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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 447   448   449   450   451 
Calorie Restriction and Moderate-Intensity Continuous Exercise Decrease Free Fatty Acid Levels and Visceral Fat Weight on High Calorie Diet Female Mice Ahmad Rukhani Lutfi; Lilik Herawati; Widjiati; Gadis Meinar Sari
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14944

Abstract

Objective: This study aimed to analyze the effect of a combination of calorie restriction and moderateintensity continuous exercise on FFA levels and visceral fat weight in female mice exposed to a high-caloriediet.Material and Method: This research was randomized posttest used only control group design with femalemice as the sampl Balb/c mice (Mus musculus), 8 weeks old, 20-30 grams. It was randomly divided into fourgroups, namely C (control group), G1 (moderate-intensity continuous exercise group), G2 (calorie restrictiongroup), and G3 (combination group calorie restriction and moderate-intensity continuous exercise) wherein every group consisted six female mice. Providing a high-calorie diet using ad libitum plus D40 as muchas 3-5% of calories (0.0325 mL/gBB) for 4 weeks. The provision of a high-calorie diet was done usingthe sonde technique. Calorie restriction was done 3x/week in 4 weeks by limiting calorie intake to 50% ofstandard foods. The moderate-intensity continuous exercise was carried out by swimming for 15 minutesplus 6% gBB loading, it was done 3 times/week for 4 weeks. The measurement of cholesterol, visceral fatweight, and FFA level was done at the end of treatments.Results: The results found that the mean of cholesterol of C C (171.00±47.74 mg/dL), G1 (126.00±15.92 mg/dL), G2 (131.50±22.37 mg/dL), G3 (121.17±21.23 mg/dL) dan (p=0.032). The mean weight of visceral fatat C (0.68±0.23 grams), G1 (0.25±0.08 grams), G2 (0.28±0.06 grams), G3 (0.20±0.03 grams) and (p=0.000).The mean FFA levels were at C (1511.34±6.19 µmol/L), G1 (1419.31±53.61 µmol/L), G2 (1458.20±28.89µmol/L), G3 (1451.55±43.77 µmol/L) and (p=0.004).Conclusion: Based on the results of the study, it could be concluded that the provision of calorie restrictionand moderate-intensity continuous exercise significantly reduced cholesterol levels, visceral fat weight, FFAlevels and in female mice exposed to a high-calorie diet
The Effect of Imbalanced Levels of Some Serum Biochemical Elements on Senile Cataract Formation Zeina M. Alsabti; Marwan Talib Joudah; Wisam Talib Joudah; Omar Muayad Al-Naqeeb
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14945

Abstract

Background: Cataract is the clouding of lens which subsequently may impair vision. The main subtypesof senile cataract are cortical, posterior sub-capsular and nuclear sclerosis. Electrolyte disturbance has beenlinked with the development of age related cataract.Aim of the Study: To assess the correlations between the levels of the blood biochemical elements (Ca++,Na+, K+, Cl-) and the formation of senile cataract.Patients & Method: Blood samples of 35 patients of cataract and 35 of non-cataract/ healthy people havebeen analyzed for calcium and electrolytes levels, all cases were female whose age ranged between (50– 70 years). (5 mL) of blood was taken from the patients’ veins for the study. The serum was separatedof each sample by a centrifuge at (4000) rpm for (4 min) and used for the mentioned biochemical exams.(FUJIFILM/ DRI-CHEM NX500i) biochemical analyzer was utilized in the study. The results were obtaineddirectly from the analyzer.Results: In cataract patients group, there was a significant variations in calcium level (high, normal, andlow) as well as sodium level (low and normal) compared to the control. There was no significant differencesin the level of (K+ and Cl-) between two groups.Conclusion: In the current study, there was a significant differences in calcium and sodium level in cataractpatients group compared to the control. These variations might be one of many factors that contribute in theformation of cataract.
Effect of Information, Education and Communication (IEC) on Knowledge and Attitude regarding Premarital HIV and Haemoglobin Genotype Testing among Adolescents Talatu Abdullah; PadmaPriya S; SasiKumar S
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14946

Abstract

Background: Premarital screening is a test done for younger adults and couples considering marriage forprevention of genetic, infectious and blood transmitted diseases. Adolescent and college young adults must beeducated about potentially life-threatening infectious and genetic disorders for the promotion of their health,well-being as well their offspring too. For providing accurate and unbiased education and information, theIEC is considered to be an effective intervention strategy. Materials and Methods: The study was done toassess the effect of IEC on knowledge and attitude regarding premarital HIV and Haemoglobin genotypetesting among adolescents in a selected Pre-University Colleges, Bengaluru. An evaluative approach withquasi experimental pre-test and post-test control group design was used. A study sample comprised of 60adolescents in experimental group and 60 adolescents in control group. The sample was selected usinglottery method of the simple random sampling technique. The Structured knowledge questionnaire and Threepoint Likert scale was used to assess the knowledge and attitude level of adolescents respectively. Results:Study results revealed that the experimental group which received IEC showed significant difference in theimprovement of knowledge (p < 0.001) and the attitude score (p < 0.001). Conclusion: Based on the studyfindings, it can be concluded that IEC is a best strategy to spread awareness through proper use of materialsto young people to achieve a desired positive outcomes in terms of improving knowledge and positiveattitude on prevention of life threatening infectious diseases and genetic disorders.
Psychological Impacts, Hand Hygeine Practices & and Its Correlates in View of Covid-19 among Health Care Professionals in Northern States of India Shalu Sharma; Akoijam Mamata Devi; Deepak
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14947

Abstract

Background: The novel coronavirus disease 2019 presents an important and urgent threat to global health.190 countries with more than 300 000 confirmed cases and 14 510 deaths1. This critical situation, healthcare workers on the front line who are directly involved in the diagnosis, treatment, and care of patientswith COVID-19 are at risk of developing psychological distress and other mental health symptoms andtransmission between people through close contact and droplets2-3.Method: Descriptive correlation survey design was to assess psychological impacts, hand hygiene practices& and its correlates in view of covid-19. Probability Stratified cluster staging sampling techniques were usedto select 320 health care professionals.Result: The findings revealed that the effect of noval coronavirus covid-19 among health care professionals43.8% had mild fear, 45.9% moderate fear, and 10.3% a severe fear, and their mean value (14.58), S.D(6.96) and the variance was 48.54. Level of mild perceived stress was 46.87%, moderate perceived stresswas 44.06% and 9.06% had severe perceived stress their mean value (14.417), S.D (7.09) and variance was(50.38).Researcher is also assessing the level of practice was 94.37% had good practice, 5.62% had weakpractice their mean value (18.22), S.D (3.15) and variance was (9.92) regarding the prevention of novelcoronavirus covid -19 among Health care professionals. The correlation between fear and perceived stresswas intermediate correlation, fear and practice had weak positive correlation and in between perceivedstress and practice was showing weak positive but nearly close to no correlation. Fear was significantlyassociated with workplace was, perceived stress was significantly associated with Gender, No. of familymembers was statistically significant at P<0.05.Conclusion: Novel coronavirus covid-19 was affecting their psychological factors among health careprofessionals those are working in hospitals.
Natural Honey- as an Effective Adjunct in the Management of Radiation Induced Oral Mucositis Karthikeya Patil; M S Vishveshwara; Mahima V Guledgud; Aishwarya R; Prasannasrinivas Deshpande; Nagabhushana Doggalli
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14948

Abstract

Background - Malignancies are second most common cause of death in the world. Betel quid chewing,smoking, alcohol and low socioeconomic status contribute to its high prevalence. Its treatment protocolincludes surgery, radiotherapy, chemotherapy or a combination. Oral mucositis is an unavoidable mostfrequent, painful, distressing clinical side effect of radiotherapy.Methods – The study group consisted of 102 subjects diagnosed with carcinoma of head and neck andplanned for radiotherapy and had developed oral mucositis, among which 51 were in control group and 51in interventional group. The control group received 0.9% normal saline while interventional group receivednatural honey as topical application. Both the groups were evaluated by World Health Organization oralmucositis assessment scale and symptoms were assessed on verbal basis at baseline (I visit) and along withfour follow-up visits at an interval of 10 days, for total period of 40 days by 2 investigators. The studyduration was of 2 years.Conclusion- This study concludes that the topical application of honey can be used as an adjunct inalleviating the symptoms and in effective management of radiation mucositis as it is an easily available,simple, potent and inexpensive agent.
Cheilitis Granulomatosis - A Case Discussion Karthikeya Patil; Mahima V Guledgud; Prasannasrinivas Deshpande; Nagabhushana Doggalli; Mounika Prashanthi N
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14949

Abstract

Introduction: Cheilitis granulomatosa is an idiopathic, cosmetically unpleasant, non-specific, painless,persistent granulomatous inflammation which affects one or both the lips. It is considered under the entityorofacial granulomatosis with very high rate of recurrence inspite of good treatment.Presentation of case: A 45 years old female patient reported with the chief complaint of swelling in theupper and lower lips for 2 years which had gradually increased in size since the onset. The swelling wasasymptomatic, firm in consistency. On histopathological examination the condition was diagnosed ascheilitis granulomatosaDiscussion: Cheilitis granulomatosa is considered as an entity of orofacial granulomatosis. It is asymptomatic,persistent swelling of the lips. The primary goal of management should be elimination of the predisposingfactor. Intralesional corticosteroids are considered as gold standard in the management of conditions. Insevere cases surgical management is helpful.
Bio Functional Evaluation of EGFR Expression as a Prognostic Indicator in Oral Squamous Cell Carcinoma and a Recommendation for Personalized Targeted Therapy with Anti EGFR Inhibitors Karthikeya Patil; Jayashree K; Mahima V Guledgud; Aishwarya R; Prasannasrinivas Deshpande; Nagabhushana Doggalli
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14951

Abstract

Background: Carcinoma is a complex, multifactorial and a devastating disease. Understanding the molecularchanges that leads to disease enables one to develop strategies to prevent, provide an early diagnosis andserve as targets for therapy. Epidermal Growth Factor Receptor (EGFR), a 170-kDa cell-surface proteinis a tyrosine kinase receptor from the ErbB family and is involved in many biological processes thataffect tumour development, growth progression, differentiation, inhibition of apoptosis and developmentof metastasis. Methods: Study included 54 cases of oral squamous cell carcinomas. EGFR expression byimmunohistochemistry has been studied, correlated with clinical parameters, known prognostic factors andpatient survival to note its significance.Conclusion: Head and Neck Squamous Cell Carcinoma (HNSCC) with or without regional lymph nodemetastases, are challenging to treat effectively. The prognosis for the patients with advanced stage of thedisease still remains poor. The correlation of EGFR overexpression with tumour size, grade, stage andsurvival suggests that EGFR expression can be considered as having prognostic significance and is apotential target for therapy with EGFR inhibitors in HNSCC. Further studies are required to assure theviability of EGFR levels in saliva as non-invasive prognostic marker and also as an indicator of recurrence.
Lipoid Proteinosis - A Rarity in An Adult Karthikeya Patil; Sanjay CJ; Mahima V Guledgud; Prasannasrinivas Deshpande; Aishwarya R; Nagabhushana Doggalli
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14952

Abstract

Background: Lipoid proteinosis is a rare genodermatosis with autosomal recessive inheritance. It isa multisystem disorder characterized by progressive deposition of hyaline material in the skin, mucousmembrane and different organs of the body. The disease is presented by dermatological, laryngeal,ophthalmological, and neurological manifestations. Involvement of oral mucosa may lead to xerostomia anddysphagia; involvement of larynx and eyes results in hoarseness of voice at early infancy and moniliformblepharosis. Extracutaneous involvement includes neurological manifestations like psychosis, partialcomplex seizures, anger, panic attacks, and progressive amnesia. Till date around 300 cases have beenreported in literature.Case Report: A 63 years old male patient reported with chief complaints of pain in the right and left cheekregion, difficulty in swallowing food and dryness of mouth.Conclusion: Lipoid Proteinosis requires multidisciplinary opinion and evaluation by dermatologists,ophthalmologists, otolaryngologists, neurologists and psychiatrist. Clinical features and histopathologicalevaluation aids in the confirmation of the disease. Lipoid proteinosis should be considered one among thedifferential diagnosis when patient reports with difficulty in mouth opening, enlarged tongue, difficult inchewing and swallowing.
Efficiency of Chamomile Essential Oils on Sleeping Quality of First-year University Students Pongsak Jaroenngarmsamer; Kittikan Pajongsaleepanya; Phannee Rojanabenjakun; Jatuporn Ounprasertsuk; Tipvarin Benjanirat; Sasipen Krutchangthong; Sunatcha Choawai
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14954

Abstract

Objective: This is the quasi-experimental research proposed to study the efficiency of chamomile essentialoils on sleeping quality of the first-year university student.Methods: The sample was selected on 20 students with poor sleeping quality. The study was done weekly in2 weeks, intervened with chamomile essential oil. Research tools were the 3-parts questionnaires includingpersonal information, quality of sleep and environmentally influencing sleep. Data were analyzed instatistically parameters.Results: The sleeping quality of the 1st year university students in chamomile group, compare mean andstandard deviation of experimental group found that the mean pre-test sleep quality was M = 80.20, SD =6.65, with poor sleep quality overall and after 2 weeks of trial participation M = 55.65, SD = 10.32, whichhad moderate sleep quality. In experiment with the experimental group, it was found that after 2 weeks ofusing chamomile essential oil, the sleep quality of the experimental group improved. According to statisticalcomparison, t = 2.494, p-value = .022.Conclusion: This study uses of chamomile essential oil showed an improvement in the sleep effect of theexperimental group. To be concluded that chamomile essential oils improved the sleeping quality significantlyas the well-known lavender essential oils. However further study in larger group is recommended.
Comparison of Casein Phosphopeptide Amorphous Calcium Phosphate Fluoride and Fluoride Varnish on Remineralization of Early Caries Lesions Around Orthodontic Brackets Vahid Mollabashi; Soussan Irani; Azadeh Kazemisaleh; Sheida Gharagozlou; Maryam Seyedtabib
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14955

Abstract

Objectives: Orthodontic treatment increases the risk of caries and enamel white spot lesions incidence onthe buccal surface of teeth. This study aims to compare the effect of Casein PhosphoPeptide AmorphousCalcium Phosphate Fluoride and fluoride varnish on remineralization of white spot lesions around orthodonticbrackets.Materials and Methods: In this in-vitro study, 60 premolars teeth were etched for 15 seconds. Then bracketswere bonded with Relicane bond. All teeth were immersed in a demineralization solution for 4 days.The lower part of the bracket was painted with nail polish to prevent the effect of a remineralizing agentto serve as a control group. The teeth were divided into 4 groups, Group 1: treated with fluoride varnish for3 weeks (one-time application), Group2: treated with fluoride varnish for 6 weeks (two-time application),Group 3: treated with casein phosphopeptide and amorphous calcium phosphate with fluoride (CPP-ACPF)for 3 weeks (twice a day), Group 4: treated with CPP-ACPF for 6 weeks (twice a day). Remineralizing agentwas applied on the occlusal of bracket for every tooth Area.then the depth of specimens in treatment and control groups was measured by AutoCAD 2007. Pair-T testand repeated measured ANOVA were used for data analysis by SPSS 23.Result: There was no statistically significant difference between each group of treatment. However, meanremineralization depth in group fourth and mean remineralization area in group three were higher than othergroups.Conclusion: Fluoride varnish and CPP-ACPF have the potential to treat the white spot lesion which iscreated during orthodontic treatment. According to less fluoride varnish use, it seems this substance is abetter option in case of patient’s cooperation is not good.

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