen by oral bad habits which has existed in most samples.Conclusion: From this study it can be concluded that the most indicative treatment for Down Syndromechildren are restorations and extractions.Good collaboration between parents and caregivers is needed toprevent more severe oral health problems which need more complex dental treatment. Children with DownSyndrome are entitled to the opportunity to develop and get special services, including in terms of oralhealth. With good oral health, the quality of life of Down Syndrome children can improve.
Toothbrushing And Dietary Behavior of Children Aged 3–6 Years with Early Childhood Caries in Impoverished Community of Semampir District, Surabaya Ardianti Maartrina Dewi; Satiti Kuntari; Tania Saskianti; Berliana Ayu Prawesti Permatasari; Adinda Putri
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14657

Abstract

Objective: This research aimed to observe tooth brushing and dietary behavior of children aged 3–6years with early childhood caries (ECC) in impoverished communities, Semampir District, Surabaya City.Materials and Methods: This was descriptive observational with cross-sectional design study in 50 samplesof mother whom their children diagnosed with ECC. Research instrument using questionnaires based oncaries risk assessment (CRA) which modified. Results: Most samples showed good tooth brushing behavior,which includes brushing frequency and duration, routines using toothpaste, had tooth brushing initiative andindependently brushing teeth. The majority of samples had poor dietary behavior which includes snackinghabit frequency, time management, fruit and milk consumption. Conclusion: Most children aged 3–6 yearsin impoverished communities, Semampir District of Surabaya already had good brushing teeth behavior, butthey had poor diet which explain high prevalence of caries.
Comparing Fracture Resistance of Provisional Restorations of 3-Unit Fixed Partial Dentures: An in Vitro Study of CAD/CAM versus Indirect Technique Asadollah Ahmadzadeh; Behnam Beheshti; Mohamad Hossein Haghighizadeh
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14658

Abstract

Objective: To compare the indirect and CAD/CAM techniques and using acrylic and composites resins onthe fracture resistance of provisional 3-unit fixed partial dentures (FPDs).Materials and Methods: In in vitro setting, thirty samples were divided into three groups included 10FPDs manufactured indirectly and made of composite based bis-acryl (Protemp 4) resin, 10 FPDs indirectlymilled with polymethyl methacrylate resin (PMMA) and 10 FPDs fabricated by CAD/CAM PMMA blocks.Fracture resistance was measured using universal testing machine (UTM). The master model was made ofNiCr-alloy which designed using CAD/CAM technology.Results: FPDs fabricated using CAD/CAM PMMA blocks showed the highest fracture resistance valuesfollowed by Protemp 4 and then PMMA using indirect method. Statistically significant difference wasfound between the three groups (P=0.001). Bonferroni test was applied for pair wise comparison, in whichthe statistically significant difference was observed between FPDs fabricated by CAD/CAM which madeof PMMA blocks and Protemp 4 and between CAD/CAM PMMA blocks and indirect/PMMA FPDs andbetween indirect/Protemp 4 FPDs and indirect/PMMA FPDs. Hence this suggested that PMMA significantlyhas minimum value of fracture resistance when compared to both CAD/CAM and Protemp 4.Conclusion: This study proved the superiority of CAD/CAM PMMA blocks for fabricating 3-unit FPDsover Protemp 4 and PMMA using indirect method, and the superiority of Protemp 4 over PMMA in termsof fracture resistance using indirect methods
GPx1-rs1050450 Gene Polymorphism Association with End Stage Renal Disease in Type2 Diabetic Patients of Babylon Province/Iraq Asma’a H. Mohamed; Ali H. Al-Saadi; Haider K. Zaidan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14660

Abstract

Background: Glutathione Peroxidase-1 is an antioxidant enzyme, play an important role in defense againstoxidative stress. In Pro198Leu (C/T) polymorphism of Glutathione gene variation which result in loweringenzyme activity increasing microvascular complications of diabetic patients. Aim: This study was aimed toestimate the relationship between GPX1 gene variation and the risk of develop and progression of end stagerenal disease in type I diabetic nephropathy patients. In this study, it has been examined 140 type I diabetesmellitus patients with nephropathy and 40 healthy control. Results: All samples have been genotyped byusing polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) techniques.In diabetic nephropathy patients, there were a significant elevation in in the variation (TT) genotype and (T)allele frequencies compared with control group.Conclusions: Using major Iraqi diabetic patients of Babylon province we studied the transforming effect ofGPX1 gene polymorphism on the risk of development diabetic nephropathy, this study was found that the(TT) genotype of GPX1 SNPs increases the risk of development diabetic nephropathy, while (CC) genotypedecreases the chance for developing disease. These results will gave the way for better perception of thegenetic influencing on the development and progression of diabetic nephropathy.

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