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Indian Journal of Forensic Medicine & Toxicology
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Articles 5,497 Documents
Maternal and Child Health in Underdeveloped Areas and State Borders Yendris Krisno Syamruth; Hari Basuki Notobroto; H Kuntoro
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14923

Abstract

Background: Mother and child are two vulnerable groups in the family. The health of families inunderdeveloped and border areas is still slowly progress. The high degree of maternal and child health ineach family in underdeveloped and border areas is a benchmark for a national’s public health.Purpose: The study aims to explore the various factors that correlate with the health of mothers and childrenin families who live in underveloped and state borders by using the perspective of supply and demand.Methods: The research was conducted with observational analitic by survey in underdeveloped areas andstate border in 3 border districts in 9 sub-districts with 18 villages in Nusa Tenggara Province, Indonesia.There were 396 families selected from the population by multistage random sampling.Results: The results showed that pregnancy examinations or Antenatal Care services, delivery by healthpersonnel in health facilities; Immunization factors and family planning participation are indicators ofMaternal and Child Health, and home environmental factors, healthy lifestyle factors, infectious diseasefactors, non-communicable diseases, socio-economic factors, and accessibility factors are some of thefactors related to MCH.Conclussion: This study concluded that environmental health factors, healthy lifestyle and behavior,infectious and non-communicable diseases, socio-economic, and accessibility factors are related to thehealth of mothers and children in families living in underdeveloped areas and state borders and AntenatalCare services, delivery by health personnel in health facilities; Immunization factors and family planningparticipation were reflective indicators of Maternal and Child Health in families who live in underdevelopedareas and state borders.
A Comparative Study of Patients’ Attitude Before and after Receiving Healthcare Services at Bam Pasteur Hospital Zahra Shaabani; Parsa Mohammad Alizadeh; Farzaneh Sheikhali; Mohammad Reza Rajabalipour; Mohammad Javad Akbarian Bafghi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14924

Abstract

Background: The human attitude to events, including health and disease, and his interpretations determinesthe quality of his life. The purpose of this study was to evaluate the attitudes of patients before and afterreceiving the services of Pasteur Hospital in Bam.Methods: This is a descriptive study. The research population included 110 patients referring to men’ssurgery and women’s surgery who were studied by simple sampling method. The attitude of patientsbefore and after receiving healthcare was measured by a researcher-made questionnaire. Data analysis wasperformed using spss24 software Through descriptive and analytical tests such as one-way ANOVA, twopopulation mean comparison and pair comparison statistical tests.Results: The results of statistical tests showed that the average total attitude score of clients after receivingservices (2.58) was more than the mean of attitude of clients before receiving services (2.41) (p=0.017).Paired t-test showed significant relationship between the attitude score of the patients towards medical staffvisitors (p=0.017) and Patient discharge unit (p = 0.001) before and after receiving the service, but nosignificant relationship was found between the other units.Conclusion: It can be concluded that the attitude of the clients after receiving the services has been positive.Therefore, to improve the delivery of services and to increase the satisfaction of clients in some sectors,managers can be more precise planning to improve quality.
Preoperative Serum CA125 and Plasma Fibrinogen Levels as Predictors of Lymphovascular Space Invasion in Endometrial Cancer Zahraa Dhirar Yousif; Hayder B. Al-Shammaa
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14925

Abstract

Background: Lymphovascular space invasion has been shown to be a predictor of lymph node metastasisand decreased survival in patients with endometrial cancer. Unfortunately, LVSI status is most commonlynot available until after hysterectomy at the time of preparation of the final Pathology report. Therefore;LVSI status represent additional information to be considered in decision making process regarding whetherto perform lymphadenectomy or to deliver adjuvant therapy. Thus, it was important to find biomarkers topredict the risk of LVSI before surgery.Objective: To evaluate the value of serum CA125 and plasma fibrinogen for prediction of lymphovascularspace invasion in women with endometrial cancer.Study Design: A prospective observational cross-sectional study.Settings: was carried out in the Department of Obstetrics and Gynecology/ Baghdad Teaching Hospital, andNursing Home Hospital in Medical City complex, Baghdad, Iraq, over a period of 1 year starting from thefirst of December 2017 to the end of November 2018.Patients and Methods: Fifty-five women with endometrial cancer undergoing surgery were included inthis study. We compared the preoperative level of serum CA125 and plasma fibrinogen with postoperativehistopathological report regarding LVSI, the results were statistically analyzed.Results: (16.4%) of the patients with positive lympho-vascular invasion. CA-125, Fibrinogen, were highlysignificantly increased in patients with positive LVSI. Sensitivity was (88.9%), specificity (95.7%), negativepredictive value (95.0%), positive predictive value (91.0%),and accuracy of the test was (92.3%)whenthe cutoff value for CA125 was (28.75U/ml) while for plasma fibrinogen in cutoff value (317mg/dl)thesensitivity was (100.0%), specificity (95.7%),negative predictive value (100.0%), positive predictive value(95.9%) and the accuracy of the test was (97.8%)Conclusion: The preoperative assessment of serum CA 125 and plasma fibrinogen could be used to predictthe LVSI in endometrial cancer.
Effect of Oxymetholone on The Sperm Quality and Sex Hormone Profile in Male Rats Zahraa Lateef Abd; Bushra Abbas alzubaidi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14926

Abstract

The objective of present study was to evaluated the effect of Oxymetholone drug on sperm parametersand sex hormone in adult male rats. Twenty male rats sexually mature were randomly divided into twogroups; Each group has 10 rats. The treated group administered orally with Oxymethololne drug 5 mg/gbody weight/ day of for 60 days while the control group administered orally normal saline per day. SPSSanalysis of data generated with P< 0.05 considered statistically significant. The results showed a significantdecrease (p <0.05) in the mean sperm count, the motility and viability in treated group compared to control.Also, LH (luteinizing hormone) FSH (follicle stimulating hormone) and T (testosterone) of the treated groupwere significantly lowered compared to the control. The administration of Oxymethylene induces low spermquality with reduction in sex hormone.
A Mini Review on Covid-19 Infection and Severe Outcome on Cancer Patient Zaidi Zakaria; Sameer B. Al-Mhanna; Hafeez A. Afolabi; Oluwafunke T. Afolabi-Owolabi; Rashidat F. Elesho
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14927

Abstract

Introduction December 2019, the world witness a new strand of pathogen known as coronavirus-2 (SARSCoV-2), later recognized as the novel coronavirus disease (COVID-19). By April 1st 2020, the confirmedcases were over 800,000 around the world with over 40,000 fatalities. Individuals with cancer are morevulnerable to COVID-19 impact because of compromised health-status.Methods A comprehensive search method was applied by searching the google scholar using the keywordsto select eligible studies to be included in the reviewResults The findings showed that patients with cancer, especially thoracic malignancies that wereinfected with COVID-19 infection during the hospital stay developed severe cardiorespiratory symptomsthat warranted use of a mechanical ventilator. The cancer patients with COVID-19 had increased rateof hospitalization and a poor outcome as well as a higher risk of mortality when compared to healthyindividuals. It is recommended that cancer patients taking anti-tumour drugs should undergo early screeningfor COVID-19 because the anti-tumour drugs also suppress the immune system. Hence, their dosage shouldbe regulated appropriately in case of COVID-19 co-infection.Conclusion. In risk-mitigation pandemic scenario in COVID-19 period, efforts should be made not tocompromise the prognosis of cancer in these patients by adhering to treatment guideline.
Exosomes and their Role in Immunity, Metabolic, Cardiovascular, Neurodegeneration, Reproduction and Development Zainab Abdullah Waheed; Nadia Habeeb Sarhan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14928

Abstract

Exosomes are produced by an endocytic cellular route which consists of three steps:first: Cellular membranesinvagination forms the endocytic vesicles, then,The inward budding of the endosoma membrane starts atthe second level, and multivesicular bodies emerge.. In third and last step the multivascular bodies combinewith the cell membrane and Produces the substances of the vesicular, exosomes are used to transfer Setcell prostaglandins to specific cells exosomes Represent a new mode of contact between cells, which inmany biological processes may play a significant role, for example, immune response,Transduction ofsignals,antigen presentation- Intercellular communication mediated by exosome Cells usually communicatewith surrounding cells by direct cell-cell touch, involving interaction of the gap between the cell’s surfaceproteins and protein c interactions Communicate with regional cells via induction soluble Factors like:hormones as well as cytokines Improve the transmission of the signals, Electrical and chemical signals. Andalso Exosomes may play a role in the process of metabolic conditions and cardiovascular disorders theywere found to hold metabolites and allowing intra - cellular communication by exosomal miRNA exchangebetween skeletal muscles , adipose tissue, pancreatic b-cells, and the mouse liver and the human .
Serum Heavy Metals Level and OS among e-ic Waste Exposed Zainab Abood Sadoon; Sabah Hussein Enayah
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14929

Abstract

The current study is performed in Thi-Qar Province which included a collection of whole blood samplesfrom e-ic repair workers. The survey questionnaire was used which is a standardized tool for this researchand provides for grouping and processing of data and used standardized research instruments such asquestionnaires and interviews of a larger group of subjects to get a clearer and richer examination of the datanecessary for further analysis. A total of 100 whole blood samples were taken with different ages rangedfrom 16 years up to 56 years. Other study groups were 30 subjects from non-e-waste workers. Daily worktime approximately about 6-8 hours for 1 year up to 30 years. The results showed that the percentage ofdiabetic patients among the e-waste population is only (6.5%) all of the diabetes cases were arise for workerswhose exposure exceeded 10 years. The heavy metals concentrations in the serum were measured by usingatomic absorption spectrophotometry and the levels of (Pb) were unexpected, the mean serum Pb levels(24±54 ?g/L) of non-e-waste workers was near to that of e-waste workers (24.6±34 ?g/L) at (p? 0.05),Cd results reported high concentrations in the serum workers of e-waste (35.4±53 ?g/l) compared withworkers as non-e-waste (9.3±17.2?g/l) at (p?0.05). The results of selenium showed an increase in serum Selevels in both groups, (209.4±195.5 ????????/????) for the exposed workers compares with (178.2±29.5 ????????/????) forunexposed workers. The other important aspect on which the study focused is the SOD1/catalase antioxidantsystem. As the study showed a decrease in SOD1 (15.2±2.8????????/????????) in workers of e-waste proportion incomparison to the comparison group (36.8±60????????/????????) at (p=? 0.05). Also, the catalase concentration waslower in e-waste workers (23.9±8ng/ml) more than (28.8±6????????/????????) at (p? 0.05) in non-e-waste workers.
Association of Single-nucleotide Polymorphisms rs2243250 of IL4 gene in Diabetes Type 1 Patients with Acute Tonsillitis Zainab khidhair Hussain; Bushra Rashid Ibrahim
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14930

Abstract

Diabetes mellitus type 1 one of diseases which is a difficult metabolism condition, it is characterize highlevel of glucose in of the human blood stream and is a consider prolonged autoimmune disease alignmentsever inflammatory factor. The newest studies reveal that innate immunity high role in diabetes type1. Thesamples in this study consist of (135) Iraqi male with diabetes type 1 with acute tonsillitis in three group(G1: 4-18 years, G2: 11-18 years and control) all samples diagnosed by biochemical methods added to theclinical method. Alleles were determined by amplification of the polymorphic site by real time polymerasechain reaction. The result of genotyping study of rs2243250 of IL4 revealed that the T allele frequencyshowed (0.42 %), (0.41%) and (0.69%) in groups G1,G2, control respectively, while the result revealed thatthe allele frequency C in groups G1,G2, control was (0.58%), (0.59%) and (0.31%) respectively. The studycan be concluded that the genetic variation of rs2243250 of IL4 gene was associated with diabetes mellitustype1 comparison in control (healthy women) in Iraqi men.
Adaptability of Biofilm Formation in Streptococcus Pneumoniae to Various Growth Conditions Zainab Rashid Hameed; Anfal Shakir Motib; Adawia F. Abbas
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14931

Abstract

Streptococcus pneumoniae is one of the major general causes of important diseases world-wide such aspneumonia and meningitis with a high morbidity and mortality in adults especially in elderly people.Pneumococcal biofilms are essential for colonization and persistence, and it is important to continue toinvestigate the environmental conditions which affect their formation. This study came to find out theadaptability of biofilm formation in S. pneumoniae that causes pneumonia in Diyala city and diagnose themwith PCR method by using 16SrRNA for pneumococcal detection in addition to the roads bacteriologyculture test. In this study, 192 sputum samples were collected from Bacteriology Unit of Baquba teachinghospital, Chest Diseases Consultation Clinic and Al-Khalis General Hospital. It appeared that 122 (64%)samples showed no growth while 70 (36%) showed positive growth. Streptococcus pneumoniae isolateswere obtained from 32 isolates. The results of this study showed amplify 1500 bp domain of 16SrRNA byPCR, which was positive in 32 (100%). In addition, the PCR product of the samples were sent for sequencingto identify the Streptococcus pneumoniae strains. The results appeared that the strains of S. pneumoniae thatcause pneumonia in Iraq especially in Diyala city are K10 and D39 strains. Biofilm formation assay wasmeasured by using microtiter plate in three different media and the membrane formation was measured atfour times of bacterial growth phases to show the adaptability of biofilm formation in different environmentalconditions in different media culture. Data of the current study showed that the ability of pneumococcal toform biofilm was better when using a poor medium such as nutrient broth, and the highest value was at thestationary phase.
Formal Reconciliation to Adjudge Psychological and Physical Abuses Committed During Civil War in Acehnese Society Zulfan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14932

Abstract

The civil war caused many psychological and physical trauma for common people. As a way to end this suchwar, related parties usually take formal and social measures in peace agreement. In this case, the formationof the truth and reconciliation commission (TRC) in Aceh is one of a task to accomplish after the signingof memorandum of understanding in Helsinki (MoU Helsinki), and the implementation of law number11, 2006 on the Acehnese government. On one side, the situation has urged TRC to be formed in Aceh,however local regulation has not specifically organized the forming of the commission. Reconciliation inAceh comes with its own character by stressing more on the application of religious, custom, and localwisdom approaches without forgetting the effort of truth revealing on some cases of heavy human rightsviolation which occurred during conflict. The Acehnese society is a society who lives with their Islamicvalues and specific custom.