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Indian Journal of Forensic Medicine & Toxicology
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Core Subject : Health,
Articles 5,497 Documents
Risk Factors of the Elderly Falling in Public Hospitals: A Systematic Review Study Masoumeh Otaghi1, Zahra Mohammad-Niakan2, Sanaz Aazami1, Ali Khorshidi3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3185

Abstract

Background: Falls are the most common and problematic issue of old age. There is the possibility of falls among the elderly in the hospitals. The present study was conducted to determine the risk factors for falls in the elderly in hospitals through systematic review. Method: This is a systematic review based on the PRISMA protocol. The IranMedex, SID, Magiran, IranDoc, Medlib, Pubmed, Scopus, Web of Science, Science Direct, Medline and Google Scholar databases were searched for keywords in the time frame of 1994-2017. Results: The mean age was 64-81 years old and the number of elderly people varied from 88 to 28524 people. Of these studies, six studies were performed in the acute care unit, three studies in the elderly care unit, three studies in the surgical and clinical department, one study in the rehabilitation department, one study in the psychiatric department and other studies were performed in several parts of the hospital. The results of this study referred to individual and external factors as risk factors for the falls in the elderly in the hospital. The use of medications, physical problems, and psychological problems were the most common risk factors for falls in the elderly. Conclusion: In acute care, chronic care, psychiatric care, and elderly care units, there are many risk factors for the falls in the elderly due to their physical and mental status. Identifying and resolving these risk factors may provide safety for the elderly.
Effect of Web-Based Early Diagnosis of Dental and Oral Diseases with Validity Level of Dentist Final Diagnosis in Public Health Center, Makassar, Indonesia Masriadi1, Dolly Indra2, Harlinda2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3186

Abstract

Background. One of the organs of the body that is lacking attention is the teeth and mouth, whereas maintaining healthy teeth and mouth is very important, because the nerves of the teeth are related and directly affect the nerves of other organs. The development of information technology that is so advanced has entered the world of health, namely to detect early dental and oral diseases by using an expert system. Making an expert system is not to replace the expert itself but can be used as a very experienced assistant. There is a need to solve this problem so that people can know how to deal with diseases related to teeth and mouth. The various information supporting factors in this study by building an expert system with three methods are Certainty Factor (CF), Dempster Shafer (DS) and Bayes Theorem to diagnosis early dental and oral disease events and determine the effect of expert systems in increasing the validity level of dentist diagnosis. Material and Method The type of research used was an observational method in a cross-sectional study design. The sampling method uses total sampling. The study was conducted in September-January 2020. The number of sampling was 200 people. This research consists of three stages are the making of an application system, application testing, and the final stage is a statistical test. The data analysis technique used in this study is Chi-square and validity test. Results. The results of the analysis of the relationship between the value of accuracy with the validity of the doctor’s diagnosis found variable diagnosis doctor have p value (0.013), DS value, CF and Bayes Value are the same p (0,000) <p (0.05). Conclusion. Applications built using the CF, DS and Bayes Theorem methods can be used by users to detect dental disease early before making further examinations to a specialist. The test results given by the system are the same as the results given by experts (dentists). The system of early diagnosis of dental and oral diseases has a very significant effect on the level of validity of the dentist final diagnosis.
Association between Intelligence Level and Handicap Degree in Epilepsy Patients Meity Meiliyanny Beslar1, J. Eko Wahono1, Isti Suharjanti1, Paulus Sugianto1, Riani Wisnujono1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3187

Abstract

Background:. Epilepsy correlates with high limitation value, disability and function loss which can give negative impact to patient’s quality of life. This negative impact correlates with either epilectic seizures (motoric, sensory and behavior) or effects of anti-epileptic drugs that can cause cognitive impairment, which in this case is intelligence aspect with handicap in epilepsy patients. We determined correlation between intelligence level and handicap degree in epilepsy patients. Methods: The research was conducted in patients of Neurological Department of Dr. Soetomo General Hospital, Surabaya, Indonesia, who met inclusion and exclusion criteria, consecutively from July 2013-December 2013. Intelligence test was conducted using Standard Progressive Matrices (SPM) test, while test on handicap degree was conducted using Subjective Handicap Epilepsy (SHE) test. Results: There were 40 research subjects (19 females and 21 males) with average age of 30.9±9.6. The average score of SHE was 70.08±16/69, while the average score of SPM was 88.53±10.34. There was a weak positive correlation and statistically significant correlation between SPM and SHE scores (r = 0.345 and p = 0.029). Conclusion: There was a correlation between intelligence level and handicap degree in epilepsy patients.
Effect of Glutamine Before Gets Cisplatin on Aif and Bcl-2 in the Evidence of Apoptosis Cell Tubulus Proximal in Rats Kidney of Rattus Norvegicus Strain Wistar Michael Lumintang1, Endang Joewarini1, Sunarni Zakaria2, Gunawan Widodo3, Imam Susilo4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3188

Abstract

Background: Increased incidence of cancer in the world also increases the use of chemotherapy agents. Cisplatin is one of the most effective chemotherapy agents, often used for the treatment of various solid tumors. The therapeutic effect of cisplatin significantly increased with increasing dosage. Aim: The aim of the study was to investigate the role of glutamine in the prevention of apoptosis in proximal renal tubular epithelial cells administered by cisplatin chemotherapy, via an intrinsic caspase-independent apoptotic (AIF). Methods: The study was enrolled thirty male Wistar rats. The rats were divided into three groups of treatments, group A (negative control), group B has given intraperitoneal cisplatin dose of 20 mg/KgBB, group C administered the intravenous injection of glutamine 100 mg/KgBB for 7 days. Results: Analyzed ANOVA, mean expression of BCL-2 group B = 56.80 ± 4.39 than group A (control) = 63.7 ± 5.53 decreased not significant (p = 0.06), and mean expression of BCL-2 group C = 113.30 ± 8.92 increase significant compared to group A = 63.7 ± 5.53 (p = 0.000001) and group B = 56.80 ± 4.39 (p = 0.000001). The average AIF expression group C = 236.20 ± 17.58 decreased significantly compared to group B = 309.50 ± 8.08 (p = 0.000001). The average number of group apoptosis C = 151.80 ± 21.87 decreased significantly compared to group B = 255.20 ± 27.82 (p = 0.000001). Conclusion: Glutamine can inhibit the expression of AIF, increase BCL-2 expression, and decrease apoptosis of epithelial cells of the renal proximal tubules given cisplatin.
Association between Soluble Contents CD40 Ligand (sCD40L) and Acute Coronary Syndrome (ACS) Mirza Elita1, Muhammad Aminuddin1, Jusak Nugraha1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3189

Abstract

Background: Acute coronary syndrome (ACS) is a manifestation of coronary heart disease (CHD), which the leading cause of death in Indonesia. CD40 ligand (CD40L) stored in alpha platelet granules will be rapidly transferred to the surface when the platelets are activated and subsequently released from the surface as a soluble CD40 ligand (sCD40L). Soluble CD40 ligand (sCD40L) acts as a bridge between the inflammatory process, atherosclerosis, and thrombosis. This study aims to study the relationship between sCD40L levels and the incidence of ACS in patients with chest pain in Dr.Soetomo General Hospital, Surabaya. Method: Research subjects were 40 patients with chest pain who came to Emergency Room at Dr.Soetomo General Hospital, Surabaya. The patients were grouped based on the diagnosis of ACS and non-ACS with the electrocardiogram and troponin T. Serum levels of patients that examined by sCD40L with enaminelinked immunosorbent assay (ELISA) method from Quantikine®. Results: Twenty-six (65%) were diagnosed with ACS and 14 (35%) were non ACS. The diagnosis of ACS includes ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI), and unstable angina (UA), with the highest proportion being STEMI at 15 (57%). Spearman correlation test of sCD40L level with ACS incidence got correlation coefficient rho (?) = 0.52 (p = 0.001). Conclusion: There was a moderate positive correlation between sCD40L levels and ACS incidence in patients with chest pain.
The Potential Role of Radiology in Diagnosis of Traumatic Versus Non-Traumatic Cerebral Hemorrhages for Medicolegal Application Mohamed Khairy1, Dina A. Shokry2, Ehab Abdelhaleem3, Reham Nafad Elbendary2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3190

Abstract

Background: Radiography is traditionally used as a complement tool for forensic examination. CT applications became widely used. Traumatic cerebral hemorrhage occurs in up to 15% of patients following head injury and non-traumatic cerebral hemorrhage accounts for up to 44% of all strokes. These two disorders are therefore very common. So there is a need for accurate diagnosis of cerebral hemorrhage form medicolegal aspect. This study aims to differentiate between traumatic and non-traumatic cerebral hemorrhage by using CT. Methods: This prospective study, was conducted on 100 patients with intracranial hemorrhage and divided in two equal groups (traumatic and non-traumatic cerebral hemorrhage) both groups were examined by CT head and the results were analyzed. Results: There was statistically significant difference between traumatic and non-traumatic cerebral hemorrhage groups in CT finding as regard type of hemorrhage with epidural, subarachnoid and intraventricular with P value (0.001, 0.005 and 0.001) respectively. Also according to site of hemorrhage in frontal lobe and subcortical with P value (0.001) equally. Conclusion: we conclude that equation Function (f) = - 0.976 (constant) + 2.873(Epidural) + 2.017 (Subarachnoid) - 0.416 (Intraventricular) + 0.984 (Frontal) -3.047 (Subcortical) If the function (f) = + values, it will be traumatic hemorrhage and if the function (f) = - values it will be pathological hemorrhage
Comparison of Saffron versus Fluoxetine in Treatment of Women with Premenstrual Syndrome: A Randomized Clinical Trial Study Mohammad Nemat-Shahi1, Atefeh Asadi2, Mahbobeh Nemat-Shahi3, Davood Soroosh4, Shakiba Mozari5, Hamid
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3191

Abstract

Background: Premenstrual syndrome (PMS) is a set of physical and psychological symptoms such as mood disability, breast tenderness, food craving, fatigue, and depression. Fluoxetine and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) usually are being administered for these patients. This study aimed to evaluate the effect of saffron plant in terms of its anti-inflammatory and anti-depressant effects compared to fluoxetine. Materials and Method: This study was a three-blind clinical trial that was carried out on working women and their relatives. Firstly, 164 patients with the premenstrual syndrome were selected, and they were randomly divided into two 82-person groups, including those who received fluoxetine and those who received saffron. Next, both groups were treated for two months. The data were collected in two stages through a self-designed questionnaire (on day 5 of menstrual cycle) and validated questionnaires of PRISM and Beck at the end of the period. Results: It was indicated that similar to fluoxetine, the use of saffron in PMS reduced the symptoms such as abdominal bloating, depression, and mood swing, but the latter could better relieve the breast and abdominal pain than fluoxetine. Conclusion: It was concluded that the use of medicinal herbs such as saffron could be effective in reducing the symptoms and they might cause fewer side effects than chemical drugs.
Comparison of the Effects of Passiflora Incarnata and Piroxicam in opioids withdrawal-Induced Myalgia and Anxiety: A randomized Clinical Trial Mohammad Nemat-Shahi 1, Seyyed Mehdi Mir Mohammadi 2, Davood Soroosh3, Atefeh Asadi 4, Samaneh Nakha
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3192

Abstract

Background: Non-steroidal analgesics are the most commonly used analgesics for pain relief in opioids induced withdrawal. One of the herbal remedies that reduce muscle pain, anxiety, and fatigue is Passiflora Incarnata (P.incarnata). In this study, we compared Piroxicam and P. incarnata in withdrawal-induced myalgia and anxiety. Materials and Method: This was a clinical trial carried out on 43 candidate patients for maintenance treatment with methadone. The individuals were randomly divided into two groups. The control group was prescribed piroxicam capsule (10 mg every 12 hours), while the intervention group received drops of P. incarnata (10-15 drops three times a day), until symptoms of withdrawal were resolved (7 to 10 days). In the first, 3rd, sixth, and ninth days of treatment, the patient’s vital signs, myalgia (visual acuity), and anxiety (Beck test) were recorded and analyzed. Results: The results of this study revealed that the flower drops resulted in a reduction in myalgia (mean score of 5.4± 0.79 on the first day decreased to 1. 3 ±0.5 on the ninth day), but there was no significant difference in comparison with Piroxicam (p=0.705). Further, P. incarnata significantly reduced the anxiety caused by withdrawal (p =0.001). Conclusion: P. incarnata drop can be used to reduce the pain and anxiety caused by the drug’s withdrawal.
Hematological Changes in Blood of Smokers of Cigarettes and Nargyle Mohammed S. Hussain1, Nuhad Mohammed Hamid2, Mohammed Qais Al-Ani1, Belal K. Muden1, Mustafa J. Hama
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3193

Abstract

The current study aimed at determining the effect of smoking cigarette and Narghile at some of bloody variables and Vitamin D in a sample of young smokers aged 20-35 in Ramadi.The study included complete blood count (C.B.C) tests including:Total White Blood Cell and Red Blood Cell Count, determination of the concentration of total hemoglobin and calculation of Platelet Count.Calculation of RBC Indicators: “mean corpuscular hemoglobin” (MCH), “Mean Corpuscular Hemoglobin Concentration” (“MCHC”) and Mean red blood Cell Volume (MCV). The study also evaluated the concentration of vitamin D. Results showed that: A rise in the number of white blood cells and red blood cells, as well as a high concentration of hemoglobin and platelet count in smokers.An increase in the volume of red blood cells, mean hemoglobin concentration, and Mean Corpuscular Hemoglobin Concentration in smokers’ blood. Decreased concentration of vitamin D .
Correlation between Hyperglycemia Stress and Short-Term Memory Function in Thrombotic Stroke Patients Muhammad Hamdan1, Riani Wisnujono1, Yudha Haryono1, Abdulloh Machin1, Dian Puspitarini1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3194

Abstract

Background: Hyperglycemic stress is associated with a disorder of the entire cognitive domain in the early phase of stroke, which is memory impairment. Acute changes in blood glucose are known to affect the cerebral blood flow. Objectives: To determine the relationship between stress hyperglycemia with short-term memory function in thrombotic stroke patients. Method: An observational analytic research with the case-control with a patient’s of 72-hour onset thrombotic stroke that went to the Emergency Unit and was admitted to the Neurology Department of Dr. Soetomo General Hospital from January to December 2014. 42 subjects were enrolled (21 subjects in the case group and 21 subjects in the control group). The sampling of the study was conducted according to the cases that came in succession until the achievement of the subject was determined. Results: After bivariate and multivariate analysis, hyperglycemic stress had no significant correlation to memory function (p = 0.525) and OR 0.667 (CI95% = 0.190-2.334). There was a significant correlation between educational level and cognitive function (p = 0.003) also between hypertension and cognitive function (p = 0.019). Conclusion: Stress Hyperglycaemia has no significant relationship with memory function. Education levels and hypertension have a significant correlation with memory function.

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